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Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2017, Volume 60, Issue 4, pp. 1247 - 1261
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 04/2005, Volume 313, Issue 1, pp. 199 - 206
Journal Article
Organic Letters, ISSN 1523-7060, 04/2004, Volume 6, Issue 9, pp. 1453 - 1456
A simple, high-yielding synthesis of 2,4,5-trisubstituted imidazoles from 1,2-diketones and aldehydes in the presence of NH4OAc is described. Under microwave... 
ORGANIC-SYNTHESIS | ACID | ASSISTED REACTIONS | SCOPE | CHEMISTRY, ORGANIC | SARCODICTYON-ROSEUM | ANTAGONISTS | ALKALOIDS | Aldehydes - chemical synthesis | Ketones - chemical synthesis | Ketones - chemistry | Aldehydes - radiation effects | Ketones - radiation effects | Molecular Structure | Imidazoles - chemical synthesis | Microwaves | Aldehydes - chemistry
Journal Article
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2004, Volume 45, Issue 25, pp. 4873 - 4876
Functionalized quinoxalines and heterocyclic pyrazines are expediently prepared in excellent yields (69-99%) from common 1,2-diketone intermediates under... 
Microwave | Quinoxaline | Pyrazine | pyrazine | CHEMISTRY | CHEMISTRY, ORGANIC | quinoxaline | microwave | BIOLOGICAL-ACTIVITY
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2010, Volume 20, Issue 2, pp. 531 - 536
A parallel synthesis approach was employed in the exploration of a quinolone carboxylic acid series of selective M positive allosteric modulators, identifying... 
Positive allosteric modulator | M 1 | M-1 | ALZHEIMER-DISEASE | CHEMISTRY, MEDICINAL | MUSCARINIC RECEPTORS | CHEMISTRY, ORGANIC | DISCOVERY
Journal Article
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2003, Volume 44, Issue 6, pp. 1123 - 1127
By the application of microwave technology, a general protocol has been developed for the rapid synthesis of diverse 3,5,6-trisubstituted 1,2,4-triazines in... 
DIELS-ALDER REACTIONS | CHEMISTRY, ORGANIC
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2003, Volume 13, Issue 2, pp. 273 - 276
A new class of p38 antagonists based on 3,4-dihydropyrido[3,2,-d]pyrimidine scaffold has been developed. These inhibitors exhibit unprecedented selectivity... 
CHEMISTRY, ORGANIC | CELLS | CHEMISTRY, MEDICINAL | STRUCTURAL BASIS | PROTEIN-KINASE | ENDOTOXIN
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2003, Volume 44, Issue 24, pp. 4495 - 4498
In a 'one pot' microwave reaction, an acyl hydrazide-tethered indole underwent a 3-component condensation to form a triazine, followed by an inverse-electron... 
DIELS-ALDER REACTIONS | INDOLE | CHEMISTRY, ORGANIC
Journal Article
Modern research in inflammation, ISSN 2169-9682, 05/2014, Volume 3, Issue 2, pp. 48 - 58
A series of N -nitro-N -substituted guanidines has been prepared as potential inhibitors of the human Nitric Oxide Synthase (NOS) isoforms. The reported... 
Nitric Oxide Synthase (NOS) | isoforms | Nitro-guanidines | selective inhibitors
Journal Article
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