Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (24) 24
genome-wide association study (17) 17
index medicus (17) 17
female (16) 16
male (16) 16
medicin och hälsovetenskap (16) 16
medical and health sciences (15) 15
polymorphism, single nucleotide (15) 15
aged (14) 14
genetics (14) 14
genetic aspects (13) 13
research (12) 12
risk (12) 12
risk factors (12) 12
adult (10) 10
genetic predisposition to disease (10) 10
genetics & heredity (10) 10
middle aged (10) 10
cardiovascular diseases (8) 8
case-control studies (8) 8
cardiovascular disease (7) 7
coronary artery disease - genetics (7) 7
epidemiology (7) 7
genome-wide association (7) 7
polymorphism, single nucleotide - genetics (7) 7
studies (7) 7
gene expression (6) 6
genomes (6) 6
klinisk medicin (6) 6
metaanalysis (6) 6
population (6) 6
aged, 80 and over (5) 5
article (5) 5
clinical medicine (5) 5
cohort studies (5) 5
diabetes mellitus, type 2 (5) 5
diabetes mellitus, type 2 - genetics (5) 5
diagram consortium (5) 5
follow-up studies (5) 5
genetic variation (5) 5
genotype (5) 5
health aspects (5) 5
insulin (5) 5
medicine (5) 5
physiological aspects (5) 5
susceptibility loci (5) 5
type 2 diabetes (5) 5
abridged index medicus (4) 4
african americans (4) 4
alleles (4) 4
atherosclerosis (4) 4
biology (4) 4
cardiac & cardiovascular systems (4) 4
cardiovascular diseases - genetics (4) 4
coronary artery disease (4) 4
diabetes (4) 4
drug development (4) 4
european continental ancestry group (4) 4
expression (4) 4
genetic loci (4) 4
genetic loci - genetics (4) 4
genomics (4) 4
giant consortium (4) 4
hypertension (4) 4
kardiologi (4) 4
magic investigators (4) 4
mendelian randomization (4) 4
meta-analysis (4) 4
myocardial-infarction (4) 4
blood pressure (3) 3
blood pressure - genetics (3) 3
blood-pressure (3) 3
cardiac and cardiovascular systems (3) 3
cardiogram consortium (3) 3
cholesterol (3) 3
confidence intervals (3) 3
development and progression (3) 3
developmental biology (3) 3
dk/atira/pure/subjectarea/asjc/1300/1311 (3) 3
european continental ancestry group - genetics (3) 3
fasting - blood (3) 3
genome-wide association studies (3) 3
heart (3) 3
heart attacks (3) 3
heart-disease (3) 3
hypertension - genetics (3) 3
insulin - blood (3) 3
insulin-resistance (3) 3
loci (3) 3
meta-analysis as topic (3) 3
quantitative trait loci (3) 3
research article (3) 3
single nucleotide polymorphisms (3) 3
stroke - genetics (3) 3
usage (3) 3
0604 genetics (2) 2
11 medical and health sciences (2) 2
acs, acute coronary syndrome (2) 2
adolescent (2) 2
africa - ethnology (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
by Schunkert, Heribert and König, Inke R and Kathiresan, Sekar and Reilly, Muredach P and Assimes, Themistocles L and Holm, Hilma and Preuss, Michael and Stewart, Alexane F. R and Barbalic, Maja and Gieger, Christian and Absher, Devin and Aherrahrou, Zouhair and Allayee, Hooman and Altshuler, David and Anand, Sonia S and Andersen, Karl and Anderson, Jeffrey L and Ardissino, Diego and Ball, Stephen G and Balmforth, Anthony J and Barnes, Timothy A and Becker, Diane M and Becker, Lewis C and Berger, Klaus and Bis, Joshua C and Boekholdt, S. Matthijs and Boerwinkle, Eric and Braund, Peter S and Brown, Morris J and Burnett, Mary Susan and Buysschaert, Ian and Carlquist, John F and Chen, Li and Cichon, Sven and Codd, Veryan and Davies, Robert W and Dedoussis, George and Dehghan, Abbas and Demissie, Serkalem and Devaney, Joseph M and Diemert, Patrick and Do, Ron and Doering, Angela and Eifert, Sana and Mokhtari, Nour Eddine El and Ellis, Stephen G and Elosua, Roberto and Engert, James C and Epstein, Stephen E and de Faire, Ulf and Fischer, Marcus and Folsom, Aaron R and Freyer, Jennifer and Gigante, Bruna and Girelli, Domenico and Gretarsdottir, Solveig and Gudnason, Vilmundur and Gulcher, Jeffrey R and Halperin, Eran and Hammond, Naomi and Hazen, Stanley L and Hofman, Albert and Horne, Benjamin D and Illig, Thomas and Iribarren, Carlos and Jones, Gregory T and Jukema, J. Wouter and Kaiser, Michael A and Kaplan, Lee M and Kastelein, John J. P and Khaw, Kay-Tee and Knowles, Joshua W and Kolovou, Genovefa and Kong, Augustine and Laaksonen, Reijo and Lambrechts, Diether and Leander, Karin and Lettre, Guillaume and Li, Mingyao and Lieb, Wolfgang and Loley, Christina and Lotery, Anew J and Mannucci, Pier M and Maouche, Seraya and Martinelli, Nicola and McKeown, Pascal P and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Merlini, Pier Angelica and Mooser, Vincent and Morgan, Thomas and Mühleisen, Thomas W and Muhlestein, Joseph B and Münzel, Thomas and Musunuru, Kiran and Nahrstaedt, Janja and Nelson, Christopher P and Nöthen, Markus M and Olivieri, Oliviero and ... and CARDIoGRAM Consortium and Cardiogenics and the CARDIoGRAM Consortium
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 4, pp. 333 - U153
We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762... 
HEART-DISEASE | DESIGN | POLYMORPHISMS | METAANALYSIS | MYOCARDIAL-INFARCTION | VARIANTS | CHOLESTEROL | GENETICS | GENETICS & HEREDITY | EXPRESSION | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Genome-Wide Association Study | Coronary Artery Disease - etiology | Gene Frequency | Humans | Middle Aged | Risk Factors | Male | Case-Control Studies | Alleles | Coronary Artery Disease - genetics | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genetic aspects | Disease susceptibility | Research | Single nucleotide polymorphisms | Coronary heart disease | Health aspects | Risk factors | Studies | Genomes | Gene expression | Chromosomes | Meta-analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
by Dupuis, Josée and Langenberg, Claudia and Prokopenko, Inga and Saxena, Richa and Soranzo, Nicole and Jackson, Anne and Wheeler, Eleanor and Glazer, Nicole and Bouatia-Naji, Nabila and Gloyn, Anna and Lindgren, Cecilia and Mägi, Reedik and Morris, Anew and Randall, Joshua and Johnson, Toby and Elliott, Paul and Rybin, Denis and Thorleifsson, Gudmar and Steinthorsdottir, Valgerdur and Henneman, Peter and Grallert, Harald and Dehghan, Abbas and JanHottenga, Jouke and Franklin, Christopher and Navarro, Pau and Song, Kijoung and Goel, Anuj and Perry, John and Egan, Josephine and Lajunen, Taina and Grarup, Niels and Sparsø, Thomas and Doney, Alex and Voight, Benjamin and Stringham, Heather and Li, Man and Kanoni, Stavroula and Shrader, Peter and Cavalcanti-Proença, Christine and Kumari, Meena and Qi, Lu and Timpson, Nicholas and Gieger, Christian and Zabena, Carina and Rocheleau, Ghislain and Ingelsson, Erik and An, Ping and O´Connell, J.R and Luan, J and McCarroll, Steven and Payne, Felicity and Roccasecca, R.M and Pattou, François and Sethupathy, Praveen and Ardlie, Kristin and Ariyurek, Yavuz and Balkau, Beverley and Barter, Phil and Beilby, John and Ben-Shlomo, Y and Benediktsson, Rafn and Bennett, Amanda and Bergmann, Sven and Bochud, Murielle and Boerwinkle, Eric and Bonnefond, Amélie and Bonnycastle, Lori and Borch-Johnsen, K and Böttcher, Yvonne and Brunner, Eric and Bumpstead, Suzannah and Charpentier, Guillaume and IdaChen, Yii and Chines, Peter and Clarke, R and McOin, Lachlan and Cooper, Matthew and Cornelis, Marilyn and Crawford, Gabe and Crisponi, Laura and Day, Ian and Geus, Eco and Delplanque, Jerome and Dina, Christian and Erdos, Michael and Fedson, Annette and Fischer-Rosinsky, Antje and Forouhi, Nita and Fox, Caroline and Frants, Rune and GraziaFranzosi, Maria and Galan, Pilar and Goodarzi, Mark and Graessler, Jürgen and Groves, Christopher and Grundy, Scott and Gwilliam, Rhian and Gyllensten, Ulf and Hadjadj, Samy and Hallmans, Göran and ... and DIAGRAM Consortium and Global BPgen Consortium and Anders Hamsten Procardis Consortiu and GIANT Consortium and MAGIC Investigators and Anders Hamsten on behalf of Procardis Consortium and MAGIC investigators and the MAGIC investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Näringsforskning and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 02/2010, Volume 42, Issue 2, pp. 105 - 116
textabstractLevels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide... 
CIRCADIAN CLOCK | DISEASE RISK | TRIGLYCERIDE LEVELS | INSULIN-RESISTANCE | GENETICS & HEREDITY | BETA-CELL DYSFUNCTION | PLASMA-GLUCOSE | MODEL ASSESSMENT | FOLLOW-UP | GENOME-WIDE ASSOCIATION | ESSENTIAL COMPONENTS | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Reproducibility of Results | Quantitative Trait, Heritable | Diabetes Mellitus, Type 2 - genetics | Humans | Gene Expression Regulation | Genetic Loci - genetics | Databases, Genetic | DNA Copy Number Variations - genetics | Fasting - blood | Adolescent | Alleles | Polymorphism, Single Nucleotide - genetics | Adult | Blood Glucose - genetics | Blood Glucose - metabolism | Child | Homeostasis - genetics | Quantitative Trait Loci - genetics | Type 2 diabetes | Homeostasis | Physiological aspects | Genetic aspects | Research | Insulin | Health aspects | Risk factors | Studies | Hyperglycemia | Diabetes | Sample size | Meta-analysis | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals
by Dastani, Zari and Hivert, Marie-France and Timpson, Nicholas and Perry, John R. B and Yuan, Xin and Scott, Robert A and Henneman, Peter and Heid, Iris M and Kizer, Jorge R and Lyytikäinen, Leo-Pekka and Fuchsberger, Christian and Tanaka, Toshiko and Morris, Anew P and Small, Kerrin and Isaacs, Aaron and Beekman, Marian and Coassin, Stefan and Lohman, Kurt and Qi, Lu and Kanoni, Stavroula and Pankow, James S and Uh, Hae-Won and Wu, Ying and Bidulescu, Aurelian and Rasmussen-Torvik, Laura J and Greenwood, Celia M. T and Ladouceur, Martin and Grimsby, Jonna and Manning, Alisa K and Liu, Ching-Ti and Kooner, Jaspal and Mooser, Vincent E and Vollenweider, Peter and Kapur, Karen A and Chambers, John and Wareham, Nicholas J and Langenberg, Claudia and Frants, Rune and Willems-Vandijk, Ko and Oostra, Ben A and Willems, Sara M and Lamina, Claudia and Winkler, Thomas W and Psaty, Bruce M and Tracy, Russell P and Brody, Jennifer and Fouchier, Sigrid W and Hovingh, G. Kees and Boekholdt, S. Matthijs and Kastelein, John J. P and GLGC Investigators and DIAGRAM Consortium and MAGIC Consortium and MuTHER Consortium and Global B Pgen Consortium and MAGIC investigators and Procardis Consortium and DIAGRAM+ Consortium and GLGC Consortium and GIANT Consortium
PLoS genetics, ISSN 1553-7390, 2012, Volume 8, Issue 3, p. e1002607
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes... 
POPULATION | GENETIC-BASIS | VARIANTS | INSULIN-RESISTANCE | LIPID CONCENTRATIONS | GENETICS & HEREDITY | RISK | RECEPTOR | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Gene Expression | Genetic Predisposition to Disease | Genome-Wide Association Study | Glucose Tolerance Test | Diabetes Mellitus, Type 2 - genetics | Humans | African Americans | European Continental Ancestry Group | Male | Cholesterol, HDL - genetics | Adiponectin - blood | Asian Continental Ancestry Group | Metabolic Networks and Pathways | Adiponectin - genetics | Insulin Resistance - genetics | Female | Polymorphism, Single Nucleotide | Waist-Hip Ratio | Type 2 diabetes | Physiological aspects | Development and progression | Genetic aspects | Research | Metabolism | Health aspects | Blood proteins | Meta-analysis | Medical research | Cardiovascular disease | Drug therapy | Insulin | Metabolic disorders | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans
by Palmer, N.D and McDonough, C.W and Hicks, P.J and Roh, B.H and Wing, M.R and Sandy An, S and Hester, J.M and Cooke, J.N and Bostrom, M.A and Rudock, M.E and Talbert, M.E and Lewis, J.P and Hottenga, J.J and de Geus, E.J.C and Willemsen, G and Boomsma, D.I and Ferrara, A and Lu, L and Ziegler, J.T and Sale, M.M and Divers, J and Shriner, D and Adeyemo, A and Rotimi, C.N and Ng, M.C.Y and Langefeld, C.D and Freedman, B.I and Bowden, D.W and Posthuma, D and Penninx, B.W.J.H and Sladek, R and DIAGRAM Consortium and MAGIC Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Näringsforskning and Umeå universitet and Medicin
PLoS ONE, ISSN 1932-6203, 2012, Volume 7, Issue 1, p. e29202
African Americans are disproportionately affected by type 2 diabetes (T2DM) yet few studies have examined T2DM using genome-wide association approaches in this... 
FASTING GLUCOSE | COMMON VARIANTS | TCF7L2 GENE | LARGE-SCALE ASSOCIATION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | LINKAGE ANALYSIS | STAGE RENAL-DISEASE | TISSUE FACTOR | HOMEODOMAIN PROTEIN | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | African Americans - genetics | Genotype | Male | Case-Control Studies | Diabetes Mellitus, Type 2 - ethnology | Validation Studies as Topic | Adult | Female | Aged | Polymorphism, Single Nucleotide | Cohort Studies | Type 2 diabetes | Chronic kidney failure | Analysis | Genes | Genomics | African Americans | Genetic aspects | Genomes | Medical and Health Sciences | Medicin och hälsovetenskap | Haplotypes | End-stage renal disease | Physicians | Science | Biochemistry | Single-nucleotide polymorphism | Epidemiology | Population genetics | Consortia | Precision medicine | Atherosclerosis | Genetics | Diabetes mellitus (non-insulin dependent) | Lupus | Diabetes mellitus | Gene expression | Minority & ethnic groups | Disease control | Loci | Nephropathy | Genotyping | Insulin resistance | Replication | Diabetes | Kidney diseases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease
by Wild, Philipp S and Zeller, Tanja and Schillert, Arne and Szymczak, Silke and Sinning, Christoph R and Deiseroth, Arne and Schnabel, Renate B and Lubos, Edith and Keller, Till and Eleftheriadis, Medea S and Bickel, Christoph and Rupprecht, Hans J and Wilde, Sandra and Rossmann, Heidi and Diemert, Patrick and Cupples, L Adrienne and Perret, Claire and Erdmann, Jeanette and Stark, Klaus and Kleber, Marcus E and Epstein, Stephen E and Voight, Benjamin F and Kuulasmaa, Kari and Li, Mingyao and Schäfer, Arne S and Klopp, Norman and Braund, Peter S and Sager, Hendrik B and Demissie, Serkalem and Proust, Carole and König, Inke R and Wichmann, Heinz-Erich and Reinhard, Wibke and Hoffmann, Michael M and Virtamo, Jarmo and Burnett, Mary Susan and Siscovick, David and Wiklund, Per Gunnar and Qu, Liming and El Mokthari, Nour Eddine and Thompson, John R and Peters, Annette and Smith, Albert V and Yon, Emmanuelle and Baumert, Jens and Hengstenberg, Christian and März, Winfried and Amouyel, Philippe and Devaney, Joseph and Schwartz, Stephen M and Saarela, Olli and Mehta, Nehal N and Rubin, Diana and Silander, Kaisa and Hall, Alistair S and Ferrieres, Jean and Harris, Tamara B and Melander, Olle and Kee, Frank and Hakonarson, Hakon and Schrezenmeir, Juergen and Gudnason, Vilmundur and Elosua, Roberto and Arveiler, Dominique and Evans, Alun and Rader, Daniel J and Illig, Thomas and Schreiber, Stefan and Bis, Joshua C and Altshuler, David and Kavousi, Maryam and Witteman, Jaqueline C.M and Uitterlinden, Andre G and Hofman, Albert and Folsom, Aaron R and Barbalic, Maja and Boerwinkle, Eric and Kathiresan, Sekar and Reilly, Muredach P and OʼDonnell, Christopher J and Samani, Nilesh J and Schunkert, Heribert and Cambien, Francois and Lackner, Karl J and Tiret, Laurence and Salomaa, Veikko and Munzel, Thomas and Ziegler, Andreas and Blankenberg, Stefan and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 08/2011, Volume 4, Issue 4, pp. 403 - 412
BACKGROUND—eQTL analyses are important to improve the understanding of genetic association results. We performed a genome-wide association and global gene... 
Genome-wide association studies | Genetic variation | Genomics | eQTL | Gene expression | Coronary artery disease | LIPA | eSNP | coronary artery disease | WOLMAN-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | CHOLESTEROL | LOW-DENSITY-LIPOPROTEIN | ATHEROSCLEROSIS | genetic variation | RISK | HEART-DISEASE | COHORTS | GENETICS & HEREDITY | LYSOSOMAL ACID LIPASE | genomics | genome-wide association studies | EXPRESSION | gene expression | Genetic Predisposition to Disease | Genome-Wide Association Study | Coronary Artery Disease - etiology | Humans | Endothelium, Vascular - physiopathology | RNA, Messenger - analysis | Monocytes - metabolism | Gene Expression Profiling | Case-Control Studies | Genetic Variation | Sterol Esterase - genetics | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 10 | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Secretory Phospholipase A(2)-IIA and Cardiovascular Disease
by Holmes, Michael V and Simon, Tabassome and Exeter, Holly J and Folkersen, Lasse and Asselbergs, Folkert W and Guardiola, Montse and Cooper, Jackie A and Palmen, Jutta and Hubacek, Jaroslav A and Carruthers, Kathryn F and Horne, Benjamin D and Brunisholz, Kimberly D and Mega, Jessica L and Van Iperen, Erik P. A and Li, Mingyao and Leusink, Maarten and Trompet, Stella and Verschuren, Jeffrey J. W and Hovingh, G. Kees and Dehghan, Abbas and Nelson, Christopher P and Kotti, Salma and Danchin, Nicolas and Scholz, Markus and Haase, Christiane L and Rothenbacher, Dietrich and Swerdlow, Daniel I and Kuchenbaecker, Karoline B and Staines-Urias, Eleonora and Goel, Anuj and van 't Hooft, Ferdinand and Gertow, Karl and de Faire, Ulf and Panayiotou, Anie G and Tremoli, Elena and Baldassarre, Damiano and Veglia, Fabrizio and Holdt, Lesca M and Beutner, Frank and Gansevoort, Ron T and Navis, Gerjan J and Mateo Leach, Irene and Breitling, Lutz P and Brenner, Hermann and Thiery, Joachim and Dallmeier, Dhayana and Franco-Cereceda, Anders and Boer, Jolanda M. A and Stephens, Jeffrey W and Hofker, Marten H and Tedgui, Alain and Hofman, Albert and Uitterlinden, Ane G and Adamkova, Vera and Pitha, Jan and Onland-Moret, N. Charlotte and Cramer, Maarten J and Nathoe, Henik M and Spiering, Wilko and Klungel, Olaf H and Kumari, Meena and Whincup, Peter H and Morrow, David A and Braund, Peter S and Hall, Alistair S and Olsson, Anders G and Doevendans, Pieter A and Trip, Mieke D and Tobin, Martin D and Hamsten, Anders and Watkins, Hugh and Koenig, Wolfgang and Nicolaides, Anew N and Teupser, Daniel and Day, Ian N. M and Carlquist, John F and Gaunt, Tom R and Ford, Ian and Sattar, Naveed and Tsimikas, Sotirios and Schwartz, Gregory G and Lawlor, Debbie A and Morris, Richard W and Sandhu, Manjinder S and Poledne, Rudolf and Maitland-van der Zee, Anke H and Khaw, Kay-Tee and Keating, Brendan J and van der Harst, Pim and Price, Jackie F and Mehta, Shamir R and Yusuf, Salim and Witteman, Jaqueline C. M and Franco, Oscar H and Jukema, J. Wouter and de Knijff, Peter and Tybjaerg-Hansen, Anne and Rader, Daniel J and Farrall, Martin and Samani, Nilesh J and ... and Avdelningen för kardiovaskulär medicin and Endokrinmedicinska kliniken and Linköpings universitet and Institutionen för medicin och hälsa and Hjärt- och Medicincentrum and Östergötlands Läns Landsting and Hälsouniversitetet
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A(2) (sPLA(2))-IIA in cardiovascular disease. Background Higher circulating... 
EVENTS | drug development | RISK | ACUTE CORONARY SYNDROMES | cardiovascular diseases | Mendelian randomization | TRIAL | epidemiology | genetics | EPIC-NORFOLK | SERUM-LEVELS | INHIBITOR | HEALTHY-MEN | ARTERY-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | ACUTE CORONARY SYNDROME | ENZYMES | ASSOCIATION | TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1
by Bown, Matthew J and Jones, Gregory T and Harrison, Seamus C and Wright, Benjamin J and Bumpstead, Suzannah and Baas, Annette F and Gretarsdottir, Solveig and Badger, Stephen A and Bradley, Declan T and Burnand, Kevin and Child, Anne H and Clough, Rachel E and Cockerill, Gillian and Hafez, Hany and Scott, D. Julian A and Futers, Simon and Johnson, Anne and Sohrabi, Soroush and Smith, Alberto and Smith, Andrew J and Thompson, John R and Thompson, Matthew M and van Bockxmeer, Frank M and Waltham, Matthew and Matthiasson, Stefan E and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Blankensteijn, Jan D and Teijink, Joep A.W and Wijmenga, Cisca and de Graaf, Jacqueline and Kiemeney, Lambertus A and Assimes, Themistocles L and McPherson, Ruth and Folkersen, Lasse and Franco-Cereceda, Anders and Palmen, Jutta and Sylvius, Nicolas and Wild, John B and Refstrup, Mette and Edkins, Sarah and Gwilliam, Rhian and Hunt, Sarah E and Potter, Simon and Lindholt, Jes S and Frikke-Schmidt, Ruth and Tybjærg-Hansen, Anne and Hughes, Anne E and Golledge, Jonathan and Norman, Paul E and van Rij, Andre and Powell, Janet T and Eriksson, Per and Stefansson, Kari and Humphries, Steve E and Sayers, Robert D and Deloukas, Panos and Samani, Nilesh J and DIAGRAM Consortium and Global BPgen Consortium and VRCNZ Consortium and CARDIoGRAM Consortium
The American Journal of Human Genetics, ISSN 0002-9297, 11/2011, Volume 89, Issue 5, pp. 619 - 627
Abdominal aortic aneurysm (AAA) is a common cause of morbidity and mortality and has a significant heritability. We carried out a genome-wide association... 
SEQUENCE VARIANT | GELATINASE | METALLOPROTEINASE | DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | VASCULAR WALL | MUTATIONS | IDENTIFICATION | EXPRESSION | GENOME-WIDE ASSOCIATION | Data Interpretation, Statistical | Genetic Predisposition to Disease | Genome-Wide Association Study | Follow-Up Studies | Humans | Risk Factors | Genetic Loci - genetics | Male | Aortic Aneurysm, Abdominal - genetics | Aorta - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Organ Specificity | Case-Control Studies | Homozygote | Sterol Regulatory Element Binding Protein 1 - genetics | Cell Line, Tumor | Female | Aged | Polymorphism, Single Nucleotide | Odds Ratio
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Effect of short-term NSAID use on echocardiographic parameters in elderly people: a population-based cohort study
by van den Hondel, Karen Eline and Eijgelsheim, Mark and Ruiter, Rikje and Witteman, Jaqueline C M and Hofman, Albert and Stricker, Bruno H Ch
Heart, ISSN 1355-6037, 04/2011, Volume 97, Issue 7, pp. 540 - 543
BackgroundNon-steroidal anti-inflammatory drugs (NSAIDs) are associated with an increased risk of heart failure. NSAIDs inhibit the synthesis of renal... 
RISK | CARDIAC & CARDIOVASCULAR SYSTEMS | ROTTERDAM | CONGESTIVE-HEART-FAILURE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | Drug Administration Schedule | Follow-Up Studies | Humans | Middle Aged | Male | Ventricular Dysfunction, Left - chemically induced | Ventricular Dysfunction, Left - diagnostic imaging | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Ultrasonography | Aged, 80 and over | Female | Aged | Cohort Studies | Heart failure | Complications and side effects | Usage | Echocardiography | Development and progression | Dosage and administration | Nonsteroidal anti-inflammatory drugs | Research | Risk factors | Left ventricular function | Cardiovascular disease | Heart attacks | Health risk assessment | Older people
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Genetic variation in the fibrinogen-α and fibrinogen-γ genes in relation to arterial stiffness: the Rotterdam Study
by Sie, Mark PS and Isaacs, Aaron and de Maat, Moniek PM and Mattace-Raso, Francesco US and Uitterlinden, André G and Kardys, Isabella and Hofman, Albert and Hoeks, Arnold PG and Reneman, Robert S and van Duijn, Cornelia M and Witteman, Jaqueline CM
Journal of Hypertension, ISSN 0263-6352, 07/2009, Volume 27, Issue 7, pp. 1392 - 1398
OBJECTIVEArterial stiffness increases with age and predicts cardiovascular disease. Fibrinogen is an acute-phase protein and some studies showed an association... 
Fibrinogen-a and g | Pulse pressure | Pulse wave velocity | Arterial stiffness | Distensibility coefficient | arterial stiffness | C-REACTIVE PROTEIN | pulse pressure | fibrinogen-alpha and gamma | MYOCARDIAL-INFARCTION | LINKAGE PHASE | ATHEROSCLEROSIS | RISK | pulse wave velocity | distensibility coefficient | HYPERTENSIVE PATIENTS | BLOOD-PRESSURE | THR312ALA POLYMORPHISM | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | Genetic Variation | Haplotypes | Compliance | Arteries - physiopathology | Humans | Female | Genotype | Male | Aged | Polymorphism, Single Nucleotide | Fibrinogen - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights