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1. Full Text Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
by Lam, Wan L and Haase, Michael and Schübeler, Dirk and Davies, Jonathan J and Wittig, David and Weber, Michael and Oakeley, Edward J
Nature genetics, ISSN 1061-4036, 08/2005, Volume 37, Issue 8, pp. 853 - 862
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Transcription. Transcription factor. Splicing. Rna processing | Molecular genetics | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | Promoter Regions, Genetic | DNA Methylation | Humans | Cells, Cultured | CpG Islands | Female | Male | Chromosomes, Human | Reverse Transcriptase Polymerase Chain Reaction | Cell Line, Transformed | Physiological aspects | Genetic aspects | Promoters (Genetics) | Research | DNA damage | Cells | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
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2. Full Text High Resolution Clear Native Electrophoresis for In-gel Functional Assays and Fluorescence Studies of Membrane Protein Complexes
by Ilka Wittig and Michael Karas and Hermann Schägger
Molecular & cellular proteomics, ISSN 1535-9476, 07/2007, Volume 6, Issue 7, pp. 1215 - 1225
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Mitochondrial Proteins - analysis | Coloring Agents | Micelles | Electron Transport Complex I - analysis | Electron Transport Complex II - analysis | Electron Transport Complex III - analysis | Electron Transport Complex IV - analysis | Buffers | Detergents | Rosaniline Dyes | Electrophoresis, Polyacrylamide Gel - methods | Index Medicus
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3. Full Text Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans
by Krause-Kyora, Ben and Nutsua, Marcel and Boehme, Lisa and Pierini, Federica and Pedersen, Dorthe Dangvard and Kornell, Sabin-Christin and Drichel, Dmitriy and Bonazzi, Marion and Möbus, Lena and Tarp, Peter and Susat, Julian and Bosse, Esther and Willburger, Beatrix and Schmidt, Alexander H and Sauter, Jürgen and Franke, Andre and Wittig, Michael and Caliebe, Amke and Nothnagel, Michael and Schreiber, Stefan and Boldsen, Jesper L and Lenz, Tobias L and Nebel, Almut
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1569 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome, Bacterial | HLA-DRB1 Chains - genetics | Humans | Mycobacterium leprae - genetics | HLA-DQ beta-Chains - genetics | Fossils | DNA, Bacterial - genetics | High-Throughput Screening Assays | DNA, Ancient | Denmark | Leprosy - genetics | Haplotypes | Statistical analysis | Susceptibility | Health risks | Leprosy | Genomes | Population genetics | Risk factors | Hominids | Inflammatory diseases | White blood cells | Infectious diseases | Drb1 protein | Histocompatibility antigen HLA | Lesions | Deoxyribonucleic acid--DNA | Genotypes | Index Medicus
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4. Full Text Single base‐pair substitutions in exon–intron junctions of human genes: nature, distribution, and consequences for mRNA splicing
by Krawczak, Michael and Thomas, Nick S.T and Hundrieser, Bernd and Mort, Matthew and Wittig, Michael and Hampe, Jochen and Cooper, David N
Human mutation, ISSN 1059-7794, 02/2007, Volume 28, Issue 2, pp. 150 - 158
cryptic splice‐site | inherited disease | mRNA splicing | exon skipping | single nucleotide polymorphism | Single nucleotide polymorphism | Inherited disease | Exon skipping | Cryptic splice-site | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | RNA Splice Sites | Exons | Introns | Humans | Mutation, Missense | RNA, Messenger - metabolism | Point Mutation | Phenotype | DNA Mutational Analysis | RNA Splicing - genetics | Models, Genetic | Polymorphism, Single Nucleotide | Databases, Nucleic Acid | Neural Networks (Computer) | Index Medicus
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5. Full Text Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 ( IL17REL )
by Gieger, Christian and Vermeire, Séverine and Rosenstiel, Philip and Rutgeerts, Paul and Sina, Christian and Schreiber, Stefan and Anagnou, Nicholas P and Wichmann, H Erich and Sventoraityte, Jurgita and Mayr, Gabriele and Karlsen, Tom H and Buchert, Eva and Vatn, Morten H and Strachan, David and Mathew, Christopher G and Kupcinskas, Limas and McArdle, Wendy L and Krawczak, Michael and Albrecht, Mario and Onnie, Clive M and Wittig, Michael and Ellinghaus, David and Häsler, Robert and Gazouli, Maria and Balschun, Tobias and Franke, Andre and Nikolaus, Susanna and IBSEN Study Grp and IBSEN study group and and the IBSEN study group
Nature Genetics, ISSN 1061-4036, 04/2010, Volume 42, Issue 4, pp. 292 - 294
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Risk Factors | Colitis, Ulcerative - genetics | Chromosomes, Human, Pair 22 | Polymorphism, Single Nucleotide | Receptors, Interleukin-17 - genetics | Chromosomes, Human, Pair 7 | Quantitative trait loci | Genetic aspects | Research | Identification and classification | Ulcerative colitis | Inflammatory bowel disease | Health sciences | Genetics | Gene loci | Chromosomes | Index Medicus
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6. Full Text Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain
by Hardt, Stefanie and Heidler, Juliana and Albuquerque, Boris and Valek, Lucie and Altmann, Christine and Wilken-Schmitz, Annett and Schäfer, Michael K.E and Wittig, Ilka and Tegeder, Irmgard
Biochimica et biophysica acta. Molecular basis of disease, ISSN 0925-4439, 11/2017, Volume 1863, Issue 11, pp. 2727 - 2745
Progranulin | Pain | Proteomics | Solute carrier proteins | Nerve injury | Depression | Cognition | Anxiety | Explorative behavior | Zinc transporter | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neuralgia - genetics | Zinc - metabolism | Neuralgia - metabolism | Chronic Pain - genetics | Chronic Pain - psychology | Mice, Knockout | Peripheral Nerve Injuries - psychology | Carrier Proteins - genetics | Chronic Pain - metabolism | Animals | Carrier Proteins - metabolism | Peripheral Nerve Injuries - physiopathology | Peripheral Nerve Injuries - metabolism | Neuralgia - psychology | Ion Transport | Mice | Chronic Pain - physiopathology | Intercellular Signaling Peptides and Proteins - deficiency | Neuralgia - physiopathology | Peripheral Nerve Injuries - genetics | Psychological aspects | Medical research | Nervous system diseases | Care and treatment | Carrier proteins | Depression, Mental | Dietary supplements | Medicine, Experimental | Zinc in the body | Psychology, Pathological | Chronic pain | Index Medicus
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7. Full Text A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals
by Nebel, Almut and Kleindorp, Rabea and Caliebe, Amke and Nothnagel, Michael and Blanché, Hélène and Junge, Olaf and Wittig, Michael and Ellinghaus, David and Flachsbart, Friederike and Wichmann, Heinz-Erich and Meitinger, Thomas and Nikolaus, Susanna and Franke, Andre and Krawczak, Michael and Lathrop, Mark and Schreiber, Stefan
Mechanisms of ageing and development, ISSN 0047-6374, 2011, Volume 132, Issue 6, pp. 324 - 330
GWAS | Longevity | APOE | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Fundamental and applied biological sciences. Psychology | Development. Metamorphosis. Moult. Ageing | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Genome-Wide Association Study | Humans | Linkage Disequilibrium - genetics | Male | Genetic Loci | Longevity - genetics | Case-Control Studies | Apolipoproteins E - genetics | Alleles | Aged, 80 and over | Female | Polymorphism, Single Nucleotide | Germany | Analysis | Genomics | Genetic research | Disease susceptibility | Research | Universities and colleges | Apolipoproteins | Medical informatics | Apolipoprotein E | Linkage disequilibrium | Aging | Single-nucleotide polymorphism | Genetic factors | Regression analysis | Statistics | Survival | Age | Geriatrics | Index Medicus
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8. Full Text Maternal Epigenetic Pathways Control Parental Contributions to Arabidopsis Early Embryogenesis
by Autran, Daphné and Baroux, Célia and Raissig, Michael T and Lenormand, Thomas and Wittig, Michael and Grob, Stefan and Steimer, Andrea and Barann, Matthias and Klostermeier, Ulrich C and Leblanc, Olivier and Vielle-Calzada, Jean-Philippe and Rosenstiel, Phillip and Grimanelli, Daniel and Grossniklaus, Ueli
Cell (Cambridge), ISSN 0092-8674, 2011, Volume 145, Issue 5, pp. 707 - 719
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Epigenomics | Ovule - metabolism | Seeds - genetics | Transcriptional Activation | RNA Splicing Factors | Arabidopsis - embryology | Gene Expression Profiling | Genome, Plant | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Gene Expression Regulation, Developmental | Gene Expression Regulation, Plant | RNA, Small Interfering - metabolism | Arabidopsis thaliana | Embryonic development | Chromatin | RNA | Methylation | Genomics | Index Medicus | Seeds | Arabidopsis | Histone-Lysine N-Methyltransferase | Life Sciences | Arabidopsis Proteins | Ovule | RNA, Small Interfering | Development Biology
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