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Journal of the American College of Cardiology, ISSN 0735-1097, 09/2015, Volume 66, Issue 11, pp. 1236 - 1246
Journal Article
Journal Article
The New England journal of medicine, ISSN 1533-4406, 08/2019, Volume 381, Issue 6, pp. 531 - 542
This phase 3 trial showed that treatment with volanesorsen, an antisense oligonucleotide drug complementary to mRNA encoding apolipoprotein C-III, resulted in... 
Double-Blind Method | Oligonucleotides/administration & dosage | Thrombocytopenia/chemically induced | Humans | Middle Aged | RNA, Messenger/antagonists & inhibitors | Hyperlipoproteinemia Type I/blood | Male | Injections, Subcutaneous/adverse effects | Young Adult | Platelet Count | Analysis of Variance | Triglycerides/blood | Adult | Female | Aged | Apolipoprotein C-III/antagonists & inhibitors | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Apolipoprotein C-III - antagonists & inhibitors | Oligonucleotides - therapeutic use | Hyperlipoproteinemia Type I - blood | Apolipoprotein C-III - blood | Oligonucleotides - adverse effects | Apolipoprotein C-III - genetics | Injections, Subcutaneous - adverse effects | Thrombocytopenia - chemically induced | RNA, Messenger - antagonists & inhibitors | Triglycerides - blood | Hyperlipoproteinemia Type I - drug therapy | Oligonucleotides - administration & dosage | Usage | Safety and security measures | Genetic disorders | Chylomicrons | Drug therapy | Health aspects | Antilipemic agents | Thrombocytopenia | Fasting | Statistical analysis | Laboratories | Pancreatitis | Clinical trials | Antisense therapy | mRNA | Lipoprotein lipase | Injection | Lipase | Apolipoproteins | Fatty acids | Lipoproteins | Apolipoprotein C-III | Mutation | Platelets | Drug dosages | Pharmaceuticals | Index Medicus | Abridged Index Medicus | Life Sciences
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2011, Volume 58, Issue 16, pp. 1715 - 1727
Journal Article