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animals (17) 17
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1. Full Text Genome-wide association between DNA methylation and alternative splicing in an invertebrate
by Flores, Kevin and Wolschin, Florian and Corneveaux, Jason J and Allen, April N and Huentelman, Matthew J and Amdam, Gro V
BMC Genomics, ISSN 1471-2164, 09/2012, Volume 13, Issue 1, pp. 480 - 480
Background: Gene bodies are the most evolutionarily conserved targets of DNA methylation in eukaryotes. However, the regulatory functions of gene body DNA... 
METHYLOME | CONSERVATION | RNA-SEQ | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESOLUTION | HONEYBEE | TRANSCRIPTION | GENETICS & HEREDITY | PATTERNS | ARABIDOPSIS | DIVERGENCE | EXPRESSION | Genes, Insect | Genome-Wide Association Study | Alternative Splicing | Transcriptome | Molecular Sequence Data | Exons - genetics | Gene Expression Profiling | Wasps - genetics | DNA Methylation | Animals | Sequence Analysis, RNA | Base Sequence | Conserved Sequence | CpG Islands | Bees - genetics | Evolution, Molecular | Messenger RNA | Analysis | Physiological aspects | Genetic transcription | Research | Methylation | RNA splicing | Honeybee | Wildlife conservation | Genes | Genomics | Genomes | Bees | DNA | Genetic research | Genetic aspects | Wasps | Alternative splicing | Statistical analysis | Transcription | Exons | Conservation | DNA methylation | Data processing | Evolution | Evolutionary genetics | Homology | Gene expression
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2. Full Text Draft genome of the red harvester ant Pogonomyrmex barbatus
by Chris R. Smith and Christopher D. Smith and Hugh M. Robertson and Martin Helmkampf and Aleksey Zimin and Mark Yandell and Carson Holt and Hao Hu and Ehab Abouheif and Richard Benton and Elizabeth Cash and Vincent Croset and Cameron R. Currie and Eran Elhaik and Christine G. Elsik and Marie-Julie Favé and Vilaiwan Fernandes and Joshua D. Gibson and Dan Graur and Wulfila Gronenberg and Kirk J. Grubbs and Darren E. Hagen and Ana Sofia Ibarraran Viniegra and Brian R. Johnson and Reed M. Johnson and Abderrahman Khila and Jay W. Kim and Kaitlyn A. Mathis and Monica C. Munoz-Torres and Marguerite C. Murphy and Julie A. Mustard and Rin Nakamura and Oliver Niehuis and Surabhi Nigam and Rick P. Overson and Jennifer E. Placek and Rajendhran Rajakumar and Justin T. Reese and Garret Suen and Shu Tao and Candice W. Torres and Neil D. Tsutsui and Lumi Viljakainen and Florian Wolschin and Jürgen Gadau and Gene E. Robinson and Great Lakes Bioenergy Research Center (GLBRC)
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2011, Volume 108, Issue 14, pp. 5667 - 5672
We report the draft genome sequence of the red harvester ant, Pogonomyrmex barbatus. The genome was sequenced using 454 pyrosequencing, and the current... 
Social insects | Ants | Genes | Insect reproduction | Evolution | Genomes | Insect genomes | Methylation | Insect genetics | Insect castes | De novo genome | Genomic evolution | Social insect | Eusociality | Chemoreceptor | HYMENOPTERA | social insect | DIVERSIFICATION | DNA METHYLATION | DROSOPHILA-MELANOGASTER | MULTIDISCIPLINARY SCIENCES | genomic evolution | chemoreceptor | CHEMORECEPTOR SUPERFAMILY | EVOLUTION | GENES | eusociality | HONEYBEE APIS-MELLIFERA | de novo genome | INSIGHTS | Hierarchy, Social | Gene Regulatory Networks - genetics | Ants - genetics | Ants - physiology | Genome, Insect - genetics | Molecular Sequence Data | Phylogeny | North America | Sequence Analysis, DNA | Phenotype | Animals | Base Sequence | Receptors, Odorant - genetics | Polymorphism, Single Nucleotide - genetics | Desert Climate | Genomics - methods | Animal genetics | Genetic aspects | Research | Pogonomyrmex | Genotype & phenotype | Insects | Gene expression | Genomics | Biological Sciences
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3. Full Text Reversible switching between epigenetic states in honeybee behavioral subcastes
by Herb, Brian R and Wolschin, Florian and Hansen, Kasper D and Aryee, Martin J and Langmead, Ben and Irizarry, Rafael and Amdam, Gro V and Feinberg, Andrew P
Nature Neuroscience, ISSN 1097-6256, 10/2012, Volume 15, Issue 10, pp. 1371 - 1373
In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different... 
ENCODES | SYSTEM | DNA METHYLATION | MEMORY | GENE-EXPRESSION | NEUROSCIENCES | BRAIN | BEES | FAMILY | Phenotype | Animals | Epigenomics | Insect Proteins - physiology | Insect Proteins - genetics | Behavior, Animal - physiology | Bees - genetics | DNA Methylation - genetics | DNA Methylation - physiology | Physiological aspects | Epigenetic inheritance | Research | Methylation | DNA | Castes
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4. Full Text Deciphering Proteomic Signatures of Early Diapause in Nasonia
by Wolschin, Florian and Gadau, Jürgen
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 7, p. e6394
Insect diapause is an alternative life-history strategy used to increase longevity and survival in harsh environmental conditions. Even though some aspects of... 
BIOLOGY | Tandem Mass Spectrometry | Animals | Insect Proteins - chemistry | Proteomics | Chromatography, Liquid | Insecta - physiology | Life Cycle Stages | Proteins | Physiological aspects | Protein biosynthesis | Analysis | Larvae | Diapause | Switching theory | Biochemistry | Genomes | Pathways | Physiology | Life sciences | Biodegradation | Life history | Structural proteins | Glycerol | Abundance | Metabolism | Storage proteins | Environmental conditions | Studies | Molecular modelling | Insects | Protein synthesis | Invertebrates | Females | Heat shock
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5. Full Text Enrichment of phosphorylated proteins and peptides from complex mixtures using metal oxide/hydroxide affinity chromatography (MOAC)
by Wolschin, Florian and Wienkoop, Stefanie and Weckwerth, Wolfram
Proteomics, ISSN 1615-9853, 11/2005, Volume 5, Issue 17, pp. 4389 - 4397
A novel method termed metal oxide affinity chromatography (MOAC) of enriching for phosphorylated proteins and peptides based on the affinity of the phosphate... 
Beta-elimination | IMAC | Nano-ESI | Protein phosphorylation | MALDI | nano-ESI | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOPROTEOME | COLUMN | BIOCHEMICAL RESEARCH METHODS | protein phosphorylation | CHEMO-AFFINITY | IDENTIFICATION | MASS-SPECTROMETRY | PHOSPHOPEPTIDES | beta-elimination | SWITCHING HPLC ANALYSIS | SITES | BINDING | Glucose Oxidase - chemistry | Amino Acid Sequence | Phosphopeptides - chemistry | Hydroxides | Aluminum Hydroxide | Arabidopsis | Muramidase - chemistry | Metals | Plant Leaves | Molecular Sequence Data | Oxides | Pepsin A - chemistry | Phosphoproteins - chemistry | Peptide Fragments - chemistry | Arabidopsis Proteins - chemistry | Caseins - chemistry | Plant Proteins - chemistry | Reagent Kits, Diagnostic | Phosphoproteins - isolation & purification | Software | Ovalbumin - chemistry | Chromatography, Affinity - methods | Phosphopeptides - isolation & purification
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6. Full Text The Role of Methylation of DNA in Environmental Adaptation
by Kevin B. Flores and Florian Wolschin and Gro V. Amdam
Integrative and Comparative Biology, ISSN 1540-7063, 8/2013, Volume 53, Issue 2, pp. 359 - 372
Methylation of DNA is an epigenetic mechanism that influences patterns of gene expression. DNA methylation marks contribute to adaptive phenotypic variation... 
Ecological Epigenetics | ARABIDOPSIS-THALIANA | GENOME INSTABILITY | MEMORY FORMATION | ZOOLOGY | GERM-LINE | PROMOTER METHYLATION | GENE-EXPRESSION | MAMMALIAN DEVELOPMENT | DE-NOVO METHYLATION | EPIGENETIC MODIFICATION | MOUSE EMBRYO | Genetic Variation | Base Sequence - genetics | Phenotype | Animals | Adaptation, Physiological - genetics | Genome, Insect - genetics | Environment | Bees - genetics | DNA Methylation - genetics | Mutation - genetics | Bees - physiology | Evolution, Molecular | Usage | DNA | Analysis | Cytosine | Methylation | Gene expression | Testing | Genotype & phenotype | Animal behavior | Epigenetics | DNA methylation | Mutation | Bees
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7. Full Text Integration of Metabolomic and Proteomic Phenotypes
by Stefanie Wienkoop and Katja Morgenthal and Florian Wolschin and Matthias Scholz and Joachim Selbig and Wolfram Weckwerth
Molecular & Cellular Proteomics, ISSN 1535-9476, 09/2008, Volume 7, Issue 9, pp. 1725 - 1736
Statistical mining and integration of complex molecular data including metabolites, proteins, and transcripts is one of the critical goals of systems biology... 
ARABIDOPSIS-THALIANA | PATTERN-RECOGNITION | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | LOW-TEMPERATURE | RNA-BINDING PROTEIN | INDEPENDENT COMPONENT ANALYSIS | QUANTITATIVE SHOTGUN PROTEOMICS | COLD RESPONSE PATHWAY | PRE-MESSENGER-RNA | FREEZING TOLERANCE
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8. Full Text Integration of metabolomic and proteomic phenoptypes
by Wienkoop, Stefanie and Morgenthal, Katja and Wolschin, Florian and Scholz, Matthias and Selbig, Joachim and Weckwerth, Wolfram
Molecular and Cellular Proteomics, ISSN 1535-9476, 09/2008, Volume 7, Issue 9, pp. 1725 - 1736
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9. Full Text Differential gene expression and protein abundance evince ontogenetic bias toward castes in a primitively eusocial wasp
by Hunt, James H and Wolschin, Florian and Henshaw, Michael T and Newman, Thomas C and Toth, Amy L and Amdam, Gro V
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, p. e10674
Polistes paper wasps are models for understanding conditions that may have characterized the origin of worker and queen castes and, therefore, the origin of... 
POLISTES-METRICUS | FLESH FLY | PAPER WASP | APIS-MELLIFERA | MULTIDISCIPLINARY SCIENCES | DIVISION-OF-LABOR | SOCIAL WASPS | SARCOPHAGA-CRASSIPALPIS | HONEY-BEE | PUPAL DIAPAUSE | MOSQUITO CULEX-PIPIENS | Genes, Insect - genetics | Bias | RNA, Messenger - genetics | Gene Expression Regulation | Peptides - genetics | Insect Proteins - genetics | Gene Expression Profiling | Social Dominance | RNA, Messenger - metabolism | Wasps - genetics | Discriminant Analysis | Animals | Peptides - metabolism | Sex Determination Processes | Mass Spectrometry | Chromatography, Liquid | Larva - genetics | Insect Proteins - metabolism | Proteins | Honeybee | Analysis | Genes | Physiological aspects | Wasps | Gene expression | Bees | Larvae | Divergence | Peptides | Diapause | Biology | Ontogeny | Expressed sequence tags | Caste determination | Morphogenesis | Signal transduction | Evolution | Physiology | Life sciences | Abundance | Castes | Metabolism | Insulin | Storage proteins | Honey | Signaling | Hypotheses | Insects | Animal behavior | Morphology | Proteomics | Regulatory mechanisms (biology) | Workers (insect caste) | Adults | Females
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10. Full Text Age-related learning deficits can be reversible in honeybees Apis mellifera
by Baker, Nicholas and Wolschin, Florian and Amdam, Gro V
Experimental Gerontology, ISSN 0531-5565, 10/2012, Volume 47, Issue 10, pp. 764 - 772
Many animals are characterized by declining brain function at advanced ages, including honeybees ( ). Variation in honeybee social development, moreover,... 
Peroxiredoxin | Recovery-related plasticity | Pavlovian learning | LC–MS2 proteomics | Cytochrome P450 | Brain senescence | Heat shock protein 8 | LC-MS | proteomics | LIFE-SPAN | OXIDATIVE STRESS | SOCIAL-ROLE | HUMAN BRAIN | ALZHEIMERS-DISEASE | GERIATRICS & GERONTOLOGY | LC-MS2 proteomics | GLUTAMATE TRANSPORTER | CENTRAL-NERVOUS-SYSTEM | BEE WORKERS | SUPEROXIDE-DISMUTASE | PLASTICITY | Smell - physiology | Taste Perception - physiology | Animals | Aging - physiology | Analysis of Variance | Conditioning (Psychology) - physiology | Recovery of Function - physiology | Behavior, Animal - physiology | Proteome | Brain Chemistry | Bees - physiology | Discrimination Learning - physiology | Phosphates | Enzymes | Brain | Honeybee | Nurses | Analysis | Heat shock proteins | Liquid chromatography | Mass spectrometry | Bees
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11. Full Text The worker honeybee fat body proteome is extensively remodeled preceding a major life-history transition
by Chan, Queenie W.T and Mutti, Navdeep S and Foster, Leonard J and Kocher, Sarah D and Amdam, Gro V and Wolschin, Florian
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24794
Honeybee workers are essentially sterile female helpers that make up the majority of individuals in a colony. Workers display a marked change in physiology... 
QUANTITATIVE MASS-SPECTROMETRY | VITELLOGENIN | COLONY-LEVEL SELECTION | GLUCOSE-HOMEOSTASIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | DIVISION-OF-LABOR | BEE APIS-MELLIFERA | JUVENILE-HORMONE | INSULIN-RECEPTOR SUBSTRATE-1 | BEHAVIORAL-DEVELOPMENT | Down-Regulation | Gene Expression Regulation | Genotype | Lipid Metabolism | Proteome | RNA, Messenger - metabolism | Bees - physiology | Insulin - metabolism | Lipids - chemistry | Phenotype | Animals | Carbohydrates - chemistry | RNA Interference | Abdomen - physiology | Glucose - metabolism | Female | Bees - genetics | Models, Genetic | RNA, Double-Stranded - metabolism | Proteomics - methods | Physiological aspects | Honeybee | Bees | Innovations | Brain | Homeostasis | Lipids | Biochemistry | Food science | Proteins | Physiology | Life sciences | Lipid metabolism | Fat body | Genotypes | Age | Carbohydrates | Life history | RNA-mediated interference | Phenotypic plasticity | Carbohydrate metabolism | Thorax | Metabolism | Gene expression | Ribonucleic acid--RNA | Insulin | Foraging behavior | Forages | Abdomen | Signaling | Proteomics | Hypopharyngeal gland | Workers (insect caste) | Scientific imaging | Molecular biology | Mass spectrometry | RNA | Ribonucleic acid
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12. Full Text A mass spectrometry-based approach to host cell protein identification and its application in a comparability exercise
by Reisinger, Veronika and Toll, Hansjoerg and Mayer, Robert Ernst and Visser, Jan and Wolschin, Florian
Analytical Biochemistry, ISSN 0003-2697, 10/2014, Volume 463, pp. 1 - 6
Host cell proteins (HCPs) are process-related impurities present in biopharmaceuticals and are generally considered to be critical quality attributes. Changes... 
Comparability | HCP | Mass spectrometry | Biopharmaceutical | CHEMISTRY, ANALYTICAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUANTITATION | BIOCHEMICAL RESEARCH METHODS | BIOTHERAPEUTICS | IMPURITIES | BIOPHARMACEUTICALS | DYNAMICS | CAPTURE | Tandem Mass Spectrometry | Molecular Weight | Proteins - metabolism | S100 Proteins - metabolism | Proteins - analysis | Chromatography, High Pressure Liquid | Chemistry Techniques, Analytical - methods | Pharmaceutical Preparations - analysis | Trypsin - metabolism | S100 Proteins - analysis | Proteins | Biological products | Enzyme-linked immunosorbent assay
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13. Full Text A Diapause Pathway Underlies the Gyne Phenotype in Polistes Wasps, Revealing an Evolutionary Route to Caste-Containing Insect Societies
by James H. Hunt and Bart J. Kensinger and Jessica A. Kossuth and Michael T. Henshaw and Kari Norberg and Florian Wolschin and Gro V. Amdam
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2007, Volume 104, Issue 35, pp. 14020 - 14025
Colonies of social wasps, ants, and bees are characterized by the production of two phenotypes of female offspring, workers that remain at their natal nest and... 
Social insects | Pupae | Phenotypes | Insect larvae | Diapause | Female animals | Larval development | Storage proteins | Insect castes | Cocoons | Hexameric storage proteins | Social behavior | Caste development | Life-history pleiotropy | Juvenile hormone | HYMENOPTERA | PAPER WASP | caste development | DROSOPHILA-MELANOGASTER | social behavior | MULTIDISCIPLINARY SCIENCES | SOCIAL WASPS | METRICUS | MASS-SPECTROMETRY | EUSOCIALITY | VESPIDAE | life-history pleiotropy | LIFE-HISTORY | juvenile hormone | JUVENILE-HORMONE | hexameric storage proteins | Biological Evolution | Phenotype | Reproduction | Animals | Species Specificity | Social Behavior | Ants - physiology | Hemolymph | Female | Wasps - genetics | Bees - physiology | Evaluation | Influence | Wasps | Behavior | Social behavior in animals | Insect societies | Natural history | Proteins | Genotype & phenotype | Genetics | Hormones | Insects | Biological Sciences
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