PLoS Pathogens, ISSN 1553-7366, 01/2011, Volume 7, Issue 1, p. e1001264
Bacterial extracellular polysaccharides are a key constituent of the extracellular matrix material of biofilms. Pseudomonas aeruginosa is a model organism for...
SYSTEM | RECOMBINATION | VARIANTS | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | BACTERIAL BIOFILMS | CYCLIC-DI-GMP | TOBRAMYCIN | VIROLOGY | EXOPOLYSACCHARIDE PRODUCTION | SWARMING MOTILITY | MODULATION | PARASITOLOGY | Microbial Viability - drug effects | Pseudomonas aeruginosa - growth & development | Tobramycin - pharmacology | Bacterial Proteins - genetics | Biofilms - growth & development | Polysaccharides, Bacterial - metabolism | Pseudomonas aeruginosa - physiology | Alginates | Pseudomonas aeruginosa - drug effects | Bacterial Adhesion | Microbial Sensitivity Tests | Polysaccharides, Bacterial - genetics | Extracellular Matrix - physiology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Gene Expression Regulation, Bacterial | Physiological aspects | Pseudomonas aeruginosa | Operons | Genetic aspects | Research | Microbial mats | Microbial polysaccharides | Antimicrobial agents | Biofilms | Microbiology | Experiments | Bacteriology
SYSTEM | RECOMBINATION | VARIANTS | ANTIBIOTIC-RESISTANCE | MICROBIOLOGY | BACTERIAL BIOFILMS | CYCLIC-DI-GMP | TOBRAMYCIN | VIROLOGY | EXOPOLYSACCHARIDE PRODUCTION | SWARMING MOTILITY | MODULATION | PARASITOLOGY | Microbial Viability - drug effects | Pseudomonas aeruginosa - growth & development | Tobramycin - pharmacology | Bacterial Proteins - genetics | Biofilms - growth & development | Polysaccharides, Bacterial - metabolism | Pseudomonas aeruginosa - physiology | Alginates | Pseudomonas aeruginosa - drug effects | Bacterial Adhesion | Microbial Sensitivity Tests | Polysaccharides, Bacterial - genetics | Extracellular Matrix - physiology | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Gene Expression Regulation, Bacterial | Physiological aspects | Pseudomonas aeruginosa | Operons | Genetic aspects | Research | Microbial mats | Microbial polysaccharides | Antimicrobial agents | Biofilms | Microbiology | Experiments | Bacteriology
Journal Article
Journal of the American Heart Association, ISSN 2047-9980, 10/2016, Volume 5, Issue 10, p. n/a
Background The extent to which angina is associated with future cardiovascular events in patients with coronary artery disease has long been debated. Methods...
cardiovascular events | coronary artery disease | angina | Cardiovascular events | Coronary artery disease | Angina | CARDIAC & CARDIOVASCULAR SYSTEMS | OUTPATIENTS | MYOCARDIAL-ISCHEMIA | RISK | SYMPTOMS | RATES | HEART-DISEASE | SOUL | PECTORIS | CLARIFY REGISTRY | CLINICAL-OUTCOMES | United States - epidemiology | Myocardial Infarction - epidemiology | Prognosis | Humans | Middle Aged | Proportional Hazards Models | Hospitalization - statistics & numerical data | Male | Case-Control Studies | Myocardial Revascularization - utilization | Angina, Stable - epidemiology | Cardiovascular Diseases - mortality | Female | Registries | Stroke - epidemiology | Aged | Coronary Artery Disease - epidemiology | Odds Ratio | Heart Failure - epidemiology
cardiovascular events | coronary artery disease | angina | Cardiovascular events | Coronary artery disease | Angina | CARDIAC & CARDIOVASCULAR SYSTEMS | OUTPATIENTS | MYOCARDIAL-ISCHEMIA | RISK | SYMPTOMS | RATES | HEART-DISEASE | SOUL | PECTORIS | CLARIFY REGISTRY | CLINICAL-OUTCOMES | United States - epidemiology | Myocardial Infarction - epidemiology | Prognosis | Humans | Middle Aged | Proportional Hazards Models | Hospitalization - statistics & numerical data | Male | Case-Control Studies | Myocardial Revascularization - utilization | Angina, Stable - epidemiology | Cardiovascular Diseases - mortality | Female | Registries | Stroke - epidemiology | Aged | Coronary Artery Disease - epidemiology | Odds Ratio | Heart Failure - epidemiology
Journal Article
2014, 1, ISBN 0520283619, xiv, 294 pages
While many books examine specific wars, few study the history of war worldwide and from an evolutionary perspective. A Global History of War is one of the...
Strategy | War | History | War and civilization | Military
Strategy | War | History | War and civilization | Military
Book
Nature Reviews Microbiology, ISSN 1740-1526, 05/2015, Volume 13, Issue 5, pp. 255 - 268
Nearly all bacteria form biofilms as a strategy for survival and persistence. Biofilms are associated with biotic and abiotic surfaces and are composed of...
TRANSCRIPTIONAL REGULATOR | INTESTINAL COLONIZATION | OUTER-MEMBRANE VESICLES | PSEUDOMONAS-AERUGINOSA | STRINGENT RESPONSE | AMP RECEPTOR PROTEIN | RUGOSE COLONY MORPHOLOGY | MICROBIOLOGY | CYCLIC DI-GMP | O1 EL-TOR | VPS BIOSYNTHESIS GENES | Vibrio cholerae - physiology | Signal Transduction - physiology | Environmental Microbiology | Bacterial Adhesion - physiology | Biofilms - growth & development | Microbiological research | Research | Microbial mats | Growth | Vibrio cholerae | Cell adhesion
TRANSCRIPTIONAL REGULATOR | INTESTINAL COLONIZATION | OUTER-MEMBRANE VESICLES | PSEUDOMONAS-AERUGINOSA | STRINGENT RESPONSE | AMP RECEPTOR PROTEIN | RUGOSE COLONY MORPHOLOGY | MICROBIOLOGY | CYCLIC DI-GMP | O1 EL-TOR | VPS BIOSYNTHESIS GENES | Vibrio cholerae - physiology | Signal Transduction - physiology | Environmental Microbiology | Bacterial Adhesion - physiology | Biofilms - growth & development | Microbiological research | Research | Microbial mats | Growth | Vibrio cholerae | Cell adhesion
Journal Article
5.
Full Text
Flagella and Pili-Mediated Near-Surface Single-Cell Motility Mechanisms in P. aeruginosa
Biophysical Journal, ISSN 0006-3495, 04/2011, Volume 100, Issue 7, pp. 1608 - 1616
Bacterial biofilms are structured multicellular communities that are responsible for a broad range of infections. Knowing how free-swimming bacteria adapt...
MYXOCOCCUS-XANTHUS | BIOPHYSICS | TWITCHING MOTILITY | PSEUDOMONAS-AERUGINOSA | ESCHERICHIA-COLI | MULTICELLULAR STRUCTURES | SWARMING MOTILITY | IV PILI | ROTARY MOTOR | BACTERIAL BIOFILMS | BIOFILM FORMATION | Biofilms | Flagella - metabolism | Movement | Pseudomonas aeruginosa - metabolism | Cell Division | Cell Membrane - metabolism | Pseudomonas aeruginosa - cytology | Fimbriae, Bacterial - metabolism | Biological Systems and Multicellular Dynamics
MYXOCOCCUS-XANTHUS | BIOPHYSICS | TWITCHING MOTILITY | PSEUDOMONAS-AERUGINOSA | ESCHERICHIA-COLI | MULTICELLULAR STRUCTURES | SWARMING MOTILITY | IV PILI | ROTARY MOTOR | BACTERIAL BIOFILMS | BIOFILM FORMATION | Biofilms | Flagella - metabolism | Movement | Pseudomonas aeruginosa - metabolism | Cell Division | Cell Membrane - metabolism | Pseudomonas aeruginosa - cytology | Fimbriae, Bacterial - metabolism | Biological Systems and Multicellular Dynamics
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2018, Volume 114, Issue 3, pp. 28a - 28a
Journal Article
Trends in Microbiology, ISSN 0966-842X, 2015, Volume 23, Issue 12, pp. 775 - 788
The bacterial type IV pilus (T4P) is a versatile molecular machine with a broad range of functions. Recent advances revealed that the molecular components and...
Internal Medicine | molecular machine | EPS | molecular force | twitching motility | Twitching motility | Molecular machine | Molecular force | TWITCHING MOTILITY | TUG-OF-WAR | SOCIAL MOTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PSEUDOMONAS-AERUGINOSA PSL | FLAGELLA | NEISSERIA-GONORRHOEAE | MICROBIOLOGY | DEVELOPMENTAL BIOLOGY | GLIDING MOTILITY | RETRACTION | BIOFILM FORMATION | Fimbriae Proteins - metabolism | Elasticity | Fimbriae, Bacterial - chemistry | Models, Molecular | Bacterial Physiological Phenomena | Fimbriae, Bacterial - ultrastructure | Pseudomonas aeruginosa - physiology | Fimbriae Proteins - physiology | Biomechanical Phenomena | Bacterial Adhesion - physiology | Fimbriae, Bacterial - physiology | Pseudomonas aeruginosa - metabolism | Fimbriae Proteins - ultrastructure | Bacteria - cytology | Fimbriae Proteins - chemistry | Mutation | Locomotion - physiology | Evolution, Molecular | Fimbriae, Bacterial - metabolism | Bacteria
Internal Medicine | molecular machine | EPS | molecular force | twitching motility | Twitching motility | Molecular machine | Molecular force | TWITCHING MOTILITY | TUG-OF-WAR | SOCIAL MOTILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PSEUDOMONAS-AERUGINOSA PSL | FLAGELLA | NEISSERIA-GONORRHOEAE | MICROBIOLOGY | DEVELOPMENTAL BIOLOGY | GLIDING MOTILITY | RETRACTION | BIOFILM FORMATION | Fimbriae Proteins - metabolism | Elasticity | Fimbriae, Bacterial - chemistry | Models, Molecular | Bacterial Physiological Phenomena | Fimbriae, Bacterial - ultrastructure | Pseudomonas aeruginosa - physiology | Fimbriae Proteins - physiology | Biomechanical Phenomena | Bacterial Adhesion - physiology | Fimbriae, Bacterial - physiology | Pseudomonas aeruginosa - metabolism | Fimbriae Proteins - ultrastructure | Bacteria - cytology | Fimbriae Proteins - chemistry | Mutation | Locomotion - physiology | Evolution, Molecular | Fimbriae, Bacterial - metabolism | Bacteria
Journal Article
8.
Full Text
Psl trails guide exploration and microcolony formation in Pseudomonas aeruginosa biofilms
Nature, ISSN 0028-0836, 05/2013, Volume 497, Issue 7449, pp. 388 - 391
Bacterial biofilms are surface-associated, multicellular, morphologically complex microbial communities(1-7). Biofilm-forming bacteria such as the...
EXOPOLYSACCHARIDE | MATRIX | ADHESION | INFECTIONS | POWER LAWS | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | IV PILI | CYSTIC-FIBROSIS | BACTERIAL BIOFILMS | POLYSACCHARIDE | Feedback, Physiological | Algorithms | Bacterial Adhesion - physiology | Pseudomonas aeruginosa - growth & development | Staining and Labeling | Biofilms - growth & development | Polysaccharides, Bacterial - metabolism | Fluorescent Dyes | Pseudomonas aeruginosa - cytology | Cell Tracking | Physiological aspects | Polysaccharides | Research | Microbial mats | Properties | Cellular control mechanisms | Immunization | Motility | Microbiology | Bacteria | Experiments | Bacteriology
EXOPOLYSACCHARIDE | MATRIX | ADHESION | INFECTIONS | POWER LAWS | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | IV PILI | CYSTIC-FIBROSIS | BACTERIAL BIOFILMS | POLYSACCHARIDE | Feedback, Physiological | Algorithms | Bacterial Adhesion - physiology | Pseudomonas aeruginosa - growth & development | Staining and Labeling | Biofilms - growth & development | Polysaccharides, Bacterial - metabolism | Fluorescent Dyes | Pseudomonas aeruginosa - cytology | Cell Tracking | Physiological aspects | Polysaccharides | Research | Microbial mats | Properties | Cellular control mechanisms | Immunization | Motility | Microbiology | Bacteria | Experiments | Bacteriology
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2009, Volume 48, Issue 35, pp. 6494 - 6498
Aptamer advantages: Cell‐specific delivery of the anticancer drug cisplatin through a nucleolin‐aptamer‐conjugated, cisplatin‐encapsulating liposome delivery...
drug delivery | cisplatin | liposomes | aptamers | Drug delivery | Liposomes | Cisplatin | Aptamers | ANTI-HER2 IMMUNOLIPOSOMES | SYSTEMATIC EVOLUTION | ANTIPROLIFERATIVE ACTIVITY | TUMOR-CELLS | PLGA-PEG NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | MACROMOLECULAR THERAPEUTICS | BREAST-CANCER CELLS | MOLECULAR RECOGNITION | IN-VIVO | EXPONENTIAL ENRICHMENT | Cell Survival - drug effects | Liposomes - chemistry | Humans | Aptamers, Nucleotide - chemistry | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Antineoplastic Agents - administration & dosage | Cisplatin - pharmacology | Cisplatin - administration & dosage
drug delivery | cisplatin | liposomes | aptamers | Drug delivery | Liposomes | Cisplatin | Aptamers | ANTI-HER2 IMMUNOLIPOSOMES | SYSTEMATIC EVOLUTION | ANTIPROLIFERATIVE ACTIVITY | TUMOR-CELLS | PLGA-PEG NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | MACROMOLECULAR THERAPEUTICS | BREAST-CANCER CELLS | MOLECULAR RECOGNITION | IN-VIVO | EXPONENTIAL ENRICHMENT | Cell Survival - drug effects | Liposomes - chemistry | Humans | Aptamers, Nucleotide - chemistry | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Antineoplastic Agents - administration & dosage | Cisplatin - pharmacology | Cisplatin - administration & dosage
Journal Article
PLoS Pathogens, ISSN 1553-7366, 06/2016, Volume 12, Issue 6, p. e1005705
Triggering antimicrobial mechanisms inmacrophages infected with intracellular pathogens, such as mycobacteria, is critical to host defense against the...
PROTEIN S100A12 | CALGRANULIN C | DENDRITIC CELLS | MEMBRANE | TUBERCULOSIS INFECTION | RECEPTOR | MICROBIOLOGY | VIROLOGY | EN-RAGE | MOLECULAR-CLONING | PSORIATIC SKIN | EXPRESSION | PARASITOLOGY | S100A12 Protein - immunology | Humans | Mycobacterium tuberculosis - immunology | Transcriptome | Gene Expression Profiling | Leprosy - immunology | Mycobacterium Infections - immunology | Mycobacterium leprae - immunology | Flow Cytometry | Fluorescent Antibody Technique | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Macrophages - microbiology | Infection | RNA sequencing | RNA | Analysis | Genes | Leprosy | Macrophages | Gene expression | Health aspects | Mycobacterium | Usage | Mycobacteria | Antimicrobial peptides | Research | Flow cytometry | Laboratories | Funding | Genomics | Antimicrobial agents | Defense mechanisms | Infections | Defense | Infectious diseases | Spectrum analysis | Rodents | Immune system
PROTEIN S100A12 | CALGRANULIN C | DENDRITIC CELLS | MEMBRANE | TUBERCULOSIS INFECTION | RECEPTOR | MICROBIOLOGY | VIROLOGY | EN-RAGE | MOLECULAR-CLONING | PSORIATIC SKIN | EXPRESSION | PARASITOLOGY | S100A12 Protein - immunology | Humans | Mycobacterium tuberculosis - immunology | Transcriptome | Gene Expression Profiling | Leprosy - immunology | Mycobacterium Infections - immunology | Mycobacterium leprae - immunology | Flow Cytometry | Fluorescent Antibody Technique | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Macrophages - microbiology | Infection | RNA sequencing | RNA | Analysis | Genes | Leprosy | Macrophages | Gene expression | Health aspects | Mycobacterium | Usage | Mycobacteria | Antimicrobial peptides | Research | Flow cytometry | Laboratories | Funding | Genomics | Antimicrobial agents | Defense mechanisms | Infections | Defense | Infectious diseases | Spectrum analysis | Rodents | Immune system
Journal Article
Science, ISSN 0036-8075, 10/2010, Volume 330, Issue 6001, pp. 197 - 197
Bacterial biofilms are structured multicellular communities involved in a broad range of infections. Knowing how free-swimming bacteria adapt their motility...
Bioengineering | Walking | Biofilms | Bacteria | Materials science | Trajectories | BREVIA | MULTIDISCIPLINARY SCIENCES | BIOFILM FORMATION | MOTILITY | Movement | Pseudomonas aeruginosa - physiology | Bacterial Adhesion | Algorithms | Microscopy | Pseudomonas aeruginosa - genetics | Fimbriae, Bacterial - physiology | Cell Division | Mutation | Pseudomonas aeruginosa - ultrastructure | Databases, Factual | Motion Pictures | Genotype & phenotype | Morphology | Communities | Strategy | Exploration | Vertical orientation | Forages
Bioengineering | Walking | Biofilms | Bacteria | Materials science | Trajectories | BREVIA | MULTIDISCIPLINARY SCIENCES | BIOFILM FORMATION | MOTILITY | Movement | Pseudomonas aeruginosa - physiology | Bacterial Adhesion | Algorithms | Microscopy | Pseudomonas aeruginosa - genetics | Fimbriae, Bacterial - physiology | Cell Division | Mutation | Pseudomonas aeruginosa - ultrastructure | Databases, Factual | Motion Pictures | Genotype & phenotype | Morphology | Communities | Strategy | Exploration | Vertical orientation | Forages
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 4032 - 13
Under homeostatic conditions the release of self-RNA from dying cells does not promote inflammation. However, following injury or inflammatory skin diseases...
PLASMACYTOID DENDRITIC CELLS | ADAPTIVE IMMUNITY | DEFENSE | DOUBLE-STRANDED-RNA | ACTIVATION | INTERFERON | MULTIDISCIPLINARY SCIENCES | ANTIMICROBIAL PEPTIDE LL-37 | INNATE | KERATINOCYTES | SKIN | Clathrin | Psoriasis | Keratinocytes | Inflammation | Pattern recognition | Macrophages | Ribonucleic acid--RNA | Immunological tolerance | Cell surface | Interleukin 6 | Endocytosis | Scavenger receptors | Skin diseases | Interferon | Non-coding RNA | Rosacea
PLASMACYTOID DENDRITIC CELLS | ADAPTIVE IMMUNITY | DEFENSE | DOUBLE-STRANDED-RNA | ACTIVATION | INTERFERON | MULTIDISCIPLINARY SCIENCES | ANTIMICROBIAL PEPTIDE LL-37 | INNATE | KERATINOCYTES | SKIN | Clathrin | Psoriasis | Keratinocytes | Inflammation | Pattern recognition | Macrophages | Ribonucleic acid--RNA | Immunological tolerance | Cell surface | Interleukin 6 | Endocytosis | Scavenger receptors | Skin diseases | Interferon | Non-coding RNA | Rosacea
Journal Article