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Gut, ISSN 0017-5749, 08/2017, Volume 66, Issue 8, pp. 1496 - 1506
ObjectiveWe investigated the mutational landscape of mammalian target of rapamycin (mTOR) signalling cascade in hepatocellular carcinomas (HCCs) with chronic... 
HEPATITIS B | GENE MUTATION | MUTATION SCREENING | HEPATOCELLULAR CARCINOMA | THERAPEUTIC TARGETS | HEPATOCELLULAR-CARCINOMA | MTORC1 | MICE | GASTROENTEROLOGY & HEPATOLOGY | PATHWAY | Neoplasm Transplantation | Antibiotics, Antineoplastic - pharmacology | Axin Protein - genetics | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Male | Liver Neoplasms - chemistry | Tumor Suppressor Protein p53 - genetics | Young Adult | DNA Mutational Analysis | Carcinoma, Hepatocellular - genetics | Tumor Suppressor Proteins - genetics | Adult | Female | Carcinoma, Hepatocellular - chemistry | Nuclear Proteins - genetics | Tumor Stem Cell Assay | Cell Proliferation - genetics | Sirolimus - therapeutic use | Liver Neoplasms - genetics | Signal Transduction | Mutation Rate | Transcription Factors - genetics | Sirolimus - pharmacology | beta Catenin - genetics | Animals | Antibiotics, Antineoplastic - therapeutic use | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Mice | Carcinoma, Hepatocellular - metabolism | Tumor Suppressor Proteins - analysis | Reports | Care and treatment | Hepatoma | Research | Gene mutations | TOR protein | Immunohistochemistry | Tuberous Sclerosis Complex 2 | Hepatocellular carcinoma | Infections | Genomes | Insulin-like growth factors | Kinases | Cancer therapies | Tuberous Sclerosis Complex 1 | Liver cancer | Signal transduction | Epidermal growth factor | Next-generation sequencing | Gastroenterology | Xenografts | Aggressive behavior | Colonies | Hypersensitivity | Tuberous sclerosis | Rapamycin | FDA approval | Patients | Ligands | Mutation | Tumors | 1506 | Hepatology
Journal Article
by Jacobs, Kevin B and Yeager, Meredith and Zhou, Weiyin and Wacholder, Sholom and Wang, Zhaoming and Rodriguez-Santiago, Benjamin and Hutchinson, Amy and Deng, Xiang and Liu, Chenwei and Horner, Marie-Josephe and Cullen, Michael and Epstein, Caroline G and Burdett, Laurie and Dean, Michael C and Chatterjee, Nilanjan and Sampson, Joshua and Chung, Charles C and Kovaks, Joseph and Gapstur, Susan M and Stevens, Victoria L and Teras, Lauren T and Gaudet, Mia M and Albanes, Demetrius and Weinstein, Stephanie J and Virtamo, Jarmo and Taylor, Philip R and Freedman, Neal D and Abnet, Christian C and Goldstein, Alisa M and Hu, Nan and Yu, Kai and Yuan, Jian-Min and Liao, Linda and Ding, Ti and Qiao, You-Lin and Gao, Yu-Tang and Koh, Woon-Puay and Xiang, Yong-Bing and Tang, Ze-Zhong and Fan, Jin-Hu and Aldrich, Melinda C and Amos, Christopher and Blot, William J and Bock, Cathryn H and Gillanders, Elizabeth M and Harris, Curtis C and Haiman, Christopher A and Henderson, Brian E and Kolonel, Laurence N and Le Marchand, Loic and McNeill, Lorna H and Rybicki, Benjamin A and Schwartz, Ann G and Signorello, Lisa B and Spitz, Margaret R and Wiencke, John K and Wrensch, Margaret and Wu, Xifeng and Zanetti, Krista A and Ziegler, Regina G and Figueroa, Jonine D and Garcia-Closas, Montserrat and Malats, Nuria and Marenne, Gaelle and Prokunina-Olsson, Ludmila and Baris, Dalsu and Schwenn, Molly and Johnson, Alison and Landi, Maria Teresa and Goldin, Lynn and Consonni, Dario and Bertazzi, Pier Alberto and Rotunno, Melissa and Rajaraman, Preetha and Andersson, Ulrika and Freeman, Laura E Beane and Berg, Christine D and Buring, Julie E and Butler, Mary A and Carreon, Tania and Feychting, Maria and Ahlbom, Anders and Gaziano, J Michael and Giles, Graham G and Hallmans, Goran and Hankinson, Susan E and Hartge, Patricia and Henriksson, Roger and Inskip, Peter D and Johansen, Christoffer and Landgren, Annelie and McKean-Cowdin, Roberta and Michaud, Dominique S and Melin, Beatrice S and Peters, Ulrike and Ruder, Avima M and Sesso, Howard D and Severi, Gianluca and Shu, Xiao-Ou and Visvanathan, Kala and ...
Nature genetics, ISSN 1546-1718, 2012, Volume 44, Issue 6, pp. 651 - 658
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The New England journal of medicine, ISSN 1533-4406, 2019, Volume 380, Issue 24, pp. 2295 - 2306
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by Tragante, Vinicius and Barnes, Michael R and Ganesh, Santhi K and Lanktree, Matthew B and Guo, Wei and Franceschini, Nora and Smith, Erin N and Johnson, Toby and Holmes, Michael V and Padmanabhan, Sandosh and Karczewski, Konrad J and Almoguera, Berta and Barnard, John and Baumert, Jens and Chang, Yen-Pei Christy and Elbers, Clara C and Farrall, Martin and Fischer, Mary E and Gaunt, Tom R and Gho, Johannes M.I.H and Gieger, Christian and Goel, Anuj and Gong, Yan and Isaacs, Aaron and Kleber, Marcus E and Leach, Irene Mateo and McDonough, Caitrin W and Meijs, Matthijs F.L and Melander, Olle and Nelson, Christopher P and Nolte, Ilja M and Pankratz, Nathan and Price, Tom S and Shaffer, Jonathan and Shah, Sonia and Tomaszewski, Maciej and van der Most, Peter J and Van Iperen, Erik P.A and Vonk, Judith M and Witkowska, Kate and Wong, Caroline O.L and Zhang, Li and Beitelshees, Amber L and Berenson, Gerald S and Bhatt, Deepak L and Brown, Morris and Burt, Amber and Cooper-DeHoff, Rhonda M and Connell, John M and Cruickshanks, Karen J and Curtis, Sean P and Davey-Smith, George and Delles, Christian and Gansevoort, Ron T and Guo, Xiuqing and Haiqing, Shen and Hastie, Claire E and Hofker, Marten H and Hovingh, G. Kees and Kim, Daniel S and Kirkland, Susan A and Klein, Barbara E and Klein, Ronald and Li, Yun R and Maiwald, Steffi and Newton-Cheh, Christopher and O’Brien, Eoin T and Onland-Moret, N. Charlotte and Palmas, Walter and Parsa, Afshin and Penninx, Brenda W and Pettinger, Mary and Vasan, Ramachandran S and Ranchalis, Jane E and M Ridker, Paul and Rose, Lynda M and Sever, Peter and Shimbo, Daichi and Steele, Laura and Stolk, Ronald P and Thorand, Barbara and Trip, Mieke D and van Duijn, Cornelia M and Verschuren, W. Monique and Wijmenga, Cisca and Wyatt, Sharon and Young, J. Hunter and Zwinderman, Aeilko H and Bezzina, Connie R and Boerwinkle, Eric and Casas, Juan P and Caulfield, Mark J and Chakravarti, Aravinda and Chasman, Daniel I and Davidson, Karina W and Doevendans, Pieter A and Dominiczak, Anna F and FitzGerald, Garret A and Gums, John G and Fornage, Myriam and ...
American journal of human genetics, ISSN 0002-9297, 2014, Volume 94, Issue 3, pp. 349 - 360
Journal Article
by Randall, Joshua C and Winkler, Thomas W and Kutalik, Zoltán and Berndt, Sonja I and Jackson, Anne U and Monda, Keri L and Kilpeläinen, Tuomas O and Esko, Tõnu and Mägi, Reedik and Li, Shengxu and Workalemahu, Tsegaselassie and Feitosa, Mary F and Croteau-Chonka, Damien C and Day, Felix R and Fall, Tove and Ferreira, Teresa and Gustafsson, Stefan and Locke, Adam E and Mathieson, Iain and Scherag, Andre and Vedantam, Sailaja and Wood, Andrew R and Liang, Liming and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Dermitzakis, Emmanouil T and Dimas, Antigone S and Karpe, Fredrik and Min, Josine L and Nicholson, George and Clegg, Deborah J and Person, Thomas and Krohn, Jon P and Bauer, Sabrina and Buechler, Christa and Eisinger, Kristina and Bonnefond, Amélie and Froguel, Philippe and Hottenga, Jouke-Jan and Prokopenko, Inga and Waite, Lindsay L and Harris, Tamara B and Smith, Albert Vernon and Shuldiner, Alan R and McArdle, Wendy L and Caulfield, Mark J and Munroe, Patricia B and Grönberg, Henrik and Chen, Yii-Der Ida and Li, Guo and Beckmann, Jacques S and Johnson, Toby and Thorsteinsdottir, Unnur and Teder-Laving, Maris and Khaw, Kay-Tee and Wareham, Nicholas J and Zhao, Jing Hua and Amin, Najaf and Oostra, Ben A and Kraja, Aldi T and Province, Michael A and Cupples, L. Adrienne and Heard-Costa, Nancy L and Kaprio, Jaakko and Ripatti, Samuli and Surakka, Ida and Collins, Francis S and Saramies, Jouko and Tuomilehto, Jaakko and Jula, Antti and Salomaa, Veikko and Erdmann, Jeanette and Hengstenberg, Christian and Loley, Christina and Schunkert, Heribert and Lamina, Claudia and Wichmann, H. Erich and Albrecht, Eva and Gieger, Christian and Hicks, Andrew A and Johansson, Åsa and Pramstaller, Peter P and Kathiresan, Sekar and Speliotes, Elizabeth K and Penninx, Brenda and Hartikainen, Anna-Liisa and Jarvelin, Marjo-Riitta and Gyllensten, Ulf and Boomsma, Dorret I and Campbell, Harry and Wilson, James F and Chanock, Stephen J and Farrall, Martin and Goel, Anuj and Medina-Gomez, Carolina and Rivadeneira, Fernando and Estrada, Karol and Uitterlinden, André G and Hofman, Albert and Zillikens, M. Carola and ... and DIAGRAM Consortium and MAGIC Investigators and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy
PLoS genetics, ISSN 1553-7404, 2013, Volume 9, Issue 6, p. e1003500
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Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 11, pp. 1282 - 1293
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