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Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 708 - 11
Cancer is a multifactorial disease driven by a combination of genetic and environmental factors. Many cancer driver mutations have been characterised in... 
LOCALIZATION | BROWSER | NUCLEAR | 5'-UTR | MULTIDISCIPLINARY SCIENCES | TRANSLATION | BCL-2 FAMILY | PROTOONCOGENE | CXCL14 | UNTRANSLATED REGION | SOMATIC MUTATIONS | Nucleotide sequence | Genomes | Environmental factors | Regulatory sequences | Mutation | Gene expression | Ribonucleic acid--RNA | Guanine | Cancer
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 56, pp. 95841 - 95852
Massively parallel DNA sequencing enables the detection of thousands of germline and somatic single nucleotide variants (SNVs) in cancer samples. The... 
Splicing factor mutation | Jurkat | Phosphoproteomics | Proteogenomics | RNA-seq | phosphoproteomics | RNA | STRUCTURAL BASIS | IDENTIFICATION | BINDING | splicing factor mutation | DISCOVERY | CELL BIOLOGY
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 572 - 585
Journal Article
Cancer Research, ISSN 0008-5472, 05/2017, Volume 77, Issue 9, pp. 2522 - 2533
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3319 - 15
Chromosome 17q21-ter is commonly gained in neuroblastoma, but it is unclear which gene in the region is important for tumorigenesis. The JMJD6 gene at... 
ONCOGENES | READ ALIGNMENT | INHIBITION | GENE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | DEPENDENCIES | EXPRESSION | CANCER | DISCOVERY | GAIN | Cell proliferation | Histone deacetylase | Therapy | Cell survival | Transcription | Therapeutic applications | c-Myc protein | Neuroblastoma | Myc protein | Enhancers | Inhibitors | Overexpression | Medical prognosis | Mice | Tumorigenesis | Chromosomes | Chromosome 17 | Tumors | Apoptosis
Journal Article
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 23, pp. 5143 - 5154
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 12/2016, Volume 44, Issue 22, pp. 10644 - 10661
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. E2306 - E2315
Journal Article
Blood, ISSN 0006-4971, 03/2013, Volume 121, Issue 12, pp. 2289 - 2300
Aberrant transcriptional programs in combination with abnormal proliferative signaling drive leukemic transformation. These programs operate in normal... 
GENE-EXPRESSION SIGNATURE | PREDICTS | NUCLEOPHOSMIN | CHROMATIN | ACQUISITION | ERG | MUTATIONS | T-LYMPHOBLASTIC LEUKEMIA | HEMATOLOGY | SUBSET | PROGRESSION | Transcriptional Activation - genetics | Humans | Leukemia, Myeloid, Acute - metabolism | LIM Domain Proteins - metabolism | Trans-Activators - physiology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Proto-Oncogene Protein c-fli-1 - metabolism | Hematopoietic Stem Cells - physiology | Neoplasm Proteins - genetics | GATA2 Transcription Factor - genetics | Neoplastic Stem Cells - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Core Binding Factor Alpha 2 Subunit - metabolism | Proto-Oncogene Protein c-fli-1 - genetics | Leukemia, Myeloid, Acute - pathology | Mice, Transgenic | Gene Expression Regulation, Leukemic | K562 Cells | LIM Domain Proteins - physiology | Mice | Transcriptional Regulator ERG | Prognosis | Neoplasm Proteins - physiology | Core Binding Factor Alpha 2 Subunit - physiology | Neoplasm Proteins - metabolism | Trans-Activators - genetics | T-Cell Acute Lymphocytic Leukemia Protein 1 | Proto-Oncogene Proteins - metabolism | GATA2 Transcription Factor - physiology | Basic Helix-Loop-Helix Transcription Factors - physiology | Transcription Factors - physiology | Cells, Cultured | Proto-Oncogene Protein c-fli-1 - physiology | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - physiology | Animals | Leukemia, Myeloid, Acute - diagnosis | Adaptor Proteins, Signal Transducing - genetics | GATA2 Transcription Factor - metabolism | Proto-Oncogene Proteins - physiology | LIM Domain Proteins - genetics | Trans-Activators - metabolism | Enhancer Elements, Genetic - genetics | Adaptor Proteins, Signal Transducing - metabolism | Core Binding Factor Alpha 2 Subunit - genetics | Leukemia, Myeloid, Acute - genetics
Journal Article