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1. Full Text The CLOSER trial: a multi-center study on the clinical safety and effectiveness of CloserTM VSS, a novel resorbable transfemoral vascular access sealing system
: CHIU WONG et al
by Wong, S. Chiu and Gammon, Roger and Bachinsky, William and O'Shaughnessy, Charles and Leimbach, Wayne and Bernardo, Nelson and Cavros, Nick and Jaff, Michael R and Liu, Ping-Yu and Bergman, Geoffrey
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 11/2017, Volume 90, Issue 5, pp. 798 - 805
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2. Full Text TCT-364 The Closer Large Bore Vascular Sealing System: First-in-Man In-Hospital and Long-Term Experience
by Wong, S. Chiu and Ebner, Adrian
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2019, Volume 74, Issue 13, pp. B361 - B361
Patients | Ultrasonic imaging | Catheters
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3. Full Text Pushing boundaries: Implantation of the 34 mm M edtronic C ore V alve in patients with a large aortic annulus
by Elmously, Adham and Worku, Berhane and Wong, S. Chiu and Salemi, Arash
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 12/2018, Volume 92, Issue 7, pp. 1449 - 1452
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4. Full Text Heparin plus a glycoprotein IIb/IIIa inhibitor versus bivalirudin monotherapy and paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction (HORIZONS-AMI): final 3-year results from a multicentre, randomised controlled trial
by Stone, Gregg W, Dr, Prof and Witzenbichler, Bernhard, MD and Guagliumi, Giulio, MD and Peruga, Jan Z, MD and Brodie, Bruce R, MD and Dudek, Dariusz, MD and Kornowski, Ran, MD and Hartmann, Franz, MD and Gersh, Bernard J, Prof and Pocock, Stuart J, Prof and Dangas, George, Prof and Wong, S Chiu, MD and Fahy, Martin, MSc and Parise, Helen, ScD and Mehran, Roxana, Prof and HORIZONS-AMI Trial Investigators
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9784, pp. 2193 - 2204
Summary Background Primary results of the HORIZONS-AMI trial have been previously reported. In this final report, we aimed to assess 3-year outcomes. Methods... 
Internal Medicine | HARMONIZING OUTCOMES | MEDICINE, GENERAL & INTERNAL | BLOOD-TRANSFUSION | DOUBLE-BLIND | FOLLOW-UP | ACUTE CORONARY SYNDROMES | ST-SEGMENT ELEVATION | PREMATURE DISCONTINUATION | INTERVENTION | ANTIPLATELET THERAPY | CLINICAL-OUTCOMES | Confidence Intervals | Myocardial Infarction - mortality | Paclitaxel - pharmacology | Prospective Studies | Follow-Up Studies | Humans | Heparin - administration & dosage | Male | Recombinant Proteins - adverse effects | Heparin - adverse effects | Hirudins - administration & dosage | Dose-Response Relationship, Drug | Myocardial Infarction - therapy | Platelet Glycoprotein GPIIb-IIIa Complex - administration & dosage | Time Factors | Electrocardiography | Female | Drug Therapy, Combination | Stents | Angioplasty, Balloon - methods | Myocardial Infarction - diagnosis | Drug-Eluting Stents | Drug Administration Schedule | Peptide Fragments - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Combined Modality Therapy | Recombinant Proteins - administration & dosage | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Angioplasty, Balloon - mortality | Hirudins - adverse effects | Survival Analysis | Peptide Fragments - adverse effects | Bivalirudin | Research | Diagnosis | Heparin | Drug therapy | Comparative analysis | Health aspects | Heart attack | Heart attacks | Cardiology | Mortality
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5. Full Text Bivalirudin during Primary PCI in Acute Myocardial Infarction
by Stone, Gregg W and Witzenbichler, Bernhard and Guagliumi, Giulio and Peruga, Jan Z and Brodie, Bruce R and Dudek, Dariusz and Kornowski, Ran and Hartmann, Franz and Gersh, Bernard J and Pocock, Stuart J and Dangas, George and Wong, S. Chiu and Kirtane, Ajay J and Parise, Helen and Mehran, Roxana and HORIZONS AMI Trial Investigators and HORIZONS-AMI Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 05/2008, Volume 358, Issue 21, pp. 2218 - 2230
Bivalirudin is a direct thrombin inhibitor. As compared with a combination of heparin and a glycoprotein IIb/IIIa inhibitor, bivalirudin use resulted in less... 
MEDICINE, GENERAL & INTERNAL | IMPACT | THERAPY | GLYCOPROTEIN IIB/IIIA BLOCKADE | BLOOD-TRANSFUSION | ACUTE CORONARY SYNDROMES | RANDOMIZED CONTROLLED-TRIAL | ACUITY TRIAL | INTERVENTION | ABCIXIMAB | CLINICAL-OUTCOMES | Recombinant Proteins - therapeutic use | Recurrence | Myocardial Infarction - mortality | Humans | Middle Aged | Heparin - therapeutic use | Male | Recombinant Proteins - adverse effects | Heparin - adverse effects | Angioplasty, Balloon, Coronary | Myocardial Infarction - therapy | Aged, 80 and over | Adult | Female | Drug Therapy, Combination | Antithrombins - therapeutic use | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Thrombosis - epidemiology | Combined Modality Therapy | Anticoagulants - adverse effects | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Myocardial Infarction - complications | Stroke - etiology | Thrombosis - etiology | Antithrombins - adverse effects | Hirudins - adverse effects | Aged | Peptide Fragments - adverse effects | Peptide Fragments - therapeutic use | Hemorrhage - chemically induced | Stents - adverse effects | Care and treatment | Coronary artery bypass | Bivalirudin | Drug therapy, Combination | Heparin | Comparative analysis | Health aspects | Heart attack | Stroke | Heart attacks | Ischemia | Cardiology
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6. Full Text Adoption of radial access and comparison of outcomes to femoral access in percutaneous coronary intervention an updated report from the national cardiovascular data registry (2007-2012)
by Feldman, Dmitriy N and Swaminathan, Rajesh V and Kaltenbach, Lisa A and Baklanov, Dmitri V and Kim, Luke K and Wong, S. Chiu and Minutello, Robert M and Messenger, John C and Moussa, Issam and Garratt, Kirk N and Piana, Robert N and Hillegass, William B and Cohen, Mauricio G and Gilchrist, Ian C and Rao, Sunil V
Circulation, ISSN 0009-7322, 06/2013, Volume 127, Issue 23, pp. 2295 - 2306
Background- Radial access for percutaneous coronary intervention (r-PCI) is associated with reduced vascular complications; however, previous reports have... 
Vascular complication | Percutaneous coronary intervention | Radial artery | Hemmorhage | MORTALITY | LEARNING-CURVE | CARDIAC & CARDIOVASCULAR SYSTEMS | vascular complication | METAANALYSIS | RANDOMIZED-TRIALS | hemmorhage | percutaneous coronary intervention | ANGIOGRAPHY | IMPACT | BLOOD-TRANSFUSION | PERIPHERAL VASCULAR DISEASE | radial artery | Postoperative Complications - etiology | Shock, Cardiogenic - epidemiology | Vascular Diseases - etiology | Humans | Middle Aged | Male | Vascular Diseases - epidemiology | Femoral Artery - injuries | Percutaneous Coronary Intervention - methods | Aged, 80 and over | Adult | Female | Registries | Radial Artery - injuries | Retrospective Studies | Intraoperative Complications - epidemiology | Risk Factors | Heart Arrest - epidemiology | Anticoagulants - therapeutic use | Treatment Outcome | Postoperative Complications - epidemiology | Anticoagulants - adverse effects | Shock, Cardiogenic - etiology | Intraoperative Complications - etiology | Heart Arrest - etiology | Percutaneous Coronary Intervention - statistics & numerical data | Aged | Usage | Care and treatment | Cardiovascular diseases | Angioplasty | Patient outcomes
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7. Full Text Balloon valvuloplasty treatment of an infolded CoreValve
: Balloon Valvuloplasty of an Infolded CoreValve
by Kaple, Ryan K and Salemi, Arash and Wong, S. Chiu
Catheterization and Cardiovascular Interventions, ISSN 1522-1946, 02/2017, Volume 89, Issue 3, pp. 499 - 501
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8. Full Text Prognostic impact of staged versus "one-time" multivessel percutaneous intervention in acute myocardial infarction: analysis from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial
by Kornowski, Ran and Mehran, Roxana and Dangas, George and Nikolsky, Eugenia and Assali, Abid and Claessen, Bimmer E and Gersh, Bernard J and Wong, S. Chiu and Witzenbichler, Bernhard and Guagliumi, Giulio and Dudek, Dariusz and Fahy, Martin and Lansky, Alexana J and Stone, Gregg W and HORIZONS-AMI Trial Investigators
Journal of the American College of Cardiology, ISSN 0735-1097, 2011, Volume 58, Issue 7, pp. 704 - 711
The purpose of this study was to compare a one-time primary percutaneous coronary intervention (PCI) of the culprit and nonculprit lesions with PCI of only the... 
coronary artery disease | myocardial infarction | angioplasty | stenting | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | CULPRIT | DISEASE | REPERFUSION | ST-SEGMENT ELEVATION | PRIMARY PCI | CORONARY INTERVENTION | Recurrence | Coronary Vessels - pathology | Prognosis | Humans | Middle Aged | Male | Randomized Controlled Trials as Topic | Angioplasty, Balloon, Coronary - adverse effects | Myocardial Infarction - therapy | Coronary Artery Disease - therapy | Multicenter Studies as Topic | Thrombolytic Therapy | Coronary Artery Disease - pathology | Electrocardiography | Female | Myocardial Infarction - physiopathology | Stents | Confidence intervals | Stroke | Heart attacks | Ischemia | Mortality | Coronary vessels | Cardiovascular disease | Statistical methods | Thrombosis | Molecular weight
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9. Full Text Paclitaxel-Eluting Stents versus Bare-Metal Stents in Acute Myocardial Infarction
by Stone, Gregg W and Lansky, Alexandra J and Pocock, Stuart J and Gersh, Bernard J and Dangas, George and Wong, S. Chiu and Witzenbichler, Bernhard and Guagliumi, Giulio and Peruga, Jan Z and Brodie, Bruce R and Dudek, Dariusz and Möckel, Martin and Ochala, Andrzej and Kellock, Alison and Parise, Helen and Mehran, Roxana and HORIZONS-AMI Trial Investigators
The New England Journal of Medicine, ISSN 0028-4793, 05/2009, Volume 360, Issue 19, pp. 1946 - 1959
Acute ST-segment elevation myocardial infarction is often treated with immediate coronary stenting of the infarct-related artery. The use of a... 
MEDICINE, GENERAL & INTERNAL | ANGIOPLASTY | RANDOMIZED-TRIALS | EFFICACY | THROMBOSIS | SAFETY | FOLLOW-UP | OFF-LABEL | OUTCOMES | CORONARY-ARTERY | REGISTRY | Recurrence | Myocardial Infarction - mortality | Follow-Up Studies | Humans | Middle Aged | Male | Risk | Angioplasty, Balloon, Coronary | Drug-Eluting Stents - adverse effects | Myocardial Infarction - therapy | Sweden | Fibrinolytic Agents - therapeutic use | Aged, 80 and over | Adult | Female | Paclitaxel - administration & dosage | Coronary Stenosis - therapy | Kaplan-Meier Estimate | Coronary Restenosis - prevention & control | Retreatment - statistics & numerical data | Combined Modality Therapy | Coronary Angiography | Coronary Restenosis - epidemiology | Myocardial Infarction - drug therapy | Aged | Stents - adverse effects | Evaluation | Care and treatment | Coronary restenosis | Paclitaxel | Dosage and administration | Drug therapy | Health aspects | Heart attack | Stent (Surgery) | Stents | Heart attacks
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10. Full Text The OPTIMIZE randomized trial to assess safety and efficacy of the Svelte IDS and RX Sirolimus-eluting coronary stent Systems for the Treatment of atherosclerotic lesions: Trial design and rationale
by Mauri, Laura and Doros, Gheorghe and Rao, Sunil V and Cohen, David J and Yakubov, Steven and Lasala, John and Wong, S. Chiu and Zidar, James and Kereiakes, Dean J
American Heart Journal, ISSN 0002-8703, 10/2019, Volume 216, pp. 82 - 90
Coronary stenting without angioplasty pretreatment (direct stenting) may simplify procedures in appropriate lesions. Direct stenting is facilitated by smaller... 
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11. Full Text Bivalirudin in patients undergoing primary angioplasty for acute myocardial infarction (HORIZONS-AMI): 1-year results of a randomised controlled trial
by Mehran, Roxana, Dr and Lansky, Alexandra J, MD and Witzenbichler, Bernhard, MD and Guagliumi, Giulio, MD and Peruga, Jan Z, MD and Brodie, Bruce R, MD and Dudek, Dariusz, MD and Kornowski, Ran, MD and Hartmann, Franz, MD and Gersh, Bernard J, Prof and Pocock, Stuart J, Prof and Wong, S Chiu, MD and Nikolsky, Eugenia, MD and Gambone, Louise, MD and Vandertie, Lynn and Parise, Helen, ScD and Dangas, George D, MD and Stone, Gregg W, Prof and HORIZONS-AMI Trial Investigators
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9696, pp. 1149 - 1159
Summary Background In the HORIZONS-AMI trial, patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | IMPACT | GLYCOPROTEIN IIB/IIIA BLOCKADE | BLOOD-TRANSFUSION | RISK | ACUTE CORONARY SYNDROMES | ACUITY TRIAL | ABCIXIMAB | INTERVENTION | ANTIPLATELET THERAPY | CLINICAL-OUTCOMES | Recombinant Proteins - therapeutic use | Myocardial Infarction - mortality | Follow-Up Studies | Humans | Middle Aged | Heparin - therapeutic use | Male | Recombinant Proteins - adverse effects | Heparin - adverse effects | Angioplasty, Balloon, Coronary - adverse effects | Aged, 80 and over | Adult | Female | Thrombosis - prevention & control | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Hemorrhage - epidemiology | Kaplan-Meier Estimate | Proportional Hazards Models | Anticoagulants - therapeutic use | Survival Rate | Treatment Outcome | Anticoagulants - adverse effects | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Myocardial Infarction - drug therapy | Thrombosis - etiology | Hirudins - adverse effects | Aged | Peptide Fragments - adverse effects | Peptide Fragments - therapeutic use | Hemorrhage - chemically induced | Stents - adverse effects | Care and treatment | Angioplasty | Patient outcomes | Bivalirudin | Dosage and administration | Health aspects | Heart attack | Clinical trials | Cardiovascular disease | Heart attacks | Drug therapy | Mortality
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12. Full Text Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings
by Yoon, Sung-Han and Whisenant, Brian K and Bleiziffer, Sabine and Delgado, Victoria and Schofer, Niklas and Schofer, Joachim and Eschenbach, Lena and Fujita, Buntaro and Sharma, Rahul and Ancona, Marco and Yzeiraj, Ermela and Cannata, Stefano and Barker, Colin and Davies, James E and Frangieh, Antonio H and Deuschl, Florian and Podlesnikar, Tomaz and Asami, Masahiko and Dhoble, Abhijeet and Chyou, Anthony and Masson, Jean-Bernard and Wijeysundera, Harindra C and Blackman, Daniel J and Rampat, Rajiv and Taramasso, Maurizio and Gutierrez-Ibanes, Enrique and Chakravarty, Tarun and Attizzani, Guiherme F and Kaneko, Tsuyoshi and Wong, S. Chiu and Sievert, Horst and Nietlispach, Fabian and Hildick-Smith, David and Nombela-Franco, Luis and Conradi, Lenard and Hengstenberg, Christian and Reardon, Michael J and Kasel, Albert Markus and Redwood, Simon and Colombo, Antonio and Kar, Saibal and Maisano, Francesco and Windecker, Stephan and Pilgrim, Thomas and Ensminger, Stephan M and Prendergast, Bernard D and Schaefer, Ulrich and Bax, Jeroen J and Latib, Azeem and Makkar, Raj R
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2017, Volume 70, Issue 9, pp. 1121 - 1131
Limited data exist regarding transcatheter mitral valve replacement (TMVR) for patients with failed mitral valve replacement and repair. This study sought to... 
degenerated bioprostheses | mitral valve | transcatheter valve implantation | annuloplasty ring | CARDIAC & CARDIOVASCULAR SYSTEMS | CLINICAL-TRIAL | LONG-TERM SURVIVAL | IN-VALVE | END-POINT DEFINITIONS | HIGH-RISK PATIENTS | TRIAL DESIGN PRINCIPLES | HEART-VALVES | ACADEMIC RESEARCH CONSORTIUM | CALCIFIC AORTIC-STENOSIS | ANNULAR CALCIFICATION | Reoperation | Survival Rate - trends | Humans | Bioprosthesis - adverse effects | Europe - epidemiology | Heart Valve Prosthesis Implantation - methods | Male | Mitral Valve - surgery | Treatment Outcome | Heart Valve Diseases - surgery | Prosthesis Design | Prosthesis Failure | Cardiac Catheterization - methods | Female | Aged | Retrospective Studies | North America - epidemiology | Mitral Valve Annuloplasty - adverse effects | Heart valve diseases | Analysis | Heart | Mitral valve | Vascular implants | Kidneys | Risk groups | Complications | Heart surgery | Mortality | Clinical trials | Implantation | Thorax | Patients | Thrombosis | Bleeding | Catheters | Regurgitation | Ventricle | Mercury | Ejection | Kidney transplantation
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