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Neurobiology of Aging, ISSN 0197-4580, 2019
Mutations in presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid precursor protein (APP) are major genetic causes of early-onset Alzheimer's disease... 
PSEN2 | PSEN1 | Early-onset Alzheimer's disease | Exome sequencing
Journal Article
Parkinsonism and Related Disorders, ISSN 1353-8020, 08/2019, Volume 65, pp. 243 - 247
To analyse variants, recently associated with the development of Parkinson's disease (PD), Parkinson's disease dementia (PDD) and dementia with Lewy bodies... 
LRP10 gene | Walcheren population | Parkinson's disease | Parkinson's disease dementia | Dementia with Lewy bodies | Analysis | Dementia
Journal Article
Hong Kong Journal of Emergency Medicine, ISSN 1024-9079, 2019, p. 102490791982567
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2015, Volume 11, Issue 7, pp. P490 - P490
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2013, Volume 9, Issue 4, pp. P560 - P560
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2017, Volume 26, Issue 3, pp. 493 - 508.e4
Type 2 cytokines are important signals triggering biogenesis of thermogenic beige adipocytes in white adipose tissue (WAT) during cold acclimation. However,... 
adipose remodeling | macrophages | adipocyte precursor cells | beiging | adaptive thermogenesis | eotaxin | eosinophils | type 2 immunity | ANTIDIABETIC ACTIONS | CELLS | ENERGY-EXPENDITURE | ADIPOCYTES | ADIPONECTIN | EOSINOPHILS | ENDOCRINOLOGY & METABOLISM | INSULIN SENSITIVITY | EOTAXIN | GROWTH-FACTOR 21 | FGF21 | CELL BIOLOGY | Eosinophils - metabolism | Eosinophils - drug effects | Sympathetic Nervous System - drug effects | Adaptation, Physiological - drug effects | Glucuronidase - metabolism | Adipose Tissue, White - metabolism | Adipocytes - cytology | Male | Autocrine Communication - drug effects | Stem Cells - cytology | Adipocytes - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Stem Cells - metabolism | Sympathetic Nervous System - metabolism | Immunity - drug effects | Fibroblast Growth Factors - metabolism | Cold Temperature | Chemokine CCL11 - metabolism | Mice, Inbred C57BL | Fibroblast Growth Factors - deficiency | Recombinant Proteins - pharmacology | Mice, Knockout | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Adipocytes - metabolism | Stem Cells - drug effects | Adipose Tissue, Beige - drug effects | Macrophages - drug effects | Cell Proliferation - drug effects | Thermogenesis - drug effects | Adipose Tissue, Beige - metabolism | Adipose Tissue, White - drug effects | Adipose tissues | Fibroblast growth factors | Immune response | Macrophages | Pharmaceutical biotechnology
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1241 - 1241
Journal Article
Journal Article
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 02/2019, Volume 74, pp. 225 - 233
Knowledge about the molecular mechanisms driving Alzheimer's disease (AD) is still limited. To learn more about AD biology, we performed whole transcriptome... 
RNA sequencing | Alzheimer's disease | Protein-protein interactions | Hippocampus | DNA METHYLATION | SYNAPTIC ACTIVITY | TAU | NETWORKS | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | CONSORTIUM | DATABASE | ANNOTATION | HYPOTHESIS | ONTOLOGY | DIFFERENTIAL EXPRESSION ANALYSIS
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 08/2017, Volume 25, Issue 8, pp. 973 - 981
Accumulating evidence suggests that genetic variants in the SORL1 gene are associated with Alzheimer disease (AD), but a strategy to identify which variants... 
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 01/2019, Volume 73, pp. 229.e11 - 229.e18
Next-generation sequencing has contributed to our understanding of the genetics of Alzheimer's disease (AD) and has explained a substantial part of the missing... 
EIF2AK3 | PERK | Alzheimer's disease | Exome sequencing | GENETIC-VARIATION | UNFOLDED PROTEIN RESPONSE | MOUSE MODEL | NEURODEGENERATION | ASSOCIATION | NEUROSCIENCES | MISSENSE MUTATIONS | GERIATRICS & GERONTOLOGY | Proteins | Immunohistochemistry | Neurosciences | RNA | Medical genetics | Epidemiology | Protein kinases
Journal Article
Brain: a journal of neurology, ISSN 0006-8950, 2014, Volume 137, Issue Pt 5, pp. 1361 - 73
Journal Article