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Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 6, pp. 751 - 757
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, pp. 18995 - 18995
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2013, Volume 45, Issue 12, pp. 1474 - 1478
Journal Article
Human Pathology, ISSN 0046-8177, 2015, Volume 52, pp. 47 - 54
Abstract RING finger E3 ligases have roles in processes central to maintenance of genomic integrity and cellular homeostasis. Many RING finger E3 ligases are... 
Pathology | Ring finger protein 43 | Somatic mutation | Prognosis | Polymorphisms | Intrahepatic cholangiocarcinoma | UNITED-STATES | SYSTEM | RNF43 | TRANSCRIPTION FACTOR-BINDING | PANCREAS | SITE-DIRECTED MUTATIONS | PATHOLOGY | RSNP-GUIDE | TUMORS | PAPILLARY-MUCINOUS NEOPLASMS | PATHOLOGICAL FEATURES | Immunohistochemistry | Oncogene Proteins - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | DNA-Binding Proteins - analysis | Male | Bile Duct Neoplasms - enzymology | DNA Mutational Analysis | Female | Bile Duct Neoplasms - genetics | Oncogene Proteins - analysis | Real-Time Polymerase Chain Reaction | Cholangiocarcinoma - enzymology | Genetic Predisposition to Disease | Biomarkers, Tumor - analysis | Down-Regulation | RNA, Messenger - genetics | Cholangiocarcinoma - mortality | Kaplan-Meier Estimate | DNA-Binding Proteins - genetics | Polymorphism, Genetic | Cholangiocarcinoma - pathology | Phenotype | Bile Duct Neoplasms - mortality | Cholangiocarcinoma - genetics | Biomarkers, Tumor - genetics | Bile Duct Neoplasms - pathology | Mutation | Genetic research | RNA | Ligases | Analysis | Electrochemistry | Electrochemical reactions | Messenger RNA | Medical research | Data analysis | Statistical analysis | Genes | Mortality | Proteins | Studies | Polymerase chain reaction | Confidence intervals | Chemotherapy | Rodents | Medical prognosis | Protein expression | Polyclonal antibodies | Bile | Cancer | Index Medicus
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 6, pp. 751 - 757
Berberine is a natural compound found in several herbs. Anticancer activity of berberine was reported in several cancers, however, little is known regarding... 
Journal Article
Nature Communications, ISSN 2041-1723, 07/2014, Volume 5, Issue 1, pp. 4378 - 4378
Journal Article
Molecular Cancer, ISSN 1476-4598, 08/2011, Volume 10, Issue 1, pp. 102 - 102
Background: Cyclophilin A (CypA) expression is associated with malignant phenotypes in many cancers. However, the role and mechanisms of CypA in liver... 
Cell proliferation | ERK1/2 pathway | Cyclophilin A | Cyclosporin A | CD147 | Peptidyprolyl cis-trans isomerase | Cholangiocarcinoma | CANCER-CELLS | INTRAHEPATIC CHOLANGIOCARCINOMA | OXIDATIVE STRESS | PROTEIN | cell proliferation | cyclophilin A | BIOCHEMISTRY & MOLECULAR BIOLOGY | cyclosporin A | peptidyprolyl cis-trans isomerase | LUNG-CANCER | CYCLOSPORINE-A | ONCOLOGY | IN-VIVO | SMOOTH-MUSCLE-CELLS | cholangiocarcinoma | INHIBITORY FACTOR | T-CELLS | Cholangiocarcinoma - parasitology | Humans | Male | Cholangiocarcinoma - etiology | Bile Ducts, Intrahepatic - drug effects | Cyclophilin A - physiology | Bile Ducts, Intrahepatic - metabolism | Fasciola hepatica - physiology | Tumor Burden - genetics | Cyclophilin A - genetics | Bile Duct Neoplasms - genetics | Gene Expression Regulation, Neoplastic - drug effects | Fascioliasis - complications | Bile Ducts, Intrahepatic - parasitology | Cyclophilin A - metabolism | Bile Ducts, Intrahepatic - pathology | RNA, Small Interfering - pharmacology | Up-Regulation - genetics | Bile Duct Neoplasms - parasitology | Fascioliasis - genetics | Bile Duct Neoplasms - etiology | Fascioliasis - pathology | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Cyclophilin A - antagonists & inhibitors | Cholangiocarcinoma - pathology | Animals | Tumor Burden - drug effects | Mice, Nude | Cell Line, Tumor | Cholangiocarcinoma - genetics | Cell Proliferation - drug effects | Mice | Bile Duct Neoplasms - pathology | Cyclophilin | Physiological aspects | Research | Medicine | Liver cancer | Protein folding | Mortality | Colleges & universities | Hypoxia | Standard deviation | Drug resistance | Cancer therapies | Tumors | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 10/2018, Volume 37, Issue 42, pp. 5648 - 5665
Journal Article
Anticancer Research, ISSN 0250-7005, 11/2016, Volume 36, Issue 11, pp. 5965 - 5973
The treatment of cholangiocarcinoma (CCA) is still ineffective and the search for a novel treatment is needed. In this study, eight novel mono-triazole... 
Cell growth | Glycoside | arrest | Cholangiocarcinoma | Cell apoptosis | Triazoles - pharmacology | Cholangiocarcinoma - pathology | Apoptosis - drug effects | Triazoles - chemistry | Humans | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Cycle - drug effects | Glycosides - pharmacology | Glycosides - chemistry | Index Medicus
Journal Article
Journal Article
Cancer Epidemiology, ISSN 1877-7821, 2015, Volume 39, Issue 3, pp. 274 - 278
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e106056 - e106056
Background: Up-regulation and association of nuclear factor kappa B (NF-kappa B) with carcinogenesis and tumor progression has been reported in several... 
CANCER-CELLS | APOPTOSIS | OPISTHORCHIS-VIVERRINI | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | PANCREATIC-CANCER | ADENOCARCINOMA CELLS | CELL-CYCLE ARREST | ANTITUMOR-ACTIVITY | NUCLEAR TRANSLOCATION | Immunohistochemistry | Opisthorchis - physiology | Liver - pathology | Apoptosis - drug effects | Humans | Middle Aged | Male | Janus Kinase 3 - deficiency | Cholangiocarcinoma - metabolism | Dose-Response Relationship, Drug | Bile Ducts, Intrahepatic | Female | Tumor Burden - genetics | Benzamides - pharmacology | Bile Duct Neoplasms - complications | NF-kappa B - antagonists & inhibitors | Bile Duct Neoplasms - metabolism | Cholangiocarcinoma - complications | Liver - metabolism | Opisthorchiasis - complications | Cyclohexanones - pharmacology | Mice, SCID | Blotting, Western | Mice, Knockout | Opisthorchiasis - metabolism | Xenograft Model Antitumor Assays | Host-Parasite Interactions - drug effects | Cholangiocarcinoma - pathology | Opisthorchiasis - parasitology | Animals | Tumor Burden - drug effects | NF-kappa B - biosynthesis | Janus Kinase 3 - genetics | Mice, Inbred NOD | Bile Duct Neoplasms - pathology | Liver - parasitology | Flow cytometry | Therapy | Biotechnology | Bcl-2 protein | Liver | XIAP protein | Biochemistry | Metastasis | Assaying | Cancer therapies | Carcinogenesis | Carcinogens | Animal tissues | DNA fragmentation | Inhibition | Cholangiocarcinoma | Deoxyribonucleic acid--DNA | NF-κB protein | Cytokines | Therapeutic applications | Mortality | Caspase | Patients | Bile duct | Medicine | Cytometry | Thyroid cancer | Cell lines | Mice | Apoptosis | Bile | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article