Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (398) 398
Patent (92) 92
Publication (52) 52
Book Review (19) 19
Book / eBook (16) 16
Dissertation (14) 14
Newspaper Article (11) 11
Conference Proceeding (8) 8
Book Chapter (5) 5
Magazine Article (2) 2
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (204) 204
humans (172) 172
female (121) 121
male (114) 114
human necessities (92) 92
hygiene (92) 92
medical or veterinary science (92) 92
preparations for medical, dental, or toilet purposes (77) 77
adult (72) 72
middle aged (71) 71
aged (60) 60
chemistry (49) 49
chemical aspects of bandages, dressings, absorbent pads, orsurgical articles (48) 48
disinfection, sterilisation, or deodorisation of air (48) 48
materials for bandages, dressings, absorbent pads, or surgicalarticles (48) 48
metallurgy (48) 48
methods or apparatus for sterilising materials or objects ingeneral (48) 48
animal and vegetable oils, fats, fatty substances and waxes (45) 45
candles (45) 45
detergent compositions (45) 45
detergents (45) 45
fatty acids therefrom (45) 45
recovery of glycerol (45) 45
resin soaps (45) 45
soap or soap-making (45) 45
use of single substances as detergents (45) 45
abridged index medicus (43) 43
analysis (43) 43
flexible materials not otherwise provided for (42) 42
laundering (42) 42
oncology (42) 42
paper (42) 42
textiles (42) 42
treatment of textiles or the like (42) 42
treatment, not provided for elsewhere in class d06, of fibres, threads, yarns,fabrics, feathers, or fibrous goods made from such materials (42) 42
article (39) 39
laundering, drying, ironing, pressing or folding textilearticles (38) 38
animals (37) 37
adolescent (36) 36
research (36) 36
specific use of cosmetics or similar toiletpreparations (33) 33
cancer (32) 32
risk factors (31) 31
specific therapeutic activity of chemical compounds ormedicinal preparations (31) 31
treatment outcome (27) 27
aged, 80 and over (25) 25
child (23) 23
retrospective studies (22) 22
essential oils (21) 21
health aspects (21) 21
mice (21) 21
perfumes (21) 21
producing, refining and preservingfats, fatty substances (21) 21
care and treatment (20) 20
young adult (20) 20
immunology (19) 19
multidisciplinary sciences (19) 19
studies (19) 19
child, preschool (18) 18
medical and health sciences (18) 18
medicin och hälsovetenskap (18) 18
surgery (18) 18
expression (17) 17
prognosis (17) 17
disease (16) 16
follow-up studies (16) 16
genetic aspects (16) 16
medical research (16) 16
medicine & public health (16) 16
risk (16) 16
medicine, general & internal (15) 15
patients (15) 15
epidemiology (14) 14
further section (14) 14
gene expression (14) 14
genes (14) 14
hospitals (14) 14
population (14) 14
prevalence (14) 14
transplantation (14) 14
biochemistry & molecular biology (13) 13
cardiac & cardiovascular systems (13) 13
children (13) 13
genetics & heredity (13) 13
genotype (13) 13
hematology (13) 13
pharmacology & pharmacy (13) 13
clinical trials (12) 12
genetic predisposition to disease (12) 12
genetics (12) 12
health sciences (12) 12
medical colleges (12) 12
pediatrics (12) 12
prospective studies (12) 12
proteins (12) 12
time factors (12) 12
adults (11) 11
biotechnology & applied microbiology (11) 11
carcinoma (11) 11
clinical medicine (11) 11
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (8) 8
Gerstein Science - Stacks (3) 3
UofT at Scarborough - Stacks (3) 3
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
UofT at Mississauga - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Engineering & Comp. Sci. - Missing (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Faculty of Information - Stacks (1) 1
New College (Ivey) - Stacks (1) 1
Trinity College (John W Graham) - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (506) 506
French (31) 31
German (14) 14
Portuguese (8) 8
Spanish (7) 7
Chinese (4) 4
Korean (4) 4
Turkish (4) 4
Norwegian (2) 2
Croatian (1) 1
Czech (1) 1
Danish (1) 1
Greek (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Therapeutic advantage of anti-VAP-1 over anti-[alpha]4 integrin antibody in concanavalin a-induced hepatitis
by Woo-Yong Lee and Marko Salmi and Margaret M Kelly and Sirpa Jalkanen and Paul Kubes
Hepatology, ISSN 0270-9139, 10/2013, Volume 58, Issue 4, p. 1413
  Hepatitis induced by concanavalin A (Con A) in mice is well known to be a T-lymphocyte-mediated injury. It has been reported that T helper (Th)1 and Th2... 
Lymphocytes | Liver | Rodents | Hepatology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Middle east respiratory syndrome coronavirus (MERS-CoV): Announcement of the coronavirus study group
by Groot, Raoul and Baker, Susan and Baric, Ralph and Brown, C.S and sten, Christian and Enjuanes, Luis and Fouchier, Ron and Galiano, Monica and Gorbalenya, Alexander and Memish, Ziad and Perlman, Stanley and Poon, Leo and Snijder, Eric and Stephens, Gwen and Woo, Margaret M and Zaki, Ali and Zambon, Maria and Ziebuhr, John
Journal of Virology, ISSN 0022-538X, 07/2013, Volume 87, Issue 14, pp. 7790 - 7792
VIROLOGY | Middle East - epidemiology | Coronaviridae - classification | Coronavirus Infections - epidemiology | Species Specificity | Humans | Phylogeny | Cluster Analysis | Coronaviridae - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
by Estrada Gil, Karol and Styrkarsdottir, Unnur and Evangelou, Evangelos and Hsu, Yi-Hsiang and Duncan, Emma and Ntzani, Evangelia and Oei, Ling and Albagha, Omar M and Amin, Najaf and Kemp, John and Koller, Daniel and Li, Guo and Liu, Ching-Ti and Minster, Ryan and Moayyeri, Alireza and Vandenput, Liesbeth and Willner, Dana and Xiao, Su-Mei and Yerges-Armstrong, Laura and Zheng, Hou-Feng and Alonso, Nerea and Eriksson, Joel and Kammerer, Candace and Kaptoge, Stephen and Leo, Paul and Thorleifsson, Gudmar and Wilson, Scott and Wilson, James and Aalto, Ville and Alen, Theo and Aragaki, Aaron and Aspelund, Thor and Center, Jacqueline and Dailiana, Zoe and Duggan, C and Garcia, Melissa and Garcia-Giralt, Natàlia and Giroux, Sylvie and Hallmans, Göran and Hocking, Lynne and Husted, Lise Bjerre and Jameson, Karen and Khusainova, Rita and Kim, Ghi Su and Kooperberg, Charles and Koromila, Theodora and Kruk, Marcin and Laaksonen, Marika and LaCroix, Anea and Lee, Seung and Leung, Ping and Lewis, Joshua and Masi, Laura and Mencej-Beac, Simona and Nguyen, Tuan and Nogues, Xavier and Patel, Millan and Prezelj, Janez and Rose, Lynda and Scollen, Serena and Siggeirsdottir, Kristin and Smith, G.D and Svensson, Olle and Trompet, Stella and Trummer, Olivia and Schoor, Natasja and Woo, Margaret M and Zhu, Kun and Balcells, Susana and Brandi, M.L and Buckley, Brendan M and Cheng, Sulin and Christiansen, C and Cooper, Charles and Dedoussis, George and Ford, Ian and Frost, Morten and Goltzman, David and González-Macías, Jesús and Kähönen, Mika and Karlsson, Magnus and Khusnutdinova, Elza and Koh, Jung-Min and Kollia, Panagoula and Langdahl, Bente and Leslie, William and Lips, Paul and Ljunggren, Östen and Lorenc, Roman and Marc, Janja and Mellström, Dan and Obermayer-Pietsch, Barbara and Olmos, David and Pettersson-Kymmer, Ulrika and Reid, David and Riancho, José and Ridker, Paul and Rousseau, Francois and Lagboom, P Eline and Tang, Nelson L and ... and Medicinska fakulteten and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Klinisk farmakologi and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 491 - 501
textabstractBone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and... 
WOMEN | POPULATION | IMPUTATION | VARIANTS | DISEASE | GENETICS & HEREDITY | OSTEOPOROTIC FRACTURES | GENE-EXPRESSION | LRP5 | PATTERNS | IMPUTED DATA | Glycoproteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Computational Biology | Intercellular Signaling Peptides and Proteins - genetics | European Continental Ancestry Group | Genotype | Male | Bone Density - genetics | Gene Expression Profiling | Phosphoproteins - genetics | Fractures, Bone - genetics | Mitochondrial Membrane Transport Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Female | Femur Neck - physiopathology | Osteoporosis - genetics | Spectrin - genetics | Quantitative Trait Loci | Lumbar Vertebrae - physiopathology | Quantitative trait loci | Measurement | Fractures | Bones | Genetic aspects | Identification and classification | Density | Risk factors | Medical research | Osteoporosis | Genomics | Bone density | Gene loci | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | ortopedi | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | genetik | Genetics | Orthopaedics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled ^sup 14^C material in advanced cancer patients
by Sally Clive and Margaret M Woo and Thomas Nydam and Lindsay Kelly and Margaret Squier and Mark Kagan
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2012, Volume 70, Issue 4, p. 513
  Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion profiles were... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled super(14)C material in advanced cancer patients
by Clive, Sally and Woo, Margaret M and Nydam, Thomas and Kelly, Lindsay and Squier, Margaret and Kagan, Mark
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2012, Volume 70, Issue 4, pp. 513 - 522
Purpose: Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled 14C material in advanced cancer patients
by Clive, Sally and Woo, Margaret M and Nydam, Thomas and Kelly, Lindsay and Squier, Margaret and Kagan, Mark
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2012, Volume 70, Issue 4, pp. 513 - 522
Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion profiles were... 
Panobinostat | Excretion | Medicine & Public Health | Disposition | Oncology | Cancer Research | Pharmacology/Toxicology | Metabolism | DACi | Antineoplastic Agents - metabolism | Histone Deacetylase Inhibitors - pharmacokinetics | Administration, Oral | Humans | Middle Aged | Female | Indoles - pharmacokinetics | Male | Carbon Radioisotopes | Hydroxamic Acids - pharmacokinetics | Neoplasms - drug therapy | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Analysis of genetic and environmental risk factors and their interactions in Korean patients with age-related macular degeneration
by Woo, Se Joon and Ahn, Jeeyun and Morrison, Margaux A and Ahn, So Yeon and Lee, Jaebong and Kim, Ki Woong and DeAngelis, Margaret M and Park, Kyu Hyung
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0132771 - e0132771
Purpose To investigate the association of genetic and environmental factors, and their interactions in Korean patients with exudative age-related macular... 
FACTOR-H GENE | POPULATION | CIGARETTE-SMOKING | LOC387715/HTRA1 POLYMORPHISMS | CFH | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | JAPANESE | PREVALENCE | POLYPOIDAL CHOROIDAL VASCULOPATHY | ASSOCIATION | Humans | Macular Degeneration - complications | Risk Factors | Asian Continental Ancestry Group - genetics | Male | Gene-Environment Interaction | Macular Degeneration - genetics | Macular Degeneration - epidemiology | Environment | Female | Aged | Republic of Korea - epidemiology | Choroidal Neovascularization - complications | Angiography | Disease | Pathogenesis | Myopia | Systematic review | Single-nucleotide polymorphism | Hemorrhage | Risk factors | Vascularization | Ecological risk assessment | Information systems | Macular degeneration | Body mass index | Regression models | Vascular diseases | Education | Degeneration | Genetic factors | Ophthalmology | Age | Genotypes | Hypertension | Medical research | Medical imaging | Hyperlipidemia | Environmental factors | Regression analysis | Risk analysis | Patients | Environmental risk | Meta-analysis | Medicine | Studies | Hospitals | Optical Coherence Tomography | Diet | Equivalence | Body mass | Body size | Fluorescein | Gene loci | Exudation | Health risk assessment | Habits | Smoking | Index Medicus | Risk
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
by Wyss, Annah B and Sofer, Tamar and Lee, Mi Kyeong and Terzikhan, Natalie and Nguyen, Jennifer N and Lahousse, Lies and Latourelle, Jeanne C and Smith, Albert Vernon and Bartz, Traci M and Feitosa, Mary F and Gao, Wei and Ahluwalia, Tarunveer S and Tang, Wenbo and Oldmeadow, Christopher and Duan, Qing and de Jong, Kim and Wojczynski, Mary K and Wang, Xin-Qun and Noordam, Raymond and Hartwig, Fernando Pires and Jackson, Victoria E and Wang, Tianyuan and Obeidat, Ma’en and Hobbs, Brian D and Huan, Tianxiao and Gui, Hongsheng and Parker, Margaret M and Hu, Donglei and Mogil, Lauren S and Kichaev, Gleb and Jin, Jianping and Graff, Mariaelisa and Harris, Tamara B and Kalhan, Ravi and Heckbert, Susan R and Paternoster, Lavinia and Burkart, Kristin M and Liu, Yongmei and Holliday, Elizabeth G and Wilson, James G and Vonk, Judith M and Sanders, Jason L and Barr, R. Graham and de Mutsert, Renée and Menezes, Ana Maria Baptista and Adams, Hieab H. H and van den Berge, Maarten and Joehanes, Roby and Levin, Albert M and Liberto, Jennifer and Launer, Lenore J and Morrison, Alanna C and Sitlani, Colleen M and Celedón, Juan C and Kritchevsky, Stephen B and Scott, Rodney J and Christensen, Kaare and Rotter, Jerome I and Bonten, Tobias N and Wehrmeister, Fernando César and Bossé, Yohan and Xiao, Shujie and Oh, Sam and Franceschini, Nora and Brody, Jennifer A and Kaplan, Robert C and Lohman, Kurt and McEvoy, Mark and Province, Michael A and Rosendaal, Frits R and Taylor, Kent D and Nickle, David C and Williams, L. Keoki and Burchard, Esteban G and Wheeler, Heather E and Sin, Don D and Gudnason, Vilmundur and North, Kari E and Fornage, Myriam and Psaty, Bruce M and Myers, Richard H and O’Connor, George and Hansen, Torben and Laurie, Cathy C and Cassano, Patricia A and Sung, Joohon and Kim, Woo Jin and Attia, John R and Lange, Leslie and Boezen, H. Marike and Thyagarajan, Bharat and Rich, Stephen S and Mook-Kanamori, Dennis O and Horta, Bernardo Lessa and Uitterlinden, André G and Im, Hae Kyung and Cho, Michael H and Brusselle, Guy G and Gharib, Sina A and Dupuis, Josée and ...
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2976 - 15
Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by... 
SMOOTH-MUSCLE | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | LUNG-FUNCTION | FOLLOW-UP | LARGE-SCALE | SEGREGATION ANALYSIS | SMOKING-BEHAVIOR | GENOME-WIDE ASSOCIATION | AIR-FLOW OBSTRUCTION | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Lung Diseases - ethnology | Genomics | Humans | Pulmonary Disease, Chronic Obstructive | Hispanic Americans | Male | Lung - physiology | Linkage Disequilibrium | Forced Expiratory Volume | Regression Analysis | Vital Capacity | Lung Diseases - genetics | Sample Size | Female | Polymorphism, Single Nucleotide | African Continental Ancestry Group - genetics | Asian Americans | Quantitative Trait Loci | Smoking | Respiratory function | Lung | Genes | Linkage disequilibrium | Genomes | Gene expression | Loci | Proteins | Ethnicity | Annotations | Pulmonary functions | Genetics | Gene mapping | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease
by Hobbs, Brian D and Parker, Margaret M and Chen, Han and Lao, Taotao and Hardin, Megan and Qiao, Dandi and Hawrylkiewicz, Iwona and Sliwinski, Pawel and Yim, Jae-Joon and Kim, Woo Jin and Kim, Deog Kyeom and Castaldi, Peter J and Hersh, Craig P and Morrow, Jarrett and Celli, Bartolome R and Pinto-Plata, Victor M and Criner, Gerald J and Marchetti, Nathaniel and Bueno, Raphael and Agusti, Alvar and Make, Barry J and Crapo, James D and Calverley, Peter M and Donner, Claudio F and Lomas, David A and Wouters, Emiel F. M and Vestbo, Jorgen and Pare, Peter D and Levy, Robert D and Rennard, Stephen I and Zhou, Xiaobo and Laird, Nan M and Lin, Xihong and Beaty, Terri H and Silverman, Edwin K and Cho, Michael H and Int COPD Genetics Network Investig and NETT Genetics Investigators and ECLIPSE Investigators and COPDGene Investigators and International COPD Genetics Network Investigators
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2016, Volume 194, Issue 1, pp. 48 - 57
Rationale: Chronic obstructive pulmonary disease (COPD) susceptibility is in part related to genetic variants. Most genetic studies have been focused on... 
Exome | IL-27 | Genetics | Chronic Obstructive Pulmonary Disease | CROHNS-DISEASE | LOW-FREQUENCY | LUNG-FUNCTION | I INTERFERON | genetics | exome | INFLAMMATORY-BOWEL-DISEASE | RESPIRATORY SYSTEM | GENE-EXPRESSION | MULTIPLE LOCI | END-PRODUCTS RAGE | chronic obstructive pulmonary disease | GENOME-WIDE ASSOCIATION | COPD | CRITICAL CARE MEDICINE | Exome - genetics | Gene Frequency - genetics | Genetic Predisposition to Disease - genetics | Humans | Middle Aged | Adult | Female | Male | Aged | Interleukin-27 - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Index Medicus | Abridged Index Medicus | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text A phase I dose-escalation study of intravenous panobinostat in patients with lymphoma and solid tumors
by Sharma, Sunil and Beck, Joachim and Mita, Monica and Paul, Sofia and Woo, Margaret M and Squier, Margaret and Gadbaw, Brian and Prince, H Miles
Investigational New Drugs, ISSN 0167-6997, 8/2013, Volume 31, Issue 4, pp. 974 - 985
Purpose Panobinostat, a pan-deacetylase inhibitor, is a promising anti-cancer agent that increases acetylation of proteins associated with growth and survival... 
Panobinostat | Medicine & Public Health | DAC | Oncology | Pharmacology/Toxicology | DACi | Cancer | CRITERIA | ACETYLATION | T-CELL LYMPHOMA | HISTONE-DEACETYLASE INHIBITORS | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | CLINICAL-TRIALS | LBH589 | PHARMACOLOGY & PHARMACY | Demography | Humans | Hydroxamic Acids - adverse effects | Middle Aged | Histone Deacetylase Inhibitors - administration & dosage | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Indoles - administration & dosage | Dose-Response Relationship, Drug | Histone Deacetylase Inhibitors - pharmacokinetics | Lymphoma - drug therapy | Antineoplastic Agents - adverse effects | Hydroxamic Acids - administration & dosage | Female | Antineoplastic Agents - pharmacokinetics | Acetylation | Treatment Outcome | Hydroxamic Acids - pharmacokinetics | Administration, Intravenous | Maximum Tolerated Dose | Indoles - adverse effects | Hydroxamic Acids - therapeutic use | Indoles - pharmacokinetics | Indoles - therapeutic use | Aged | Histone Deacetylase Inhibitors - therapeutic use | Histone Deacetylase Inhibitors - adverse effects | Antimitotic agents | Complications and side effects | Dosage and administration | Lymphomas | Research | Antineoplastic agents | Drug therapy | Tumors | Studies | Cancer therapies | Patients | Pharmaceutical sciences | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Population pharmacokinetics of intravenous and oral panobinostat in patients with hematologic and solid tumors
by Savelieva, Marina and Woo, Margaret M and Schran, Horst and Mu, Song and Nedelman, Jerry and Capdeville, Renaud
European Journal of Clinical Pharmacology, ISSN 0031-6970, 6/2015, Volume 71, Issue 6, pp. 663 - 672
The study aimed to characterize the population pharmacokinetics of panobinostat, a pan-deacetylase inhibitor that has demonstrated efficacy in combination with... 
Panobinostat | Population pharmacokinetics | Biomedicine | Pan-deacetylase inhibitor | Pan-DACi | Bioavailability | Pharmacology/Toxicology | Modeling | ADVANCED CANCER | MULTICENTER | SAFETY | OPEN-LABEL | DOSE-ESCALATION | PHASE-II TRIAL | LBH589 | LYMPHOMA | MALIGNANCIES | PHARMACOLOGY & PHARMACY | Administration, Oral | Area Under Curve | Humans | Middle Aged | Biological Availability | Male | Metabolic Clearance Rate | Antineoplastic Agents - administration & dosage | Indoles - administration & dosage | Hydroxamic Acids - pharmacokinetics | Young Adult | Adolescent | Aged, 80 and over | Hematologic Neoplasms - drug therapy | Hydroxamic Acids - administration & dosage | Adult | Female | Indoles - pharmacokinetics | Aged | Antineoplastic Agents - pharmacokinetics | Infusions, Intravenous | Care and treatment | Corticosteroids | Analysis | Liver | Tumors | Pharmacology | Index Medicus | Clinical Trial
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text A phase I study of oral panobinostat alone and in combination with docetaxel in patients with castration-resistant prostate cancer
by Rathkopf, Dana and Wong, Bryan Y and Ross, Robert W and Anand, Aseem and Tanaka, Erika and Woo, Margaret M and Hu, Jing and Dzik-Jurasz, Andy and Yang, Wei and Scher, Howard I
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 5/2010, Volume 66, Issue 1, pp. 181 - 189
Histone deacetylase inhibitors have demonstrated anticancer activity against a range of tumors. We aimed to define the maximum tolerated dose, toxicity,... 
Panobinostat | Histone deacetylase inhibitor | Medicine & Public Health | Docetaxel | Oncology | Cancer Research | Castration-resistant | Pharmacology/Toxicology | Prostate cancer | ANDROGEN RECEPTOR | SUBEROYLANILIDE HYDROXAMIC ACID | REPRODUCIBILITY | CIRCULATING TUMOR-CELLS | ONCOLOGY | RECOMMENDATIONS | CLINICAL-TRIALS | END-POINTS | MALIGNANCIES | PHARMACOLOGY & PHARMACY | PET | Humans | Hydroxamic Acids - adverse effects | Middle Aged | Histone Deacetylase Inhibitors - administration & dosage | Drug Resistance, Neoplasm | Male | Positron-Emission Tomography | Histone Deacetylase Inhibitors - pharmacokinetics | Neoplasm Metastasis | Aged, 80 and over | Hydroxamic Acids - administration & dosage | Prostate-Specific Antigen - drug effects | Prostatic Neoplasms - diagnostic imaging | Indoles | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Neoplastic Cells, Circulating - drug effects | Administration, Oral | Treatment Outcome | Prostate-Specific Antigen - blood | Histones - blood | Hydroxamic Acids - pharmacokinetics | Taxoids - administration & dosage | Acetylation - drug effects | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Fluorodeoxyglucose F18 | Aged | Histone Deacetylase Inhibitors - adverse effects | Medical colleges | Antigens | Care and treatment | Oncology, Experimental | Research | DNA binding proteins | Antineoplastic agents | Antimitotic agents | Cancer patients | Histones | Injuries | Tumors | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Therapeutic advantage of anti‐VAP‐1 over anti‐α4 integrin antibody in concanavalin a‐induced hepatitis
by Lee, Woo‐Yong and Salmi, Marko and Kelly, Margaret M and Jalkanen, Sirpa and Kubes, Paul
Hepatology, ISSN 0270-9139, 10/2013, Volume 58, Issue 4, pp. 1413 - 1423
Hepatitis induced by concanavalin A (Con A) in mice is well known to be a T‐lymphocyte‐mediated injury. It has been reported that T helper (Th)1 and Th2... 
Cell Adhesion Molecules - genetics | Liver - pathology | Male | Alanine Transaminase - blood | Cell Adhesion Molecules - immunology | CD4-Positive T-Lymphocytes - pathology | T-Lymphocytes, Regulatory - pathology | Dose-Response Relationship, Drug | Amine Oxidase (Copper-Containing) - immunology | Chemical and Drug Induced Liver Injury - pathology | Antibodies, Anti-Idiotypic - therapeutic use | Amine Oxidase (Copper-Containing) - genetics | Disease Models, Animal | Amine Oxidase (Copper-Containing) - deficiency | Liver - metabolism | Mice, Inbred C57BL | Cell Adhesion Molecules - deficiency | Antibodies, Anti-Idiotypic - immunology | Treatment Outcome | Integrin alpha4 - immunology | Mice, Knockout | Animals | Chemical and Drug Induced Liver Injury - metabolism | Concanavalin A - adverse effects | Chemical and Drug Induced Liver Injury - drug therapy | Mice | Mice, Inbred BALB C | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights