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The Journal of Pathology, ISSN 0022-3417, 06/2019, Volume 248, Issue 2, pp. 131 - 141
The remarkable aggressiveness of pancreatic cancer has never been fully explained. Although clearly multifactorial, we postulate that venous invasion, a... 
pancreatic cancer | vein | tumor immune microenvironment | pancreas | pancreas cancer | prognosis | venous invasion | DUCTAL ADENOCARCINOMA | PERINEURAL INVASION | TO-MESENCHYMAL-TRANSITION | LONG-TERM SURVIVAL | VASCULAR INVASION | NEURAL INVASION | PATHOLOGY | PAPILLARY MUCINOUS NEOPLASMS | BREAST-CANCER | ONCOLOGY | VOLUME DOUBLING TIME | Pancreatic cancer | Organs | Cancer
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 17955 - 10
We compared the cranial base of newborn Pax7-deficient and wildtype mice using a computational shape modeling technology called particle-based modeling (PBM).... 
EVOLUTION | MORPHOMETRICS | MODELS | PAX7 | MULTIDISCIPLINARY SCIENCES | ARDIPITHECUS-RAMIDUS | PHENOTYPE | Cell lineage | Genetic control | Morphology | Rodents | Computer applications
Journal Article
Human Pathology, ISSN 0046-8177, 02/2018, Volume 72, pp. 127 - 134
Patients with hepatocellular carcinoma (HCC) frequently have multiple anatomically distinct tumors. In these patients, multifocal HCC could represent... 
Multicentric carcinogenesis | Next-generation sequencing | Sanger sequencing | Multifocal hepatocellular carcinoma | Intrahepatic metastasis | Liver cancer | Pathology | Mutation | Metastasis | Tumors | Index Medicus
Journal Article
by Okbay, Aysu and Baselmans, B.M.L and Neve, Jan-Emmanuel and Turley, Patrick and Nivard, Michel and Fontana, M.A and Meddens, S.F.W and Linnér, R.K and Rietveld, C.A and Derringer, J and Gratten, Jacob and Lee, James J and Liu, J.Z and Vlaming, Ronald and SAhluwalia, T and Buchwald, J and Cavadino, Alana and Frazier-Wood, Alexis C and Furlotte, N.A and Garfield, V and Geisel, M.H and Gonzalez, Juan R and Haitjema, S and Karlsson, Robert and Der Laan, S.W and Ladwig, Karl-Heinz and Lahti, Jari and Lee, Sven and Lind, Penelope and Liu, T and Matteson, L and Mihailov, Evelin and Miller, Mike and CMinica, C and MNolte, I and Mook-Kanamori, Dennis and Most, Peter and Oldmeadow, Christopher and Qian, Yong and Raitakari, Olli and Rawal, R and Realo, A and Rueedi, R and Schmidt, B and Smith, Albert Vernon and Stergiakouli, Evangelia and Tanaka, Toshiko and Taylor, Kent and Wedenoja, J and Wellmann, J and Westra, Harm-Jan and MWillems, S and Zhao, W and Study, LifeLines Cohort and Amin, Najaf and Bakshi, A and Boyle, Patricia and Cherney, S and Cox, S.R and Davies, Gail and Davis, Oliver S and Ding, Jun and Direk, Nese and Eibich, P and Emeny, Rebecca and Fatemifar, G and Faul, J.D and Ferrucci, Luigi and Forstner, Aneas and Gieger, Christian and Gupta, R and Harris, Tamara B and Harris, Juliette and Holliday, Elizabeth and Hottenga, Jouke Jan and Jager, Philip and Kaakinen, Marika and Kajantie, Eero and Karhunen, V and Kolcic, Ivana and Kumari, Meena and Launer, Lenore and Franke, Lude and Li-Gao, R and Koini, M and Loukola, Anu and Marques-Vidal, P and Montgomery, Grant and Mosing, Miriam and Paternoster, Lavinia and Pattie, Alison and Petrovic, Katja and Pulkki-R'back, L and Quaye, Lydia and R'ikkönen, K and Rudan, Igor and Scott, Rodney and Smith, Jennifer A and Sutin, A.R and Trzaskowski, M and ... and LifeLines Cohort Study
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 624 - 633
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 02/2019, Volume 37, Issue 2, pp. 299 - 307
Journal Article
Modern Pathology, ISSN 0893-3952, 2018, Volume 32, Issue 5, pp. 659 - 665
This study aimed to understand the biology of pancreatic ductal adenocarcinoma that arises in the remnant pancreas after surgical resection of a primary... 
IMPACT | EVOLUTION | PATHOLOGY | DUCTAL ADENOCARCINOMA | CARCINOMA | Adenocarcinoma | Next-generation sequencing | Pancreas | Pancreatic cancer | Cancer
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 26, pp. 2509 - 2520
Persons with mismatch repair–deficient tumors are more likely than persons with mismatch repair–proficient tumors to benefit from pembrolizumab — which... 
MEDICINE, GENERAL & INTERNAL | COLORECTAL CARCINOMAS | ANTI-PD-L1 ANTIBODY | SAFETY | MICROSATELLITE INSTABILITY | DNA | GERMLINE MUTATIONS | PREDISPOSE | CLINICAL ACTIVITY | CANCER | LYMPHOCYTES | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Colorectal Neoplasms - genetics | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease-Free Survival | Neoplasm Metastasis - genetics | Neoplasm Metastasis - drug therapy | Antineoplastic Agents - adverse effects | Colorectal Neoplasms - drug therapy | DNA Mismatch Repair | Adult | Female | Adenocarcinoma - genetics | Aged | Colorectal Neoplasms - pathology | Antibody diversity | Carcinoma | Genetic disorders | Analysis | Research | Risk factors | Cancer | Tumors | Antigens | Yeast | PD-1 protein | Colorectal carcinoma | Body weight | Colorectal cancer | Autoantigens | DNA repair | Survival | Metastases | Pembrolizumab | Immune checkpoint | Immunogenicity | Mismatch repair | Death | Mutation | Genetic recombination | Cancer therapies | Drug dosages | Immune system | Medical research | Melanoma | Patients | Studies | Hypotheses | Pancreatic cancer | Epigenetics | Biomarkers | Ligands | Index Medicus | Abridged Index Medicus
Journal Article
Advances In Anatomic Pathology, ISSN 1072-4109, 01/2019, Volume 26, Issue 1, pp. 31 - 39
Although pathologic lesions in the pancreas are 3-dimensional (3D) complex structures, we currently use thin 2D hematoxylin and eosin stained slides to study... 
Journal Article