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Abstracts of the HIV Research for Prevention Meeting, HIVR4P, 21-25 October, 2018, Madrid
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2018, Volume 34, Issue S1, pp. 1 - 407
Journal Article
Medicine, ISSN 1357-3039, 05/2019, Volume 47, Issue 5, pp. 263 - 268
Gastro-oesophageal reflux disease (GORD) is a common disorder with an increasing prevalence in th UK. The presence of a hiatus hernia is the strongest risk...
proton pump inhibitors | Ambulatory reflux testing | MRCP | hiatus hernia | gastro-oesophageal reflux disease
proton pump inhibitors | Ambulatory reflux testing | MRCP | hiatus hernia | gastro-oesophageal reflux disease
Journal Article
Gut, ISSN 0017-5749, 09/2013, Volume 62, Issue 9, pp. 1256 - 1261
Objective Patients with non-erosive reflux disease (NERD) have impaired oesophageal mucosal integrity (dilated intercellular spaces). Oesophageal mucosal...
erosive oesophagitis | DETERMINANTS | Gastro-oesophageal reflux disease | oesophageal reflux | acid-related diseases | DILATED INTERCELLULAR SPACES | PATHOGENESIS | oesophageal mucosa | oesophageal impedance | endoscopic ultrasonography | EPITHELIUM | mucosal barrier | IMPEDANCE | anti-reflux therapy | FUNCTIONAL HEARTBURN | EXPOSURE | gastrointestinal motility | neurogastroenterology | dysphagia | adenocarcinoma | CLASSIFICATION | oesophageal physiology | PERCEPTION | Barrett's oesophagus | GASTROENTEROLOGY & HEPATOLOGY | Severity of Illness Index | Gastroesophageal Reflux - diagnosis | Heartburn - physiopathology | Esophageal pH Monitoring | Gastroesophageal Reflux - physiopathology | Humans | Middle Aged | Heartburn - diagnosis | Male | Symptom Assessment - methods | Electric Impedance | Extracellular Space | Recovery of Function | Esophagus - physiopathology | Esophagus - pathology | Gastroesophageal Reflux - complications | Mucous Membrane - physiopathology | Time Factors | Heartburn - etiology | Female | Acids - pharmacology | Hydrogen-Ion Concentration | Gastroesophageal reflux | Studies | Genotype & phenotype | Acids | Microscopy | Biopsy | Rodents | Permeability | Endoscopy | Mucous membrane
erosive oesophagitis | DETERMINANTS | Gastro-oesophageal reflux disease | oesophageal reflux | acid-related diseases | DILATED INTERCELLULAR SPACES | PATHOGENESIS | oesophageal mucosa | oesophageal impedance | endoscopic ultrasonography | EPITHELIUM | mucosal barrier | IMPEDANCE | anti-reflux therapy | FUNCTIONAL HEARTBURN | EXPOSURE | gastrointestinal motility | neurogastroenterology | dysphagia | adenocarcinoma | CLASSIFICATION | oesophageal physiology | PERCEPTION | Barrett's oesophagus | GASTROENTEROLOGY & HEPATOLOGY | Severity of Illness Index | Gastroesophageal Reflux - diagnosis | Heartburn - physiopathology | Esophageal pH Monitoring | Gastroesophageal Reflux - physiopathology | Humans | Middle Aged | Heartburn - diagnosis | Male | Symptom Assessment - methods | Electric Impedance | Extracellular Space | Recovery of Function | Esophagus - physiopathology | Esophagus - pathology | Gastroesophageal Reflux - complications | Mucous Membrane - physiopathology | Time Factors | Heartburn - etiology | Female | Acids - pharmacology | Hydrogen-Ion Concentration | Gastroesophageal reflux | Studies | Genotype & phenotype | Acids | Microscopy | Biopsy | Rodents | Permeability | Endoscopy | Mucous membrane
Journal Article
Gut, ISSN 0017-5749, 05/2014, Volume 63, Issue 5, pp. 705 - 706
When the mucosa is exposed to solutions containing acid and bile acids, the TEER falls and the magnitude of such reduction correlates with permeability to...
DILATED INTERCELLULAR SPACES | PROTECTION | GASTROENTEROLOGY & HEPATOLOGY | INTEGRITY | EXPOSURE | Tight Junctions - metabolism | Animals | Humans | NF-E2-Related Factor 2 - metabolism | Gastroesophageal Reflux - etiology | Esophagus - metabolism | Male | NF-E2-Related Factor 2 - deficiency | Acids | Small intestine | Rodents | Mucous membrane
DILATED INTERCELLULAR SPACES | PROTECTION | GASTROENTEROLOGY & HEPATOLOGY | INTEGRITY | EXPOSURE | Tight Junctions - metabolism | Animals | Humans | NF-E2-Related Factor 2 - metabolism | Gastroesophageal Reflux - etiology | Esophagus - metabolism | Male | NF-E2-Related Factor 2 - deficiency | Acids | Small intestine | Rodents | Mucous membrane
Journal Article
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 2014, Volume 11, Issue 7, pp. 397 - 398
Increased gastro-oesophageal reflux (GER) is described as a very common problem in infants. Loots et al. investigated the effect of the left lateral position...
Infant | Posture - physiology | Gastroesophageal Reflux - physiopathology | Humans
Infant | Posture - physiology | Gastroesophageal Reflux - physiopathology | Humans
Journal Article
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 09/2016, Volume 13, Issue 9, pp. 529 - 542
Detailed investigations and objective measurements in patients with symptoms of gastro-oesophageal reflux should be performed with the intent of making the...
CHRONIC POSTERIOR LARYNGITIS | COMMUNITY-ACQUIRED PNEUMONIA | GASTROESOPHAGEAL-REFLUX DISEASE | PROTON-PUMP INHIBITOR | RANDOMIZED CLINICAL-TRIAL | ESOPHAGEAL PH-IMPEDANCE | DIFFICILE-ASSOCIATED DISEASE | ACUTE INTERSTITIAL NEPHRITIS | GASTROENTEROLOGY & HEPATOLOGY | SUSPECTED EXTRAESOPHAGEAL REFLUX | MULTICHANNEL INTRALUMINAL IMPEDANCE | Gastroesophageal Reflux - therapy | Phenotype | Algorithms | Gastroesophageal Reflux - diagnosis | Humans | Adult | Unnecessary Procedures | Electric Impedance | Gastroesophageal Reflux - genetics | Proton Pump Inhibitors - therapeutic use | Child | Hydrogen-Ion Concentration | Gastroesophageal reflux | Evaluation | Care and treatment | Practice guidelines (Medicine) | Medical care | Genetic aspects | Diagnosis | Identification and classification | Health aspects | Quality management
CHRONIC POSTERIOR LARYNGITIS | COMMUNITY-ACQUIRED PNEUMONIA | GASTROESOPHAGEAL-REFLUX DISEASE | PROTON-PUMP INHIBITOR | RANDOMIZED CLINICAL-TRIAL | ESOPHAGEAL PH-IMPEDANCE | DIFFICILE-ASSOCIATED DISEASE | ACUTE INTERSTITIAL NEPHRITIS | GASTROENTEROLOGY & HEPATOLOGY | SUSPECTED EXTRAESOPHAGEAL REFLUX | MULTICHANNEL INTRALUMINAL IMPEDANCE | Gastroesophageal Reflux - therapy | Phenotype | Algorithms | Gastroesophageal Reflux - diagnosis | Humans | Adult | Unnecessary Procedures | Electric Impedance | Gastroesophageal Reflux - genetics | Proton Pump Inhibitors - therapeutic use | Child | Hydrogen-Ion Concentration | Gastroesophageal reflux | Evaluation | Care and treatment | Practice guidelines (Medicine) | Medical care | Genetic aspects | Diagnosis | Identification and classification | Health aspects | Quality management
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 04/2013, Volume 108, Issue 4, pp. 535 - 543
OBJECTIVES: Intact esophageal mucosal integrity is essential to prevent symptoms during gastroesophageal reflux events. Approximately 70% of patients with...
ACID REFLUX | GASTROESOPHAGEAL-REFLUX | NONEROSIVE REFLUX DISEASE | GASTRIC-ACID | IMPEDANCE | SODIUM ALGINATE SUSPENSIONS | PROTON PUMP INHIBITORS | DILATED INTERCELLULAR SPACES | GASTROENTEROLOGY & HEPATOLOGY | FUNCTIONAL HEARTBURN | BILE-ACIDS | Esophagus - drug effects | Esophageal pH Monitoring | Humans | Middle Aged | Male | Electric Impedance | Gastroesophageal Reflux - prevention & control | Case-Control Studies | Feasibility Studies | Heartburn - complications | Bile Acids and Salts - adverse effects | Young Adult | Alginates - administration & dosage | Biopsy | Esophagitis - prevention & control | Adult | Female | Aged | Mucous Membrane - drug effects | Administration, Topical
ACID REFLUX | GASTROESOPHAGEAL-REFLUX | NONEROSIVE REFLUX DISEASE | GASTRIC-ACID | IMPEDANCE | SODIUM ALGINATE SUSPENSIONS | PROTON PUMP INHIBITORS | DILATED INTERCELLULAR SPACES | GASTROENTEROLOGY & HEPATOLOGY | FUNCTIONAL HEARTBURN | BILE-ACIDS | Esophagus - drug effects | Esophageal pH Monitoring | Humans | Middle Aged | Male | Electric Impedance | Gastroesophageal Reflux - prevention & control | Case-Control Studies | Feasibility Studies | Heartburn - complications | Bile Acids and Salts - adverse effects | Young Adult | Alginates - administration & dosage | Biopsy | Esophagitis - prevention & control | Adult | Female | Aged | Mucous Membrane - drug effects | Administration, Topical
Journal Article
IEEE/ACM Transactions on Audio, Speech and Language Processing (TASLP), ISSN 2329-9290, 11/2016, Volume 24, Issue 11, pp. 2146 - 2157
Recurrent neural network language models RNNLMs are becoming increasingly popular for a range of applications including automatic speech recognition. An...
Vocabulary | Recurrent neural networks | noise contrastive | recurrent neural network | Estimation | Artificial neural networks | History | GPU | Training | variance regularisation | speech recognition | pipelined training | Computer architecture | Speech | language models | ACOUSTICS | ENGINEERING, ELECTRICAL & ELECTRONIC | Voice recognition | Neural networks | Architecture | Computation | Graphics processing units | Mathematical models | Central processing units | Automatic speech recognition
Vocabulary | Recurrent neural networks | noise contrastive | recurrent neural network | Estimation | Artificial neural networks | History | GPU | Training | variance regularisation | speech recognition | pipelined training | Computer architecture | Speech | language models | ACOUSTICS | ENGINEERING, ELECTRICAL & ELECTRONIC | Voice recognition | Neural networks | Architecture | Computation | Graphics processing units | Mathematical models | Central processing units | Automatic speech recognition
Journal Article
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12846 - 12846
Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may provide new...
INSULIN | REPLACEMENT | ENDOMETRIAL CANCER-RISK | THERAPY | DATABASE | MULTIDISCIPLINARY SCIENCES | GROWTH | IMATINIB | ALPHA | ESTROGEN-RECEPTOR | DISCOVERY
INSULIN | REPLACEMENT | ENDOMETRIAL CANCER-RISK | THERAPY | DATABASE | MULTIDISCIPLINARY SCIENCES | GROWTH | IMATINIB | ALPHA | ESTROGEN-RECEPTOR | DISCOVERY
Journal Article
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-294 - S-294
Journal Article
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-292 - S-293
Journal Article
Journal of Clinical Gastroenterology, ISSN 0192-0790, 01/2014, Volume 48, Issue 1, pp. 6 - 12
Gastroesophageal reflux disease, especially when refractory to standard therapy, remains a significant clinical problem. Although symptom pathogenesis in...
mucosal integrity | GERD | impedance | dilated intercellular spaces | nonerosive reflux disease | transepithelial electrical resistance | ACID REFLUX | HIATUS-HERNIA | HEARTBURN | INJURY | PROTON PUMP INHIBITORS | E-CADHERIN | TIGHT JUNCTIONS | PARACELLULAR CONDUCTANCE | POTENTIAL DIFFERENCE | GASTROENTEROLOGY & HEPATOLOGY | Esophagus - pathology | Extracellular Space - metabolism | Mucous Membrane - pathology | Animals | Heartburn - etiology | Gastroesophageal Reflux - pathology | Humans | Permeability
mucosal integrity | GERD | impedance | dilated intercellular spaces | nonerosive reflux disease | transepithelial electrical resistance | ACID REFLUX | HIATUS-HERNIA | HEARTBURN | INJURY | PROTON PUMP INHIBITORS | E-CADHERIN | TIGHT JUNCTIONS | PARACELLULAR CONDUCTANCE | POTENTIAL DIFFERENCE | GASTROENTEROLOGY & HEPATOLOGY | Esophagus - pathology | Extracellular Space - metabolism | Mucous Membrane - pathology | Animals | Heartburn - etiology | Gastroesophageal Reflux - pathology | Humans | Permeability
Journal Article
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Two efficient lattice rescoring methods using recurrent neural network language models
IEEE/ACM Transactions on Audio, Speech and Language Processing (TASLP), ISSN 2329-9290, 08/2016, Volume 24, Issue 8, pp. 1438 - 1449
An important part of the language modelling problem for automatic speech recognition (ASR) systems, and many other related applications, is to appropriately...
language model | lattice rescoring | recurrent neural network | speech recognition | Context | Training | Vocabulary | Recurrent neural networks | Lattices | History | Context modeling | ACOUSTICS | Language model | ERROR | SPEECH | ENGINEERING, ELECTRICAL & ELECTRONIC | Voice recognition | Neural networks | Networks | State of the art | Lists | Mathematical analysis | Mandarins | Vectors (mathematics)
language model | lattice rescoring | recurrent neural network | speech recognition | Context | Training | Vocabulary | Recurrent neural networks | Lattices | History | Context modeling | ACOUSTICS | Language model | ERROR | SPEECH | ENGINEERING, ELECTRICAL & ELECTRONIC | Voice recognition | Neural networks | Networks | State of the art | Lists | Mathematical analysis | Mandarins | Vectors (mathematics)
Journal Article
Neurogastroenterology & Motility, ISSN 1350-1925, 09/2019, Volume 31, Issue 9, pp. e13667 - n/a
Background Mucosal innervation in non‐erosive reflux disease (NERD; pathological esophageal acid exposure, normal macroscopic mucosa) is clearly distinct from...
oesophageal mucosa innervation | non‐erosive gastroesophageal reflux disease | functional heartburn | non-erosive gastroesophageal reflux disease | GASTROENTEROLOGY & HEPATOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | HYPERSENSITIVITY | Gastroesophageal reflux | Heartburn | Heart | Calcitonin gene-related peptide | Pain perception | Innervation | Mucosa | Nerves | Barrett's esophagus | Sensory neurons | Esophagitis | Esophagus | Fibers
oesophageal mucosa innervation | non‐erosive gastroesophageal reflux disease | functional heartburn | non-erosive gastroesophageal reflux disease | GASTROENTEROLOGY & HEPATOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | HYPERSENSITIVITY | Gastroesophageal reflux | Heartburn | Heart | Calcitonin gene-related peptide | Pain perception | Innervation | Mucosa | Nerves | Barrett's esophagus | Sensory neurons | Esophagitis | Esophagus | Fibers
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 11/2019, p. 1
OBJECTIVES:Up to 40% of children presenting with reflux symptoms do not respond to standard medical interventions. In adults, 20% of patients presenting with...
Journal Article
Gut, ISSN 0017-5749, 09/2013, Volume 62, Issue 9, p. 1256
Journal Article
Best Practice & Research Clinical Gastroenterology, ISSN 1521-6918, 2010, Volume 24, Issue 6, pp. 861 - 871
The pathogenesis of gastrointestinal reflux disease is multifactoral. Integral to the disease process is the refluxate itself. The characteristics and...
Oesophagitis | Non-erosive reflux disease | Acid | Bile acids | Refluxate | Gastro-oesophageal reflux disease | Oesophageal adenocarcinoma | Barrett’s oesophagus | Heartburn | Barrett's oesophagus | DUODENOGASTROESOPHAGEAL REFLUX | PROTON PUMP INHIBITORS | BARRETTS-ESOPHAGUS | Gastro oesophageal reflux disease | NONACID REFLUX | ESOPHAGEAL ACID CLEARANCE | GASTROESOPHAGEAL-REFLUX | GASTRIC-ACID | BILE REFLUX | DISEASE | Barrett oesophagus | PROXIMAL EXTENT | GASTROENTEROLOGY & HEPATOLOGY | Non erosive reflux disease | Esophageal Neoplasms - etiology | Severity of Illness Index | Barrett Esophagus - metabolism | Gastroesophageal Reflux - metabolism | Prognosis | Risk Assessment | Adenocarcinoma - etiology | Gastroesophageal Reflux - physiopathology | Humans | Risk Factors | Gastroesophageal Reflux - etiology | Bile Acids and Salts - metabolism | Barrett Esophagus - etiology | Pepsin A - metabolism | Esophagitis - metabolism | Esophagitis - etiology | Disease Progression | Gastric Acid - secretion | Adenocarcinoma - metabolism | Esophageal Neoplasms - metabolism | Gastric Acid - metabolism | Physiological aspects
Oesophagitis | Non-erosive reflux disease | Acid | Bile acids | Refluxate | Gastro-oesophageal reflux disease | Oesophageal adenocarcinoma | Barrett’s oesophagus | Heartburn | Barrett's oesophagus | DUODENOGASTROESOPHAGEAL REFLUX | PROTON PUMP INHIBITORS | BARRETTS-ESOPHAGUS | Gastro oesophageal reflux disease | NONACID REFLUX | ESOPHAGEAL ACID CLEARANCE | GASTROESOPHAGEAL-REFLUX | GASTRIC-ACID | BILE REFLUX | DISEASE | Barrett oesophagus | PROXIMAL EXTENT | GASTROENTEROLOGY & HEPATOLOGY | Non erosive reflux disease | Esophageal Neoplasms - etiology | Severity of Illness Index | Barrett Esophagus - metabolism | Gastroesophageal Reflux - metabolism | Prognosis | Risk Assessment | Adenocarcinoma - etiology | Gastroesophageal Reflux - physiopathology | Humans | Risk Factors | Gastroesophageal Reflux - etiology | Bile Acids and Salts - metabolism | Barrett Esophagus - etiology | Pepsin A - metabolism | Esophagitis - metabolism | Esophagitis - etiology | Disease Progression | Gastric Acid - secretion | Adenocarcinoma - metabolism | Esophageal Neoplasms - metabolism | Gastric Acid - metabolism | Physiological aspects
Journal Article
Best Practice & Research: Clinical Gastroenterology, ISSN 1521-6918, 2013, Volume 27, Issue 3, pp. 455 - 467
Abstract Gastroesophageal reflux disease (GERD) is a prevalent problem resulting in a high level of healthcare consultation and expenditure in the Western...
Gastroenterology and Hepatology | Endoscopic GERD therapy | Reflux inhibitors | Visceral hypersensitivity | Refractory disease | Gastroesophageal reflux disease | GERD therapy | Endoscopic | VISCERAL PAIN HYPERSENSITIVITY | RANDOMIZED CLINICAL-TRIAL | LONG-TERM FAILURE | TRANSORAL INCISIONLESS FUNDOPLICATION | ESOMEPRAZOLE 40 MG | SHAM-CONTROLLED TRIAL | GASTROESOPHAGEAL-REFLUX DISEASE | PROTON PUMP INHIBITOR | LOWER ESOPHAGEAL SPHINCTER | PROSPECTIVE FOLLOW-UP | GASTROENTEROLOGY & HEPATOLOGY | Gastroesophageal Reflux - surgery | Fundoplication - methods | Gastroesophageal Reflux - drug therapy | Proton Pump Inhibitors - therapeutic use | Deglutition Disorders - surgery | Humans | Gastroesophageal reflux | Health aspects | Care and treatment
Gastroenterology and Hepatology | Endoscopic GERD therapy | Reflux inhibitors | Visceral hypersensitivity | Refractory disease | Gastroesophageal reflux disease | GERD therapy | Endoscopic | VISCERAL PAIN HYPERSENSITIVITY | RANDOMIZED CLINICAL-TRIAL | LONG-TERM FAILURE | TRANSORAL INCISIONLESS FUNDOPLICATION | ESOMEPRAZOLE 40 MG | SHAM-CONTROLLED TRIAL | GASTROESOPHAGEAL-REFLUX DISEASE | PROTON PUMP INHIBITOR | LOWER ESOPHAGEAL SPHINCTER | PROSPECTIVE FOLLOW-UP | GASTROENTEROLOGY & HEPATOLOGY | Gastroesophageal Reflux - surgery | Fundoplication - methods | Gastroesophageal Reflux - drug therapy | Proton Pump Inhibitors - therapeutic use | Deglutition Disorders - surgery | Humans | Gastroesophageal reflux | Health aspects | Care and treatment
Journal Article