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Nucleic Acids Research, ISSN 0305-1048, 11/2019
Abstract RNA:5-methylcytosine (m5C) methyltransferases are currently the focus of intense research following a series of high-profile reports documenting their... 
Journal Article
CHEMICAL SCIENCE, ISSN 2041-6520, 2015, Volume 6, Issue 1, pp. 112 - 122
The AlkB family of nucleic acid demethylases are of intense biological and medical interest because of their roles in nucleic acid repair and epigenetic... 
RNA DEMETHYLASE | OBESITY-ASSOCIATED FTO | OXIDATIVE DEMETHYLATION | ESCHERICHIA-COLI | CRYSTAL-STRUCTURES | REPAIR ENZYME ALKB | HISTONE DEMETHYLASES | NUCLEIC-ACID DEMETHYLASE | CHEMISTRY, MULTIDISCIPLINARY | SUBSTRATE RECOGNITION | DNA DEMETHYLATION
Journal Article
CHEMICAL SCIENCE, ISSN 2041-6520, 09/2018, Volume 9, Issue 36, p. 7174
N-6-Methyladenosine (m(6)A) is one of the most abundant epigenetic modifications on mRNA. It is dynamically regulated by the m(6)A demethylases FTO and ALKBH5,... 
OBESITY-ASSOCIATED FTO | STEM-CELLS | ALKBH5 | MESSENGER-RNA | GENE | STRUCTURAL BASIS | STABILITY | MA RNA METHYLATION | NUCLEAR-RNA | CHEMISTRY, MULTIDISCIPLINARY | ALKYLATION DAMAGE
Journal Article
EMBO reports, ISSN 1469-221X, 05/2011, Volume 12, Issue 5, pp. 463 - 469
Journal Article
Journal Article
Chemistry, an Asian journal, 06/2018
Dynamic combinatorial chemistry (DCC) is a powerful supramolecular approach for discovering ligands for biomolecules. To date, most, if not all,... 
Journal Article
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 04/2017, Volume 12, pp. 2759 - 2767
Journal Article
Chemistry – An Asian Journal, ISSN 1861-4728, 10/2018, Volume 13, Issue 19, pp. 2740 - 2740
A multi‐protein differential scanning fluorimetry (DSF) strategy is reported. This strategy uses a thermal tag to exclusively fine‐tune the melting temperature... 
inhibitors | dynamic combinatorial chemistry | drug discovery | proteins | epigenetics
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 04/2016, Volume 52, Issue 36, pp. 6181 - 6184
We describe a novel methylation-sensitive nucleic acid (RNA) probe which switches conformation according to its methylation status. When combined with a... 
Scanning | Nucleic acids | Ribonucleic acids | Fluorimetry | Methylation | Switches
Journal Article
Chemical Communications, ISSN 1359-7345, 2016, Volume 52, Issue 36, pp. 6181 - 6184
Journal Article
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