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Genes and Development, ISSN 0890-9369, 08/2011, Volume 25, Issue 16, pp. 1680 - 1685
Journal Article
Current Biology, ISSN 0960-9822, 07/2019, Volume 29, Issue 14, p. 2339
The microtubule (MT) network is an essential regulator of insulin secretion from pancreatic [beta] cells, which is central to blood-sugar homeostasis. We find... 
Glucose metabolism | Developmental biology | Stem cells | Glucose | Insulin | Dextrose
Journal Article
Developmental Cell, ISSN 1534-5807, 09/2019, Volume 50, Issue 6, pp. 744 - 754.e4
Activating mutations in are nearly ubiquitous in human pancreatic cancer and initiate precancerous pancreatic intraepithelial neoplasia (PanINs) when induced... 
pancreatic cancer | Kras | differentiation | acinar cell | pancreas | Ptf1a | MAINTENANCE | INITIATION | ONCOGENIC KRAS | INFLAMMATION | SUSCEPTIBILITY LOCI | GENE-EXPRESSION | ACINAR-CELLS | DEVELOPMENTAL BIOLOGY | INTRAEPITHELIAL NEOPLASIA | CANCER | GENOME-WIDE ASSOCIATION | CELL BIOLOGY | Prevention | Molecular biology | Cell differentiation | Developmental biology | Analysis | Pancreatic cancer
Journal Article
Current Biology, ISSN 0960-9822, 07/2019, Volume 29, Issue 14, pp. 2339 - 2350.e5
The microtubule (MT) network is an essential regulator of insulin secretion from pancreatic β cells, which is central to blood-sugar homeostasis. We find that... 
pancreatic beta cells | insulin biogenesis | insulin granule | cytoskeleton | microtubule nucleation | dense-core granules | Golgi | insulin secretion | diabetes | EPAC | CYCLIC-AMP | TRANSPORT | PROTEIN | STIMULATION | CENTROSOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN GRANULE DYNAMICS | NUCLEATION | DYSFUNCTION | PROINSULIN SYNTHESIS | CAMP | CELL BIOLOGY
Journal Article
DIABETES, ISSN 0012-1797, 09/2019, Volume 68, Issue 9, pp. 1806 - 1818
Transcription factors positively and/or negatively impact gene expression by recruiting coregulatory factors, which interact through protein-protein binding.... 
IDENTITY | INSULIN GENE | DISTINCT | ENDOCRINOLOGY & METABOLISM | PAX6 | DIFFERENTIATION | MAFA | TRANSCRIPTION FACTOR | EXPRESSION | REVEALS | EXOCRINE
Journal Article
Molecular Metabolism, ISSN 2212-8778, 06/2019, Volume 24, pp. 80 - 97
Hundreds of missense mutations in the coding region of exist; however, if these mutations predispose to diabetes mellitus is unknown. In this study, we... 
Transactivation domain | PDX1 | PDX1-Bound genes | β-Cell differentiation | Insulin secretion | PROGENITORS | PANCREAS | beta-Cell differentiation | PLURIPOTENT STEM-CELLS | EPITHELIUM | GENES | ENDOCRINOLOGY & METABOLISM | TRANSCRIPTION FACTOR | EXPRESSION | ASSOCIATION | REVEALS
Journal Article
genesis, ISSN 1526-954X, 02/2000, Volume 26, Issue 2, pp. 139 - 142
Journal Article
Journal Article