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1. Full Text Retinal and optic nerve degeneration in liver X receptor [beta] knockout mice
by Xiao-yu, Song and Wan-fu, Wu and Gabbi, Chiara and Yu-bing, Dai and So, Mark and Chaurasiya, Surendra P and Wang, Li and Warner, Margaret and Jan-Ake, Gustafsson
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 08/2019, Volume 116, Issue 33, p. 16507
The retina is an extension of the brain. Like the brain, neurodegeneration of the retina occurs with age and is the cause of several retinal diseases including... 
Macular degeneration | Glaucoma | Autoimmunity | Viral antibodies | Aquaporins | Liver | Physiological aspects | Antibodies | Nervous system | Degeneration
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2. Full Text Transanal Total Mesorectal Excision: International Registry Results of the First 720 Cases
by Penna, Marta and Hompes, Roel and Arnold, Steve and Wynn, Greg and Austin, Ralph and Warusavitarne, Janina and Moran, Brendan and Hanna, George B and Mortensen, Neil J and Tekkis, Paris P and Albert, Matthew and Al Furajii, Hazar and Allison, Anew and Arezzo, Alberto and Aryal, Kamal and Ashraf, Shazad and Atallah, Sam and Baig, Khurrum and Baral, Jörg and Bemelman, Willem and Berger, David and Boni, Luigi and Bonjer, Jaap and Bordeianou, Liliana and Borreca, Dario and Buchs, Nicolas Christian and Cahill, Ronan and Campbell, Ken and Capolupo, Gabriella and Caricato, Marco and Cassinotti, Elisa and Chambers, William and Courtney, Edward Douglas and Cunningham, Christopher and Dalton, Stephan and Dawson, Robin and Delrio, Paolo and De Graaf, Eelco and De Paolis, Paolo and D'Hondt, Mathieu and D'Hoore, Ané and Doornebosch, Pascal and Erikson, Jens Ravn and Estévez-Schwarz, Lope and Fabryko, Miroslava and Fernández-Hevia, Maria and Knol, Joep and Sietses, Colin and Tuynman, Jurriaan and Velthuis, Simone and TaTME Registry Collaborative
Annals of Surgery, ISSN 0003-4932, 2017, Volume 266, Issue 1, pp. 111 - 117
Objective: This study aims to report short-term clinical and oncological outcomes from the international transanal Total Mesorectal Excision (taTME) registry... 
registry | risk factors | transanal total mesorectal excision | Surgery | poor histological outcomes | rectal cancer | SURGERY | RANDOMIZED CLINICAL-TRIAL | MARGIN INVOLVEMENT | PATHOLOGICAL OUTCOMES | LAPAROSCOPIC-ASSISTED RESECTION | LOW-RECTAL-CANCER | Humans | Middle Aged | Male | Young Adult | Intraoperative Complications | Minimally Invasive Surgical Procedures - adverse effects | Aged, 80 and over | Adult | Female | Neoadjuvant Therapy | Registries | Rectal Neoplasms - pathology | Rectum - surgery | Postoperative Complications | Digestive System Surgical Procedures - methods | Body Mass Index | Minimally Invasive Surgical Procedures - methods | Rectal Neoplasms - surgery | Risk Factors | Treatment Outcome | Digestive System Surgical Procedures - adverse effects | Adolescent | Anal Canal - surgery | Aged | Neoplasm Staging
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3. Full Text Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis
by Wan-fu Wu and Xin-jie Tan and Yu-bing Dai and Venkatesh Krishnan and Margaret Warner and Jan-Åke Gustafsson
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 9, pp. 3543 - 3548
A therapeutic goal in the treatment of certain CNS diseases, including multiple sclerosis, amyotrophic lateral sclerosis, and Parkinson disease, is to... 
T lymphocytes | Spinal cord | Multiple sclerosis | Nervous system diseases | Estrogen receptors | Parkinson disease | Central nervous system diseases | Agonists | White matter | Microglia | Glia | Nuclear receptor | MULTIDISCIPLINARY SCIENCES | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | glia | PROGRESSIVE MULTIPLE-SCLEROSIS | INFLAMMATION | IN-VIVO | NITRIC-OXIDE | DOUBLE-BLIND | nuclear receptor | GLATIRAMER ACETATE | PLACEBO-CONTROLLED TRIAL | NF-KAPPA-B | BRAIN | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Microglia - metabolism | Benzopyrans - therapeutic use | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - immunology | NF-kappa B - metabolism | Molecular Targeted Therapy | Estrogen Receptor beta - metabolism | T-Lymphocytes - metabolism | Spinal Cord - pathology | T-Lymphocytes - drug effects | Microglia - pathology | Estrogen Receptor alpha - metabolism | Female | T-Lymphocytes - pathology | Benzopyrans - pharmacology | Encephalomyelitis, Autoimmune, Experimental - pathology | Microglia - drug effects | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Spinal Cord - enzymology | Down-Regulation - drug effects | Animals | Encephalomyelitis, Autoimmune, Experimental - enzymology | Mice | Nitric Oxide Synthase Type II - metabolism | Biological Sciences
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4. Full Text Localization of Four Allergens in Artemisia Pollen by Immunofluorescent Antibodies
by Gao, Zhong-Shan and Fu, Wan-Yi and Zhao, Lan and Gao, Ling and Zhou, Jian-Ya and Gao, Bi-Yuan and Wu, Shandong and Versteeg, Serge A and Ferreira, Fatima and Gadermaier, Gabriele and van Ree, Ronald
International archives of allergy and immunology, ISSN 1018-2438, 04/2019, pp. 1 - 8
Background: Artemisia pollens have a high potential to induce allergic symptoms. Seven allergen components have been identified, but only Art v 7 has been... 
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5. Evaluation of a knee-kicker bumper design for reducing knee morbidity among carpet layers
by Wan-Fu Huang and Chih-Fu Wu
Applied Ergonomics, ISSN 0003-6870, 09/2012, Volume 43, Issue 5, p. 850
Carpet layers have a high prevalence of occupational knee morbidity. One of the main causes is that they need to frequently 'kick' the bumper on the rear end... 
Floor coverings | Ergonomics | Tools | Product design | Occupational accidents | Risk factors
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6. Full Text Interactions between uranium(vi) and phosphopeptide: experimental and theoretical investigationsElectronic supplementary information (ESI) available: ESI mass spectrum and fluorescence emission spectra as well as the total electron energy, MOs and NBO populations of U(vi)-P1 complexes. See DOI: 10.1039/c6dt03009b
by Wu, Qun-Yan and Zhai, Fu-Wan and Liu, Yang and Yuan, Li-Yong and Chai, Zhi-Fang and Shi, Wei-Qun
ISSN 1477-9226, 9/2016, Volume 45, Issue 38, pp. 14988 - 14997
Uranium is an essential actinide element in nuclear fuel cycles, and protein phosphorylation is one type of most important post-translational modifications. It... 
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7. Full Text Targeting ER beta in Macrophage Reduces Crown-like Structures in Adipose Tissue by Inhibiting Osteopontin and HIF-1 alpha
by Wang, L and Zhao, RP and Song, XY and Wu, WF
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 11
Proinflammatory processes in adipose tissue contribute to development of breast cancer and insulin resistance. Crown-like structures (CLS) are histologic... 
ESTROGEN-RECEPTOR-BETA | CELLS | OBESITY-INDUCED INFLAMMATION | MICROGLIA | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | MOUSE | DYSFUNCTION | HYPOXIA-INDUCIBLE FACTOR-1 | MAMMARY-GLAND INFLAMMATION | AROMATASE EXPRESSION | Hypoxia-inducible factors | Adipose tissue | Hydroxylase | Menopause | Central nervous system | Osteopontin | Breast cancer | Inflammation | Adipocytes | Macrophages | Insulin | Microglia | Monocytes | Cell activation | Insulin resistance | Agonists | Hypoxia | Prolyl hydroxylase
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8. Full Text Interactions between uranium(vi) and phosphopeptide: experimental and theoretical investigations
by Wu, Qun-Yan and Zhai, Fu-Wan and Liu, Yang and Yuan, Li-Yong and Chai, Zhi-Fang and Shi, Wei-Qun
Dalton transactions (Cambridge, England : 2003), ISSN 1477-9226, 10/2016, Volume 45, Issue 38, pp. 14988 - 14997
Uranium is an essential actinide element in nuclear fuel cycles, and protein phosphorylation is one type of most important post-translational modifications. It... 
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9. Full Text Interactions between uranium(VI) and phosphopeptide: Experimental and theoretical investigations
by Wu, Qun-Yan and Zhai, Fu-Wan and Liu, Yang and Yuan, Li-Yong and Chai, Zhi-Fang and Shi, Wei-Qun
Dalton Transactions, ISSN 1477-9226, 2016, Volume 45, Issue 38, pp. 14988 - 14997
Uranium is an essential actinide element in nuclear fuel cycles, and protein phosphorylation is one type of most important post-translational modifications. It... 
COORDINATION CHEMISTRY | ENERGY | RADICAL CATIONS | DENSITY-FUNCTIONAL THEORY | DFT CALCULATIONS | UO22 | URANYL BINDING | PEPTIDE | HIGHLY PHOSPHORYLATED PROTEIN | AQUEOUS-SOLUTION | CHEMISTRY, INORGANIC & NUCLEAR | Proteins | Fine structure | Phosphorylation | Peptides | Toxicity | Ionization | Tryptophan | In vivo methods and tests
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10. Full Text Ablation of Liver X receptors [alpha] and [beta] leads to spontaneous peripheral squamous cell lung cancer in mice
by Dai, Yu-bing and Miao, Yi-fei and Wu, Wan-fu and Li, Yu and D'Errico, Francesca and Su, Wen and Burns, Alan R and Huang, Bo and Maneix, Laure and Warner, Margaret and Gustafsson, Jan-Ake
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 07/2016, Volume 113, Issue 27, p. 7614
The etiology of peripheral squamous cell lung cancer (PSCCa) remains unknown. Here, we show that this condition spontaneously develops in mice in which the... 
Physiological aspects | Squamous cell carcinoma | Inflammation | Lung cancer
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11. Full Text Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate
by Wu, Wan-Fu and Maneix, Laure and Insunza, Jose and Nalvarte, Ivan and Antonson, Per and Kere, Juha and Yu, Nancy Yiu-Lin and Tohonen, Virpi and Katayama, Shintaro and Einarsdottir, Elisabet and Krjutskov, Kaarel and Dai, Yu-Bing and Huang, Bo and Su, Wen and Warner, Margaret and Gustafsson, Jan-Åke
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, pp. E3816 - E3822
As estrogen receptor beta(-/-) (ER beta(-/-)) mice age, the ventral prostate (VP) develops increased numbers of hyperplastic, fibroplastic lesions and... 
TGFβ | Cancer prevention | Nuclear receptor | Inflammation | DIFFERENTIAL EXPRESSION | cancer prevention | ER-BETA | MULTIDISCIPLINARY SCIENCES | FEMALE MICE | AGONIST LY500307 | PTEN | HYPERPLASIA | BREAST-CANCER CELLS | LIGANDS | inflammation | PATHWAY | GROWTH | nuclear receptor | TGF beta | Male | Nedd4 Ubiquitin Protein Ligases - genetics | Clusterin - biosynthesis | Prostate - metabolism | Estrogen Receptor beta - metabolism | Prostate - pathology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Keratins - biosynthesis | Estrogen Receptor beta - genetics | Aging - genetics | Receptors, Androgen - biosynthesis | Smad7 Protein - genetics | Chemokine CXCL16 - genetics | Chemokines, CXC - biosynthesis | Interleukin-6 - metabolism | PTEN Phosphohydrolase - genetics | Clusterin - genetics | Nedd4 Ubiquitin Protein Ligases - biosynthesis | Interleukin-6 - genetics | Signal Transduction | Chemokine CXCL16 - biosynthesis | Down-Regulation | PTEN Phosphohydrolase - biosynthesis | Chemokines, CXC - genetics | Aging - pathology | Mice, Knockout | Animals | Receptors, Androgen - genetics | Mice | Androgens - metabolism | Keratins - genetics | Smad7 Protein - biosynthesis | Proto-Oncogene Proteins c-bcl-2 - genetics | Aging - metabolism | Biological Sciences | PNAS Plus
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12. Full Text Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease
by Yu-bing Dai and Xin-jie Tan and Wan-fu Wu and Margaret Warner and Jan-Åke Gustafsson
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2012, Volume 109, Issue 32, pp. 13112 - 13117
Parkinson disease (PD) is a progressive neurodegenerative disease whose progression may be slowed, but at present there is no pharmacological intervention that... 
Dopaminergic neurons | Receptors | Neurons | Astrocytes | Substantia nigra | Neuroglia | Liver | Parkinson disease | Mice | Microglia | Neurodegeneration | Midbrain | Neuroinflammation | NERVOUS-SYSTEM | midbrain | TYROSINE-HYDROXYLASE | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | neurodegeneration | ALPHA-SYNUCLEIN | SUBSTANTIA-NIGRA | LXR-ALPHA | IN-VITRO | neuroinflammation | INFLAMMATION | LIPID HOMEOSTASIS | EXPRESSION | Immunohistochemistry | Microglia - metabolism | Male | Orphan Nuclear Receptors - metabolism | Orphan Nuclear Receptors - genetics | Substantia Nigra - cytology | Mice, Knockout | Glial Fibrillary Acidic Protein | Nerve Tissue Proteins - metabolism | Parkinsonian Disorders - metabolism | Orphan Nuclear Receptors - antagonists & inhibitors | Animals | Analysis of Variance | Parkinsonian Disorders - therapy | Dopaminergic Neurons - metabolism | Liver X Receptors | Benzoates - pharmacology | Parkinsonian Disorders - prevention & control | Benzylamines - pharmacology | Astrocytes - metabolism | Biological Sciences
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13. Full Text Echocardiographic Evaluation of Patients with Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA): A Single Medical Center Experience
by Hsu, Wan-Fu and Lee, Pi-Chang and Li, Hsing-Yuan and Huang, Shao-Wei and Wu, Fei-Yi and Weng, Zen-Chung and Hwang, Be-Tau
Ultrasound in Medicine & Biology, ISSN 0301-5629, 2017, Volume 43, pp. S67 - S67
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14. Full Text Estrogen receptor [beta], a regulator of androgen receptor signaling in the mouse ventral prostate
by Wu, Wan-fu and Maneix, Laure and Insunza, Jose and Nalvarte, Ivan and Antonson, Per and Kere, Juha and Yu, Nancy Yiu-Lin and Tohonen, Virpi and Katayama, Shintaro and Einarsdottir, Elisabet and Krjutskov, Kaarel and Dai, Yu-bing and Huang, Bo and Su, Wen and Warner, Margaret and Gustafsson, Jan-Ake
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, p. E3816
Immunohistochemistry | Usage | Receptors | Estrogen | Research | Gene expression | Prostate
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15. Estrogen receptor [Beta], a regulator of androgen receptor signaling in the mouse ventral prostate
by Wan-fu Wu and Laure Maneix and Jose Insunza and Ivan Nalvarte and Per Antonson and Juha Kere and Nancy Yiu-Lin Yu and Virpi Tohonen and Shintaro Katayama and Elisabet Einarsdottir and Kaarel Krjutskov and Yu-bing Dai and Bo Huang and Wen Su and Margaret Warner and Jan-Åke Gustafsson
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, p. E3816
As estrogen receptor β-/- (ERβ-/-) mice age, the ventral prostate (VP) develops increased numbers of hyperplastic, fibroplastic lesions and inflammatory cells.... 
Immunohistochemistry | Caveolin-1 | Estrogens | Hyperplasia | Estrogen | Clusterin | Interleukin 6 | Rodents | CXCL16 protein | Aging | Peroxidase | Prostatitis | Lesions | Ubiquitin-protein ligase | Glutathione peroxidase | Caveolin | Benign | Proteinase inhibitors | Inflammation | Ribonucleic acid--RNA | Gene expression | Cadherin | Nitric-oxide synthase | Androgens | Nitric oxide | Stem cells | Fibrosis | Tumor suppressor genes | Mice | Prostate cancer | Prostate
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16. Full Text Retinal and optic nerve degeneration in liver X receptor beta knockout mice
by Song, XY and Wu, WF and Gabbi, C and Dai, YB and So, M and Chaurasiya, SP and Wang, L and Warner, M and Gustafsson, JA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2019, Volume 116, Issue 33, pp. 16507 - 16512
The retina is an extension of the brain. Like the brain, neurodegeneration of the retina occurs with age and is the cause of several retinal diseases including... 
retinal degeneration | ACTIVATION | PROTEIN | CHOLESTEROL | INFLAMMATORY RESPONSES | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | NEURODEGENERATION | optic neuritis | beta amyloid | AMYLOID-BETA | aquaporin 4 | MOUSE MODEL | GLUTAMINE-SYNTHETASE | nuclear receptor | AQUAPORIN-4 | Glaucoma | Aquaporin 4 | Brain | Liver | Optic neuritis | Antibodies | Retina | Activation | Cerebrospinal fluid | Autophagy | Macular degeneration | Receptors | Cell activation | Neurodegeneration | Neuritis | Ganglion cells | Alzheimer's disease | Dopamine receptors | Optic nerve | Autoantibodies | Dopamine | Liver X receptors | Astrocytes | Microglia | Retinal ganglion cells | β-Amyloid | Mice | Phagocytosis | Apoptosis
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17. Full Text Targeting estrogen receptor [beta] in microglia and T cells to treat experimental autoimmune encephalomyelitis
by Wu, Wan-fu and Tan, Xin-jie and Dai, Yu-bing and Krishnan, Venkatesh and Warner, Margaret and Gustafsson, Jan-Ake
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 02/2013, Volume 110, Issue 9, p. 3543
A therapeutic goal in the treatment of certain CNS diseases, including multiple sclerosis, amyotrophic lateral sclerosis, and Parkinson disease, is to... 
Care and treatment | Receptors | Encephalomyelitis | Estrogen | Physiological aspects | T cells
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18. Targeting estrogen receptor [Beta] in microglia and T cells to treat experimental autoimmune encephalomyelitis
by Wan-fu Wu and Xin-jie Tan and Yu-bing Dai and Venkatesh Krishnan and Margaret Warner and Jan-Åke Gustafsson
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2013, Volume 110, Issue 9, p. 3543
  A therapeutic goal in the treatment of certain CNS diseases, including multiple sclerosis, amyotrophic lateral sclerosis, and Parkinson disease, is to... 
Molecules | Lymphocytes | Nitric oxide | Estrogen | Autoimmune diseases | Neurological disorders
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19. Seasonal variation of airborne bacteria of the Tiantishan Grottoes and Western Xia Museum, Wuwei
by Yu-Long Duan and Fa-Si Wu and Wan-Fu Wang and Dong-Peng He and Xiu-Shan Lu
Weishengwuxue Tongbao = Microbiology, ISSN 0253-2654, 01/2019, Issue 3, p. 468
[Background] Microbial deterioration is a common biological disease in ancient wall paintings,which seriously threaten the long-term safety preservation and... 
Communities | Phylogeny | Seasonal distribution | Gene sequencing | Seasonal variations | Airborne microorganisms | Microorganisms | Winter | Bacteria | Deoxyribonucleic acid--DNA | Community composition | Community structure | Biodeterioration | Preservation | rRNA | Rainfall | Museums | Bioaerosols | Spatial distribution | Historical structures | Airborne bacteria | Sampling methods | Environmental monitoring | Food processing industry | Arthrobacter | DNA sequencing
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20. Liver X receptor [Beta] protects dopaminergic neurons in a mouse model of Parkinson disease
by Yu-bing Dai and Xin-jie Tan and Wan-fu Wu and Margaret Warner and Jan-Åke Gustafsson
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2012, Volume 109, Issue 32, p. 13112
Parkinson disease (PD) is a progressive neurodegenerative disease whose progression may be slowed, but at present there is no pharmacological intervention that... 
Neurons | Liver | Medical treatment | Parkinsons disease | Cytotoxicity | Nervous system
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