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Cell, ISSN 0092-8674, 11/2008, Volume 135, Issue 4, pp. 702 - 713
Many immune system receptors signal through cytoplasmic tyrosine-based motifs (ITAMs), but how receptor ligation results in ITAM phosphorylation remains... 
MOLIMMUNO | SIGNALING | BILAYER | ZAP-70 | ZETA | COMPLEX | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFECTOR DOMAIN | BICELLES | CELL BIOLOGY
Journal Article
Nature Genetics, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 560 - 567
Journal Article
Journal of immunological methods, ISSN 0022-1759, 04/2019, Volume 469, pp. 47 - 51
Natural killer (NK) cell-mediated cytotoxicity is traditionally measured using the chromium release assay, which measures the fraction of radioactive Cr... 
Viral antibodies | Chromium | Antibodies | Killer cells | Analysis | Melanoma
Journal Article
Nature genetics, ISSN 1061-4036, 06/2019, Volume 51, Issue 6, pp. 1068 - 1068
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 10/2018, Volume 215, Issue 10, pp. 2617 - 2635
A number of autoimmunity-associated MHC class II proteins interact only weakly with the invariant chain-derived class II-associated invariant chain peptide... 
BETA-CHAIN | INSULIN | MEDICINE, RESEARCH & EXPERIMENTAL | DEPENDENT DIABETES-MELLITUS | HLA-DM | NOD MICE | CD4 T-CELLS | I-A(G7) | COMPLEXES | INVARIANT CHAIN PEPTIDE | IMMUNOLOGY | CELIAC-DISEASE | 300
Journal Article
Science, ISSN 0036-8075, 02/2018, Volume 359, Issue 6377, p. 770
Many human cancers are resistant to immunotherapy, for reasons that are poorly understood. We used a genome-scale CRISPR-Cas9 screen to identify mechanisms of... 
Tumor suppressor genes | Chromatin | T cells | Analysis | Cancer cells
Journal Article
Nature communications, 11/2017, Volume 8, Issue 1, p. 1747
Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because... 
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2001, Volume 2, Issue 6, pp. 501 - 507
The class II major histocompatibility complex (MHC) glycoproteins HLA-DQ8 and HLA-DQ2 in humans and I-A(g7) in nonobese diabetic (NOD) mice are the major risk... 
MYELIN BASIC-PROTEIN | NOD MOUSE | GLUTAMIC-ACID DECARBOXYLASE | PEPTIDE-BINDING | CRYSTAL-STRUCTURE | HLA-DQ | MAJOR HISTOCOMPATIBILITY COMPLEX | T-CELL EPITOPE | IMMUNOLOGY | SELF-PEPTIDES | CELIAC-DISEASE
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 01/2018, Volume 115, Issue 4, p. E686
The B-lymphotropic Epstein-Barr virus (EBV), pandemic in humans, is rapidly controlled on initial infection by T cell surveillance; thereafter, the virus... 
Physiological aspects | Microbiological research | Cellular signal transduction | Epstein-Barr virus | Research | T cells
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2010, Volume 185, Issue 11, pp. 6391 - 6393
Journal Article
Oncoimmunology, ISSN 2162-4011, 2014, Volume 3, p. e28500
A key challenge facing the cancer immunology field is the discovery of the most suitable targets for therapeutic intervention. We recently reported a novel... 
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7490, pp. 118 - 123
The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend on intercellular contacts between T cells and... 
SUPRAMOLECULAR ACTIVATION CLUSTER | ADHESION | COMPLEX | PROTEIN | MULTIDISCIPLINARY SCIENCES | DYNAMICS | PROLIFERATION | MICROSCOPY | CLASS-II | ELECTRON TOMOGRAPHY | MOLECULES | Cell Polarity | Virus Release | Antigen-Presenting Cells - cytology | Vesicular Transport Proteins - metabolism | Humans | Secretory Vesicles - metabolism | Male | Receptors, Antigen, T-Cell - ultrastructure | Immunological Synapses - metabolism | CD4-Positive T-Lymphocytes - immunology | DNA-Binding Proteins - metabolism | Histocompatibility Antigens Class I - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | Female | HIV - metabolism | Receptors, Antigen, T-Cell - immunology | CD4-Positive T-Lymphocytes - virology | B-Lymphocytes - metabolism | Antigen-Presenting Cells - metabolism | B-Lymphocytes - cytology | Immunological Synapses - ultrastructure | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Lymphocyte Activation | CD4-Positive T-Lymphocytes - metabolism | Endosomal Sorting Complexes Required for Transport - metabolism | Histocompatibility Antigens Class I - immunology | Immunological Synapses - secretion | Antigen-Presenting Cells - immunology | Protein Transport | Transcription Factors - metabolism | Secretory Vesicles - secretion | Intercellular Adhesion Molecule-1 - metabolism | Animals | B-Lymphocytes - immunology | CD4-Positive T-Lymphocytes - secretion | Protein Binding | Mice | Medicine | Plasma | Medical imaging | Microscopy | Lymphocytes | Rheumatology | Tomography | T cell receptors | Biology | Cytoplasm
Journal Article
Nature, ISSN 0028-0836, 3/2014, Volume 507, Issue 7490, pp. 118 - 123
The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend on intercellular contacts between T cells and antigen... 
Journal Article
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