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PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164795
Introduction Human induced pluripotent stem cells (hiPSCs) offer a unique opportunity for disease modeling. However, it is not invariably successful to... 
RATE DEPENDENCE | CALCIUM-RELEASE CHANNELS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | SUDDEN CARDIAC DEATH | MUSCLE | CHANNEL RYANODINE RECEPTOR | CARDIOMYOCYTES | MUTATIONS | FAILING HEARTS | FKBP12.6 | Electric Stimulation | Anti-Asthmatic Agents - therapeutic use | Calcium - metabolism | Humans | Ryanodine Receptor Calcium Release Channel - metabolism | Transplantation, Heterologous | Calsequestrin - genetics | Thiazepines - therapeutic use | Calreticulin - genetics | Thiazepines - chemistry | Calreticulin - metabolism | Adult | Induced Pluripotent Stem Cells - cytology | Calsequestrin - metabolism | Action Potentials - drug effects | Ryanodine - pharmacology | Anti-Asthmatic Agents - chemistry | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Tachycardia, Ventricular - therapy | Anti-Asthmatic Agents - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Myocytes, Cardiac - cytology | Tachycardia, Ventricular - drug therapy | Cells, Cultured | Thiazepines - pharmacology | Mice, SCID | Myocytes, Cardiac - transplantation | Animals | Myocytes, Cardiac - drug effects | Ryanodine Receptor Calcium Release Channel - genetics | Cell Differentiation - drug effects | Models, Biological | Isoproterenol - pharmacology | Ryanodine Receptor Calcium Release Channel - chemistry | Tachycardia, Ventricular - pathology | Mice, Inbred NOD | Fibroblasts - cytology | Mice | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Medical research | Stem cells | Medicine, Experimental | Ventricular tachycardia | Models | Medical screening | Electric fields | Health aspects | Cardiac arrhythmia | Biotechnology | Phosphorylation | Transcription factors | Science | Action potential | Isoproterenol | Rodents | Fibroblasts | Physiology | Cardiology | Deoxyribonucleic acid--DNA | University graduates | Phenotypes | Incubation | Calcium imaging | Cardiomyocytes | Pharmacology | Gene expression | Chemical compounds | Patients | Medicine | Tachycardia | Mutation | Ventricle | Pluripotency | Calcium ions | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 12/2017, Volume 10, Issue 6, pp. e001603 - e001603
Journal Article
Stem Cell Reports, ISSN 2213-6711, 08/2019, Volume 13, Issue 2, pp. 394 - 404
For long QT syndrome (LQTS), recent progress in genome-sequencing technologies enabled the identification of rare genomic variants with diagnostic, prognostic,... 
genome editing | phenotype-based diagnosis | long QT syndrome | induced pluripotent stem cell | multi-electrode array | ACTION-POTENTIALS | MANAGEMENT | GENETICS | ERA | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A14298 - A14298
BackgroundCalmodulin is a ubiquitous Ca-sensor molecule and an identical calmodulin protein is encoded by the 3 distinct genes, CALM1-3. Recently, mutations in... 
Journal Article
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A17739 - A17739
BackgroundCalmodulin (CALM) is a ubiquitous Ca2+-sensor molecule, and it modulates various proteins including several ion channels, ryanodine receptor 2, and... 
Journal Article
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