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PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, p. e37243
It has been proposed that the anti-inflammatory effects of intravenous immunoglobulin (IVIG) might be due to the small fraction of Fc-sialylated IgG. In this... 
ANTIINFLAMMATORY ACTIVITY | AUTOIMMUNE | DISEASES | THERAPY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | THROMBOCYTOPENIC PURPURA | GAMMA-GLOBULIN | IMMUNODEFICIENCIES | IGG FC | Anti-Inflammatory Agents - pharmacology | Immunoglobulin Fc Fragments - metabolism | Electrophoresis, Polyacrylamide Gel | Humans | Chromatography, High Pressure Liquid | Immunoglobulins, Intravenous - pharmacology | N-Acetylneuraminic Acid - metabolism | Blotting, Western | Erythrocytes - drug effects | Ribosome Inactivating Proteins - metabolism | Immunoglobulins, Intravenous - metabolism | Chromatography, Affinity | Antibody Specificity - immunology | Immunoglobulin Fab Fragments - metabolism | Chemical Fractionation | Mass Spectrometry | Protein Binding - drug effects | Erythrocytes - metabolism | Plant Lectins - metabolism | Lactose | Analysis | Immunoglobulin G | Inflammation | B cells | Immunity | Enzyme-linked immunosorbent assay | Organic acids | Intravenous administration | Guillain-Barre syndrome | Antibodies | Acidification | Arthritis | Inflammatory diseases | Lipopolysaccharides | Trends | Immune system | Antigens | Encephalitis | Elution | Fractionation | Immunoglobulins | Antiinflammatory agents | Research & development--R&D | Secretion | Fab | Rheumatic diseases | Autoantigens | Liquid chromatography | High-performance liquid chromatography | Allergies | Chromatography | Monocytes | Acids | Lectins | Scientific imaging | Mass spectrometry | Monocyte chemoattractant protein 1 | Research & development | R&D
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2019, Volume 144, Issue 2, pp. 524 - 535.e8
Journal Article
Journal Article
Transfusion, ISSN 0041-1132, 07/2015, Volume 55, Issue S2, pp. S95 - S97
BACKGROUND Hemolysis reaction is a rare class effect of therapy with intravenously administered human normal immunoglobulin (IVIG). Anti‐A/B isoagglutinins... 
HEMATOLOGY | GLOBULIN | Blood Donors | Hemagglutinins - blood | ABO Blood-Group System - chemistry | Hemagglutinins - chemistry | Humans | Plasma - chemistry | Donor Selection - methods | Female | Male | Immunoglobulins, Intravenous - chemistry | ABO Blood-Group System - blood | Immunoglobulins | Plasma
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 2, pp. AB81 - AB81
  Rationale Titers of anti-A and anti-B antibodies (isoagglutinins) in intravenous immunoglobulin (IVIG) products correlate with the risk of hemolysis. [...]it... 
Allergy and Immunology | Immunoglobulins | Chromatography
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 03/2017, Volume 8, p. 275
Circulating immunoglobulins including immunoglobulin G (IgG) and IgM play a critical role in the immune homeostasis by modulating functions of immune cells.... 
Natural antibodies | FcaRI | DC-SIGN | IL-17 | Treg | Monomeric IgA | IVIG | CD89 | Th17 | DENDRITIC CELLS | SECRETORY IGA | monomeric IgA | Fc alpha RI | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | HUMAN MONOCYTES | NATURAL IGM | natural antibodies | RECIPROCAL REGULATION | INTRAVENOUS IMMUNOGLOBULIN | AUTOIMMUNE-DISEASES | REGULATORY T-CELLS | INFLAMMATORY-DISEASES | Life Sciences | Immunology
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 2, pp. AB97 - AB97
  Specific IAC reduced anti-A and anti-B titers by at least two 2-fold dilution steps in the final product (>80% reduction shown by flow cytometry on standard... 
Allergy and Immunology | Chromatography | Plasma | Flow cytometry
Journal Article
Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2019, Volume 144, Issue 2, pp. 524 - 535.e8
BACKGROUND: Therapeutic normal IgG or intravenous immunoglobulin (IVIG) exerts anti-inflammatory effects through several mutually nonexclusive mechanisms.... 
Life Sciences | Immunology | Immunotherapy
Journal Article
Transfusion, ISSN 0041-1132, 07/2015, Volume 55, Issue S2, pp. S95 - S97
Journal Article
Biologics in Therapy, ISSN 2195-5840, 12/2014, Volume 4, Issue 1, pp. 15 - 26
Hemolysis is considered a class effect and a rare adverse event that can occur following therapy with human normal immunoglobulin for intravenous... 
Hemolysis | Anti-A/B isoagglutinin | Hematology | Rheumatology | Internal Medicine | Oncology | Plasma donor screening | Intravenous immunoglobulin (IVIG) | Medicine & Public Health | Gastroenterology | Privigen | Infectious Diseases | Isoagglutinin | Endocrinology | Hemolytic risk | Isohemagglutinins
Journal Article
The Journal of allergy and clinical immunology, 12/2018
Therapeutic normal IgG or intravenous immunoglobulin (IVIG) exerts anti-inflammatory effects through several mutually nonexclusive mechanisms. Recent data in... 
Journal Article