Renal Failure, ISSN 0886-022X, 01/2019, Volume 41, Issue 1, pp. 821 - 831
Background: Obesity has become a worldwide epidemic, and the incidence of obesity is increasing year by year. Obesity-related nephropathy (ORN) is a common...
Oxidative stress | Nrf2 | ACSL1 | obesity-related nephropathy | lipid deposition
Oxidative stress | Nrf2 | ACSL1 | obesity-related nephropathy | lipid deposition
Journal Article
Nanoscale Research Letters, ISSN 1931-7573, 12/2019, Volume 14, Issue 1, pp. 1 - 9
RNA interference (RNAi) has potential advantages over other gene therapy approaches due to its high specificity and the ability to inhibit target gene...
Materials Science | RNA interference | Nanotechnology and Microengineering | siRNA delivery | Molecular Medicine | Anti-nucleolin aptamer AS1411 | Nanochemistry | Gene therapy | Nanoscale Science and Technology | Nucleolin targeting | Nanotechnology | RNAI | PHYSICS, APPLIED | AS1411 | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | STRATEGIES | NANOPARTICLES | THERAPY | GENE | Biological products | RNA | Genes | Therapeutics | Gene expression | Homeopathy | Materia medica and therapeutics
Materials Science | RNA interference | Nanotechnology and Microengineering | siRNA delivery | Molecular Medicine | Anti-nucleolin aptamer AS1411 | Nanochemistry | Gene therapy | Nanoscale Science and Technology | Nucleolin targeting | Nanotechnology | RNAI | PHYSICS, APPLIED | AS1411 | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | STRATEGIES | NANOPARTICLES | THERAPY | GENE | Biological products | RNA | Genes | Therapeutics | Gene expression | Homeopathy | Materia medica and therapeutics
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2015, Volume 5, Issue 1, p. 16317
Concerted efforts in genomic studies examining RNA transcription and DNA methylation patterns have revealed profound insights in prognostic ovarian cancer...
EVOLUTION | CANCER | CARCINOMA | MULTIDISCIPLINARY SCIENCES | Immunohistochemistry | Multivariate Analysis | Automation | Prognosis | Humans | Middle Aged | Ovarian Neoplasms - pathology | Proportional Hazards Models | Tumor Microenvironment | Survival Rate | Ovarian Neoplasms - mortality | Disease Progression | Disease-Free Survival | Aged, 80 and over | Adult | Female | Aged | Neoplasm Staging | Stromal Cells - cytology | Cell survival | Image processing | Therapeutic applications | Histology | Multivariate analysis | Ribonucleic acid--RNA | Survival | Ovarian cancer | Stromal cells | DNA methylation | Tumors
EVOLUTION | CANCER | CARCINOMA | MULTIDISCIPLINARY SCIENCES | Immunohistochemistry | Multivariate Analysis | Automation | Prognosis | Humans | Middle Aged | Ovarian Neoplasms - pathology | Proportional Hazards Models | Tumor Microenvironment | Survival Rate | Ovarian Neoplasms - mortality | Disease Progression | Disease-Free Survival | Aged, 80 and over | Adult | Female | Aged | Neoplasm Staging | Stromal Cells - cytology | Cell survival | Image processing | Therapeutic applications | Histology | Multivariate analysis | Ribonucleic acid--RNA | Survival | Ovarian cancer | Stromal cells | DNA methylation | Tumors
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 07/2018, Volume 114, pp. 143 - 148
Papain enzyme was successfully immobilized by covalent bonding onto biocompatible Fe O /SF nanoparticles, which were prepared with the soft template of silk...
Immobilization | Papain | Magnetism | Porous Fe3O4 | Covalent cross-linking | Porous Fe | O | PENICILLIN-G ACYLASE | POLYMER SCIENCE | BIOMINERALIZATION | MICROSPHERES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBACTERIAL | AMYLASE | LIPASE | CHEMISTRY, APPLIED | Nanoparticles | Hydrolysis | Magnetic fields
Immobilization | Papain | Magnetism | Porous Fe3O4 | Covalent cross-linking | Porous Fe | O | PENICILLIN-G ACYLASE | POLYMER SCIENCE | BIOMINERALIZATION | MICROSPHERES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIBACTERIAL | AMYLASE | LIPASE | CHEMISTRY, APPLIED | Nanoparticles | Hydrolysis | Magnetic fields
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 02/2017, Volume 70, Issue 2, p. 145
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 02/2017, Volume 70, Issue 2, p. 145
Aims A novel heterozygous variant, FGA c.169_180+2 del (designated fibrinogen Shanghai), was identified in a patient with dysfibrinogenemia with...
Journal Article
Analytica Chimica Acta, ISSN 0003-2670, 07/2013, Volume 789, pp. 100 - 106
In this paper, four organic acids constituents of Plateau alfalfa roots have been identified and detected by a novel capillary electrophoresis (CE) strategy...
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2010, Volume 285, Issue 45, pp. 34621 - 34631
The formation of a β-catenin·TCF4 complex in the nucleus of cells is well known as a prerequisite for the transcription of Wnt target genes. Although many...
T-cell Factor (TCF) | Signal Transduction | p15RS | β-Catenin | Tumor | Wnt Pathway | Cell Biology
T-cell Factor (TCF) | Signal Transduction | p15RS | β-Catenin | Tumor | Wnt Pathway | Cell Biology
Journal Article
Journal of Clinical Pathology, ISSN 0021-9746, 02/2017, Volume 70, Issue 2, pp. 145 - 153
AimsA novel heterozygous variant, FGA c.169_180+2 del (designated fibrinogen Shanghai), was identified in a patient with dysfibrinogenemia with...
CLOT FORMATION | PLASMA-FIBRINOGEN | CONGENITAL DYSFIBRINOGENEMIA | THROMBIN | PATHOLOGY | CHINESE PATIENTS | MOLECULAR-BASIS | DOMAINS | MANIFESTATIONS | FEATURES | Afibrinogenemia - metabolism | Humans | Venous Thrombosis - metabolism | Afibrinogenemia - complications | Male | Antiphospholipid Syndrome - complications | Fibrinogen - genetics | Young Adult | China | Fibrinogen - metabolism | Antiphospholipid Syndrome - genetics | Venous Thrombosis - genetics | Afibrinogenemia - genetics | Mutation | Fibrin - metabolism | Antiphospholipid Syndrome - metabolism
CLOT FORMATION | PLASMA-FIBRINOGEN | CONGENITAL DYSFIBRINOGENEMIA | THROMBIN | PATHOLOGY | CHINESE PATIENTS | MOLECULAR-BASIS | DOMAINS | MANIFESTATIONS | FEATURES | Afibrinogenemia - metabolism | Humans | Venous Thrombosis - metabolism | Afibrinogenemia - complications | Male | Antiphospholipid Syndrome - complications | Fibrinogen - genetics | Young Adult | China | Fibrinogen - metabolism | Antiphospholipid Syndrome - genetics | Venous Thrombosis - genetics | Afibrinogenemia - genetics | Mutation | Fibrin - metabolism | Antiphospholipid Syndrome - metabolism
Journal Article
Organometallics, ISSN 0276-7333, 04/2014, Volume 33, Issue 8, pp. 1972 - 1976
The formation of mixed-valent ytterbium and europium complexes L4LnIII 2LnII (Ln = Yb (1), Eu (2)) was observed for the first time in the spontaneous reduction...
AMINE BIS(PHENOLATE) LIGANDS | ORGANOLANTHANIDE COMPLEXES | HOMOLYSIS | CRYSTAL-STRUCTURE | FUNCTIONALIZED INDENYL LIGANDS | REACTIVITY | CHEMISTRY, ORGANIC | N BOND | CATALYTIC-ACTIVITY | LANTHANIDE CHEMISTRY | EU BOND | CHEMISTRY, INORGANIC & NUCLEAR
AMINE BIS(PHENOLATE) LIGANDS | ORGANOLANTHANIDE COMPLEXES | HOMOLYSIS | CRYSTAL-STRUCTURE | FUNCTIONALIZED INDENYL LIGANDS | REACTIVITY | CHEMISTRY, ORGANIC | N BOND | CATALYTIC-ACTIVITY | LANTHANIDE CHEMISTRY | EU BOND | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Cancer Cell, ISSN 1535-6108, 01/2012, Volume 21, Issue 1, pp. 92 - 104
Tumorigenesis is caused by an uncontrolled cell cycle and the altered expression of many genes. Here, we report a gene that is preferentially expressed in...
RNA-POLYMERASE-II | BREAST-CANCER | ONCOGENES | CDK INHIBITORS | ONCOLOGY | PART | TUMOR | TARGETS | MAMMALIAN-CELLS | CANCER-THERAPY | DEPENDENT KINASES | CELL BIOLOGY | Genes, bcl-1 - genetics | Neoplasms - metabolism | Cell Cycle - genetics | Cell Proliferation | Humans | Neoplasm Proteins - physiology | Cell Cycle Proteins - metabolism | Embryonic Development - genetics | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | RNA Polymerase II - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Cell Transformation, Neoplastic - metabolism | Protein Interaction Mapping | Animals | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Cell Cycle Proteins - genetics | Cell Line, Tumor | Transcription, Genetic | Mice | Neoplasm Proteins - genetics | Cell Cycle Proteins - physiology | Chromatin | Genetic aspects | RNA | Children's hospitals | Genes | Tumors
RNA-POLYMERASE-II | BREAST-CANCER | ONCOGENES | CDK INHIBITORS | ONCOLOGY | PART | TUMOR | TARGETS | MAMMALIAN-CELLS | CANCER-THERAPY | DEPENDENT KINASES | CELL BIOLOGY | Genes, bcl-1 - genetics | Neoplasms - metabolism | Cell Cycle - genetics | Cell Proliferation | Humans | Neoplasm Proteins - physiology | Cell Cycle Proteins - metabolism | Embryonic Development - genetics | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | RNA Polymerase II - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Cell Transformation, Neoplastic - metabolism | Protein Interaction Mapping | Animals | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Cell Cycle Proteins - genetics | Cell Line, Tumor | Transcription, Genetic | Mice | Neoplasm Proteins - genetics | Cell Cycle Proteins - physiology | Chromatin | Genetic aspects | RNA | Children's hospitals | Genes | Tumors
Journal Article
Analytica Chimica Acta, ISSN 0003-2670, 07/2013, Volume 789, pp. 100 - 106
In this paper, four organic acids constituents of Plateau alfalfa roots have been identified and detected by a novel capillary electrophoresis (CE) strategy...
On-line concentration | Capillary electrophoresis | Plateau alfalfa roots | Organic acids | LIQUID-PHASE MICROEXTRACTION | SYSTEM | PRECONCENTRATION | CHEMISTRY, ANALYTICAL | MALATE-DEHYDROGENASE | CHROMATOGRAPHY | ASCORBIC-ACID | MASS-SPECTROMETRY | GALLIC ACID | MICROCHIP ELECTROPHORESIS | EXUDATION | Surface-Active Agents | Limit of Detection | Reproducibility of Results | Chitosan - chemistry | Plant Roots - chemistry | Medicago sativa - chemistry | Electrophoresis, Capillary - methods | Online Systems | Organic Chemicals - analysis | Citric Acid - analysis | Carboxylic Acids - analysis | Enrichment | Trapping | Linearity | Roots | Electrophoresis | Alfalfa | Chitosan
On-line concentration | Capillary electrophoresis | Plateau alfalfa roots | Organic acids | LIQUID-PHASE MICROEXTRACTION | SYSTEM | PRECONCENTRATION | CHEMISTRY, ANALYTICAL | MALATE-DEHYDROGENASE | CHROMATOGRAPHY | ASCORBIC-ACID | MASS-SPECTROMETRY | GALLIC ACID | MICROCHIP ELECTROPHORESIS | EXUDATION | Surface-Active Agents | Limit of Detection | Reproducibility of Results | Chitosan - chemistry | Plant Roots - chemistry | Medicago sativa - chemistry | Electrophoresis, Capillary - methods | Online Systems | Organic Chemicals - analysis | Citric Acid - analysis | Carboxylic Acids - analysis | Enrichment | Trapping | Linearity | Roots | Electrophoresis | Alfalfa | Chitosan
Journal Article
Hanjie Xuebao/Transactions of the China Welding Institution, ISSN 0253-360X, 03/2015, Volume 36, Issue 3, pp. 97 - 100
Journal Article
Plasma Science and Technology, ISSN 1009-0630, 07/2012, Volume 14, Issue 7, pp. 665 - 669
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2012, Volume 421, Issue 4, pp. 651 - 657
► Rab21 interacts and co-localizes with EGFR. ► Rab21 promotes EGFR degradation by enhancing its internalization. ► Rab21 attenuates EGF-stimulated MAPK...
Degradation | Rab21 | Internalization | EGFR | MAPK signaling | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCYTIC TRAFFICKING | FACTOR RECEPTOR | BIOPHYSICS | GTPASES | EPIDERMAL-GROWTH-FACTOR | EXPRESSION | BINDING | rab GTP-Binding Proteins - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Proteolysis | Humans | HEK293 Cells | Epidermal Growth Factor - metabolism | rab GTP-Binding Proteins - genetics | Epidermal Growth Factor - pharmacology | HeLa Cells
Degradation | Rab21 | Internalization | EGFR | MAPK signaling | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCYTIC TRAFFICKING | FACTOR RECEPTOR | BIOPHYSICS | GTPASES | EPIDERMAL-GROWTH-FACTOR | EXPRESSION | BINDING | rab GTP-Binding Proteins - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Proteolysis | Humans | HEK293 Cells | Epidermal Growth Factor - metabolism | rab GTP-Binding Proteins - genetics | Epidermal Growth Factor - pharmacology | HeLa Cells
Journal Article
Plasma Science and Technology, ISSN 1009-0630, 05/2012, Volume 14, Issue 5, pp. 415 - 418
Journal Article
Plasma Science and Technology, ISSN 1009-0630, 05/2012, Volume 14, Issue 5, pp. 415 - 418
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2011, Volume 27, Issue 5, pp. 503 - 512
Wnt signaling is critical for many biological processes and is tightly regulated. In this study, we found that GABARAPL1 (GABAA receptor-associated protein...
Original Paper | Dvl2 | GABARAPL1 | Wnt signaling | Autophagy | PHYSIOLOGY | PROTEIN | POLARITY | UBIQUITIN | MECHANISMS | INHIBITOR | EXPRESSION | Neoplasm Transplantation | Up-Regulation | Wnt1 Protein - antagonists & inhibitors | Wnt1 Protein - genetics | Cell Proliferation | Immunoprecipitation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Uterine Cervical Neoplasms - pathology | Wnt1 Protein - metabolism | Phosphoproteins - metabolism | Breast Neoplasms - metabolism | Transfection | Uterine Cervical Neoplasms - metabolism | Cloning, Molecular | HEK293 Cells | Female | Dishevelled Proteins | Gene Expression | Signal Transduction | Luciferases - analysis | Phosphoproteins - genetics | beta Catenin - metabolism | beta Catenin - genetics | Two-Hybrid System Techniques | Animals | Breast Neoplasms - pathology | Mice, Nude | Plasmids | beta Catenin - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | Mice | Adaptor Proteins, Signal Transducing - metabolism
Original Paper | Dvl2 | GABARAPL1 | Wnt signaling | Autophagy | PHYSIOLOGY | PROTEIN | POLARITY | UBIQUITIN | MECHANISMS | INHIBITOR | EXPRESSION | Neoplasm Transplantation | Up-Regulation | Wnt1 Protein - antagonists & inhibitors | Wnt1 Protein - genetics | Cell Proliferation | Immunoprecipitation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Uterine Cervical Neoplasms - pathology | Wnt1 Protein - metabolism | Phosphoproteins - metabolism | Breast Neoplasms - metabolism | Transfection | Uterine Cervical Neoplasms - metabolism | Cloning, Molecular | HEK293 Cells | Female | Dishevelled Proteins | Gene Expression | Signal Transduction | Luciferases - analysis | Phosphoproteins - genetics | beta Catenin - metabolism | beta Catenin - genetics | Two-Hybrid System Techniques | Animals | Breast Neoplasms - pathology | Mice, Nude | Plasmids | beta Catenin - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | Mice | Adaptor Proteins, Signal Transducing - metabolism
Journal Article
等离子体科学和技术:英文版, ISSN 1009-0630, 2012, Volume 14, Issue 7, pp. 665 - 669
The transport process of 12C ions in water was studied with SRIM code and Geant4 toolkit. The SRIM results indicate that the transverse diffusion of 12C ion...
SRIM | 扭曲 | 离子水 | 横向扩散 | 运输过程 | 能量沉积分布 | Geant4 | 正电子发射 | energy deposit distribution | C ions | secondary fragments | simulation
SRIM | 扭曲 | 离子水 | 横向扩散 | 运输过程 | 能量沉积分布 | Geant4 | 正电子发射 | energy deposit distribution | C ions | secondary fragments | simulation
Journal Article
07/2018
The invention discloses high-bulk wrapping paper with a cold storage function and a preparation method of the wrapping paper. The wrapping paper comprises a...
PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D | TRANSPORTING | PRODUCTION OF CELLULOSE | TEXTILES | PAPER-MAKING | LAYERED PRODUCTS | PAPER | LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM | TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G | PAPER NOT OTHERWISE PROVIDED FOR | PULP COMPOSITIONS | IMPREGNATING OR COATING OF PAPER | PERFORMING OPERATIONS
PREPARATION THEREOF NOT COVERED BY SUBCLASSES D21C OR D21D | TRANSPORTING | PRODUCTION OF CELLULOSE | TEXTILES | PAPER-MAKING | LAYERED PRODUCTS | PAPER | LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT ORNON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM | TREATMENT OF FINISHED PAPER NOT COVERED BY CLASS B31 OR SUBCLASS D21G | PAPER NOT OTHERWISE PROVIDED FOR | PULP COMPOSITIONS | IMPREGNATING OR COATING OF PAPER | PERFORMING OPERATIONS
Patent
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