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Journal of Hepatology, ISSN 0168-8278, 09/2017, Volume 67, Issue 3, p. 508
Background & Aims Currently, there are no recommendations in guidelines concerning the preferred diameter of stents for transjugular intrahepatic portosystemic... 
Liver diseases | Syngeneic grafts | Medical treatment | Hemorrhage | Survival | Allografts | Hepatology | Encephalopathy | Implants | Stents | Liver cirrhosis | Hepatic encephalopathy | Liver transplantation
Journal Article
Journal of Biopharmaceutical Statistics, ISSN 1054-3406, 11/2017, Volume 27, Issue 6, pp. 945 - 962
The primary objective of a multiregional clinical trial (MRCT) is to assess the efficacy of all participating regions and evaluate the probability of applying... 
MRCT | Discounting factor | sample size estimation | virtual trial | nested group sequential design | global drug development | DESIGN | SAMPLE-SIZE CONSIDERATIONS | STATISTICS & PROBABILITY | CONSISTENCY ASSESSMENT | MULTIREGIONAL CLINICAL-TRIALS | PHARMACOLOGY & PHARMACY | QUALITATIVE INTERACTIONS | JAPANESE PATIENTS
Journal Article
Communications in Statistics - Simulation and Computation, ISSN 0361-0918, 01/2014, Volume 43, Issue 2, pp. 254 - 268
Instead of using traditional separate phase I and II trials, in this article, we propose using a parallel three-stage phase I/II design, incorporating a dose... 
Bayesian adaptive design | Dose finding | Dose expansion | Primary 62L05 | Phase I/II | Secondary 62F15 | PLAY-WINNER RULE | DRUG | EFFICACY | STATISTICS & PROBABILITY | TOXICITY | I CLINICAL-TRIALS | Simulation | Programming languages | Randomization | Effectiveness | Computer simulation | Toxicity | Safety | Bayesian analysis | Patients | Monitoring
Journal Article
Circulation research, 04/2019, Volume 124, Issue 9, pp. 1386 - 1400
Exercise training, in addition to reducing cardiovascular risk factors, confers direct protection against myocardial ischemia/reperfusion injury and has been... 
cardioprotection | hypoxia | exercise | microRNA | myocardial ischemia | exosomes
Journal Article
Contemporary Clinical Trials, ISSN 1551-7144, 05/2018, Volume 68, pp. 67 - 71
Proton pump inhibitors (PPIs) are the main drugs for the treatment of reflux esophagitis. Phase II clinical trials showed that, compared with Esomeprazole, the... 
Treatment | Ilaparazole | Gastroesophageal reflux disease | Reflux esophagitis | Proton pump inhibitor | MEDICINE, RESEARCH & EXPERIMENTAL | ILAPRAZOLE | DUODENAL-ULCER | OMEPRAZOLE | PHARMACOKINETICS | DISEASE | PHARMACOLOGY & PHARMACY | EPIDEMIOLOGY | Gastroesophageal reflux | Medicine, Experimental | Clinical trials | Esophagitis | Medical research
Journal Article
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 01/2019, Volume 15, Issue 1, pp. 249 - 255
To evaluate the safety and immunogenicity of a newly 23-valent pneumococcal polysaccharide vaccine (PPV23), a phase Ⅲ clinical trial was conducted in... 
safety | immunogenicity | 23-valent pneumococcal polysaccharide vaccine | phase Ⅲ clinical trial | CONJUGATE VACCINE | ANTIBODY PERSISTENCE | REVACCINATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COVERAGE | DISEASE | PREVENTION | phase 2162; clinical trial | IMMUNOLOGY
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