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Journal Article
Tumor Biology, ISSN 1010-4283, 7/2017, Volume 39, Issue 7, pp. 1010428317712102 - 1010428317712102
In cholestasis, increases in bile acid levels result in the generation of reactive oxygen species and the induction of DNA damage and mutation. It is believed... 
GCDA | Poly(ADP-ribose) polymerase | Mcl-1 | Base excision repair | Bile acid | DNA damage | AP ENDONUCLEASE | bile acid | poly(ADP-ribose) polymerase | REGENERATION | base excision repair | PARP | BASE EXCISION-REPAIR | ONCOLOGY | LIVER | BCL2 | EXPRESSION | CARCINOMA | DNA Damage - drug effects | Cholestasis - genetics | Reactive Oxygen Species - metabolism | Cholestasis - metabolism | Liver Neoplasms - genetics | Bile Acids and Salts - toxicity | Humans | Hepatocytes - pathology | DNA Repair - genetics | Hepatocytes - metabolism | DNA-Binding Proteins - genetics | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Gene Knockdown Techniques | Hep G2 Cells | Cholestasis - pathology | Bile Acids and Salts - standards | Poly(ADP-ribose) Polymerases - genetics | Glycochenodeoxycholic Acid - toxicity | Liver Neoplasms - metabolism | Liver Neoplasms - pathology | Apurinic Acid - genetics | Gene Expression Regulation, Neoplastic - drug effects | X-ray Repair Cross Complementing Protein 1 | Hepatocytes - drug effects | Reactive oxygen species | Bcl-2 protein | Authorship | Laboratories | Genes | Liver | Poly(ADP-ribose) | Gallbladder diseases | Genomes | DNA repair | Carcinogenesis | Genomic instability | Proteins | Ribose | Tumorigenesis | Deoxyribonucleic acid--DNA | XRCC1 protein | Immunoglobulins | Bile acids | Cell survival | Research & development--R&D | RNA-mediated interference | Mcl-1 protein | Studies | Plasmids | Cholestasis | Cancer | Bile | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e24590 - e24590
Background: It has been documented all-trans retinoic acid (atRA) promotes the development of TGF-beta-induced CD4(+) Foxp3(+) regulatory T cells (iTreg) that... 
ACTIVATION | SMAD3 | BIOLOGY | REGULATORY T-CELLS | HOST-DISEASE | DIFFERENTIATION | INDUCTION | RECEPTORS | EXPRESSION | BINDING | TH17 CELLS | T-Lymphocytes, Regulatory - metabolism | Phosphorylation | Histones - chemistry | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Interleukin-2 Receptor alpha Subunit - biosynthesis | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Forkhead Transcription Factors - genetics | DNA - genetics | DNA Methylation | Animals | Tretinoin - metabolism | Forkhead Transcription Factors - metabolism | Female | Cell Differentiation | Mice | Transforming Growth Factor beta - metabolism | Graft-versus-host reaction | Anergy | Central nervous system | Recruitment | Proteins | Vitamin A | Demethylation | Signal transduction | Chinese medicine | Conserved sequence | Smad2 protein | CD25 antigen | Foxp3 protein | Acetylation | Deoxyribonucleic acid--DNA | Immunoregulation | Rheumatology | CD3 antigen | Gene expression | Fatty acids | Children & youth | Hospitals | Molecular modelling | Retinoic acid | Transplants & implants | Antibodies | Transplantation | Lymphocytes T | Genomes | Biology | Kinases | CD28 antigen | DNA-directed RNA polymerase | Infusion | Immunology | Lymphocytes | Rodents | DNA methylation | Trends | Nucleotide sequence | Extracellular signal-regulated kinase | Ribonucleic acid--RNA | Loci | CD4 antigen | Polymerase | Signaling | Acids | Diabetes | Methylation | Autoimmune diseases | Differentiation | RNA polymerase II | Apoptosis | Index Medicus | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2011, Volume 6, Issue 8, pp. e23629 - e23629
Background: BAFF, in addition to promoting B cell survival and differentiation, may affect T cells. The objective of this study was to determine the effect of... 
B-LYMPHOCYTE STIMULATOR | COLLAGEN-INDUCED ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | MULTIPLE-SCLEROSIS | IMMUNE-RESPONSES | NECROSIS-FACTOR FAMILY | BIOLOGY | REGULATORY T-CELLS | SJOGRENS-SYNDROME | ACTIVATING FACTOR | CUTTING EDGE | Encephalomyelitis, Autoimmune, Experimental - pathology | Encephalomyelitis, Autoimmune, Experimental - metabolism | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Cell Count | Humans | Mice, Inbred C57BL | Encephalomyelitis, Autoimmune, Experimental - immunology | Signal Transduction - genetics | Signal Transduction - immunology | Animals | B-Cell Activating Factor - metabolism | Th17 Cells - metabolism | B-Cell Activating Factor - genetics | Mice | Encephalomyelitis, Autoimmune, Experimental - genetics | B-Cell Activating Factor - deficiency | Receptors, Interleukin-6 - metabolism | Th17 Cells - pathology | B cells | T cells | Transforming growth factors | Cell differentiation | Multiple sclerosis | Encephalomyelitis | Disease | Helper cells | Nervous system | Lymphocytes T | Arthritis | Interleukin 6 | Antagonism | Lymphocytes | Rodents | Cell survival | Cytokines | Rheumatology | Stat3 protein | Cultures | Experimental allergic encephalomyelitis | CD4 antigen | Medicine | Hospitals | Lymphocytes B | BLyS protein | Collagen | Lymphomas | Autoimmune diseases | Index Medicus
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 04/2016, Volume 88, Issue 4, p. 712
  Inhibitor of nuclear factor kappa-B kinase Epsilon (IKK) is an IKK-related kinase. Despite it was originally discovered as a kinase functionally related to... 
Phosphorylation | Biochemistry | Kinases | Virology
Journal Article
Journal of Virology, ISSN 0022-538X, 02/2018, Volume 92, Issue 6
Journal Article
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 04/2016, Volume 88, Issue 4, pp. 712 - 718
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 06/2015, Volume 11, Issue 6
  Human gamma herpesviruses, including Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), are capable of inducing tumors,... 
Lymphomas | Genes | Rodents | Kaposis sarcoma | Viral infections
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 08/2015, Volume 15, Issue 6, pp. 519 - 532
Aberrant expression of the MDR1-encoded P-glycoprotein (P-gp) is often associated with clinical multi-drug resistance (MDR) leading to poor prognosis and... 
CBP | MDR1 | RNAi | Chromatin Immunoprecipitation | P300 | Wnt/β-catenin | SIDE POPULATION | KINASE PATHWAY | MESENCHYMAL TRANSITION | P-GLYCOPROTEIN | p300 | GROWTH-FACTOR-BETA | ONCOLOGY | Wnt/beta-catenin | MULTIPLE-DRUG RESISTANCE | GENE-EXPRESSION | FUNCTIONAL-ANALYSIS | MULTIDRUG-RESISTANCE | NF-KAPPA-B
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 04/2016, Volume 88, Issue 4, pp. 712 - 718
Journal Article
Cell Proliferation, ISSN 0960-7722, 10/2018, Volume 51, Issue 5, pp. e12464 - e12464
Journal Article