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1. Full Text Alterations in plasma membrane ion channel structures stimulate NLRP3 inflammasome activation in APOL1 risk milieu
by Jha, Alok and Kumar, Vinod and Haque, Shabirul and Ayasolla, Kamesh and Saha, Shourav and Lan, Xiqian and Malhotra, Ashwani and Saleem, Moin A and Skorecki, Karl and Singhal, Pravin C
The FEBS journal, ISSN 1742-464X, 05/2020, Volume 287, Issue 10, pp. 2000 - 2022
lipid bilayer | apolipoprotein L1 | K+‐efflux | pore structure | inflammasomes | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Residues | Membranes | Transcription | Interleukin | Insertion | Molecular dynamics | Risk | Lipids | Activation | Selectivity | Leucine | Nucleotides | Gene deletion | Lipid bilayers | Proteins | Alterations | Ion channels | Configurations | Bioinformatics | Efflux | Computer simulation | Ion transport | Apolipoproteins | Superposition (mathematics) | Membrane proteins | Domains | Pyrin protein | Plasma membranes | Mutation | Potassium | Pore formation | Index Medicus
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2. Full Text Disrupted apolipoprotein L1-miR193a axis dedifferentiates podocytes through autophagy blockade in an APOL1 risk milieu
by Kumar, Vinod and Ayasolla, Kamesh and Jha, Alok and Mishra, Abheepsa and Vashistha, Himanshu and Lan, Xiqian and Qayyum, Maleeha and Chinnapaka, Sushma and Purohit, Richa and Mikulak, Joanna and Saleem, Moin A and Malhotra, Ashwani and Skorecki, Karl and Singhal, Pravin C
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 08/2019, Volume 317, Issue 2, pp. C209 - C225
Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Tumor Suppressor Proteins - metabolism | Apolipoprotein L1 - metabolism | Podocytes - metabolism | Signal Transduction | Humans | Gene Expression Regulation | Cell Dedifferentiation | Apolipoprotein L1 - genetics | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Podocytes - pathology | Adaptor Proteins, Vesicular Transport - metabolism | Autophagy | Molecular Dynamics Simulation | Autophagosomes - pathology | Protein Interaction Maps | Phenotype | MicroRNAs - genetics | Autophagy-Related Proteins - metabolism | Cell Line, Transformed | TOR protein | Phosphorylation | Phenotypes | Immunoprecipitation | Transcription | U.V. radiation | Rapamycin | Apolipoproteins | 1-Phosphatidylinositol 3-kinase | Proteins | Alleles | Protein interaction | Phagocytosis | Index Medicus | miR193a | autophagy | APOL1 | podocytes | dedifferentiation of podocytes
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3. A novel role of the STAT3 pathway in brain inflammation-induced human neural progenitor cell differentiation
by Chen, E and Xu, D and Lan, X and Jia, B and Sun, L and Zheng, J.C and Peng, H
Current molecular medicine, ISSN 1566-5240, 2013, Volume 13, Issue 9, pp. 1474 - 1484
Inflammation | Differentiation | Neurogenesis | Neural progenitor cell | Cytokine | STAT3 | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine
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4. Full Text APOL1 polymorphism modulates sphingolipid profile of human podocytes
by Valsecchi, Manuela and Cazzetta, Valentina and Oriolo, Ferdinando and Lan, Xiqian and Piazza, Rocco and Saleem, Moin A and Singhal, Pravin C and Mavilio, Domenico and Mikulak, Joanna and Aureli, Massimo
Glycoconjugate journal, ISSN 0282-0080, 12/2020, Volume 37, Issue 6, pp. 729 - 744
Plasma membrane | Podocytes | APOL1 polymorphism | Lipid rafts | Sphingolipids | HIVAN | APOL1 | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Membrane lipids | Analysis | Sphingosine | Physiological aspects | Genetic aspects | Genetic polymorphisms | Globotriaosylceramide | Glycosphingolipids | DRM protein | Ceramide | Sphingomyelin | Labelling | Gene expression | Metabolism | Apolipoproteins | Radioactivity | Index Medicus | Original
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5. Full Text Transgenic silkworms (Bombyx mori) produce recombinant spider dragline silk in cocoons
by Wen, Hongxiu and Wen, Hongxiu and Lan, Xiqian and Lan, Xiqian and Zhang, Yuansong and Zhang, Yuansong and Zhao, Tianfu and Zhao, Tianfu and Wang, Yujun and Wang, Yujun and Kajiura, Zenta and Kajiura, Zenta and Nakagaki, Masao and Nakagaki, Masao
Molecular biology reports, ISSN 0301-4851, 4/2010, Volume 37, Issue 4, pp. 1815 - 1821
Life Sciences | Animal Biochemistry | Spider dragline silk | Mechanical characteristic | piggyBac | Cocoon proteins | Animal Anatomy / Morphology / Histology | Transgenic silkworm | PiggyBac | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Tensile Strength | Transformation, Genetic | Fibroins - biosynthesis | Animals, Genetically Modified | Electrophoresis, Polyacrylamide Gel | Fluorescence | Genotype | Materials Testing | Bombyx - genetics | Recombinant Proteins - biosynthesis | Genetic Vectors - genetics | Animals | Electrophoresis, Agar Gel | Spiders - metabolism | Animal Structures - metabolism | Luminescent Proteins - metabolism | Proteins | Biotechnology | Genetically engineered foods | Analysis | Polyamides | Genetic engineering | Universities and colleges | Food | Molecular biology | Transgenic animals | Worms | Tensile strength | Index Medicus
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6. Full Text APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress
by Wen, Hongxiu and Kumar, Vinod and Lan, Xiqian and Shoshtari, Seyedeh Shadafarin Marashi and Eng, Judith M and Zhou, Xiaogang and Wang, Fang and Wang, Haichao and Skorecki, Karl and Xing, Guolan and Wu, Guisheng and Luo, Huairong and Malhotra, Ashwani and Singhal, Pravin C
Bioscience reports, ISSN 0144-8463, 08/2018, Volume 38, Issue 4, p. 1
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Stresses | Phosphorylation | Immunoglobulins | Kidneys | Iodides | Toxicity | Translation initiation | Health risks | Propidium iodide | mRNA | Risk analysis | Gene expression | Apolipoproteins | Minority & ethnic groups | Risk factors | Stress | Necrosis | Proteins | Gangrene | NEPHRIN protein | Kidney diseases | Endoplasmic reticulum | Index Medicus
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7. Full Text A multiple-proxy stalagmite record reveals historical deforestation in central Shandong, northern China
by Tan, Liangcheng and Liu, Wen and Wang, Tianli and Cheng, Peng and Zang, Jingjie and Wang, Xiqian and Ma, Le and Li, Dong and Lan, Jianghu and Edwards, R. Lawrence and Cheng, Hai and Xu, Hai and Ai, Li and Gao, Yongli and Cai, Yanjun
Science China. Earth sciences, ISSN 1674-7313, 10/2020, Volume 63, Issue 10, pp. 1622 - 1632
Geosciences, Multidisciplinary | Physical Sciences | Geology | Science & Technology | Deforestation | Population growth | Calcium | Local precipitation | Human influences | Temperature variations | Climate control | Climate models | Climatic changes | Agricultural land | Anthropogenic factors | Mountains | Climate change | Precipitation | Stable isotopes | 15th century | Reclamation | Vegetation | Climate and vegetation | Vegetation changes | Trace elements | Farmlands | Isotopes
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8. Full Text VDR hypermethylation and HIV-induced T cell loss
by Nirupama Chandel and Mohammad Husain and Hersh Goel and Divya Salhan and Xiqian Lan and Ashwani Malhotra and Joseph McGowan and Pravin C. Singhal
Journal of leukocyte biology, ISSN 0741-5400, 04/2013, Volume 93, Issue 4, pp. 623 - 631
DNA methyltransferase | renin angiotensin system | double‐strand break | reactive oxygen species | Reactive oxygen species | Renin angiotensin system | Double-strand break | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | ras Proteins - genetics | Reactive Oxygen Species - metabolism | Catalase - antagonists & inhibitors | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Angiotensin II Type 1 Receptor Blockers - pharmacology | Receptors, Calcitriol - genetics | T-Lymphocytes - virology | DNA (Cytosine-5-)-Methyltransferases - metabolism | Calcitriol - analogs & derivatives | DNA Methylation | HIV-1 - physiology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Antimetabolites, Antineoplastic - pharmacology | T-Lymphocytes - pathology | Receptors, Calcitriol - antagonists & inhibitors | Catalase - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | ras Proteins - antagonists & inhibitors | Receptors, Calcitriol - metabolism | Catalase - metabolism | Azacitidine - pharmacology | DNA (Cytosine-5-)-Methyltransferases - genetics | Calcitriol - pharmacology | DNA Repair | CpG Islands | Lymphocyte Count | Apoptosis | Index Medicus | double-strand break | Host Defense & Pathophysiology
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9. Full Text Composite Membranes of Recombinant Silkworm Antimicrobial Peptide and Poly (L-lactic Acid) (PLLA) for biomedical application
by Li, Zhi and Liu, Xuan and Li, Yi and Lan, Xiqian and Leung, Polly Hangmei and Li, Jiashen and Li, Gang and Xie, Maobin and Han, Yanxia and Lin, Xiaofen
Scientific reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, pp. 31149 - 31149
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fungi | Membranes | Colon cancer | Wound healing | Antimicrobial peptides | Polylactic acid | Antibacterial activity | Skin | Parasites | Cancer | Immune system | Index Medicus
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10. Full Text High glucose enhances HIV entry into T cells through upregulation of CXCR4
by Xiqian Lan and Kang Cheng and Nirupama Chandel and Rivka Lederman and Aakash Jhaveri and Mohammad Husain and Ashwani Malhotra and Pravin C. Singhal
Journal of leukocyte biology, ISSN 0741-5400, 10/2013, Volume 94, Issue 4, pp. 769 - 777
HIF‐1α | receptors | antioxidants | ROS | Jurkat cells | enzymes | LTR | Antioxidants | Enzymes | Receptors | HIF-1α | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Gene Silencing - drug effects | Reactive Oxygen Species - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Jurkat Cells | Humans | RNA, Messenger - genetics | Hydrogen Peroxide - pharmacology | Oxidative Stress - genetics | Glucose - pharmacology | RNA, Messenger - metabolism | Virus Internalization - drug effects | T-Lymphocytes - virology | Receptors, CXCR4 - metabolism | Up-Regulation - drug effects | T-Lymphocytes - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Models, Biological | T-Lymphocytes - drug effects | Receptors, CXCR4 - genetics | Cell Membrane - metabolism | Oxidative Stress - drug effects | Cell Membrane - drug effects | Index Medicus | Receptors, Signal Transduction, & Genes
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