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Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1 - 18
Abstract Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for... 
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 07/2019, Volume 216, Issue 7, pp. 1542 - 1560
We demonstrated that an antibiotic cocktail (ABX)-perturbed gut microbiome is associated with reduced amyloid-beta (A beta) plaque pathology and astrogliosis... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | ALZHEIMERS-DISEASE | INFLAMMATION | BRAIN-DEVELOPMENT | GENDER | GUT MICROBIOTA | MODEL | IMMUNOLOGY | MATURATION | AGE | REVEALS
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 50, pp. 21435 - 21440
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 34, Issue 3, pp. 746 - 755
Journal Article
Scientific Reports, 12/2017, Volume 7, Issue 1, pp. 10411 - 10411
Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for neurodegenerative... 
Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 67, Issue 5, pp. 769 - 780
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 33, Issue 30, pp. 7605 - 7612
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 22, pp. 8534 - 8539
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 04/2013, Volume 53, Issue 4, pp. 335 - 344
► DIM inhibited Th2 responses in naive T cells via AhR signaling. ► DIM mediated reciprocal regulation of Th17 and Treg in naive T cells is AhR dependent. ►... 
Aryl hydrocarbon receptor | T regulatory cells | 3,3′-Diindolylmethane | T-helper cell | Ulcerative colitis | 3,3'-Diindolylmethane | CD4 T-CELLS | CROSS-REGULATORY LOOP | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3,3 '-Diindolylmethane | IMMUNOLOGY | GATA-3 | BREAST-CANCER CELLS | INFLAMMATORY-BOWEL-DISEASE | ARYL-HYDROCARBON RECEPTOR | MICE | INDOLE-3-CARBINOL | DIFFERENTIATION | EXPRESSION | Antigens, CD - immunology | Oxazolone | Male | Th2 Cells - immunology | Antigens, CD - genetics | Colitis, Ulcerative - immunology | Th2 Cells - drug effects | Intestinal Mucosa - drug effects | T-Lymphocytes, Regulatory - immunology | Th17 Cells - drug effects | Intestinal Mucosa - immunology | Receptors, Aryl Hydrocarbon - metabolism | Indoles - pharmacology | Colitis, Ulcerative - drug therapy | Disease Models, Animal | Antibodies, Monoclonal - pharmacology | Cells, Cultured | Colitis, Ulcerative - pathology | Gene Expression Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Colitis, Ulcerative - chemically induced | Th17 Cells - immunology | Indoles - therapeutic use | Mice | Mice, Inbred BALB C | Receptors, Aryl Hydrocarbon - immunology | Intestinal Mucosa - pathology | RNA | Estrogen | Biological response modifiers | Transforming growth factors | Sulfates | T cells | Cells | Dextran | Herbicides | Dioxin | Monoclonal antibodies | Interferon gamma | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 6748 - 6753
Understanding of the structure of the γ-secretase complex consisting of presenilin (PS), anterior pharynx-defective 1 (APH-1), nicastrin (NCT), and presenilin... 
nicastrin | substrate binding | Alzheimer disease | lid | gamma-secretase | Reports | Notch protein | amyloid precursor protein (APP) | mutagenesis
Journal Article
Organic Chemistry Frontiers, ISSN 2052-4110, 09/2017, Volume 4, Issue 9, pp. 1854 - 1857
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 08/2015, Volume 10, Issue 1
The [gamma]-secretase complex, composed of transmembrane proteins termed presenilin (PS), anterior pharynx defective (APH), nicastrin (NCT), and presenilin... 
Hydrolysis | Membrane lipids | Haptoglobin | Analysis | Amino acids | Catalysis | Cells | Membrane proteins
Journal Article
Scientific Reports (Nature Publisher Group), 09/2017, Volume 7, p. 1
Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for neurodegenerative... 
Animal models | Neurodegenerative diseases | Immunoregulation | Astrocytes | Lymphocytes T | Inflammation | Cerebrospinal fluid | Microglia | Gliosis | Antibiotics | Developmental stages | Presenilin 1 | Foxp3 protein | Amyloid | Amyloidosis | Alzheimer's disease
Journal Article
Journal Article