1994, 1-han., Nikkei bunko, ISBN 4532104998, Volume 497-498, v.
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4.
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Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
Nature, ISSN 0028-0836, 06/2011, Volume 474, Issue 7350, pp. 225 - 228
Induced pluripotent stem cells (iPSCs) are generated from somatic cells by the transgenic expression of three transcription factors collectively called OSK:...
PLURIPOTENT STEM-CELLS | PROTEIN | MYC | MULTIDISCIPLINARY SCIENCES | MOUSE | HUMAN FIBROBLASTS | STATE | GENERATION | Embryonic Stem Cells - metabolism | Receptors, Estrogen - metabolism | Embryonic Stem Cells - cytology | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Gene Expression Profiling | Nuclear Transfer Techniques | Cellular Reprogramming | DNA-Binding Proteins - metabolism | Epithelial-Mesenchymal Transition | Female | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Cell Line | Nanog Homeobox Protein | Cells, Cultured | Transcription Factors - metabolism | Animals | Genes, myc - genetics | Protein Binding | Fibroblasts - cytology | Mice | RNA-Binding Proteins - metabolism | Proteins | Cell division | Skin | Gene expression | Rodents
PLURIPOTENT STEM-CELLS | PROTEIN | MYC | MULTIDISCIPLINARY SCIENCES | MOUSE | HUMAN FIBROBLASTS | STATE | GENERATION | Embryonic Stem Cells - metabolism | Receptors, Estrogen - metabolism | Embryonic Stem Cells - cytology | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Gene Expression Profiling | Nuclear Transfer Techniques | Cellular Reprogramming | DNA-Binding Proteins - metabolism | Epithelial-Mesenchymal Transition | Female | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Cell Line | Nanog Homeobox Protein | Cells, Cultured | Transcription Factors - metabolism | Animals | Genes, myc - genetics | Protein Binding | Fibroblasts - cytology | Mice | RNA-Binding Proteins - metabolism | Proteins | Cell division | Skin | Gene expression | Rodents
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Pitfalls of DNA Quantification Using DNA-Binding Fluorescent Dyes and Suggested Solutions
PLOS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0150528
The Qubit fluorometer is a DNA quantification device based on the fluorescence intensity of fluorescent dye binding to double-stranded DNA (dsDNA). Qubit is...
DIAGNOSIS | ASSAY | MULTIDISCIPLINARY SCIENCES | QUANTITATION | CONDENSATION | GENOMIC DNA | PCR | BLOOD | Fluorescent Dyes - chemistry | Humans | Rats, Long-Evans | Organic Chemicals - chemistry | Rats | Real-Time Polymerase Chain Reaction - standards | Liver Neoplasms - chemistry | Formaldehyde | Liver - chemistry | Paraffin Embedding | DNA - chemistry | Animals | Fixatives | Solutions | DNA - analysis | Carcinoma, Hepatocellular - chemistry | High-Throughput Nucleotide Sequencing | Tissue Fixation | RNA | Genes | Liver | DNA | Genetic research | Fluorescence | Comparative analysis | Salts | Dyes | Single-stranded DNA | Laboratories | Fluorescent dyes | Fluorescent indicators | Paraffin | Tissues | Gene sequencing | Spectrum analysis | DNA fragmentation | Measurement methods | Electrophoresis | Trends | Deoxyribonucleic acid--DNA | Binding | Ethanol | Cloning | Distilled water | Sodium chloride | Gene expression | Ribonucleic acid--RNA | Polymerase chain reaction | Medicine | Pathology | Dilution | Quality control | Quality assessment | Methods | DNA sequencing | Deoxyribonucleic acid | Ribonucleic acid
DIAGNOSIS | ASSAY | MULTIDISCIPLINARY SCIENCES | QUANTITATION | CONDENSATION | GENOMIC DNA | PCR | BLOOD | Fluorescent Dyes - chemistry | Humans | Rats, Long-Evans | Organic Chemicals - chemistry | Rats | Real-Time Polymerase Chain Reaction - standards | Liver Neoplasms - chemistry | Formaldehyde | Liver - chemistry | Paraffin Embedding | DNA - chemistry | Animals | Fixatives | Solutions | DNA - analysis | Carcinoma, Hepatocellular - chemistry | High-Throughput Nucleotide Sequencing | Tissue Fixation | RNA | Genes | Liver | DNA | Genetic research | Fluorescence | Comparative analysis | Salts | Dyes | Single-stranded DNA | Laboratories | Fluorescent dyes | Fluorescent indicators | Paraffin | Tissues | Gene sequencing | Spectrum analysis | DNA fragmentation | Measurement methods | Electrophoresis | Trends | Deoxyribonucleic acid--DNA | Binding | Ethanol | Cloning | Distilled water | Sodium chloride | Gene expression | Ribonucleic acid--RNA | Polymerase chain reaction | Medicine | Pathology | Dilution | Quality control | Quality assessment | Methods | DNA sequencing | Deoxyribonucleic acid | Ribonucleic acid
Journal Article
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Pitfalls of DNA quantification using dnabinding fluorescent dyes and suggested solutions
PLoS ONE, 03/2016, Volume 11, Issue 3
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 17 - 14
Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous system. Foxp3(+) regulatory T (Treg) cells are reduced in frequency and...
HOMEOSTASIS | EXTRACELLULAR VESICLES | MULTIDISCIPLINARY SCIENCES | DISEASE | NEURODEGENERATION | MICRORNAS | DIFFERENTIATION | MICROPARTICLES | EXPRESSION | CANCER | FOXP3 | Multiple sclerosis | Clinics | Immunoregulation | Pathogenesis | Central nervous system | MiRNA | Lymphocytes T | Exosomes | Insulin | Patients | CD4 antigen | Lymphocytes | γ-Interferon | Foxp3 protein | Interferon | Growth factors
HOMEOSTASIS | EXTRACELLULAR VESICLES | MULTIDISCIPLINARY SCIENCES | DISEASE | NEURODEGENERATION | MICRORNAS | DIFFERENTIATION | MICROPARTICLES | EXPRESSION | CANCER | FOXP3 | Multiple sclerosis | Clinics | Immunoregulation | Pathogenesis | Central nervous system | MiRNA | Lymphocytes T | Exosomes | Insulin | Patients | CD4 antigen | Lymphocytes | γ-Interferon | Foxp3 protein | Interferon | Growth factors
Journal Article
The Plant Cell, ISSN 1040-4651, 1/2011, Volume 23, Issue 1, pp. 224 - 239
Intracellular Na⁺/H⁺ antiporters (NHXs) play important roles in cellular pH and Na⁺ and K⁺ homeostasis in all eukaryotes. Based on sequence similarity, the six...
Mesophyll cells | Cell growth | Cell walls | Epidermal cells | Root hairs | Plants | Antiporters | Vacuoles | Plant cells | Seedlings | VESICULAR TRAFFICKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | ION HOMEOSTASIS | VACUOLAR TRAFFICKING | VESICLE TRAFFICKING | PLANT SCIENCES | CELL BIOLOGY | TRANS-GOLGI NETWORK | GENE-EXPRESSION | H+-ATPASE | STRESS TOLERANCE | INCREASED SALT TOLERANCE | EXCHANGER | Arabidopsis Proteins - genetics | Oligonucleotide Array Sequence Analysis | Arabidopsis - growth & development | Stress, Physiological | Gene Expression Profiling | Phylogeny | RNA, Plant - genetics | Gene Knockout Techniques | Endosomes - metabolism | Arabidopsis - metabolism | Salinity | Sodium-Hydrogen Exchangers - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | trans-Golgi Network - metabolism | Gene Expression Regulation, Plant | Vacuoles - metabolism | Golgi Apparatus - metabolism | Sodium-Hydrogen Exchangers - genetics | Mutagenesis, Insertional
Mesophyll cells | Cell growth | Cell walls | Epidermal cells | Root hairs | Plants | Antiporters | Vacuoles | Plant cells | Seedlings | VESICULAR TRAFFICKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | ION HOMEOSTASIS | VACUOLAR TRAFFICKING | VESICLE TRAFFICKING | PLANT SCIENCES | CELL BIOLOGY | TRANS-GOLGI NETWORK | GENE-EXPRESSION | H+-ATPASE | STRESS TOLERANCE | INCREASED SALT TOLERANCE | EXCHANGER | Arabidopsis Proteins - genetics | Oligonucleotide Array Sequence Analysis | Arabidopsis - growth & development | Stress, Physiological | Gene Expression Profiling | Phylogeny | RNA, Plant - genetics | Gene Knockout Techniques | Endosomes - metabolism | Arabidopsis - metabolism | Salinity | Sodium-Hydrogen Exchangers - metabolism | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | trans-Golgi Network - metabolism | Gene Expression Regulation, Plant | Vacuoles - metabolism | Golgi Apparatus - metabolism | Sodium-Hydrogen Exchangers - genetics | Mutagenesis, Insertional
Journal Article
Hypertension Research, ISSN 0916-9636, 2014, Volume 37, Issue 4, pp. 253 - 390
Journal Article
Science, ISSN 0036-8075, 11/2003, Volume 302, Issue 5649, pp. 1408 - 1412
Individual cellular clocks in the suprachiasmatic nucleus (SCN), the circadian center, are integrated into a stable and robust pacemaker with a period length...
Bioluminescence | Amines | Neurons | Neuroglia | Genes | Luminescence | Schizophrenia | Reports | Mice | LSD | Behavioral neuroscience | IN-VITRO | CIRCADIAN-RHYTHMS | MULTIDISCIPLINARY SCIENCES | MOUSE | NEURONS | PACEMAKER | TETRODOTOXIN | BIOLOGICAL CLOCK | MPER1 GENE | Sodium - metabolism | Suprachiasmatic Nucleus - physiology | Neurons - physiology | Suprachiasmatic Nucleus - cytology | Transcription, Genetic | Protein Synthesis Inhibitors - pharmacology | Tetrodotoxin - pharmacology | Nuclear Proteins - genetics | Action Potentials - drug effects | Organ Culture Techniques | Basic Helix-Loop-Helix Transcription Factors | ARNTL Transcription Factors | Promoter Regions, Genetic | Gene Expression | Signal Transduction | Mice, Transgenic | Nuclear Proteins - metabolism | Circadian Rhythm - physiology | Glyceraldehyde-3-Phosphate Dehydrogenases - genetics | Period Circadian Proteins | Cycloheximide - pharmacology | Mice, Knockout | Transcription Factors - metabolism | Animals | CLOCK Proteins | Biological Clocks - physiology | Trans-Activators - metabolism | Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism | Cell Cycle Proteins | Suppression, Genetic | Circadian rhythms | Suprachiasmatic nucleus | Effect of chemicals on | Physiological aspects | Genetic aspects | Chemical properties | Research | Circadian rhythm | Mammals
Bioluminescence | Amines | Neurons | Neuroglia | Genes | Luminescence | Schizophrenia | Reports | Mice | LSD | Behavioral neuroscience | IN-VITRO | CIRCADIAN-RHYTHMS | MULTIDISCIPLINARY SCIENCES | MOUSE | NEURONS | PACEMAKER | TETRODOTOXIN | BIOLOGICAL CLOCK | MPER1 GENE | Sodium - metabolism | Suprachiasmatic Nucleus - physiology | Neurons - physiology | Suprachiasmatic Nucleus - cytology | Transcription, Genetic | Protein Synthesis Inhibitors - pharmacology | Tetrodotoxin - pharmacology | Nuclear Proteins - genetics | Action Potentials - drug effects | Organ Culture Techniques | Basic Helix-Loop-Helix Transcription Factors | ARNTL Transcription Factors | Promoter Regions, Genetic | Gene Expression | Signal Transduction | Mice, Transgenic | Nuclear Proteins - metabolism | Circadian Rhythm - physiology | Glyceraldehyde-3-Phosphate Dehydrogenases - genetics | Period Circadian Proteins | Cycloheximide - pharmacology | Mice, Knockout | Transcription Factors - metabolism | Animals | CLOCK Proteins | Biological Clocks - physiology | Trans-Activators - metabolism | Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism | Cell Cycle Proteins | Suppression, Genetic | Circadian rhythms | Suprachiasmatic nucleus | Effect of chemicals on | Physiological aspects | Genetic aspects | Chemical properties | Research | Circadian rhythm | Mammals
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 117 - 121
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes(1) of...
NGC 1275 | GALAXY CLUSTERS | TURBULENT VELOCITY | MULTIDISCIPLINARY SCIENCES | LINE | GAS | NGC-1275 | CONSTRAINTS | X-RAY SPECTROSCOPY | XMM-NEWTON | FEEDBACK | Clusters | Observations | Stars | Cosmology | Astrophysics | Velocity | Stars & galaxies | ASTRONOMY AND ASTROPHYSICS | GRQC | ASTRO
NGC 1275 | GALAXY CLUSTERS | TURBULENT VELOCITY | MULTIDISCIPLINARY SCIENCES | LINE | GAS | NGC-1275 | CONSTRAINTS | X-RAY SPECTROSCOPY | XMM-NEWTON | FEEDBACK | Clusters | Observations | Stars | Cosmology | Astrophysics | Velocity | Stars & galaxies | ASTRONOMY AND ASTROPHYSICS | GRQC | ASTRO
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Colorectal obstruction is a potential prognostic factor for stage II colorectal cancer
International Journal of Clinical Oncology, ISSN 1341-9625, 12/2018, Volume 23, Issue 6, pp. 1101 - 1111
Obstructive colorectal cancer (CRC) is an emergency situation with high morbidity and mortality, but long-term outcomes of stage II/III obstructive CRC remain...
Medicine & Public Health | Stage II | Colorectal cancer | Prognostic factor | Oncology | Cancer Research | Surgical Oncology | Colorectal obstruction | SURVIVAL | LEUCOVORIN | SURGICAL ADJUVANT BREAST | BOWEL OBSTRUCTION | OXALIPLATIN | FLUOROURACIL | CHEMOTHERAPY | COLON-CANCER | ONCOLOGY | HIGH-RISK | CARCINOMA | Colorectal Neoplasms - surgery | Intestinal Obstruction - etiology | Prognosis | Humans | Middle Aged | Male | Survival Rate | Neoplasm Recurrence, Local - diagnosis | Neoplasm Recurrence, Local - etiology | Aged, 80 and over | Colorectal Surgery - adverse effects | Female | Aged | Retrospective Studies | Colorectal Neoplasms - pathology | Intestinal Obstruction - diagnosis | Medical research | Gastrointestinal diseases | Analysis | Mortality | Adjuvant treatment | Medicine, Experimental | Health aspects | Cancer
Medicine & Public Health | Stage II | Colorectal cancer | Prognostic factor | Oncology | Cancer Research | Surgical Oncology | Colorectal obstruction | SURVIVAL | LEUCOVORIN | SURGICAL ADJUVANT BREAST | BOWEL OBSTRUCTION | OXALIPLATIN | FLUOROURACIL | CHEMOTHERAPY | COLON-CANCER | ONCOLOGY | HIGH-RISK | CARCINOMA | Colorectal Neoplasms - surgery | Intestinal Obstruction - etiology | Prognosis | Humans | Middle Aged | Male | Survival Rate | Neoplasm Recurrence, Local - diagnosis | Neoplasm Recurrence, Local - etiology | Aged, 80 and over | Colorectal Surgery - adverse effects | Female | Aged | Retrospective Studies | Colorectal Neoplasms - pathology | Intestinal Obstruction - diagnosis | Medical research | Gastrointestinal diseases | Analysis | Mortality | Adjuvant treatment | Medicine, Experimental | Health aspects | Cancer
Journal Article
Psychiatry and Clinical Neurosciences, ISSN 1323-1316, 06/2018, Volume 72, Issue 6, pp. 391 - 398
Aim The importance of early intervention in psychiatry is widely recognized among psychiatrists. However, it is unknown whether precise knowledge of at‐risk...
cognitive behavioral therapy | antipsychotics | diagnosis | at‐risk mental state | pharmacotherapy | at-risk mental state | DEPRESSION | EPA GUIDANCE | PSYCHIATRY | ULTRA-HIGH-RISK | NEUROSCIENCES | 1ST-EPISODE SCHIZOPHRENIA | CLINICAL NEUROLOGY | INDIVIDUALS | TRANSITION | ATTENUATED PSYCHOSIS SYNDROME | UNTREATED PSYCHOSIS | CLINICAL HIGH-RISK | ONSET | Surveys | Care and treatment | Behavioral health care | Cognitive therapy | Antipsychotic drugs | Clinical psychiatry | Psychiatrists | Schizophrenia | Behavior therapy | Psychosis | Neuroleptics | Patients
cognitive behavioral therapy | antipsychotics | diagnosis | at‐risk mental state | pharmacotherapy | at-risk mental state | DEPRESSION | EPA GUIDANCE | PSYCHIATRY | ULTRA-HIGH-RISK | NEUROSCIENCES | 1ST-EPISODE SCHIZOPHRENIA | CLINICAL NEUROLOGY | INDIVIDUALS | TRANSITION | ATTENUATED PSYCHOSIS SYNDROME | UNTREATED PSYCHOSIS | CLINICAL HIGH-RISK | ONSET | Surveys | Care and treatment | Behavioral health care | Cognitive therapy | Antipsychotic drugs | Clinical psychiatry | Psychiatrists | Schizophrenia | Behavior therapy | Psychosis | Neuroleptics | Patients
Journal Article
Review of Scientific Instruments, ISSN 0034-6748, 02/2019, Volume 90, Issue 2, p. 021702
PZT (lead zirconate titanate)-glued bimorph deformable mirrors are widely used in hard X-ray regimes; however, they have not yet been used in soft X-ray...
X-RAY MIRROR | INSTRUMENTS & INSTRUMENTATION | PHYSICS, APPLIED | OPTICS | Actuators | Deformable mirrors | Deformation | Vacuum chambers | Soft x rays | Formability | Bonding | High vacuum | Thermal stability | Substrates | Lead zirconate titanates
X-RAY MIRROR | INSTRUMENTS & INSTRUMENTATION | PHYSICS, APPLIED | OPTICS | Actuators | Deformable mirrors | Deformation | Vacuum chambers | Soft x rays | Formability | Bonding | High vacuum | Thermal stability | Substrates | Lead zirconate titanates
Journal Article
Circulation, ISSN 0009-7322, 11/2014, Volume 130, Issue 22
Journal Article
Journal of Infection and Chemotherapy, ISSN 1341-321X, 2013, Volume 19, Issue 3, pp. 393 - 403
Abstract The Japanese surveillance committee conducted the first nationwide surveillance of antimicrobial susceptibility patterns of uropathogens responsible...
Hematology, Oncology and Palliative Medicine | Resistance | Acute uncomplicated cystitis | Surveillance | Susceptibility | Medical Microbiology | Medicine & Public Health | Infectious Diseases | Virology | WOMEN | INFECTIOUS DISEASES | URINARY-TRACT-INFECTIONS | ECO.SENS | PHARMACOLOGY & PHARMACY | SPECTRUM BETA-LACTAMASES | Japan - epidemiology | Staphylococcus saprophyticus - drug effects | Escherichia coli - drug effects | Humans | Middle Aged | Cystitis - microbiology | Male | Microbial Sensitivity Tests | Escherichia coli - isolation & purification | Public Health Surveillance | Adolescent | Bacterial Infections - epidemiology | Staphylococcus saprophyticus - isolation & purification | Aged, 80 and over | Adult | Female | Aged | Anti-Bacterial Agents - pharmacology | Bacterial Infections - microbiology | Cystitis - epidemiology | Cystitis
Hematology, Oncology and Palliative Medicine | Resistance | Acute uncomplicated cystitis | Surveillance | Susceptibility | Medical Microbiology | Medicine & Public Health | Infectious Diseases | Virology | WOMEN | INFECTIOUS DISEASES | URINARY-TRACT-INFECTIONS | ECO.SENS | PHARMACOLOGY & PHARMACY | SPECTRUM BETA-LACTAMASES | Japan - epidemiology | Staphylococcus saprophyticus - drug effects | Escherichia coli - drug effects | Humans | Middle Aged | Cystitis - microbiology | Male | Microbial Sensitivity Tests | Escherichia coli - isolation & purification | Public Health Surveillance | Adolescent | Bacterial Infections - epidemiology | Staphylococcus saprophyticus - isolation & purification | Aged, 80 and over | Adult | Female | Aged | Anti-Bacterial Agents - pharmacology | Bacterial Infections - microbiology | Cystitis - epidemiology | Cystitis
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