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by Watanabe, Toshiaki and Watanabe, Toshiaki and Muro, Kei and Muro, Kei and Ajioka, Yoichi and Ajioka, Yoichi and Hashiguchi, Yojiro and Hashiguchi, Yojiro and Ito, Yoshinori and Ito, Yoshinori and Saito, Yutaka and Saito, Yutaka and Hamaguchi, Tetsuya and Hamaguchi, Tetsuya and Ishida, Hideyuki and Ishida, Hideyuki and Ishiguro, Megumi and Ishiguro, Megumi and Ishihara, Soichiro and Ishihara, Soichiro and Kanemitsu, Yukihide and Kanemitsu, Yukihide and Kawano, Hiroshi and Kawano, Hiroshi and Kinugasa, Yusuke and Kinugasa, Yusuke and Kokudo, Norihiro and Kokudo, Norihiro and Murofushi, Keiko and Murofushi, Keiko and Nakajima, Takako and Nakajima, Takako and Oka, Shiro and Oka, Shiro and Sakai, Yoshiharu and Sakai, Yoshiharu and Tsuji, Akihito and Tsuji, Akihito and Uehara, Keisuke and Uehara, Keisuke and Ueno, Hideki and Ueno, Hideki and Yamazaki, Kentaro and Yamazaki, Kentaro and Yoshida, Masahiro and Yoshida, Masahiro and Yoshino, Takayuki and Yoshino, Takayuki and Boku, Narikazu and Boku, Narikazu and Fujimori, Takahiro and Fujimori, Takahiro and Itabashi, Michio and Itabashi, Michio and Koinuma, Nobuo and Koinuma, Nobuo and Morita, Takayuki and Morita, Takayuki and Nishimura, Genichi and Nishimura, Genichi and Sakata, Yuh and Sakata, Yuh and Shimada, Yasuhiro and Shimada, Yasuhiro and Takahashi, Keiichi and Takahashi, Keiichi and Tanaka, Shinji and Tanaka, Shinji and Tsuruta, Osamu and Tsuruta, Osamu and Yamaguchi, Toshiharu and Yamaguchi, Toshiharu and Yamaguchi, Naohiko and Yamaguchi, Naohiko and Tanaka, Toshiaki and Tanaka, Toshiaki and Kotake, Kenjiro and Kotake, Kenjiro and Sugihara, Kenichi and Sugihara, Kenichi and Japanese Soc Canc Colon Rectum and Japanese Society for Cancer of the Colon and Rectum
International Journal of Clinical Oncology, ISSN 1341-9625, 2/2018, Volume 23, Issue 1, pp. 1 - 34
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 5, pp. 631 - 639
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49267
Fused in sarcoma/translocated in liposarcoma (FUS/TLS) is one of causative genes for familial amyotrophic lateral sclerosis (ALS). In order to identify binding... 
PRO-ONCOPROTEIN TLS/FUS | FUS | PRMT1 | TDP-43 | MULTIDISCIPLINARY SCIENCES | ALS | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | IDENTIFICATION | EXPRESSION | RNA-BINDING PROTEIN | Spinal Cord - drug effects | Spinal Cord - metabolism | Humans | Protein Transport - drug effects | Brain - metabolism | RNA-Binding Protein FUS - chemistry | Cell Nucleus - metabolism | Arsenites - toxicity | Cytoplasmic Granules - metabolism | Protein Binding - drug effects | HEK293 Cells | Protein Structure, Quaternary | Inclusion Bodies - metabolism | Motor Neurons - drug effects | Repressor Proteins - metabolism | Subcellular Fractions - drug effects | Cytoplasmic Granules - drug effects | Solubility | Inclusion Bodies - drug effects | RNA-Binding Protein FUS - metabolism | Detergents | Subcellular Fractions - metabolism | Protein-Arginine N-Methyltransferases - metabolism | Brain - drug effects | Motor Neurons - metabolism | Methylation - drug effects | Oxidative Stress - drug effects | Cell Nucleus - drug effects | Arginine - metabolism | Amyotrophic lateral sclerosis | Detergents, Synthetic | Genetic aspects | Arginine | Methylation | Transferases | Oxidative stress | Neurosciences | Yeast | Pathogenesis | Neurobiology | Inclusions | Nuclei | Proteins | FUS protein | Inclusion bodies | DNA methylation | Localization | Deoxyribonucleic acid--DNA | Binding | Adenosine | Fractionation | Sarcoma | Protein arginine methyltransferase | Metabolism | Mutants | Overexpression | Aggregates | Granular materials | Liposarcoma | Granules | Nuclei (cytology) | Mutation | Cytoplasm | Deoxyribonucleic acid | DNA
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 01/2020, Volume 10, Issue 1, pp. 820 - 14
The vertical occipital fasciculus (VOF) is an association fiber tract coursing vertically at the posterolateral corner of the brain. It is re-evaluated as a... 
ORGANIZATION | FIELD MAP CLUSTERS | INTEGRATION | MULTIDISCIPLINARY SCIENCES | FIBER TRACTOGRAPHY | PARCELLATION | PATTERNS | NEUROANATOMY | DEPTH | VISUAL AREAS | DORSAL | Knee | Brain | Autopsy | Neural networks | Vision | Cortex (occipital) | Visual pathways | Cortex (visual) | Substantia alba | Dissection
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9633 - 15
Baloxavir acid (BXA), derived from the prodrug baloxavir marboxil (BXM), potently and selectively inhibits the cap-dependent endonuclease within the polymerase... 
A VIRUS | NEURAMINIDASE | REFINEMENT | IN-VITRO | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | VALIDATION | CAP-BINDING | IDENTIFICATION | RNA-POLYMERASE | OSELTAMIVIR | Clinical trials | Viruses | Influenza A | Endonuclease | Influenza | Fitness
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 259 - 14
A novel EGFR-tyrosine kinase inhibitor (TKI), osimertinib, has marked efficacy in patients with EGFR-mutated lung cancer. However, some patients show intrinsic... 
TYROSINE KINASE INHIBITORS | BREAST-CANCER | HETEROGENEITY | LUNG-CANCER | ACTIVATION | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | ACQUIRED-RESISTANCE | LEUKEMIA-CELLS | MEDIATES RESISTANCE | EGFR | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Receptor, ErbB-3 - metabolism | Adenocarcinoma of Lung - pathology | Humans | Cell Survival - genetics | Male | Gene Knockdown Techniques | Neoplasm Recurrence, Local - pathology | Adenocarcinoma of Lung - genetics | Adenocarcinoma of Lung - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Cell Survival - drug effects | ErbB Receptors - antagonists & inhibitors | Piperazines - therapeutic use | Receptor, ErbB-3 - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Piperazines - pharmacology | Heterocyclic Compounds, 2-Ring - pharmacology | Drug Resistance, Neoplasm - genetics | Cell Line, Tumor | Mice, Inbred NOD | Mice | Mutation | RNA, Small Interfering - metabolism | Acrylamides | Aniline Compounds | ErbB Receptors - genetics | Lung Neoplasms - pathology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Heterocyclic Compounds, 2-Ring - therapeutic use | Adult | Female | Pyrazoles - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Lung - pathology | ErbB Receptors - metabolism | Neoplasm Recurrence, Local - prevention & control | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins - genetics | Treatment Outcome | Xenograft Model Antitumor Assays | Disease-Free Survival | Animals | Receptor Protein-Tyrosine Kinases - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Neoplasm Recurrence, Local - genetics | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Tyrosine | Cell survival | Epidermal growth factor receptors | Lung cancer | Feedback loops | Patients | Axl protein | Negative feedback | Inhibitors | Emergence | Inhibition | Viability | Protein-tyrosine kinase | Tumors | Cancer
Journal Article
Journal Article