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Lancet, The, ISSN 0140-6736, 2017, Volume 390, Issue 10089, pp. 29 - 39
Summary Background Alectinib, a potent, highly selective, CNS-active inhibitor of anaplastic lymphoma kinase (ALK), showed promising efficacy and tolerability... 
Internal Medicine | ANAPLASTIC LYMPHOMA KINASE | MEDICINE, GENERAL & INTERNAL | SAFETY | CH5424802 | AF-001JP | ADVANCED NSCLC | INHIBITORS | CHEMOTHERAPY | Single-Blind Method | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Piperidines - blood | Brain Neoplasms - secondary | Pyridines - adverse effects | Carcinoma, Non-Small-Cell Lung - secondary | Neoplasm Grading | Antineoplastic Agents - adverse effects | Pyrazoles - blood | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Carbazoles - blood | Pyrazoles - adverse effects | Pyridines - therapeutic use | Carcinoma, Non-Small-Cell Lung - pathology | Carbazoles - adverse effects | Lung Neoplasms - enzymology | Kaplan-Meier Estimate | Receptor Protein-Tyrosine Kinases - metabolism | Protein Kinase Inhibitors - blood | Pyridines - blood | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Piperidines - adverse effects | Antineoplastic Agents - blood | Aged | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Medical colleges | Respiratory agents | Care and treatment | Lymphomas | Lung cancer, Non-small cell | Product development | Pharmaceutical industry | Analysis | Toxicity | Funding | Lung cancer | Central nervous system | Medical services | Metastasis | Kinases | Recruitment | Motivation | Audio frequencies | Safety | Toxic diseases | Drug dosages | Protein-tyrosine kinase | Effectiveness | Cut-off | Data processing | Group dynamics | Patients | Survival | Lymphoma | Chemotherapy | Inhibitors | Interactive systems | Death | Mutation | Cancer | Pharmaceuticals
Journal Article
Journal of the Society of Powder Technology, Japan, ISSN 0386-6157, 05/2019, Volume 56, Issue 5, pp. 272 - 277
Journal Article
Journal of the Physical Society of Japan, ISSN 0031-9015, 04/2018, Volume 87, Issue 4, p. 044803
The mechanics of crawling cells on a substrate is investigated by using a minimal model that satisfies the force-free condition. A cell is described by two... 
Mechanics (physics) | Actuators | Cells | Substrates | Elongation | Cell adhesion & migration
Journal Article
ISSN 1744-683X, 1/2019, Volume 15, Issue 4, pp. 683 - 698
The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals, is crucial for the functioning of biological systems.... 
Journal Article
Soft Matter, ISSN 1744-683X, 01/2019, Volume 15, Issue 4, pp. 683 - 698
The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals, is crucial for the functioning of biological systems.... 
Computer simulation | Mechanical unloading | Unloading | Cell membranes | Adhesion | Substrates | Loads (forces) | Actin | Computer applications | Cytoskeleton | Mechanical stimuli | Cell size | Stretching
Journal Article
Computers and Fluids, ISSN 0045-7930, 01/2016, Volume 124, pp. 185 - 189
The Synchronized Molecular-Dynamics simulation, which was recently proposed by authors (Yasuda and Yamamoto, 2014), is applied to the analysis of polymer... 
Polymeric liquid | Lubrication | Viscous heating | Rheology | Multiscale modeling | Polymers | Molecular dynamics | Analysis | Electric properties | Liquids | Computer simulation | Heating | Parallel plates | Thermal conductivity | Heat transfer
Journal Article
Journal of the Physical Society of Japan, ISSN 0031-9015, 2018, Volume 87, Issue 4, p. 44803
The mechanics of crawling cells on a substrate is investigated by using a minimal model that satisfies the force-free condition. A cell is described by two... 
PHYSICS, MULTIDISCIPLINARY | SHAPE | MOTILITY
Journal Article
Journal of Chemical Physics, ISSN 0021-9606, 12/2013, Volume 139, Issue 23, p. 234105
An improved formulation of the "Smoothed Profile" method is introduced to perform direct numerical simulations of arbitrary rigid body dispersions in a... 
STOKES-FLOW | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | DYNAMICS | RESISTANCE | REYNOLDS-NUMBER FLOW | COLLOIDAL SUSPENSIONS | MOBILITY FUNCTIONS | HYDRODYNAMIC INTERACTIONS | Rigid structures | Tensors | Dispersions | Computer simulation | Direct numerical simulation | Friction | Mathematical analysis | Rigid-body dynamics | Mathematical models | Constraining
Journal Article
Nature Communications, ISSN 2041-1723, 05/2014, Volume 5, Issue 1, p. 3978
Journal Article
Journal of the Physical Society of Japan, ISSN 0031-9015, 10/2017, Volume 86, Issue 10, p. 101008_1
Swimming microorganisms, which include bacteria, algae, and spermatozoa, play a fundamental role in most biological processes. These swimmers are a special... 
Fluid mechanics | Profile method (forecasting) | Spermatozoa | Computer simulation | Computational fluid dynamics | Particle collisions | Reynolds number | Fluid flow | Hydrodynamics | Time | Dispersions | Phase transitions | Biological activity | Tracer particles | Microorganisms | Dynamic tests | Simulation | Bacteria | Swimming | Confining | Diffusion | Walls | Cylinders
Journal Article
Journal of the Physical Society of Japan, ISSN 0031-9015, 02/2013, Volume 82, Issue 2, pp. 1 - 1
Direct numerical simulations were performed using a smooth profile method to investigate the steady-state sedimentation of monodisperse spherical particles in... 
Peclet number | Computational fluid dynamics | Anisotropy | Fluctuation | Fluid flow | Hydrodynamics | Diffusion | Sedimentation
Journal Article
Journal of the Physical Society of Japan, ISSN 0031-9015, 02/2013, Volume 82, Issue 2, p. 1
  Direct numerical simulations were performed using a smooth profile method to investigate the steady-state sedimentation of monodisperse spherical particles... 
Fluid mechanics | Anisotropy | Particle physics | Spheres | Diffusion | Navier Stokes equations | Velocity
Journal Article
Physical Review Letters, ISSN 0031-9007, 1998, Volume 81, Issue 22, pp. 4915 - 4918
The diffusivity of tagged particles is demonstrated to be heterogeneous on time scales comparable to or less than the stress relaxation time congruent to... 
TRANSITION | GLASS-FORMING LIQUIDS | MOLECULAR-DYNAMICS | NEUTRON-SPIN-ECHO | PHYSICS, MULTIDISCIPLINARY | SUSCEPTIBILITY | POLYBUTADIENE
Journal Article
Soft Matter, ISSN 1744-683X, 6/2018, Volume 14, Issue 22, pp. 452 - 4529
The field induced anisotropic interactions between like-charged colloidal particles is studied using direct numerical simulations, where the polarization of... 
DISPERSIONS | POLYMER SCIENCE | PARTICLE | PHYSICS, MULTIDISCIPLINARY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | DOUBLE-LAYER | Electric double layer | Attraction | Computer simulation | Debye length | Zeta potential | Colloids | Charged particles
Journal Article
by Mahajan, Anubha and Go, Min Jin and Zhang, Weihua and Below, Jennifer E and Gaulton, Kyle J and Ferreira, Teresa and Horikoshi, Momoko and Johnson, Anew D and Ng, Maggie C. Y and Prokopenko, Inga and Saleheen, Danish and Wang, Xu and Zeggini, Eleftheria and Abecasis, Goncalo R and Adair, Linda S and Almgren, Peter and Atalay, Mustafa and Aung, Tin and Baldassarre, Damiano and Balkau, Beverley and Bao, Yuqian and Barnett, Anthony H and Barroso, Ines and Basit, Abdul and Been, Latonya F and Beilby, John and Bell, Graeme I and Benediktsson, Rafn and Bergman, Richard N and Boehm, Bernhard O and Boerwinkle, Eric and Bonnycastle, Lori L and Burtt, Noël and Cai, Qiuyin and Campbell, Harry and Carey, Jason and Cauchi, Stephane and Caulfield, Mark and Chan, Juliana C. N and Chang, Li-Ching and Chang, Tien-Jyun and Chang, Yi-Cheng and Charpentier, Guillaume and Chen, Chien-Hsiun and Chen, Han and Chen, Yuan-Tsong and Chia, Kee-Seng and Chidambaram, Manickam and Hovingh, Kees and Trip, Mieke D and South Asian Type Diabet SAT2D Cons and DIAbet Genetics Replication & Meta and Mexican Amer Type 2 Diabet MAT2D C and Asian Genetic Epidemiology Network and Type 2 Diabet Genetic Exploration and South Asian Type 2 Diabetes (SAT2D) Consortium and Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium and Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium and DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Mexican American Type 2 Diabetes (MAT2D) Consortium and Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 3, pp. 234 - 244
Journal Article
Geochemistry, Geophysics, Geosystems, ISSN 1525-2027, 11/2019, Volume 20, Issue 11, pp. 5319 - 5333
Speciation analysis of Fe in single plagioclase crystals separated from two different gabbros was performed to understand the crystallization mechanisms of... 
magnetite exsolution | iron | plagioclase | XAFS
Journal Article
Nature Communications, ISSN 2041-1723, 01/2015, Volume 6, Issue 1, p. 6089
Among the key challenges to our understanding of solidification in the glass transition is that it is accompanied by little apparent change in structure.... 
HETEROGENEITY | DYNAMICS | SCALES | GROWING LENGTH | MULTIDISCIPLINARY SCIENCES | SUPERCOOLED LIQUIDS
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2011, Volume 43, Issue 6, pp. 531 - 538
Journal Article