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SAE technical paper series, Volume 2015-01-1469.
Multibody human models are widely used to investigate responses of human during an automotive crash. This study aimed to validate a commercially available... 
Pedestrian injuries | Kinematics
eJournal
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 505 - 509
Mutationally activated kinases define a clinically validated class of targets for cancer drug therapy(1). However, the efficacy of kinase inhibitors in... 
CELL LUNG-CANCER | SURVIVAL | HETEROGENEITY | ACTIVATION | RECEPTOR TYROSINE KINASES | THERAPY | MET AMPLIFICATION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | SENSITIVITY | TUMOR-CELLS | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Melanoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Hepatocyte Growth Factor - pharmacology | Breast Neoplasms - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Antimitotic agents | Physiological aspects | Antineoplastic agents | Growth factors | Health aspects | Phosphotransferases | Substance abuse treatment | Epidermal growth factor | Rodents | Biomarkers | Breast cancer | Insulin-like growth factors | Kinases | Drug resistance | Tumors | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0125625 - e0125625
Journal Article
Journal Article
Journal of Global Optimization, ISSN 0925-5001, 2019, pp. 1 - 26
Multi-source Weber problem (MSWP) is a classical nonconvex and NP-hard model in facility location. A well-known method for solving MSWP is the... 
Multi-source Weber problem | ADMM | Nonconvex | Location–allocation | Gauge | Distance measurement | Algorithms | Constraints | Iterative methods
Journal Article
Thorax, ISSN 0040-6376, 2018, Volume 74, Issue 3, pp. 305 - 308
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2012, Volume 18, Issue 6, p. 854
  Metastatic colorectal cancer is a largely incurable disease with a pressing need for targeted therapies. A new study sheds light on a surprising interaction... 
Proteins | Metastasis | Cancer therapies | Colorectal cancer
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 07/2013, Volume 9, Issue 1, pp. 673 - n/a
The epidermal growth factor receptor (EGFR) signaling network is activated in most solid tumors, and small‐molecule drugs targeting this network are... 
mathematical modeling | modular response analysis | EGFR signaling | cancer | signal transduction | PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | ERK ACTIVATION | CELL-DEATH | REGULATED KINASE | COLON-CANCER | GROWTH | KRAS | NEGATIVE FEEDBACK | AZD6244 ARRY-142886 | Receptor, Epidermal Growth Factor - genetics | ras Proteins - genetics | Protein Interaction Maps - drug effects | Colorectal Neoplasms - genetics | Humans | ras Proteins - metabolism | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | Receptor, Epidermal Growth Factor - metabolism | Colorectal Neoplasms - drug therapy | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Drug Therapy, Combination | Proto-Oncogene Proteins c-akt - metabolism | Colorectal Neoplasms - metabolism | Proto-Oncogene Proteins B-raf - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Mice, Nude | Proto-Oncogene Proteins B-raf - genetics | Cell Line, Tumor | Mice | Models, Genetic | Protein Kinase Inhibitors - pharmacology | Colorectal Neoplasms - pathology | Drug Screening Assays, Antitumor | Index Medicus
Journal Article
Journal Article
Journal of Materials Chemistry A, ISSN 2050-7488, 05/2015, Volume 3, Issue 17, pp. 9116 - 9122
Journal Article