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Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10086, pp. 2287 - 2303
Summary Background Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks signalling of interleukin 4 and interleukin 13, type 2/Th2 cytokines... 
Internal Medicine | DAILY PRACTICE COHORT | ADULT PATIENTS | DRUG SURVIVAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE-A | THERAPY | CLINICAL-TRIAL | ECZEMA | GUIDELINES | COATED MYCOPHENOLATE SODIUM | PERSISTENT ASTHMA | Severity of Illness Index | Double-Blind Method | Anti-Asthmatic Agents - therapeutic use | United States | Humans | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Adrenal Cortex Hormones - therapeutic use | Dermatitis, Atopic - drug therapy | Injections, Subcutaneous | Adult | Female | Drug Therapy, Combination | Medical research | Medical colleges | Corticosteroids | Interleukins | Atopic dermatitis | Clinical trials | Monoclonal antibodies | Medicine, Experimental | Product development | Pharmaceutical industry | Analysis | Corticoids | Pathogenesis | Funding | Calcineurin | Interleukin | Calcineurin inhibitors | Lymphocytes T | Allergic diseases | Conjunctivitis | Immunoglobulin A | Dermatitis | Institutions | Acceptability | Interleukin 4 | Eczema | Skin diseases | Safety | Drug therapy | Signs and symptoms | Effectiveness | Cytokines | Dermatology | Cut-off | Abnormalities | Interleukin 13 | Management | Injection | Patients | Diseases | Asthma | Hospitals | Inhibitors | Interactive systems | Adults | Voice | Pharmaceuticals | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
Ophthalmology, ISSN 0161-6420, 2012, Volume 119, Issue 12, pp. 2537 - 2548
Journal Article
Journal Article
Ophthalmology, ISSN 0161-6420, 2014, Volume 121, Issue 11, pp. 2247 - 2254
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 2, pp. 130 - 139
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2018, Volume 378, Issue 26, pp. 2486 - 2496
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 6, pp. 1293 - 1300
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 3, pp. 211 - 221
Loss-of-function variants in ANGPTL3 were associated with lower plasma levels of lipids and lower rates of coronary disease. A monoclonal antibody against... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | IMMUNOGLOBULIN GENES | ATHEROSCLEROSIS | RISK | CORONARY-ARTERY-DISEASE | FAMILIAL COMBINED HYPOLIPIDEMIA | LIPOPROTEIN-LIPASE GENE | TRANSGENIC MICE | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Angiopoietins - antagonists & inhibitors | Dose-Response Relationship, Drug | Dyslipidemias - blood | Angiopoietin-like Proteins | Lipids - blood | Female | Disease Models, Animal | Dyslipidemias - drug therapy | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Coronary Artery Disease - metabolism | Mice, Inbred Strains | Atherosclerosis - metabolism | Animals | Antibodies, Monoclonal - administration & dosage | Coronary Artery Disease - genetics | Lipid Metabolism - drug effects | Aged | Mice | Mutation | Angiopoietins - genetics | Cholesterol, LDL | Research | Antibiosis | Atherosclerosis | Lipoproteins (low density) | Medical research | Angiopoietin | Genomics | Genes | Coronary artery | Triglycerides | Biochemistry | Gene expression | Cholesterol | Serum levels | Proteins | Antagonism | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Heart diseases | Drug dosages | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 12, pp. 1108 - 1118
A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial... 
POPULATION | MEDICINE, GENERAL & INTERNAL | STATIN | MICE | MUTATIONS | Proprotein Convertases - antagonists & inhibitors | Injections, Intravenous | Heptanoic Acids - therapeutic use |