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1. Full Text Hepatobiliary and Pancreatic: Caroli syndrome: Egg-like sign on CT
by Zhong, Yandan and Peng, Shanshan and Yang, Yongfeng
Journal of gastroenterology and hepatology, ISSN 0815-9319, 09/2019
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2. Full Text Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma
by Wilson, Wyndham H and Young, Ryan M and Schmitz, Roland and Yang, Yandan and Pittaluga, Stefania and Wright, George and Lih, Chih-Jian and Williams, P Mickey and Shaffer, Arthur L and Gerecitano, John and De Vos, Sven and Goy, Andre and Kenkre, Vaishalee P and Barr, Paul M and Blum, Kristie A and Shustov, Andrei and Advani, Ranjana and Fowler, Nathan H and Vose, Julie M and Elstrom, Rebecca L and Habermann, Thomas M and Barrientos, Jacqueline C and McGreivy, Jesse and Fardis, Maria and Chang, Betty Y and Clow, Fong and Munneke, Brian and Moussa, Davina and Beaupre, Darrin M and Staudt, Louis M
Nature Medicine, ISSN 1078-8956, 08/2015, Volume 21, Issue 8, pp. 922 - 926
The two major subtypes of diffuse large B cell lymphoma (DLBCL)-activated B cell-like (ABC) and germinal center B cell-like (GCB)-arise by distinct mechanisms,... 
PATHOGENESIS | MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | BTK | CHRONIC LYMPHOCYTIC-LEUKEMIA | MUTATIONS | NF-KAPPA-B | CELL BIOLOGY | Lymphoma, Large B-Cell, Diffuse - drug therapy | Humans | Middle Aged | Myeloid Differentiation Factor 88 - genetics | Molecular Sequence Data | Male | Pyrimidines - pharmacology | Lymphoma, Large B-Cell, Diffuse - mortality | Signal Transduction - drug effects | Base Sequence | Adult | Female | Receptors, Antigen, B-Cell - physiology | Aged | Protein Kinase Inhibitors - pharmacology | CD79 Antigens - genetics | Mutation | Lymphoma, Large B-Cell, Diffuse - genetics | Pyrazoles - pharmacology | Signal transduction | Chemotherapy | Lymphomas | Pharmacology | Lymphocytes
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3. Full Text Oncogenically active MYD88 mutations in human lymphoma
by Ngo, Vu N and Young, Ryan M and Schmitz, Roland and Jhavar, Sameer and Xiao, Wenming and Lim, Kian-Huat and Kohlhammer, Holger and Xu, Weihong and Yang, Yandan and Zhao, Hong and Shaffer, Arthur L and Romesser, Paul and Wright, George and Powell, John and Rosenwald, Andreas and Muller-Hermelink, Hans Konrad and Ott, German and Gascoyne, Randy D and Connors, Joseph M and Rimsza, Lisa M and Campo, Elias and Jaffe, Elaine S and Delabie, Jan and Smeland, Erlend B and Fisher, Richard I and Braziel, Rita M and Tubbs, Raymond R and Cook, J.R and Weisenburger, Denny D and Chan, Wing C and Staudt, Louis M
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7332, pp. 115 - 121
The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) remains the least curable form of this malignancy despite recent advances in... 
TNFAIP3 A20 | PATHWAYS | SURVIVAL | B-CELL LYMPHOMA | GENE | SIGNATURES | SUBTYPES | MULTIDISCIPLINARY SCIENCES | KINASE | INHIBITORS | NF-KAPPA-B | Interleukin-1 Receptor-Associated Kinases - metabolism | Phosphorylation | Interleukin-1 Receptor-Associated Kinases - genetics | Interleukin-1 Receptor-Associated Kinases - biosynthesis | Humans | Molecular Sequence Data | NF-kappa B - metabolism | Janus Kinases - metabolism | Myeloid Differentiation Factor 88 - chemistry | RNA Interference | Burkitt Lymphoma - genetics | Toll-Like Receptors - metabolism | STAT3 Transcription Factor - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Oncogenes - genetics | Cytokines - metabolism | Lymphoma, Large B-Cell, Diffuse - pathology | Signal Transduction | Cell Survival | Cytokines - secretion | Mutant Proteins - genetics | Myeloid Differentiation Factor 88 - genetics | Mutant Proteins - metabolism | Mutation - genetics | Lymphoma, B-Cell, Marginal Zone - genetics | Receptors, Interleukin-1 - metabolism | Sequence Analysis, RNA | Lymphoma, Large B-Cell, Diffuse - classification | Mutant Proteins - chemistry | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | High-Throughput Nucleotide Sequencing | Lymphoma, Large B-Cell, Diffuse - genetics | Myeloid Differentiation Factor 88 - metabolism | Amino Acid Substitution | Lymphomas | Genetic aspects | Models | Gene mutations | Observations | Abnormalities | Mutation | Kinases | Toxicity | Apoptosis | Tumors
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4. Full Text Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma
by Schmitz, Roland and Wright, George W and Huang, Da Wei and Johnson, Calvin A and Phelan, James D and Wang, James Q and Roulland, Sandrine and Kasbekar, Monica and Young, Ryan M and Shaffer, Arthur L and Hodson, Daniel J and Xiao, Wenming and Yu, Xin and Yang, Yandan and Zhao, Hong and Zhao, Yongmei and Xu, Weihong and Liu, Xuelu and Zhou, Bin and Du, Wei and Chan, Wing C and Jaffe, Elaine S and Gascoyne, Randy D and Connors, Joseph M and Campo, Elias and Lopez-Guillermo, Armando and Rosenwald, Andreas and Ott, German and Delabie, Jan and Rimsza, Lisa M and Tay Kuang Wei, Kevin and Zelenetz, Andrew D and Leonard, John P and Bartlett, Nancy L and Tran, Bao and Shetty, Jyoti and Soppet, Dan R and Pittaluga, Stefania and Wilson, Wyndham H and Staudt, Louis M
The New England Journal of Medicine, ISSN 0028-4793, 04/2018, Volume 378, Issue 15, pp. 1396 - 1407
Gene-expression profiling of 574 cases of diffuse large B-cell lymphoma revealed four new subtypes based on the co-occurrence of mutation patterns. The... 
PRIMARY CNS LYMPHOMA | SURVIVAL | MEDICINE, GENERAL & INTERNAL | ACTIVATION | BRUTON TYROSINE KINASE | RECEPTOR LEVELS | SIGNATURES | IBRUTINIB | MARGINAL ZONE LYMPHOMA | EXPRESSION | GENOME | Genetic aspects | Research | Lymphocytic leukemia | Cancer | Translocation | Medical research | Biomedical research | Laboratories | Pathogenesis | Event-related potentials | B-cell receptor | Gene expression | Cancer therapies | Medicine | Pathology | Chemotherapy | Lymphocytes B | Biopsy | Genetic analysis | Classification | Lymphomas | Mutation | Deoxyribonucleic acid--DNA | DNA sequencing | Bcl-6 protein | B-cell lymphoma | Genetics | Genètica | Cèl·lules B | Limfomes | B cells
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5. Full Text Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
by Schmitz, Roland and Young, Ryan M and Ceribelli, Michele and Jhavar, Sameer and Xiao, Wenming and Zhang, Meili and Wright, George and Shaffer, Arthur L and Hodson, Daniel J and Buras, Eric and Liu, Xuelu and Powell, John and Yang, Yandan and Xu, Weihong and Zhao, Hong and Kohlhammer, Holger and Rosenwald, Aneas and Kluin, Philip and Mueller-Hermelink, Hans Konrad and Ott, German and Gascoyne, Randy D and Connors, Joseph M and Rimsza, Lisa M and Campo, Elias and Jaffe, Elaine S and Delabie, Jan and Smeland, Erlend B and Ogwang, Martin D and Reynolds, Steven J and Fisher, Richard I and Braziel, Rita M and Tubbs, Raymond R and Cook, James R and Weisenburger, Dennis D and Chan, Wing C and Pittaluga, Stefania and Wilson, Wyndham and Waldmann, Thomas A and Rowe, Martin and Mbulaiteye, Sam M and Rickinson, Alan B and Staudt, Louis M
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7418, pp. 116 - 120
Burkitt's lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such therapy precludes its use in the elderly and in patients with... 
IMMUNOGLOBULIN | CELL | MULTIDISCIPLINARY SCIENCES | REGION | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Genomics | Humans | Inhibitor of Differentiation Proteins - genetics | Burkitt Lymphoma - metabolism | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Cyclin-Dependent Kinase 6 - metabolism | Inhibitor of Differentiation Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Receptors, Antigen, B-Cell - metabolism | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Burkitt Lymphoma - pathology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Cycle | RNA Interference | Cyclin D3 - genetics | Genes, myc - genetics | Burkitt Lymphoma - genetics | High-Throughput Nucleotide Sequencing | Neoplasm Proteins - genetics | Burkitt Lymphoma - drug therapy | Cyclin D3 - metabolism | RNA sequencing | Usage | Care and treatment | Gene mutations | Observations | Identification and classification | Burkitt's lymphoma | Chemotherapy | Pathogenesis | Toxicity | Mutation | Kinases | Crystal structure
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6. Full Text MiR-21 Indicates Poor Prognosis in Tongue Squamous Cell Carcinomas as an Apoptosis Inhibitor
by Jinsong Li and Hongzhang Huang and Lijuan Sun and Mei Yang and Chaobin Pan and Weiliang Chen and Donghui Wu and Zhaoyu Lin and Chunxian Zeng and Yandan Yao and Peter Zhang and Erwei Song
Clinical Cancer Research, ISSN 1078-0432, 06/2009, Volume 15, Issue 12, pp. 3998 - 4008
Purpose: We aim to examine miR-21 expression in tongue squamous cell carcinomas (TSCC) and correlate it with patient clinical status, and to investigate its... 
apoptosis | miR-21 | prognosis | TPM1 | tongue squamous cell carcinoma | EXPRESSION PATTERNS | BREAST-CANCER CELLS | HEPATOCELLULAR-CARCINOMA | HUMAN LUNG CANCERS | ANOIKIS | ONCOLOGY | TUMOR-SUPPRESSOR GENE | TROPOMYOSIN-1 | MICRORNA-21 TARGETS | C-ELEGANS | COLON ADENOCARCINOMA | Tropomyosin - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | MicroRNAs - metabolism | Gene Knockdown Techniques | Carcinoma, Squamous Cell - mortality | Transfection | Microarray Analysis | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Tongue Neoplasms - metabolism | Tropomyosin - metabolism | Tongue Neoplasms - mortality | Cell Line | Oligonucleotides, Antisense - pharmacology | Kaplan-Meier Estimate | PTEN Phosphohydrolase - metabolism | Tongue Neoplasms - pathology | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Aged | Mice | Apoptosis | RNA, Small Interfering - metabolism
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7. Full Text Functional proteogenomic screens in multiple myeloma
by Young, Ryan and Yang, Yandan and Oellerich, Thomas
Clinical Lymphoma, Myeloma and Leukemia, ISSN 2152-2650, 10/2019, Volume 19, Issue 10, pp. e112 - e112
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8. Full Text Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
by Davis, R. Eric and Ngo, Vu N and Lenz, Georg and Tolar, Pavel and Young, Ryan M and Romesser, Paul B and Kohlhammer, Holger and Lamy, Laurence and Zhao, Hong and Yang, Yandan and Xu, Weihong and Shaffer, Arthur L and Wright, George and Xiao, Wenming and Powell, John and Jiang, Jian-Kang and Thomas, Craig J and Rosenwald, Andreas and Ott, German and Muller-Hermelink, Hans Konrad and Gascoyne, Randy D and Connors, Joseph M and Johnson, Nathalie A and Rimsza, Lisa M and Campo, Elias and Jaffe, Elaine S and Wilson, Wyndham H and Delabie, Jan and Smeland, Erlend B and Fisher, Richard I and Braziel, Rita M and Tubbs, Raymond R and Cook, J.R and Weisenburger, Dennis D and Chan, Wing C and Pierce, Susan K and Staudt, Louis M
Nature, ISSN 0028-0836, 01/2010, Volume 463, Issue 7277, pp. 88 - 92
A role for B-cell-receptor (BCR) signalling in lymphomagenesis has been inferred by studying immunoglobulin genes in human lymphomas(1,2) and by engineering... 
SURVIVAL | TARGET | INTERNALIZATION | INITIATION | MOLECULE | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN | INHIBITORS | ANTIGEN RECEPTOR | IG-ALPHA | CD79 Antigens - chemistry | Protein-Tyrosine Kinases - metabolism | Receptors, Antigen, B-Cell - deficiency | Humans | Lymphoma, Large B-Cell, Diffuse - metabolism | Receptors, Antigen, B-Cell - metabolism | CARD Signaling Adaptor Proteins - genetics | CARD Signaling Adaptor Proteins - metabolism | Protein-Tyrosine Kinases - genetics | RNA Interference | src-Family Kinases - metabolism | Cell Membrane - metabolism | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Lymphoma, Large B-Cell, Diffuse - pathology | Signal Transduction | Cell Survival | Guanylate Cyclase - metabolism | Amino Acid Motifs | CD79 Antigens - metabolism | Cell Line, Tumor | Guanylate Cyclase - genetics | Receptors, Antigen, B-Cell - genetics | CD79 Antigens - genetics | Mutation | Lymphoma, Large B-Cell, Diffuse - genetics | Immunoglobulins | Gene mutations | Development and progression | Lymphomas | Genetic aspects | B cells | Research | Properties | Health aspects | Cancer | Proteins | Kinases | Gene expression | Toxicity | Apoptosis
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9. Full Text Production and characterization of lignin containing nanocellulose from luffa through an acidic deep eutectic solvent treatment and systematic fractionation
by Hong, Shu and Song, Yandan and Yuan, Yang and Lian, Hailan and Liimatainen, Henrikki
Industrial Crops and Products, ISSN 0926-6690, 01/2020, Volume 143, p. 111913
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10. Full Text Role of RNA secondary structures in regulating Dscam alternative splicing
by Xu, Bingbing and Shi, Yang and Wu, Yandan and Meng, Yijun and Jin, Yongfeng
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, ISSN 1874-9399, 04/2019, p. 194381
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11. Full Text Approximate Order-Sensitive k-NN Queries over Correlated High-Dimensional Data
by Gu, Yu and Guo, Yandan and Song, Yang and Zhou, Xiangmin and Yu, Ge
IEEE Transactions on Knowledge and Data Engineering, ISSN 1041-4347, 11/2018, Volume 30, Issue 11, pp. 2037 - 2050
The k Nearest Neighbor ( k -NN) query has been gaining more importance in extensive applications involving information retrieval, data mining, and databases.... 
Dimensionality reduction | Correlation | Data preprocessing | high-dimensional data | Gaussian distribution | k -nearest neighbor query">k -nearest neighbor query | Indexes | Data mining | Approximate query | order-sensitive | Principal component analysis | k-nearest neighbor query | correlation | SEARCH | COMPUTER SCIENCE, INFORMATION SYSTEMS | NEAREST-NEIGHBOR QUERIES | COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE | ENGINEERING, ELECTRICAL & ELECTRONIC | Basic input-output system | Pruning | Information retrieval | Queries | Efficiency
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12. Full Text Efficient conversion of acetate into lipids by the oleaginous yeast Cryptococcus curvatus
by Gong, Zhiwei and Shen, Hongwei and Zhou, Wengting and Wang, Yandan and Yang, Xiaobing and Zhao, Zongbao K
Biotechnology for Biofuels, ISSN 1754-6834, 11/2015, Volume 8, Issue 1, p. 189
Background: Acetic acid is routinely generated during lignocelluloses degradation, syngas fermentation, dark hydrogen fermentation and other anaerobic... 
Microbial lipids | Oleaginous yeast | Continuous culture | Acetic acid | Biodiesel | Biomass hydrolysates | Cryptococcus curvatus | SYNTHESIS GAS | YARROWIA-LIPOLYTICA | BIOFUEL PRODUCTION | ENERGY & FUELS | BATCH CULTURE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RHODOSPORIDIUM-TORULOIDES | CANDIDA-CURVATA | CELL OIL PRODUCTION | VOLATILE FATTY-ACIDS | CONTINUOUS-CULTURE | Usage | Hydrogen | Amino acids | Fermentation | Fatty acids | Organic compounds
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13. Full Text A multiprotein supercomplex controlling oncogenic signalling in lymphoma
by Phelan, James D and Young, Ryan M and Webster, Daniel E and Roulland, Sandrine and Wright, George W and Kasbekar, Monica and Shaffer, Arthur L and Ceribelli, Michele and Wang, James Q and Schmitz, Roland and Nakagawa, Masao and Bachy, Emmanuel and Huang, Da Wei and Ji, Yanlong and Chen, Lu and Yang, Yandan and Zhao, Hong and Yu, Xin and Xu, Weihong and Palisoc, Maryknoll M and Valadez, Racquel R and Davies-Hill, Theresa and Wilson, Wyndham H and Chan, Wing C and Jaffe, Elaine S and Gascoyne, Randy D and Campo, Elias and Rosenwald, Andreas and Ott, German and Delabie, Jan and Rimsza, Lisa M and Rodriguez, Fausto J and Estephan, Fayez and Holdhoff, Matthias and Kruhlak, Michael J and Hewitt, Stephen M and Thomas, Craig J and Pittaluga, Stefania and Oellerich, Thomas and Staudt, Louis M
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7718, pp. 387 - 391
B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas, but inhibiting this pathway in diffuse large B cell lymphoma (DLBCL)... 
PATHOGENESIS | SURVIVAL | B-CELL LYMPHOMA | INHIBITION | MULTIDISCIPLINARY SCIENCES | KINASE | GENE-EXPRESSION | IBRUTINIB | TARGETS | REQUIRES | SUBGROUPS | Lymphomas | Genetic aspects | B cells | Health aspects | TOR protein | Protein kinase C | Toxicity | Genomes | B-cell receptor | Kinases | Gene sequencing | Proteins | Signal transduction | Dependence | Toll-like receptors | CRISPR | NF-κB protein | Therapeutic applications | Autoantigens | Gene expression | Lymphoma | Bruton's tyrosine kinase | TLR9 protein | Signaling | Inhibitors | Lymphocytes B | Proteomics | Cell lines | Bcl-10 protein | MyD88 protein | Syk protein | Scientific imaging | Mutation | Mass spectrometry | Cancer | Tumors | B-cell lymphoma | Life Sciences | Immunology
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14. Full Text A phase 2/3 multicenter, randomized, open-label study to compare the efficacy and safety of lenalidomide versus investigator's choice in patients with relapsed or refractory diffuse large B-cell lymphoma
by Czuczman, Myron S and Trněný, Marek and Davies, Andrew and Rule, Simon and Linton, Kim M and Wagner-Johnston, Nina and Gascoyne, Randy D and Slack, Graham W and Brousset, Pierre and Eberhard, David A and Hernandez-Ilizaliturri, Francisco J and Salles, Gilles and Witzig, Thomas E and Zinzani, Pier Luigi and Wright, George W and Staudt, Louis M and Yang, Yandan and Williams, P. Mickey and Lih, Chih-Jian and Russo, Jacqueline and Thakurta, Anjan and Hagner, Patrick and Fustier, Pierre and Song, Dale and Lewis, Ian D
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4127 - 4137
Purpose: Randomized, multicenter, open-label, phase 2/3 trial investigating lenalidomide versus investigator's choice (IC) in relapsed/refractory diffuse large... 
SURVIVAL | THERAPY | RITUXIMAB PLUS CYCLOPHOSPHAMIDE | ONCOLOGY | SUBTYPES | VINCRISTINE | DOXORUBICIN | GENE-EXPRESSION | MUTATIONS | CHEMOTHERAPY | STRATEGIES | Immunohistochemistry | Thrombocytopenia | Cell survival | Gemcitabine | Leukopenia | Anemia | Etoposide | Rituximab | Gene expression | Survival | Patients | Lymphoma | Randomization | Oxaliplatin | Lymphocytes B | Experimental design | Safety engineering | Lymphomas | Cancer | Neutropenia | B-cell lymphoma
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15. Full Text Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma
by Lixin Rui and Amanda C. Drennan and Michele Ceribelli and Fen Zhu and George W. Wright and Da Wei Huang and Wenming Xiao and Yangguang Li and Kreg M. Grindle and Li Lu and Daniel J. Hodson and Arthur L. Shaffer and Hong Zhao and Weihong Xu and Yandan Yang and Louis M. Staudt
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 46, pp. E7260 - E7267
Janus kinases (JAKs) classically signal by activating STAT transcription factors but can also regulate gene expression by epigenetically phosphorylating... 
Epigenetics | Histone modification | Lymphoma | Oncogene | JAK1 | histone modification | SIGNATURES | CHROMATIN | MULTIDISCIPLINARY SCIENCES | lymphoma | STAT3 | TRANSCRIPTION | MECHANISMS | oncogene | CANCER | epigenetics | DISEASE | DEREGULATION | MUTATIONS | NF-KAPPA-B | Biological Sciences | PNAS Plus
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