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Free Radical Biology and Medicine, ISSN 0891-5849, 07/2012, Volume 53, Issue 1, pp. 30 - 43
Epithelial–mesenchymal transition (EMT) plays a pivotal role in the pathogenesis of renal tubulointerstitial fibrosis. We previously demonstrated that... 
Oxidative stress | Epithelial–mesenchymal transition | Mitochondrial dysfunction | Free radicals | Aldosterone | Epithelial-mesenchymal transition | APOPTOSIS | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | P66SHC | MUSCLE | SIRT1 | DAMAGE | BIOGENESIS | DISEASE | ENDOCRINOLOGY & METABOLISM | RESISTANCE | RNA, Small Interfering - genetics | Shc Signaling Adaptor Proteins - metabolism | Epithelial Cells - metabolism | Cadherins - metabolism | Epithelial Cells - drug effects | Humans | Transcriptional Activation | Epithelial-Mesenchymal Transition - drug effects | Heat-Shock Proteins - antagonists & inhibitors | Mitochondrial Proteins - genetics | Membrane Potential, Mitochondrial - drug effects | DNA-Binding Proteins - metabolism | Heat-Shock Proteins - genetics | Shc Signaling Adaptor Proteins - antagonists & inhibitors | DNA, Mitochondrial - genetics | Mitochondrial Proteins - metabolism | Sirtuin 1 | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Phosphorylation - drug effects | Cadherins - genetics | Real-Time Polymerase Chain Reaction | DNA Damage - drug effects | Kidney Tubules, Proximal - cytology | Heat-Shock Proteins - metabolism | RNA, Messenger - genetics | Cells, Cultured | Aldosterone - pharmacology | Epithelial Cells - pathology | Transcription Factors - antagonists & inhibitors | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Transcription Factors - metabolism | Shc Signaling Adaptor Proteins - genetics | Src Homology 2 Domain-Containing, Transforming Protein 1 | Kidney Tubules, Proximal - metabolism | Protein Processing, Post-Translational | Oxidative Stress - drug effects | Kidney Tubules, Proximal - drug effects | Yuan (China) | Corticosteroids | RNA | Genes | Mitochondrial DNA | Genetic transcription | Muscle proteins | Cells | Actin | DNA | Resveratrol | Physiological aspects
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 06/2019, Volume 34, Issue Supplement_1
Journal Article
Journal Article
by Cao, W and Yuan, YG and Liu, X and Li, Q and An, XF and Huang, ZM and Wu, L and Zhang, B and Zhang, AH and Xing, CY
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, ISSN 1931-857X, 07/2019, Volume 317, Issue 1, pp. F107 - F115
Numerous studies have demonstrated that several mechanisms, including oxidative stress, DNA damage. and inflammatory responses, arc closely linked to... 
APOPTOSIS | PHYSIOLOGY | OXIDATIVE DAMAGE | ATTENUATES INFLAMMATION | MECHANISMS | AUTOPHAGY | adenosine kinase | ABT-702 | KIDNEY INJURY | TUBULAR EPITHELIAL-CELLS | UROLOGY & NEPHROLOGY | cisplatin nephrotoxicity | RECEPTORS | EXPRESSION | PODOCYTE
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 11/2015, Volume 37, Issue 4, pp. 1240 - 1256
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 03/2018, Volume 9, p. 176
Journal Article
Kidney International, ISSN 0085-2538, 10/2012, Volume 82, Issue 7, pp. 771 - 789
Glomerular podocytes are highly specialized epithelial cells whose injury in glomerular diseases causes proteinuria. Since mitochondrial dysfunction is an... 
mitochondrial dysfunction | podocytes | SIRT1 | aldosterone | PGC-1a | OXIDATIVE STRESS | PGC-1 alpha | INDUCED APOPTOSIS | PGC-1-ALPHA | TRANSCRIPTIONAL COACTIVATOR | CELL APOPTOSIS | METABOLIC REGULATOR | UROLOGY & NEPHROLOGY | RAT PODOCYTES | FOCAL SEGMENTAL GLOMERULOSCLEROSIS | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Apoptosis - drug effects | Receptors, Mineralocorticoid - metabolism | Podocytes - virology | Respiratory Syncytial Virus Infections - metabolism | Stilbenes - pharmacology | Aldosterone | Sirtuin 1 - genetics | Kidney Diseases - genetics | Receptors, Mineralocorticoid - drug effects | Transfection | RNA Interference | Time Factors | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Kidney Diseases - chemically induced | Mineralocorticoid Receptor Antagonists - pharmacology | Trans-Activators - genetics | Respiratory Syncytial Virus Infections - virology | Genes, Reporter | Cytoprotection | Disease Models, Animal | Kidney Diseases - metabolism | Cell Line | Promoter Regions, Genetic | Podocytes - metabolism | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Mice, Inbred C57BL | Gene Expression Regulation | Respiratory Syncytial Virus Infections - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Podocytes - pathology | Animals | Podocytes - drug effects | Mitochondria - virology | Trans-Activators - metabolism | Mice | Transcription Factors | Enzyme Activation | Respiratory Syncytial Viruses - pathogenicity
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2018, Volume 315, Issue 3, pp. F469 - F478
Journal Article
by Li, Q and Zhang, AH and Xing, CY and Yuan, YG
HISTOLOGY AND HISTOPATHOLOGY, ISSN 0213-3911, 08/2019, Volume 34, Issue 8, pp. 835 - 842
Chronic kidney disease (CKD) is recognized as a worldwide health problem. Progression of CKD may lead to many serious complications, which are associated with... 
Chronic kidney disease | KAPPA-B | AUTOPHAGY | PATHOLOGY | AAA PROTEASES | CELL BIOLOGY | HYPEROSIDE | PINK1/PARKIN-MEDIATED MITOPHAGY | Treatment | DNA COPY NUMBER | PROTEIN-QUALITY CONTROL | ACID 5 MA-5 | Mitochondrial homeostasis | TRANSCRIPTION FACTOR | UP-REGULATION
Journal Article
American journal of physiology. Renal physiology, ISSN 0363-6127, 12/2018, Volume 315, Issue 6, pp. F1542 - F1549
Acupuncture with low-frequency electrical stimulation (Acu/LFES) can prevent muscle atrophy by increasing muscle protein anabolism in mouse models of chronic... 
microRNA | Acu/LFES | angiotensinogen | exosome | renal blood flow | PHYSIOLOGY | MECHANISMS | MICRORNAS | RESPONSES | HEMODIALYSIS-PATIENTS | UROLOGY & NEPHROLOGY | DYSFUNCTION | ACUPOINT | KIDNEY
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 02/2011, Volume 300, Issue 2, pp. F393 - F402
Yuan Y, Zhang A, Huang S, Ding G, Chen R. A PPAR gamma agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR... 
Glomerular disease | Peroxisome proliferator-activated receptor-γ | OXIDATIVE STRESS | PHYSIOLOGY | CYCLIN D1 | MAP KINASE | glomerular disease | ACTIVATED RECEPTORS | CANCER | MITOGEN | peroxisome proliferator-activated receptor-gamma | GROWTH | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | THERAPEUTIC TARGETS | KIDNEY
Journal Article