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Nature Medicine, ISSN 1078-8956, 01/2018, Volume 24, Issue 1, pp. 50 - 61
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 45, pp. 16082 - 16087
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 11/2014, Volume 346, Issue 6212, pp. 1000 - 1003
Nucleoside reverse transcriptase inhibitors (NRTIs) are mainstay therapeutics for HIV that block retrovirus replication. Alu (an endogenous retroelement that... 
P2X7 RECEPTOR | PATHOGENESIS | INTERLEUKIN-18 | P2X RECEPTOR | INFLAMMASOME ACTIVATION | MULTIDISCIPLINARY SCIENCES | MACULAR DEGENERATION | NLRP3 INFLAMMASOME | ATP RELEASE | VERSUS-HOST-DISEASE | CASPASE-1 ACTIVATION | Retinal Pigment Epithelium - metabolism | Apoptosis - drug effects | NLR Family, Pyrin Domain-Containing 3 Protein | Reverse Transcriptase Inhibitors - pharmacology | Caspase 1 - metabolism | Geographic Atrophy - drug therapy | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Hepatitis - drug therapy | Animals | Carrier Proteins - metabolism | Choroidal Neovascularization - drug therapy | Graft vs Host Disease - drug therapy | Inflammasomes - drug effects | Liver - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Retinal Pigment Epithelium - physiology | Receptors, Purinergic P2X7 - metabolism | Mice | Reverse Transcriptase Inhibitors - therapeutic use | Alu Elements | Disease Models, Animal | Retinal Pigment Epithelium - drug effects | Prevention | Genetic research | Genetic aspects | Genetic transcription | Research | HIV (Viruses) | Virus research | Macular degeneration | Inhibitor drugs | Drug therapy | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus | Atrophy | Drugs | Inhibitors | Ribonucleic acids | Blocking | Nucleosides | Activation | Grafting
Journal Article
Nature medicine, ISSN 1078-8956, 1/2018, Volume 24, Issue 1, pp. 50 - 61
Geographic atrophy is a blinding form of age-related macular degeneration characterized by death of the retinal pigmented epithelium (RPE). In this disease,... 
Journal Article
Investigative Opthalmology & Visual Science, ISSN 1552-5783, 11/2013, Volume 54, Issue 12, p. 7395
Journal Article
Signal transduction and targeted therapy, ISSN 2059-3635, 03/2016, Volume 1, Issue 1, p. 15002
Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is... 
TARGET | CELLS | INHIBITION | FC-GAMMA RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | TISSUE | IMMUNOGLOBULIN | IVIG | CELL BIOLOGY
Journal Article
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