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Transactions of Japanese Society for Medical and Biological Engineering, ISSN 1347-443X, 2013, Volume 51, Issue Supplement, pp. M-156 - M-156
Journal Article
Cancer, ISSN 0008-543X, 05/2017, Volume 123, Issue 10, pp. 1731 - 1740
Lung adenocarcinoma in patients aged 40 years or younger has a distinctly unique prevalence of oncogenic genetic alterations. Comprehensive screening for... 
ALK | RET | young age | anaplastic lymphoma kinase | lung adenocarcinoma | ROS proto‐oncogene 1 receptor tyrosine kinase | driver oncogene | human epidermal growth factor receptor 2 | HER2 | ROS1 | Ret proto‐oncogene | human epidermal growth factor receptor 2 (HER2) | ROS proto-oncogene 1 receptor tyrosine kinase (ROS1) | anaplastic lymphoma kinase (ALK) | Ret proto-oncogene (RET) | GEFITINIB | REARRANGEMENTS | EGFR | KINASE MUTATIONS | BREAST-CANCER | WOMEN | ONCOLOGY | COLORECTAL-CANCER | FUSIONS | CLINICOPATHOLOGICAL FEATURES | Translocation, Genetic | Adenocarcinoma - pathology | Prognosis | Adenocarcinoma of Lung | Age Factors | Receptor, ErbB-2 - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Protein-Tyrosine Kinases - genetics | Anaplastic Lymphoma Kinase | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Retrospective Studies | Lung Neoplasms - genetics | Gene Fusion | Proto-Oncogene Proteins - genetics | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | Lung Neoplasms - epidemiology | Receptor Protein-Tyrosine Kinases - genetics | Smoking - epidemiology | Aged | Mutation | Adenocarcinoma - epidemiology | Neoplasm Staging | Proto-Oncogene Proteins c-ret - genetics | Young adults | Gene mutations | Lung cancer | Genetic aspects | Research | Diagnosis | Health aspects | Adenocarcinoma | Reactive oxygen species | Homology | Kinases | K-Ras protein | Biological effects | Alterations | Ret protein | Epidermal growth factor | Protein-tyrosine kinase receptors | Age | Translocation | Tyrosine | Sarcoma | Epidermal growth factor receptors | Patients | ErbB-2 protein | Lymphoma | Screening | Medical prognosis | Men | Health risk assessment | Smoking | Cancer
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e214 - e214
OBJECTIVES:Klinefelterʼs syndrome reveals hypogonadism causing increased risks of obesity and glucose intolerance. Although aldosterone excess also associates... 
Case studies | Klinefelter's syndrome | Complications and side effects | Development and progression | Care and treatment | Hyperaldosteronism
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e175 - e175
OBJECTIVES:Time burden is often the primary reason for discontinuing antihypertensive treatment. Telemedicine, now possible in Japan, may help patients adhere... 
Hypertension | Usage | Care and treatment | Safety and security measures | Telemedicine | Sphygmomanometer
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e234 - e234
OBJECTIVES:Primary aldosteronism is sometimes complicated with hyperparathyroidism, which can be classified into secondary hyperparathyroidism due to increased... 
Case studies | Complications and side effects | Development and progression | Care and treatment | Hyperaldosteronism | Hyperparathyroidism
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e233 - e233
OBJECTIVES:Gender difference of blood pressure (BP) becomes smaller later in life. The prescription rate of antihypertensive drug classes and therapeutic... 
Hypertension | Aged patients | Care and treatment | Diagnosis
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e45 - e45
OBJECTIVES:Elevated soluble (pro)renin receptor [s(P)RR] concentration in maternal blood is associated with gestational hypertension and preeclampsia.... 
Trophoblast | Research | Hypertension in pregnancy | Renin-angiotensin system | Risk factors
Journal Article
HYPERTENSION RESEARCH, ISSN 0916-9636, 06/2018, Volume 41, Issue 6, pp. 435 - 443
The (pro)renin receptor is important in the regulation of the tissue renin-angiotensin-aldosterone system. The benefits and safety of single-aliskiren... 
ALBUMINURIA | ARTERIAL STIFFNESS | HEART-FAILURE | ANKLE VASCULAR INDEX | PRO RENIN RECEPTOR | PERIPHERAL VASCULAR DISEASE | EXPRESSION | STAGE RENAL-DISEASE | BLOOD-PRESSURE | PREGNANCY | PREDICTION | Hypertension | Blood pressure | Kidney diseases | ACE inhibitors
Journal Article
Journal of Diabetes and Its Complications, ISSN 1056-8727, 2014, Volume 28, Issue 5, pp. 604 - 611
Abstract Aims Kidney cells in patients with diabetic nephropathy are reported to be senescent. However, the mechanisms that regulate cellular senescence in the... 
Endocrinology & Metabolism | Diabetic nephropathy | Sodium glucose cotransporter 2 | Insulin | p21 | Cellular senescence | Proximal tubular cells | LLC-PK1 CELLS | P21(WAF1/CIP1) | ATHEROSCLEROSIS | GLOMERULAR HYPERTROPHY | GROWTH | ENDOCRINOLOGY & METABOLISM | ALDOSTERONE | MICE | KIDNEY | EXPRESSION | Streptozocin | Diabetes Mellitus, Experimental - genetics | Diabetes Mellitus, Type 1 - metabolism | Hyperglycemia - complications | Male | Diabetes Mellitus, Type 1 - complications | Hyperglycemia - genetics | Diabetic Nephropathies - physiopathology | Cyclin-Dependent Kinase Inhibitor p21 - physiology | Diabetes Mellitus, Experimental - complications | Diabetes Mellitus, Experimental - metabolism | Hyperglycemia - physiopathology | Diabetes Mellitus, Experimental - physiopathology | Kidney Tubules, Proximal - physiopathology | Cellular Senescence - genetics | Diabetes Mellitus, Type 1 - physiopathology | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Cells, Cultured | Diabetes Mellitus, Type 1 - genetics | Diabetic Nephropathies - genetics | Disease Progression | Sodium-Glucose Transporter 2 - physiology | Diabetic Nephropathies - complications | Animals | Kidney Tubules, Proximal - metabolism | Signal Transduction - physiology | Mice | Evaluation | Glucose metabolism | Hyperglycemia | Diabetic nephropathies | Glucose | Dextrose
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e105835 - e105835
Gamma-aminobutyric acid (GABA) is an important neurotransmitter, but recent reports have revealed the expression of GABAergic components in peripheral,... 
SYSTEM | CELLS | EPITHELIUM | CLONING | MULTIDISCIPLINARY SCIENCES | DOPAMINE | SUBUNITS | GAMMA-AMINOBUTYRIC-ACID | IDENTIFICATION | BLOOD-PRESSURE | BRAIN | Immunohistochemistry | Protein Subunits | Kidney Cortex - metabolism | Humans | Rats, Inbred WKY | Male | RNA, Messenger - metabolism | 4-Aminobutyrate Transaminase - metabolism | GABA Plasma Membrane Transport Proteins - metabolism | Adult | Female | Hypertension - genetics | Rats, Inbred SHR | Gene Expression | RNA, Messenger - genetics | Rats | Glutamate Decarboxylase - genetics | 4-Aminobutyrate Transaminase - genetics | Hypertension - metabolism | GABA Plasma Membrane Transport Proteins - genetics | Animals | gamma-Aminobutyric Acid - biosynthesis | Receptors, GABA-A - classification | Receptors, GABA-A - genetics | Glutamate Decarboxylase - metabolism | Receptors, GABA-A - metabolism | GABA | Enzymes | Brain | Glutamate | Nephrology | γ-Aminobutyric acid A receptors | Syngeneic grafts | Paracrine signalling | γ-Aminobutyric acid C receptors | Neurogenesis | Receptors | γ-Aminobutyric acid | Rodents | Animal tissues | Blood pressure | Autocrine signalling | Hypertension | γ-Aminobutyric acid B receptors | Medical research | Dopamine | Kidneys | 4-Aminobutyrate transaminase | Cloning | Tubules | Pharmacology | Glutamate decarboxylase | Metabolism | Polymerase chain reaction | Medicine | Acids | Sodium | Diabetes | Renal cortex | Transporter | Endocrinology | γ-Aminobutyric acid receptors | Index Medicus
Journal Article