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by Martin, Miguel and Holmes, Frankie A and Ejlertsen, Bent and Delaloge, Suzette and Moy, Beverly and Iwata, Hiroji and von Minckwitz, Gunter and Chia, Stephen K L and Mansi, Janine and Barrios, Carlos H and Gnant, Michael and Tomašević, Zorica and Denduluri, Neelima and Šeparović, Robert and Gokmen, Erhan and Bashford, Anna and Ruiz Borrego, Manuel and Kim, Sung-Bae and Kim, Seung Jin and Jakobsen, Erik Hugger and Ciceniene, Audrone and Inoue, Kenichi and Overkamp, Friedrich and Heijns, Joan B and Armstrong, Anne C and Link, John S and Joy, Anil Abraham and Bryce, Richard and Wong, Alvin and Moran, Susan and Yao, Bin and Xu, Feng and Xu, Binghe and Auerbach, Alan and Buyse, Marc and Chan, Arlene and Harvey, Vernon and Tomek, Rudolf and Robert, Nicholas J and Gore, Ira and Smith, John W and Smith, Julie C and Masuda, Norikazu and Di Sean Kendall, S and Harker, William Graydon and Petrakova, Katarina and Guerrero Zotano, Angel and Simon, Amparo Ruiz and Konstantinovic, Zora Neskovic and Iannotti, Nicholas O and Tassone, Pierfrancesco and Rodriguez, Gladys I and Jáñez Martinez, Noelia and Crespo Massieu, Carmen and Smickoska, Snezana and Somali, Isil and Yilmaz, Ugur and Alonso, Mirta Garcia and Rosales, Adolfo Murias and Cold, Soeren and Knoop, Ann Soegaard and Patt, Debra and Hellerstedt, Beth A and Morales Murillo, Serafin and Mayer, Ingrid A and Means-Powell, Julie Ann and Hui, Rina and Senecal, Francis M and De Boer, Richard Hendry and Shen, Zhenzhou and Luczak, Adam Andrzej and Chui, Joanna W.Y and Chui, Stephen and Tsang, Janice Wing-hang and Lang, Istvan and Rai, Yoshiaki and Hozumi, Yasuo and Ten Tije, Albert J and Bhandari, Manish and Osborne, Cynthia R.C and Ohtani, Shoichiro and Higaki, Kenji and Watanabe, Junichiro and Watanabe, Kenichi and Taguchi, Tetsuya and Taguchi, Kazunori and Takahashi, Masato and Filipovic, Sladjana and Hansen, Vincent L and Rao, Vijayarama Phooshkooru and Gupta, Manish and Petrov, Petar and Coudert, Bruno and Vojnovic, Zeljko and Polya, Zsofia and Miyaki, Toshiko and Yamamoto, Naohito and Brincat, Stephen and Lesniewski-Kmak, Krzysztof and Chmielowska, Ewa and ... and ExteNET Study Grp and ExteNET Study Group
The Lancet Oncology, ISSN 1470-2045, 12/2017, Volume 18, Issue 12, pp. 1688 - 1700
Journal Article
BMC Cancer, ISSN 1471-2407, 06/2018, Volume 18, Issue 1
It is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and chemoresistance in order to identify prognostic... 
Chemotherapy | Genes | Development and progression | Genetic aspects | Hepatoma | Research | Gene expression | Health aspects | Cancer
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 6, pp. 619 - 629
Journal Article
ANZ Journal of Surgery, ISSN 1445-1433, 04/2016, Volume 86, Issue 4, pp. 289 - 293
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2017, Volume 23, Issue 10, pp. 2405 - 2413
Purpose: This phase I/II single-arm study evaluated the safety, pharmacokinetics, pharmacodynamics, and activity of foretinib, an oral multikinase inhibitor of... 
MANAGEMENT | BIOMARKER | ONCOLOGY | PATHWAY | TIVANTINIB | HEPATOCYTE GROWTH-FACTOR | C-MET | SORAFENIB | INHIBITOR | EXPRESSION | CANCER-THERAPY | Humans | Middle Aged | Male | Anilides - pharmacokinetics | Quinolines - administration & dosage | Liver Neoplasms - blood | Quinolines - pharmacokinetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Carcinoma, Hepatocellular - drug therapy | Interleukin-6 - blood | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Liver Neoplasms - pathology | Carcinoma, Hepatocellular - blood | Interleukin-8 - blood | Receptor, TIE-2 - antagonists & inhibitors | Proto-Oncogene Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Liver Neoplasms - drug therapy | Biomarkers, Pharmacological - blood | Maximum Tolerated Dose | Anilides - administration & dosage | Carcinoma, Hepatocellular - pathology | Aged | Protein-Tyrosine Kinases - antagonists & inhibitors | Reactive oxygen species | Hepatocellular carcinoma | Axl protein | Anticancer properties | Interleukin 6 | Liver cancer | Safety engineering | Design standards | Bioindicators | Safety | Interleukin 8 | Hypertension | Appetite | Pharmacodynamics | Pharmacology | Survival | Patients | Fever | Ron protein | Experimental design | Biomarkers | Antitumor activity | Plasma levels | Pharmacokinetics | Ascites | Cancer | Index Medicus | VEGFR2 | clinical trial | KDR | systemic cancer therapy | small molecule multikinase inhibitor | vascular endothelial growth factor receptor-2 | foretinib | MET | hepatocellular carcinoma | hepatocyte growth factor receptor
Journal Article
Journal of the American Statistical Association, ISSN 0162-1459, 07/2015, Volume 110, Issue 511, pp. 1175 - 1186
The threshold autoregressive (TAR) model is a class of nonlinear time series models that have been widely used in many areas. Due to its nonlinear nature, one... 
Change-point detection | Piecewise modeling | Multiple-threshold | Genetic algorithms | Minimum description length principle | Nonstationary time series | CONSISTENCY | MINIMUM DESCRIPTION LENGTH | TIME-SERIES MODELS | STATISTICS & PROBABILITY | PRINCIPLE | SELECTION | Estimating techniques | Regression analysis | Simulation | Experiments | Time series
Journal Article
American Heart Journal, ISSN 0002-8703, 2010, Volume 160, Issue 5, pp. 785 - 794.e10
Background Lowering low-density lipoprotein (LDL) cholesterol with statin therapy has been shown to reduce the incidence of atherosclerotic events in many... 
Cardiovascular | UNITED-KINGDOM HEART | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | REQUIRING PROLONGED OBSERVATION | EFFICACY | CARDIOVASCULAR OUTCOMES | SAFETY | CLINICAL-TRIALS | SIMVASTATIN | EZETIMIBE | STATINS | Simvastatin - therapeutic use | Follow-Up Studies | Humans | Middle Aged | Ezetimibe | Male | Incidence | Dose-Response Relationship, Drug | Atherosclerosis - etiology | Adult | Cholesterol, LDL - blood | Female | Retrospective Studies | Drug Therapy, Combination | Double-Blind Method | Simvastatin - administration & dosage | Cholesterol, LDL - drug effects | Treatment Outcome | Atherosclerosis - blood | Kidney Failure, Chronic - therapy | Anticholesteremic Agents - therapeutic use | Azetidines - administration & dosage | Azetidines - therapeutic use | Kidney Failure, Chronic - blood | Anticholesteremic Agents - administration & dosage | Kidney Failure, Chronic - complications | Aged | Atherosclerosis - prevention & control | Renal Dialysis | Medicine, Experimental | Medical research | Chronic kidney failure | Analysis | Low density lipoproteins | Cholesterol | Lipids | Heart attacks | Drug therapy | Low density lipoprotein | Index Medicus | Abridged Index Medicus | Clinical Medicine | Urologi och njurmedicin | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Urology and Nephrology
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2010, Volume 6, Issue 6, pp. 603 - 615
Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for tumor growth in colorectal cancer. However,... 
STEMCELL | CELLCYCLE | BREAST-CANCER | INITIATING CELLS | DIPEPTIDYL-PEPTIDASE-IV | CARCINOMA CELLS | EXTRACELLULAR-MATRIX | ACUTE MYELOID-LEUKEMIA | E-CADHERIN | IDENTIFICATION | TUMOR-GROWTH | HUMAN PANCREATIC-CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplasm Transplantation | RNA, Small Interfering - genetics | Prognosis | Follow-Up Studies | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Apoptosis - genetics | Gene Expression Profiling | Colorectal Neoplasms - diagnosis | Organoplatinum Compounds - pharmacology | Neoplastic Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Tumor Burden - genetics | Tumor Cells, Cultured | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Carcinoma - secondary | Carcinoma - drug therapy | Liver Neoplasms - genetics | Dipeptidyl Peptidase 4 - biosynthesis | Liver Neoplasms - drug therapy | Carcinoma - diagnosis | Dipeptidyl Peptidase 4 - genetics | Mice, SCID | Carcinoma - physiopathology | Disease Progression | Colorectal Neoplasms - physiopathology | Drug Resistance, Neoplasm - genetics | Animals | Liver Neoplasms - diagnosis | Tumor Burden - drug effects | Liver Neoplasms - metabolism | Carcinoma - genetics | Biomarkers, Tumor - genetics | Fluorouracil - pharmacology | Mice | Carcinoma - metabolism | Colorectal Neoplasms - pathology | Neoplasm Invasiveness - genetics | Cell Migration Assays | Biomarkers, Tumor - biosynthesis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, pp. e94453 - e94453
Background and aim: Spontaneous rupture of hepatocellular carcinoma (HCC) carries a high mortality. The use of radiofrequency ablation (RFA) in recent years... 
SINGLE-CENTER-EXPERIENCE | LIVER-TRANSPLANTATION | CHEMOEMBOLIZATION | EMBOLIZATION |