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The Journal of Pathology, ISSN 0022-3417, 01/2014, Volume 232, Issue 2, pp. 210 - 218
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 3602 - 3602
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2009, Volume 361, Issue 12, pp. 1164 - 1172
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2012, Volume 44, Issue 10, pp. 1111 - 1116
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 572 - 574
The Hedgehog (Hh) signaling pathway is inappropriately activated in certain human cancers, including medulloblastoma, an aggressive brain tumor. GDC-0449, a... 
Receptors | Relapse | Basal cell carcinoma | Medulloblastoma | Amino acids | Biopsies | Reports | Genetic mutation | Tumors | Resistance mechanisms | Cancer | PROTEIN-COUPLED RECEPTORS | CYCLOPAMINE | CANCER | MULTIDISCIPLINARY SCIENCES | Anilides - therapeutic use | Receptors, G-Protein-Coupled - metabolism | Humans | Brain Neoplasms - pathology | Hedgehog Proteins - metabolism | Molecular Sequence Data | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Mutation, Missense | Antineoplastic Agents - metabolism | Neoplasm Metastasis | Hedgehog Proteins - genetics | Medulloblastoma - pathology | Smoothened Receptor | Veratrum Alkaloids - pharmacology | Antineoplastic Agents - pharmacology | Patched Receptors | Medulloblastoma - genetics | Mutant Proteins - antagonists & inhibitors | Pyridines - therapeutic use | Amino Acid Sequence | Signal Transduction | Anilides - metabolism | Brain Neoplasms - genetics | Receptors, Cell Surface - metabolism | Mutant Proteins - metabolism | Hedgehog Proteins - antagonists & inhibitors | Brain Neoplasms - drug therapy | Cinnamates - pharmacology | Animals | Pyridines - metabolism | Mutant Proteins - chemistry | Anilides - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Cell Line, Tumor | Protein Conformation | Mice | Pyridines - pharmacology | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Receptors, G-Protein-Coupled - chemistry | Amino Acid Substitution | Receptors, Cell Surface - genetics | Gene mutations | Development and progression | Genetic aspects | Diagnosis | Drug resistance | Identification and classification | Signal transduction | Genotype & phenotype | Inhibitor drugs | Cellular biology | Brain cancer | Mutation
Journal Article
Nature Biotechnology, ISSN 1087-0156, 01/2015, Volume 33, Issue 3, pp. 306 - 312
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2012, Volume 366, Issue 23, pp. 2180 - 2188
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2012, Volume 366, Issue 23, pp. 2171 - 2179
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2005, Volume 11, Issue 24, pp. 8686 - 8698
Significant improvements in the outcome of non–small cell lung carcinoma (NSCLC) have been reported in patients treated with the epidermal growth factor... 
biomarker | E-cadherin | EMT | erlotinib | EGFR | TRANSITION | GROWTH-FACTOR RECEPTOR | CELLS | GEFITINIB | ONCOLOGY | ADENOCARCINOMAS | TYROSINE KINASE INHIBITOR | EGFR MUTATIONS | E-CADHERIN | TISSUE MICROARRAY | EXPRESSION | Erlotinib Hydrochloride | Immunohistochemistry | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Cadherins - metabolism | Oligonucleotide Array Sequence Analysis | Vimentin - metabolism | Humans | Epithelium - chemistry | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Carcinoma, Non-Small-Cell Lung - diagnosis | Vimentin - genetics | Biomarkers, Tumor - metabolism | Antineoplastic Agents - pharmacology | Cadherins - genetics | Genes, Neoplasm - genetics | Epithelium - pathology | Pharmacogenetics | Epithelium - metabolism | Biomarkers, Tumor - analysis | Mesoderm - chemistry | Cadherins - analysis | Treatment Outcome | Vimentin - analysis | Phenotype | Gene Amplification | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Cell Proliferation - drug effects | Mesoderm - metabolism | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Lung Neoplasms - diagnosis | Quinazolines - pharmacology | Mesoderm - pathology
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2013, Volume 19, Issue 1, pp. 258 - 267
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2015, Volume 27, Issue 3, pp. 327 - 341
Journal Article