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Nature Biotechnology, ISSN 1087-0156, 02/2011, Volume 29, Issue 2, pp. 158 - 165
Almost all infectious diseases are initiated at mucosal surfaces, yet intramuscular or subcutaneous vaccination usually provides only minimal protection at... 
CPG OLIGODEOXYNUCLEOTIDES | IMMUNIZATION | RESPONSES | PROTECTIVE IMMUNITY | SIMPLEX-VIRUS TYPE-2 | EPITHELIAL-CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HERPES | IGG TRANSPORT | GENITAL-TRACT | ADJUVANT | Recombinant Fusion Proteins - immunology | Receptors, Fc - metabolism | Vaccines - pharmacokinetics | Vagina - immunology | Administration, Mucosal | Recombinant Fusion Proteins - metabolism | Histocompatibility Antigens Class I - metabolism | Flow Cytometry | Immunoglobulin G - immunology | Viral Envelope Proteins - metabolism | Female | Molecular Targeted Therapy - methods | Cell Line | Viral Envelope Proteins - genetics | Cytokines - metabolism | Histocompatibility Antigens Class I - immunology | Kaplan-Meier Estimate | Vaccines - immunology | Histocompatibility Antigens Class I - genetics | Mice, Knockout | Mucous Membrane - metabolism | Animals | Immunoglobulin G - genetics | Receptors, Fc - immunology | Mucous Membrane - immunology | Recombinant Fusion Proteins - genetics | Receptors, Fc - genetics | Viral Envelope Proteins - immunology | Mice | Vaccines - administration & dosage | Immunoglobulin G - metabolism | Fc receptors | Vaccination | Immunoglobulin G | Physiological aspects | Research | Health aspects | Mucous membrane | Pharmaceutical biotechnology | Glycoproteins | Infectious diseases | Vaccines | Immune system
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2012, Volume 109, Issue 25, pp. 9965 - 9970
Journal Article
文史精华, ISSN 1005-4154, 2016, Issue 14, pp. 4 - 7
“马客”“麦喀士”初来乍到 19世纪末,东方睡狮的漫漫长夜即将渐渐过去。这时.一个德国人的名字及其学说开始传入中国。 
德国人 | 中国 | 19世纪末
Journal Article
Immunity, ISSN 1074-7613, 02/2019, Volume 50, Issue 2, pp. 403 - 417.e4
The tolerogenic microenvironment of the liver is associated with impaired hepatic T cell function. Here, we examined the contribution of liver-resident... 
PD-L1 | antiviral responses | liver-resident NK cells | hepatic T cells | conventional NK cells | hepatic T cells | TISSUE-RESIDENT | IMMUNITY | RESPONSES | NATURAL-KILLER-CELLS | IFN-GAMMA | RECEPTOR | INFECTION | INNATE LYMPHOID-CELLS | ACCUMULATION | IMMUNOLOGY | ANTIGEN | Liver - virology | Lymphocytic choriomeningitis virus - immunology | Transcriptome - immunology | Hepatocytes - metabolism | Lymphocytic Choriomeningitis - immunology | T-Lymphocytes - virology | Lymphocytic Choriomeningitis - metabolism | Signal Transduction - immunology | Liver - immunology | T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Lymphocytic choriomeningitis virus - physiology | Lymphocytic Choriomeningitis - virology | Liver - metabolism | Mice, Inbred C57BL | Programmed Cell Death 1 Receptor - metabolism | Mice, Transgenic | Transcriptome - genetics | Hepatocytes - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Mice, Knockout | B7-H1 Antigen - metabolism | Animals | Hepatocytes - virology | T-Lymphocytes - immunology | Killer Cells, Natural - metabolism | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Virus diseases | Antiviral agents | Medical colleges | Killer cells | Adenoviruses | Liver | Chronic diseases | T cells | Health aspects | Cells | Ontology | PD-1 protein | Immune clearance | Chronic infection | Viruses | Infections | Lymphocytes T | Immunity | Hepatitis | Cell growth | Lymphocytes | Antiviral activity | Tumor necrosis factor-TNF | Inhibition | Natural killer cells | Cytokines | Gene expression | Immunological tolerance | Variance analysis | Hepatocytes | PD-L1 protein | Ligands | Mice | Viral infections
Journal Article
Immunity, ISSN 1074-7613, 09/2017, Volume 47, Issue 3, pp. 538 - 551.e5
Follicular regulatory T Tfr cells differentiate from conventional regulatory T Treg cells and suppress excessive germinal center GC responses by acting on both... 
follicular helper T cells | acute viral infection | protein immunization | regulatory T cells | mTORC1 | follicular regulatory T cells | regulatory T cells | follicular regulatory T cells | follicular helper T cells | ACTIVATION | HELPER | METABOLISM | MEMORY | TCF-1 | GERMINAL CENTER REACTIONS | IMMUNE-RESPONSES | AKT-MTOR | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | T-Lymphocytes, Regulatory - metabolism | Immunization | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Immunomodulation | Immunophenotyping | Mice, Transgenic | Multiprotein Complexes - genetics | Gene Expression Profiling | Hepatocyte Nuclear Factor 1-alpha - metabolism | Mechanistic Target of Rapamycin Complex 1 | T-Lymphocytes, Regulatory - immunology | Cell Differentiation - immunology | Multiprotein Complexes - metabolism | Animals | TOR Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-bcl-6 - metabolism | T-Lymphocytes, Regulatory - cytology | Biomarkers | Mice | STAT3 Transcription Factor - metabolism | Cluster Analysis | Virus diseases | B cells | T cells | Cell differentiation | Protein kinases | Medical colleges | TOR protein | Phosphorylation | Transcription factors | Differentiation (biology) | Homeostasis | Lymphocytes T | Infections | Kinases | Lymphocytes | Rodents | Hepatocyte nuclear factor 1 | Cues | Threonine | Immunoregulation | Stat3 protein | Cell division | T cell receptors | Metabolism | Lymphocytes B | Protein kinase | Bcl protein | Protein-serine/threonine kinase | Bcl-6 protein
Journal Article
Nature Communications, ISSN 2041-1723, 05/2017, Volume 8, Issue 1, p. 15402
The connection between innate and adaptive immunity is best exemplified by antigen presentation. Although antigen-presenting cells (APCs) are required for... 
RESPONSES | TRIGGER | MULTIDISCIPLINARY SCIENCES | MECHANISMS | IL-1-BETA | DEATH | DIFFERENTIATION | PATTERN-RECOGNITION RECEPTORS | VERSUS-HOST-DISEASE | BINDING
Journal Article