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Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1664 - 1664
Journal Article
Neuropharmacology, ISSN 0028-3908, 07/2019, p. 107678
There is unmet need to design an analgesic with fewer side effects for severe pain management. Although traditional opioids are the most effective painkillers,... 
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 16, pp. 7087 - 7102
Journal Article
Scientific Reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, pp. 7972 - 18
P-glycoprotein (P-gp) is a drug transporter that effluxes chemotherapeutic drugs and is implicated in the development of resistance of cancer cells to... 
BREAST-CANCER | DESIGN | MEDIATED MULTIDRUG-RESISTANCE | SOLID TUMORS | TRANSPORTERS | MODULATORS | MULTIDISCIPLINARY SCIENCES | INHIBITORS | BINDING POCKET | CELL-LINES | PHASE-I | Rhodamine | Glycoproteins | Phosphatidylinositol 4,5-diphosphate | Cervix | Drug resistance | Drug development | Vincristine | Molecular weight | Chemotherapy | Colon cancer | Paclitaxel | Colchicine | Colon | P-Glycoprotein | Cancer
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 9/2007, Volume 115, Issue 9, pp. 1339 - 1343
Journal Article
Environmental Science and Technology, ISSN 0013-936X, 08/2008, Volume 42, Issue 16, pp. 6264 - 6270
We conducted pharmacokinetic and toxicology studies on Quantum Dot 705 (QD705) in male ICR mice for up to 6 months after a single intravenous dose. Time-course... 
ENVIRONMENTAL SCIENCES | ENGINEERING, ENVIRONMENTAL | LIVE CELLS | DNA | IN-VIVO | QUANTUM DOTS | Tissue Distribution | Animals | Biological Transport | Kidney - pathology | Quantum Dots | Kidney Diseases - chemically induced | Male | Mice | Time | Mitochondria - drug effects | Nanoparticles - toxicity
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2019, Volume 852, pp. 265 - 273
Oxycodone, a widely prescribed and very potent oral opioid analgesic agent, is highly addictive and has many side effects, including troublesome constipation.... 
Tolerance | Naltrindole | Conditioned place preference | Delta-opioid receptor | Oxycodone | Dependence | UNITED-STATES | DOPAMINE RELEASE | ANALGESIC ABUSE | MORPHINE | MU | NUCLEUS-ACCUMBENS | GASTROINTESTINAL TRANSIT | PAIN | RELAPSE VULNERABILITY | PHARMACOLOGY & PHARMACY | Drug abuse | Liability (Law) | Constipation | Opioids
Journal Article
Future Medicinal Chemistry, ISSN 1756-8919, 2019, Volume 11, Issue 9, pp. 959 - 974
Aim: Bladder cancer is a highly recurrent urologic malignancy with limited treatment approaches. Previously, we reported compound 11 is a FGFR3 inhibitor with... 
CK1δ | apoptosis | cancer | MOLECULAR SUBTYPES | SURVIVAL | BLADDER-CANCER | CHEMISTRY, MEDICINAL | PHOSPHORYLATION | CK1-DELTA | FAMILY | KINASE-I EPSILON | INHIBITION | GROWTH | EXPRESSION | CK1 delta
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 16, pp. 7087 - 7102
This paper reports the development of a series of 5-aroylindolyl-substituted hydroxamic acids. N-Hydroxy-4((5-(4-methoxybenzoyl)-1H-indol-1-yl)methyl)benzamide... 
DESIGN | POTENT | CHEMISTRY, MEDICINAL | PROTEIN | SERIES | ACETYLATION | HDAC6 INHIBITOR | DEFICITS | CANCER | AGGREGATION
Journal Article
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2016, Volume 111, pp. 867 - 876
Journal Article
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 6/2018, Volume 16, Issue 25, pp. 4734 - 4734
Correction for '2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition' by Kunal Nepali et al.... 
Proteins | Hsp90 protein | Tubulin | Antitumor agents | Heat shock proteins | Inhibition | Cancer | Heat shock | Anticancer properties
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2019, Volume 167, pp. 245 - 268
A medicinal chemistry program based on the small-molecule HCV NS5A inhibitor daclatasvir has led to the discovery of dimeric phenylthiazole compound , a novel... 
Discovery | NS5A inhibitor | Phenylthiazole | HCV | SAR | Inhibitory activity | PLUS RIBAVIRIN | CHEMISTRY, MEDICINAL | COMBINATION THERAPY | INTERGENOTYPIC RECOMBINANT | OPEN-LABEL | PREVIOUS NULL-RESPONSE | PROTEASE INHIBITOR | PEGINTERFERON ALPHA-2A | NONNUCLEOSIDE INHIBITOR | GENOTYPE 1 INFECTION | TREATMENT-NAIVE PATIENTS | Hepatitis C virus | Gangliosides | Research institutes
Journal Article
The Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2016, Volume 71, Issue 7, p. 1922
  Enterovirus 71 (EV-A71) is an important pathogen that can cause severe neurological symptoms and even death. Our aim was to identify potent anti-EV-A71... 
Proteins | Mutagenesis | Rodents | Viruses | Binding sites
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2016, Volume 71, Issue 7, pp. 1922 - 1932
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 1756 - 1756
Journal Article
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