X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (10) 10
apoptosis (6) 6
humans (6) 6
male (6) 6
oxidative stress (6) 6
proteins (6) 6
animals (5) 5
activation (4) 4
articles (4) 4
ataxia (4) 4
cell biology (4) 4
dna damage (4) 4
female (4) 4
medical research (4) 4
medicine (4) 4
medicine, research & experimental (4) 4
mice (4) 4
mitochondria (4) 4
mutation (4) 4
patients (4) 4
senataxin (4) 4
analysis (3) 3
article (3) 3
biochemistry (3) 3
biology (3) 3
clinical trials (3) 3
cytotoxicity (3) 3
deoxyribonucleic acid--dna (3) 3
dna repair (3) 3
dna-damage (3) 3
expression (3) 3
gene expression (3) 3
genetic aspects (3) 3
genetics (3) 3
inflammation (3) 3
meiosis (3) 3
multidisciplinary sciences (3) 3
neurodegeneration (3) 3
oncology (3) 3
pulmonary fibrosis (3) 3
research (3) 3
research article (3) 3
rna helicases - genetics (3) 3
science (3) 3
transcription (3) 3
transplantation (3) 3
adolescent (2) 2
animal model (2) 2
antineoplastic agents - therapeutic use (2) 2
ataxia-telangiectasia (2) 2
autophagy (2) 2
biology and life sciences (2) 2
bone marrow mesenchymal stem (2) 2
brain (2) 2
cancer (2) 2
cell cycle (2) 2
cell proliferation (2) 2
cell therapy (2) 2
chemotherapy (2) 2
chromosomes (2) 2
defects (2) 2
deoxyribonucleic acid (2) 2
disease (2) 2
disease models, animal (2) 2
dna (2) 2
dna breaks, double-stranded (2) 2
enzymes (2) 2
genes (2) 2
genetic transcription (2) 2
genetics & heredity (2) 2
health aspects (2) 2
homeostasis (2) 2
ionizing radiation (2) 2
kinases (2) 2
lung (2) 2
lung diseases (2) 2
medicine and health sciences (2) 2
middle aged (2) 2
mitochondria - metabolism (2) 2
model organisms (2) 2
molecular cell biology (2) 2
nanomaterials (2) 2
nanoparticles (2) 2
oculomotor apraxia type-2 (2) 2
pathogenesis (2) 2
pathway (2) 2
phosphorylation (2) 2
r-loops (2) 2
research and analysis methods (2) 2
respiratory diseases (2) 2
risk factors (2) 2
rodents (2) 2
silica (2) 2
silica nanoparticles (2) 2
silicosis (2) 2
spinocerebellar ataxias - congenital (2) 2
stem-cells (2) 2
streptococcus infections (2) 2
stromal cells (2) 2
studies (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90219
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 08/2017, Volume 196, Issue 3, pp. 391 - 393
In this context, there is accumulating evidence that oxidative stress is associated with A-T disease, including increased sensitivity to oxidative damage,... 
MICE | MANAGEMENT | RESPIRATORY SYSTEM | ATAXIA-TELANGIECTASIA | CRITICAL CARE MEDICINE | Medical research | Oxidative stress | Lung diseases | Childrens health | Patients | Respiratory system | Children & youth | Streptococcus infections | Microorganisms | Lymphocytes | Respiratory diseases | Ataxia | Deoxyribonucleic acid--DNA | Cancer | Apoptosis
Journal Article
Toxicology Letters, ISSN 0378-4274, 12/2019, Volume 317, pp. 59 - 67
Toluene-diisocyanate (TDI) is mainly used in the manufacturing process of polyurethane foams, and is a potent inducer of occupational asthma characterized by... 
Thymic stromal lymphopoietin (TSLP) | Inflammation | Interleukin-17 (IL-17) | Toluene-diisocyanate (TDI) | Asthma | ACTIVATION | DENDRITIC CELLS | PULMONARY-FUNCTION | REGULATORY T-CELLS | TDI | TOXICOLOGY | ALLERGIC DISEASES | EXPRESSION | OCCUPATIONAL-EXPOSURE | TH2 | Isocyanates | Interleukins | Analysis | Toluene | Immunoglobulin E
Journal Article
EXPERIMENTAL AND THERAPEUTIC MEDICINE, ISSN 1792-0981, 03/2019, Volume 17, Issue 3, pp. 2247 - 2255
Previous studies have demonstrated that bone marrow mesenchymal stem cell (BMSC) transplantation is a promising treatment strategy for pulmonary fibrosis.... 
MEDICINE, RESEARCH & EXPERIMENTAL | bleomycin | treatment | LUNG | pulmonary fibrosis | bone marrow mesenchymal stem cells | systematic review
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2013, Volume 9, Issue 4
  Senataxin, mutated in the human genetic disorder ataxia with oculomotor apraxia type 2 (AOA2), plays an important role in maintaining genome integrity by... 
Proteins | Genetics | DNA repair | Chromosomes | DNA damage
Journal Article
by Zhang, EG and Yang, Y and Chen, SY and Peng, C and Lavin, MF and Yeo, AJ and Li, C and Liu, XS and Guan, YJ and Du, XJ and Du, ZJ and Shao, H
STEM CELL RESEARCH & THERAPY, ISSN 1757-6512, 11/2018, Volume 9, Issue 1
Journal Article
Cell Discovery, ISSN 2056-5968, 09/2015, Volume 1, Issue 1, p. 15025
Senataxin, defective in ataxia oculomotor apraxia type 2, protects the genome by facilitating the resolution of RNA-DNA hybrids (R-loops) and other aspects of... 
chromatin remodeling | DNA damage repair | Senataxin | meiosis | transcription | senataxin | CELL BIOLOGY
Journal Article
Expert Opinion on Orphan Drugs, ISSN 2167-8707, 12/2016, Volume 4, Issue 12, pp. 1263 - 1276
Introduction: Ataxia-Telangiectasia (A-T) is an autosomal recessive multisystem disease affecting the brain, immune system, lungs, liver and also characterised... 
Ataxia-telangiectasia | liver disease | ATM protein | neurodegeneration | lung disease | clinical trials | steroids | oxidative stress | DNA-DAMAGE | LABORATORY FEATURES | PLURIPOTENT STEM-CELLS | PEDIATRIC-PATIENTS | NON-HODGKIN-LYMPHOMA | MITOCHONDRIAL DYSFUNCTION | PHARMACOLOGY & PHARMACY | CHROMOSOMAL BREAKAGE SYNDROMES | NEUROLOGICAL SYMPTOMS | ATM-DEFICIENT MICE
Journal Article
Rare Diseases, ISSN 2167-5511, 01/2013, Volume 1, Issue 1, p. e25230
Ataxia oculomotor apraxia type 2 (AOA2) is a rare autosomal recessive disorder characterized by cerebellar atrophy, peripheral neuropathy, loss of Purkinje... 
senataxin | SETX gene | Ataxia oculomotor apraxia type 2 (AOA2) | neurodegeneration | R-loops | RNA processing | DNA double strand breaks
Journal Article
by Yang, Y and Du, XJ and Wang, Q and Liu, JW and Zhang, EG and Sai, LL and Peng, C and Lavin, MF and Yeo, AJ and Yang, X and Shao, H and Du, ZJ
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, ISSN 1107-3756, 09/2019, Volume 44, Issue 3, pp. 903 - 912
Silicon is one of the most widely used chemical materials, and the increasing use of silica nanoparticles (SNs) highlights the requirement for safety and... 
MEDICINE, RESEARCH & EXPERIMENTAL | PARTICLES | DNA-DAMAGE | MITOCHONDRIA | NANOMATERIALS | apoptosis | TOXICITY | LUNG-CANCER | IN-VITRO | PATHWAY | silica nanoparticles | human hepatocyte cells | LIVER | INDUCED CYTOTOXICITY | mechanism | cytotoxicity
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148213
Autosomal recessive ataxias are a clinically diverse group of syndromes that in some cases are caused by mutations in genes with roles in the DNA damage... 
RAT-LIVER | LIFE-SPAN | COMPLEX | CAENORHABDITIS-ELEGANS | CEREBELLAR-ATAXIA | MULTIDISCIPLINARY SCIENCES | UBIQUINONE BIOSYNTHESIS | COQ DEFICIENCY | MUTATIONS | COENZYME Q DEFICIENCY | SACCHAROMYCES-CEREVISIAE | Reactive Oxygen Species - metabolism | Oxidative Stress | Humans | Homeostasis | Mitochondrial Proteins - genetics | Saccharomyces cerevisiae - metabolism | Lysosomes - metabolism | RNA Interference | Mitochondrial Proteins - metabolism | Membrane Potential, Mitochondrial | Lentivirus - genetics | Protein Structure, Tertiary | Mutagenesis, Site-Directed | Cell Survival | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Oxidative Phosphorylation | Glutathione Transferase - metabolism | Mitochondria - metabolism | Recombinant Fusion Proteins - chemistry | Endopeptidase K - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cytosol - metabolism | DNA Damage | HeLa Cells | Mutation | Ubiquinone - chemistry | Oxidative stress | Enzymes | Ionizing radiation | Genetic aspects | Genetic transcription | Cerebellum | Phosphorylation | Transcription | Gene regulation | Genes | DNA damage | Biosynthesis | Biology | Kinases | Autophagy | Defects | Proteins | Mitochondria | Coenzyme Q10 | Ataxia | Deoxyribonucleic acid--DNA | Recombinant | Medical research | Cerebellar ataxia | Gene expression | Patients | Microscopy | Cell lines | Cristae | Deoxyribonucleic acid | DNA
Journal Article