Magnetic Resonance in Medicine, ISSN 0740-3194, 04/2018, Volume 79, Issue 4, pp. 2142 - 2148
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2016, Volume 15, Issue 3, pp. 259 - 269
Summary Background Acute demyelinating optic neuritis, a common feature of multiple sclerosis, can damage vision through neurodegeneration in the optic nerve...
Neurology | AXONS | ERYTHROPOIETIN | MULTIPLE-SCLEROSIS | MRI | INTRAVENOUS METHYLPREDNISOLONE | DOUBLE-BLIND | SEGMENTATION | PATHOLOGY | COHERENCE TOMOGRAPHY | CLINICAL NEUROLOGY | Double-Blind Method | Outcome Assessment (Health Care) | Humans | Middle Aged | Male | Voltage-Gated Sodium Channel Blockers - administration & dosage | Phenytoin - administration & dosage | Neuroprotective Agents - pharmacology | Phenytoin - adverse effects | Optic Neuritis - drug therapy | Voltage-Gated Sodium Channel Blockers - pharmacology | Adult | Female | Phenytoin - pharmacology | Neuroprotective Agents - administration & dosage | Voltage-Gated Sodium Channel Blockers - adverse effects | Neurosciences | Care and treatment | Multiple sclerosis | Analysis | Optic neuritis | Clinical trials | Product development | Phenytoin | Studies | Disability | Optic nerve | Sodium | Rodents
Neurology | AXONS | ERYTHROPOIETIN | MULTIPLE-SCLEROSIS | MRI | INTRAVENOUS METHYLPREDNISOLONE | DOUBLE-BLIND | SEGMENTATION | PATHOLOGY | COHERENCE TOMOGRAPHY | CLINICAL NEUROLOGY | Double-Blind Method | Outcome Assessment (Health Care) | Humans | Middle Aged | Male | Voltage-Gated Sodium Channel Blockers - administration & dosage | Phenytoin - administration & dosage | Neuroprotective Agents - pharmacology | Phenytoin - adverse effects | Optic Neuritis - drug therapy | Voltage-Gated Sodium Channel Blockers - pharmacology | Adult | Female | Phenytoin - pharmacology | Neuroprotective Agents - administration & dosage | Voltage-Gated Sodium Channel Blockers - adverse effects | Neurosciences | Care and treatment | Multiple sclerosis | Analysis | Optic neuritis | Clinical trials | Product development | Phenytoin | Studies | Disability | Optic nerve | Sodium | Rodents
Journal Article
Journal of Magnetic Resonance Imaging, ISSN 1053-1807, 03/2014, Volume 39, Issue 3, pp. 617 - 623
Journal Article
Journal of Magnetic Resonance Imaging, ISSN 1053-1807, 03/2014, Volume 39, Issue 3, pp. 617 - 623
Purpose To identify an improved method for measuring spinal cord cross‐sectional area (CSA) using magnetic resonance imaging (MRI) in multiple sclerosis (MS)....
atrophy | spinal cord | MRI | multiple sclerosis | CERVICAL CORD | MAGNETIC-RESONANCE IMAGES | ECHO | TRIAL | AXONAL LOSS | DISABILITY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | INTERFERON BETA-1A | DISEASE PROGRESSION | Severity of Illness Index | Multiple Sclerosis - diagnosis | Reproducibility of Results | Humans | Middle Aged | Image Interpretation, Computer-Assisted | Magnetic Resonance Imaging - methods | Male | Reference Values | Case-Control Studies | Contrast Media | Quality Improvement | Spinal Cord - pathology | Multiple Sclerosis - pathology | Adult | Atrophy - diagnosis | Female | Imaging, Three-Dimensional | Magnetization | Magnetic resonance imaging | Multiple sclerosis
atrophy | spinal cord | MRI | multiple sclerosis | CERVICAL CORD | MAGNETIC-RESONANCE IMAGES | ECHO | TRIAL | AXONAL LOSS | DISABILITY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | INTERFERON BETA-1A | DISEASE PROGRESSION | Severity of Illness Index | Multiple Sclerosis - diagnosis | Reproducibility of Results | Humans | Middle Aged | Image Interpretation, Computer-Assisted | Magnetic Resonance Imaging - methods | Male | Reference Values | Case-Control Studies | Contrast Media | Quality Improvement | Spinal Cord - pathology | Multiple Sclerosis - pathology | Adult | Atrophy - diagnosis | Female | Imaging, Three-Dimensional | Magnetization | Magnetic resonance imaging | Multiple sclerosis
Journal Article
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Full Text
Cervical cord lesion load is associated with disability independently from atrophy in MS
Neurology, ISSN 0028-3878, 01/2015, Volume 84, Issue 4, pp. 367 - 373
OBJECTIVE:To investigate whether spinal cord (SC) lesion load, when quantified on axial images with high in-plane resolution, is associated with disability in...
PROGRESSIVE MULTIPLE-SCLEROSIS | PHASE | AXONAL LOSS | DEMYELINATION | MRI | DISEASE | SPINAL-CORD | NATURAL-HISTORY | BRAIN | CLINICAL NEUROLOGY | POSTMORTEM | Disability Evaluation | Multiple Sclerosis, Relapsing-Remitting - pathology | Multiple Sclerosis, Chronic Progressive - physiopathology | Cervical Cord - pathology | Humans | Middle Aged | Atrophy - pathology | Magnetic Resonance Imaging - methods | Multiple Sclerosis, Chronic Progressive - pathology | Male | Multiple Sclerosis, Relapsing-Remitting - physiopathology | Magnetic Resonance Imaging - instrumentation | Adult | Female | Spinal Cord Diseases - pathology
PROGRESSIVE MULTIPLE-SCLEROSIS | PHASE | AXONAL LOSS | DEMYELINATION | MRI | DISEASE | SPINAL-CORD | NATURAL-HISTORY | BRAIN | CLINICAL NEUROLOGY | POSTMORTEM | Disability Evaluation | Multiple Sclerosis, Relapsing-Remitting - pathology | Multiple Sclerosis, Chronic Progressive - physiopathology | Cervical Cord - pathology | Humans | Middle Aged | Atrophy - pathology | Magnetic Resonance Imaging - methods | Multiple Sclerosis, Chronic Progressive - pathology | Male | Multiple Sclerosis, Relapsing-Remitting - physiopathology | Magnetic Resonance Imaging - instrumentation | Adult | Female | Spinal Cord Diseases - pathology
Journal Article
NMR in Biomedicine, ISSN 0952-3480, 03/2013, Volume 26, Issue 3, pp. 357 - 366
The possibility of quantifying the superimposed signal of glutamate and glutamine (Glx) and its components by 1 H magnetic resonance spectroscopy (MRS) in the...
1 H | STEAM | spinal cord | glutamine | glutamate | PRESS | MRS | Algorithms | Cervical Vertebrae - metabolism | Magnetic Resonance Spectroscopy - methods | Spinal Cord - metabolism | Humans | Adult | Female | Male | Reference Values | Neurotransmitter Agents - analysis | Glutamine - analysis | Glutamic Acid - analysis
1 H | STEAM | spinal cord | glutamine | glutamate | PRESS | MRS | Algorithms | Cervical Vertebrae - metabolism | Magnetic Resonance Spectroscopy - methods | Spinal Cord - metabolism | Humans | Adult | Female | Male | Reference Values | Neurotransmitter Agents - analysis | Glutamine - analysis | Glutamic Acid - analysis
Journal Article
Neurology, ISSN 0028-3878, 04/2018, Volume 90, Issue 14, pp. e1183 - e1190
OBJECTIVE: To assess the value of the central vein sign (CVS) on a clinical 3T scanner to distinguish between multiple sclerosis (MS) and neuromyelitis optica...
d_article_not_yet_freely_accessible | GRADIENT-RECALLED MRI | MULTIPLE-SCLEROSIS | NEUROMYELITIS-OPTICA | BRAIN-LESIONS | TESLA MRI | PERIVENTRICULAR VENOUS DENSITY | OPTICA SPECTRUM DISORDER | CLINICAL NEUROLOGY
d_article_not_yet_freely_accessible | GRADIENT-RECALLED MRI | MULTIPLE-SCLEROSIS | NEUROMYELITIS-OPTICA | BRAIN-LESIONS | TESLA MRI | PERIVENTRICULAR VENOUS DENSITY | OPTICA SPECTRUM DISORDER | CLINICAL NEUROLOGY
Journal Article
NMR in Biomedicine, ISSN 0952-3480, 03/2013, Volume 26, Issue 3, pp. 357 - 366
Journal Article
Magnetic Resonance in Medicine, ISSN 0740-3194, 04/2018, Volume 79, Issue 4, pp. 2142 - 2148
Purpose To develop a fast and robust method for measuring T1 in the whole cervical spinal cord in vivo, and to assess its reproducibility. Methods A spatially...
inversion Recovery | reduced FOV | spinal cord | reproducibility | T1 mapping | mapping | Correlation coefficient | Spinal cord | Correlation coefficients | Magnetic resonance | Regional analysis | Adiabatic | Inversion | Mapping | Substantia grisea | Coefficient of variation | Estimates | Confidence intervals | Medicine | Adiabatic flow | Reproducibility | Data recovery | Imaging | In vivo methods and tests | Resonance
inversion Recovery | reduced FOV | spinal cord | reproducibility | T1 mapping | mapping | Correlation coefficient | Spinal cord | Correlation coefficients | Magnetic resonance | Regional analysis | Adiabatic | Inversion | Mapping | Substantia grisea | Coefficient of variation | Estimates | Confidence intervals | Medicine | Adiabatic flow | Reproducibility | Data recovery | Imaging | In vivo methods and tests | Resonance
Journal Article
NeuroImage, ISSN 1053-8119, 05/2017, Volume 152, pp. 312 - 329
An important image processing step in spinal cord magnetic resonance imaging is the ability to reliably and accurately segment grey and white matter for tissue...
Spinal cord | Segmentation | MRI | Grey matter | Evaluation metrics | Challenge | Neurology | Cognitive Neuroscience | Journal Article | WHITE | ATROPHY | NETWORKS | NEUROSCIENCES | NEUROIMAGING | OF-THE-ART | MULTIPLE-SCLEROSIS | MORPHOMETRY | DISABILITY | OPTIMIZED PATCHMATCH | ASSOCIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GRAY-MATTER | Computer science | Image processing | Biomedical engineering | Brain | Multiple sclerosis | High resolution | Scanning | Scanners | Bacon | Datasets | Head and neck | International conferences | Cross sections | University colleges | Computer vision | Construction | Head | Data acquisition | Images | Ground truth | Sun | Neurological diseases | Artifacts | Thinning | Taxation | Edge detection | Health care | Neuroimaging | Nuclear magnetic resonance--NMR | Identification methods | Spatial discrimination | Intervertebral discs | Substantia grisea | Channels | Pixels | Radio frequency | Atrophy | Bandwidth | Attenuation | Age | Automation | Feasibility studies | Data processing | Substantia alba | Algorithms | Brain research | Magnetic resonance imaging | Magnetic permeability | In vivo methods and tests | Resonance | Acceleration
Spinal cord | Segmentation | MRI | Grey matter | Evaluation metrics | Challenge | Neurology | Cognitive Neuroscience | Journal Article | WHITE | ATROPHY | NETWORKS | NEUROSCIENCES | NEUROIMAGING | OF-THE-ART | MULTIPLE-SCLEROSIS | MORPHOMETRY | DISABILITY | OPTIMIZED PATCHMATCH | ASSOCIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GRAY-MATTER | Computer science | Image processing | Biomedical engineering | Brain | Multiple sclerosis | High resolution | Scanning | Scanners | Bacon | Datasets | Head and neck | International conferences | Cross sections | University colleges | Computer vision | Construction | Head | Data acquisition | Images | Ground truth | Sun | Neurological diseases | Artifacts | Thinning | Taxation | Edge detection | Health care | Neuroimaging | Nuclear magnetic resonance--NMR | Identification methods | Spatial discrimination | Intervertebral discs | Substantia grisea | Channels | Pixels | Radio frequency | Atrophy | Bandwidth | Attenuation | Age | Automation | Feasibility studies | Data processing | Substantia alba | Algorithms | Brain research | Magnetic resonance imaging | Magnetic permeability | In vivo methods and tests | Resonance | Acceleration
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 6/2016, Volume 22, Issue 7, pp. 910 - 920
Background: The in vivo relationship of spinal cord lesion features with clinical course and function in multiple sclerosis (MS) is poorly defined. Objective:...
grey matter | Multiple sclerosis | spinal cord | MRI | ABNORMALITIES | ECHO | PHYSICAL-DISABILITY | DISEASE | CLINICAL DISABILITY | HISTOPATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | Disability Evaluation | Severity of Illness Index | Demyelinating Diseases - diagnostic imaging | Demyelinating Diseases - physiopathology | Multiple Sclerosis, Chronic Progressive - physiopathology | Predictive Value of Tests | Cervical Vertebrae | White Matter - physiopathology | Cross-Sectional Studies | Humans | Middle Aged | Spinal Cord - diagnostic imaging | Male | Multiple Sclerosis, Chronic Progressive - diagnostic imaging | Multiple Sclerosis, Relapsing-Remitting - physiopathology | Disease Progression | Young Adult | Magnetic Resonance Imaging | White Matter - diagnostic imaging | Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging | Adult | Female | Spinal Cord - physiopathology | Spinal cord | Magnetic resonance imaging | Substantia alba | Substantia grisea
grey matter | Multiple sclerosis | spinal cord | MRI | ABNORMALITIES | ECHO | PHYSICAL-DISABILITY | DISEASE | CLINICAL DISABILITY | HISTOPATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | Disability Evaluation | Severity of Illness Index | Demyelinating Diseases - diagnostic imaging | Demyelinating Diseases - physiopathology | Multiple Sclerosis, Chronic Progressive - physiopathology | Predictive Value of Tests | Cervical Vertebrae | White Matter - physiopathology | Cross-Sectional Studies | Humans | Middle Aged | Spinal Cord - diagnostic imaging | Male | Multiple Sclerosis, Chronic Progressive - diagnostic imaging | Multiple Sclerosis, Relapsing-Remitting - physiopathology | Disease Progression | Young Adult | Magnetic Resonance Imaging | White Matter - diagnostic imaging | Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging | Adult | Female | Spinal Cord - physiopathology | Spinal cord | Magnetic resonance imaging | Substantia alba | Substantia grisea
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164890
Diffusion tensor imaging (DTI) has recently started to be adopted into clinical investigations of spinal cord (SC) diseases. However, DTI applications to the...
FIBERS | MATTER | ECHO | MRI | MULTIDISCIPLINARY SCIENCES | DISABILITY | INJURY | DTI | BLADDER DYSFUNCTION | THE-ART | BRAIN | Reproducibility of Results | Humans | Middle Aged | Signal-To-Noise Ratio | Spinal Cord - diagnostic imaging | Male | Healthy Volunteers | Gray Matter - diagnostic imaging | Young Adult | Magnetic Resonance Imaging | Pilot Projects | White Matter - diagnostic imaging | Image Processing, Computer-Assisted | Adult | Female | Anisotropy | Sexual disorders | Coils | Spinal cord | Multiple sclerosis | Nuclear magnetic resonance--NMR | Biomedical research | Bladder | Health physics | Coefficient of variation | Urinary bladder | Mathematical analysis | Imaging | Diffusion | Biomedical engineering | Enlargement | Medical research | Data acquisition | Feasibility studies | Sexual behavior | Field of view | Substantia alba | Neurology | Brain research | Hospitals | Magnetic resonance imaging | Echo surveys | Reproducibility | In vivo methods and tests | Spinal cord injuries | Nuclear magnetic resonance | NMR
FIBERS | MATTER | ECHO | MRI | MULTIDISCIPLINARY SCIENCES | DISABILITY | INJURY | DTI | BLADDER DYSFUNCTION | THE-ART | BRAIN | Reproducibility of Results | Humans | Middle Aged | Signal-To-Noise Ratio | Spinal Cord - diagnostic imaging | Male | Healthy Volunteers | Gray Matter - diagnostic imaging | Young Adult | Magnetic Resonance Imaging | Pilot Projects | White Matter - diagnostic imaging | Image Processing, Computer-Assisted | Adult | Female | Anisotropy | Sexual disorders | Coils | Spinal cord | Multiple sclerosis | Nuclear magnetic resonance--NMR | Biomedical research | Bladder | Health physics | Coefficient of variation | Urinary bladder | Mathematical analysis | Imaging | Diffusion | Biomedical engineering | Enlargement | Medical research | Data acquisition | Feasibility studies | Sexual behavior | Field of view | Substantia alba | Neurology | Brain research | Hospitals | Magnetic resonance imaging | Echo surveys | Reproducibility | In vivo methods and tests | Spinal cord injuries | Nuclear magnetic resonance | NMR
Journal Article
Annals of Clinical and Translational Neurology, ISSN 2328-9503, 09/2017, Volume 4, Issue 9, pp. 663 - 679
Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal cord is limited by low specificity regarding the underlying...
ORIENTATION DISPERSION | DENSITY | APPEARING WHITE-MATTER | HUMAN BRAIN | AXONAL LOSS | DEMYELINATION | QUANTIFICATION | DIFFUSION MRI | IN-VIVO | RELAXATION-TIMES | NEUROSCIENCES | CLINICAL NEUROLOGY | Pathology | Multiple sclerosis | Spinal cord | Scholarships & fellowships | Nuclear magnetic resonance--NMR | Research funding | Morphology | Biomarkers | Histology | Clinical outcomes
ORIENTATION DISPERSION | DENSITY | APPEARING WHITE-MATTER | HUMAN BRAIN | AXONAL LOSS | DEMYELINATION | QUANTIFICATION | DIFFUSION MRI | IN-VIVO | RELAXATION-TIMES | NEUROSCIENCES | CLINICAL NEUROLOGY | Pathology | Multiple sclerosis | Spinal cord | Scholarships & fellowships | Nuclear magnetic resonance--NMR | Research funding | Morphology | Biomarkers | Histology | Clinical outcomes
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e105544
Histopathological studies have demonstrated the involvement of spinal cord grey matter (GM) and white matter (WM) in several diseases and recent research has...
MULTIPLE SYSTEM ATROPHY | IMPACT | MULTIDISCIPLINARY SCIENCES | SEGMENTATION | SPINAL-CORD-INJURY | AMYOTROPHIC-LATERAL-SCLEROSIS | CONUS MEDULLARIS | DYSFUNCTION | TERMINATION | VERTEBRAL LEVEL | OF-THE-ART | Reproducibility of Results | Humans | Spinal Cord - diagnostic imaging | Magnetic Resonance Imaging - methods | Male | Feasibility Studies | Gray Matter - diagnostic imaging | Radiography | Young Adult | White Matter - diagnostic imaging | Lumbosacral Region | Adult | Female | Observer Variation | Fecal incontinence | Spinal cord | Image resolution | Multiple sclerosis | Nuclear magnetic resonance--NMR | Feasibility studies | Substantia alba | Coefficient of variation | Substantia grisea | Image acquisition | Neurology | Magnetic resonance imaging | Reproducibility | Biomarkers | Informed consent | Feasibility | Spinal cord injuries | Cross sections | Enlargement | NMR | Nuclear magnetic resonance
MULTIPLE SYSTEM ATROPHY | IMPACT | MULTIDISCIPLINARY SCIENCES | SEGMENTATION | SPINAL-CORD-INJURY | AMYOTROPHIC-LATERAL-SCLEROSIS | CONUS MEDULLARIS | DYSFUNCTION | TERMINATION | VERTEBRAL LEVEL | OF-THE-ART | Reproducibility of Results | Humans | Spinal Cord - diagnostic imaging | Magnetic Resonance Imaging - methods | Male | Feasibility Studies | Gray Matter - diagnostic imaging | Radiography | Young Adult | White Matter - diagnostic imaging | Lumbosacral Region | Adult | Female | Observer Variation | Fecal incontinence | Spinal cord | Image resolution | Multiple sclerosis | Nuclear magnetic resonance--NMR | Feasibility studies | Substantia alba | Coefficient of variation | Substantia grisea | Image acquisition | Neurology | Magnetic resonance imaging | Reproducibility | Biomarkers | Informed consent | Feasibility | Spinal cord injuries | Cross sections | Enlargement | NMR | Nuclear magnetic resonance
Journal Article