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Nature, ISSN 0028-0836, 02/2010, Volume 463, Issue 7283, pp. 958 - 962
Heterozygous mutations in the gene encoding the CHD (chromo-domain helicase DNA-binding domain) member CHD7, an ATP-dependent chromatin remodeller homologous... 
NETWORK | COMPLEX | PROTEIN | CHROMATIN | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | TRANSCRIPTION | POLYMERASE-II | MUTATIONS | EXPRESSION | CHARGE-SYNDROME | Embryonic Stem Cells - metabolism | Embryo, Nonmammalian - cytology | Embryonic Stem Cells - cytology | Xenopus Proteins - genetics | Humans | Multipotent Stem Cells - metabolism | Embryo, Nonmammalian - metabolism | Embryo, Nonmammalian - embryology | DNA-Binding Proteins - deficiency | Neural Crest - metabolism | Xenopus Proteins - chemistry | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Developmental | Transcription, Genetic | Cell Differentiation | Xenopus laevis - genetics | DNA Helicases - genetics | Snail Family Transcription Factors | SOX9 Transcription Factor - metabolism | Cell Line | DNA Helicases - chemistry | Neural Crest - cytology | Xenopus laevis - embryology | Chromosomal Proteins, Non-Histone - metabolism | DNA Helicases - deficiency | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Syndrome | Chromosomal Proteins, Non-Histone - genetics | Transcription Factors - metabolism | Cell Lineage | DNA Helicases - metabolism | Animals | Xenopus Proteins - deficiency | Multipotent Stem Cells - cytology | Neural Crest - embryology | Xenopus laevis - metabolism | Twist-Related Protein 1 - genetics | Protein Binding | Xenopus Proteins - metabolism | Enhancer Elements, Genetic - genetics | Twist-Related Protein 1 - metabolism | SOX9 Transcription Factor - genetics | Cell Movement | Chromatin | Drosophila | Polybrominated biphenyls | Physiological aspects | Genetic aspects | Research | Structure | Embryonic stem cells | Helicases | Proteins | Labeling | Evacuations & rescues | Cell adhesion & migration | Human | Peripheral nervous system | Genes | Charge | Bones | Activation | Numerical control | Gene expression
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7520, pp. 102 - 106
The role of long noncoding RNA(lncRNA) in adult hearts is unknown; also unclear is how lncRNA modulates nucleosome remodelling. An estimated 70% of mouse genes... 
MORPHOGENESIS | DOMAIN | CHROMATIN | GENE | RECOGNITION | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | IN-VIVO | TRANSCRIPTION | GROWTH | Chromatin - metabolism | Transcription Factors - chemistry | Humans | Myosin Heavy Chains - genetics | Cardiomegaly - pathology | Cardiomyopathies - prevention & control | Heart Failure - prevention & control | Cardiomyopathies - genetics | Myocardium - metabolism | Nuclear Proteins - genetics | DNA Helicases - genetics | Protein Structure, Tertiary | DNA Helicases - chemistry | Cardiac Myosins - genetics | Chromatin Assembly and Disassembly | Cardiomyopathies - pathology | Heart Failure - genetics | Histone Deacetylases - metabolism | Myocardium - pathology | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | RNA, Long Noncoding - genetics | Heart Failure - pathology | Transcription Factors - genetics | Nuclear Proteins - chemistry | Organ Specificity | Transcription Factors - metabolism | DNA Helicases - metabolism | Feedback, Physiological | Poly(ADP-ribose) Polymerases - metabolism | Animals | Cardiomegaly - prevention & control | Nuclear Proteins - antagonists & inhibitors | Protein Binding | Mice | DNA Helicases - antagonists & inhibitors | Poly (ADP-Ribose) Polymerase-1 | Cardiomegaly - genetics | RNA, Long Noncoding - antagonists & inhibitors | Chromatin - genetics | RNA, Long Noncoding - metabolism | Heart | Physiological aspects | Genetic aspects | RNA | Hypertrophy | Pathology | Cardiomyocytes | RNA polymerase | Ribonucleic acid--RNA | Cardiomyopathy | Rodents
Journal Article
Journal of Gastrointestinal Surgery, ISSN 1091-255X, 1/2019, Volume 23, Issue 1, pp. 179 - 180
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 02/2007, Volume 100, Issue 3, pp. 639 - 649
Peroxynitrite (PON, ONOO−), formed by nitric oxide synthase‐generated nitric oxide radical (˙NO) and superoxide radical (O2˙−), is a crucial player in... 
spinal cord injury | α‐spectrin | calpain | oxidative damage | peroxynitrite | reactive oxygen species | Calpain | Peroxynitrite | Reactive oxygen species | α-spectrin | Spinal cord injury | Oxidative damage | LIPID-PEROXIDATION PRODUCT | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTIVATED NEUTRAL PROTEASE | NEUROSCIENCES | NERVOUS-SYSTEM TRAUMA | RADICAL FORMATION | TRAUMATIC BRAIN-INJURY | CALPAIN ACTIVITY | IMPAIRED MITOCHONDRIAL | CALCIUM | NITRIC-OXIDE | alpha-spectrin | Free Radical Scavengers - pharmacology | Calpain - metabolism | Spinal Cord Injuries - drug therapy | Calcium Signaling - physiology | Oxidative Stress - physiology | Nerve Degeneration - physiopathology | Aldehydes - metabolism | Tyrosine - analogs & derivatives | Nerve Degeneration - metabolism | Time Factors | Up-Regulation - physiology | Free Radicals - metabolism | Female | Free Radical Scavengers - therapeutic use | Spectrin - metabolism | Biomarkers - metabolism | Peptide Fragments - metabolism | Spinal Cord Injuries - metabolism | Rats | Rats, Sprague-Dawley | Disease Progression | Lipid Peroxidation - physiology | Tyrosine - metabolism | Animals | Peroxynitrous Acid - metabolism | Spinal Cord Injuries - physiopathology | Nerve Degeneration - etiology | Nitric Oxide - metabolism | Enzymes | Oxidation | Spinal cord injuries | Trauma | Nitric oxide | Rodents
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1738 - 1743
Development of the cerebral vessels, pharyngeal arch arteries (PAAs). and cardiac outflow tract (OFT) requires multipotent neural crest cells (NCCs) that... 
Statistical significance | Chromatin | Developmental biology | Neurons | Forebrain | CHARGE syndrome | Gene expression regulation | Embryos | Neural crest | Apoptosis | HEART | CARDIAC OUTFLOW TRACT | CARDIOVASCULAR DEVELOPMENT | APOPTOSIS | MORPHOGENESIS | TARGETED DISRUPTION | MULTIDISCIPLINARY SCIENCES | SMOOTH-MUSCLE-CELLS | SEPTATION | CHARGE-SYNDROME | SEMAPHORIN 3C | Cell Proliferation | Multipotent Stem Cells - metabolism | Myosin Heavy Chains - genetics | Apoptosis - genetics | Myosin Heavy Chains - metabolism | Cell Movement - genetics | Neural Crest - metabolism | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | In Situ Hybridization | RNA Interference | Gene Expression Regulation, Developmental | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | MAP Kinase Kinase Kinase 5 - metabolism | Nuclear Proteins - genetics | DNA Helicases - genetics | Cardiovascular System - embryology | Neural Crest - cytology | MAP Kinase Kinase Kinase 5 - genetics | Embryo, Mammalian - blood supply | Cells, Cultured | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Pregnancy | Transcription Factors - metabolism | DNA Helicases - metabolism | Animals | Cardiovascular System - metabolism | Embryo, Mammalian - embryology | Embryo, Mammalian - cytology | Neural Crest - embryology | Mice | Mutation | Neural Stem Cells - metabolism | Cardiovascular System - cytology | Microscopy, Fluorescence | Embryonic development | Physiological aspects | Cytogenetics | Genetic aspects | Research | Gene expression | Health aspects | Phosphotransferases | Biological Sciences
Journal Article
American Journal of Clinical Pathology, ISSN 0002-9173, 01/2018, Volume 149, Issue suppl_1, pp. S102 - S103
Abstract Objectives Current classification of squamous cell carcinoma precursors includes two distinct categories: HPV-dependent low-grade or high-grade... 
Journal Article
Experimental Neurology, ISSN 0014-4886, 2009, Volume 216, Issue 1, pp. 105 - 114
Evidence suggests that the reactive oxygen species peroxynitrite (PN) is an important player in the pathophysiology of acute spinal cord injury (SCI). In the... 
Peroxynitrite | Mitochondrial dysfunction | Oxidative damage | Protein nitration | Tempol | Lipid peroxidation | Spinal cord injury | Cytoskeletal breakdown | LIPID-PEROXIDATION | NEUROSCIENCES | NERVOUS-SYSTEM TRAUMA | DEPENDENT TOXICITY | MITOCHONDRIAL PERMEABILITY TRANSITION | TRAUMATIC BRAIN-INJURY | NITROXIDE RADICALS | MOUSE MODEL | NITRIC-OXIDE | CYTOTOXIC PATHWAY | Calpain - metabolism | Spinal Cord - drug effects | Spinal Cord - metabolism | Spinal Cord Injuries - drug therapy | Calcium Signaling - physiology | Oxidative Stress - physiology | Nerve Degeneration - physiopathology | Spectrin - drug effects | Spin Labels | Nerve Degeneration - metabolism | Cyclic N-Oxides - pharmacology | Cell Respiration - drug effects | Cell Respiration - physiology | Lipid Peroxidation - drug effects | Free Radicals - metabolism | Female | Peroxynitrous Acid - antagonists & inhibitors | Spectrin - metabolism | Disease Models, Animal | Drug Administration Schedule | Spinal Cord Injuries - metabolism | Rats | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Calpain - drug effects | Rats, Sprague-Dawley | Lipid Peroxidation - physiology | Free Radicals - antagonists & inhibitors | Animals | Calcium Signaling - drug effects | Peroxynitrous Acid - metabolism | Spinal Cord - physiopathology | Spinal Cord Injuries - physiopathology | Oxidative Stress - drug effects | Nerve Degeneration - drug therapy | Nitration | Analysis | Brain damage | Mitochondrial DNA | Spinal cord injuries | Free radicals (Chemistry) | Membrane proteins
Journal Article
American Journal of Clinical Pathology, ISSN 0002-9173, 10/2018, Volume 150, Issue 6, pp. 485 - 490
Abstract Objectives To develop a curriculum for a commercial reference laboratory clinical pathology training elective. Methods A 4-day elective at Quest... 
Laboratory management | Reference laboratory | Resident training | Clinical pathology elective rotation | CURRICULUM | FELLOWS | PATHOLOGY | Pathology | Laboratories | Curricula
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 06/2017, Volume 95, Issue 6, pp. 601 - 613
Renal fibrosis is the most common outcome of chronic kidney disease (CKD), while the pathogenesis of renal fibrosis is not fully understood. In this study, we... 
DNA methylation | sFRP5 | Renal fibrosis | Indoxyl sulfate | Wnt/β-catenin | TUBULAR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | P-CRESYL SULFATE | BOUND UREMIC TOXINS | SIGNALING PATHWAY | Wnt/beta-catenin | PROSTATE-CANCER | GENETICS & HEREDITY | TUBULOINTERSTITIAL FIBROSIS | GENE-EXPRESSION | CHRONIC KIDNEY-DISEASE | CELL-CARCINOMA | Cell Line | Kidney - drug effects | Reactive Oxygen Species - metabolism | Kidney - pathology | Membrane Proteins - genetics | Humans | Indican - blood | MAP Kinase Signaling System | Renal Insufficiency, Chronic - pathology | Renal Insufficiency, Chronic - blood | Renal Insufficiency, Chronic - metabolism | DNA Methylation | Kidney - metabolism | Eye Proteins - metabolism | Fibrosis | Renal Insufficiency, Chronic - genetics | Membrane Proteins - metabolism | Eye Proteins - genetics | Wnt Signaling Pathway | Physiological aspects | Development and progression | Genetic aspects | Cellular signal transduction | Research | Methylation | Wnt protein | Pathogenesis | Activation | Sulfates | β-catenin | Rodents | Attenuation | Inhibition | Islands | Deoxyribonucleic acid--DNA | Activation analysis | Recombinant | CpG islands | Kidneys | Messages | Extracellular signal-regulated kinase | Gene expression | Patients | Serum levels | Mice | Sulfate | In vitro methods and tests | 5-aza-2'-deoxycytidine | Kidney transplantation
Journal Article
International Journal of Surgical Pathology, ISSN 1066-8969, 5/2019, Volume 27, Issue 3, pp. 259 - 262
Objectives. Transducer-like enhancer of split 1 (TLE1) immunohistochemistry is widely used as a biomarker of synovial sarcoma. Spindle cell or desmoplastic... 
desmoplastic | synovial sarcoma | melanoma | spindle cell | TLE1 | immunohistochemistry | SURGERY | ENHANCER | PATHOLOGY | IMMUNOHISTOCHEMICAL MARKER
Journal Article
Journal Article