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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 08/2004, Volume 114, Issue 4, pp. 475 - 484
Receptor activator of NF-kappaB ligand (RANKL) plays an essential role in osteoclast formation and bone resorption. Although genetic and biochemical studies... 
MEDICINE, RESEARCH & EXPERIMENTAL | LYMPH-NODE ORGANOGENESIS | PROTEIN | KEY REGULATOR | INDUCED APOPTOSIS | KINASE | OSTEOBLASTIC DIFFERENTIATION | DEFECTIVE INTERLEUKIN-1 | RECEPTOR | KAPPA-B | LIGAND
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2005, Volume 386, Issue 3, pp. 150 - 155
Kainate stimulation induces the expression of immediate early genes, c- fos and c- jun genes. Trichostatin A (TSA), a potent histone deacetylase (HDAC) enzyme... 
Trichostatin A | Histone acetylation | c- fos gene | Kainic acid | c- jun gene | Hippocampus | c-jun gene | c-fos gene | CONSOLIDATION | kainic acid | SEIZURES | hippocampus | trichostatin A | STATUS EPILEPTICUS | EXPRESSION | NEUROSCIENCES | histone acetylation | Pyramidal Cells - metabolism | Genes, Immediate-Early - physiology | Proto-Oncogene Proteins c-jun - biosynthesis | Transcriptional Activation - drug effects | Proto-Oncogene Proteins c-fos - biosynthesis | Male | Hippocampus - drug effects | Drug Interactions | Time Factors | Neurons - metabolism | Pyramidal Cells - drug effects | Neurons - drug effects | Hydroxamic Acids - pharmacology | Proto-Oncogene Proteins c-jun - genetics | Kainic Acid - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Histone Deacetylases - metabolism | Excitatory Amino Acid Agonists - pharmacology | Mice, Inbred ICR | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Acetylation - drug effects | Genes, Immediate-Early - drug effects | Animals | Proto-Oncogene Proteins c-fos - genetics | Histone Deacetylase Inhibitors | Mice | Transcriptional Activation - physiology | Histones - metabolism | Enzymes | Cell research | Messenger RNA | Enzyme inhibitors | Neurons | Analysis | Genetic research | Genetic aspects | Gene expression
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2004, Volume 114, Issue 4, pp. 475 - 484
Journal Article
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 06/2008, Volume 23, Issue 6, pp. 907 - 914
Introduction: RANKL is known to be important not only for differentiation and activation of osteoclasts but also for their survival. Experimentally, apoptosis... 
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 08/2004, Volume 114, Issue 4, pp. 475 - 484
Journal Article
Journal Article
Neurochemistry International, ISSN 0197-0186, 2004, Volume 45, Issue 5, pp. 765 - 772
Recent papers have reported that neuronal death in patients with Alzheimer’s disease, Parkinson’s disease, and cerebral ischemia has its origin in the... 
JAB1 | Endoplasmic reticulum | Stress | IRE1α | Unfolded protein response | c-Jun N-terminal kinase | XBP1 | AD | Parkinson's disease | JNK | PERK | PKR-like ER kinase | ER | unfolded protein response | Jun activation domain-binding protein-1 | TG | PD | UPR | TM | Alzheimer's disease | thapsigargin | X-box protein 1 | endoplasmic reticulum | tunicamycin | TRANSCRIPTION FACTORS | stress | ACTIVATION | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ENDOPLASMIC-RETICULUM STRESS | NEUROSCIENCES | PRESENILIN-1 MUTATIONS | MESSENGER-RNA | TRANSDUCERS | COP9 SIGNALOSOME | IRE1 alpha | DISEASE | Immunohistochemistry | Antibodies - chemistry | Humans | DNA, Complementary - genetics | Saccharomyces cerevisiae - metabolism | Mutation - physiology | Membrane Proteins - physiology | Endoplasmic Reticulum - drug effects | DNA, Complementary - biosynthesis | Nucleotide Mapping | Cell Line | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - physiology | Endoplasmic Reticulum - physiology | Protein-Serine-Threonine Kinases - genetics | Intracellular Signaling Peptides and Proteins | COP9 Signalosome Complex | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Precipitin Tests | Protein Folding | Endoribonucleases | Cell Death - physiology | Peptide Hydrolases
Journal Article