International Journal of Molecular Sciences, ISSN 1661-6596, 08/2016, Volume 17, Issue 8, pp. 1246 - 1246
In this research, we firstly demonstrated that physcion, an anthraquinone derivative, specifically increased the expression of the human alpha...
Signal pathway | HST8Sia VI | Transcription factor Pax-5 | Physcion | SK-N-BE-C | PREPARATIVE ISOLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | VALPROIC ACID | hST8Sia VI | MEDIATED TRANSCRIPTIONAL REGULATION | PAX5 | IDENTIFICATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | SIALYLTRANSFERASES | COUNTER-CURRENT CHROMATOGRAPHY | ANTHRAQUINONES | SYNTHASE HST8SIA I | signal pathway | physcion | transcription factor Pax-5 | Gene Expression Regulation, Enzymologic - drug effects | Sequence Deletion | Transcriptional Activation - genetics | Apoptosis - drug effects | Emodin - analogs & derivatives | Humans | Neuroblastoma - enzymology | Transcriptional Activation - drug effects | Cell Survival - genetics | Apoptosis - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | 5' Flanking Region - genetics | Base Sequence | p38 Mitogen-Activated Protein Kinases - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Cell Survival - drug effects | Promoter Regions, Genetic | Brain Neoplasms - enzymology | Emodin - pharmacology | Emodin - isolation & purification | Neuroblastoma - genetics | RNA, Messenger - genetics | Sialyltransferases - genetics | Brain Neoplasms - genetics | Up-Regulation - genetics | Emodin - chemistry | Sialyltransferases - metabolism | Sequence Analysis, DNA | Up-Regulation - drug effects | Cell Line, Tumor | Cellular biology | Gene expression | Research
Signal pathway | HST8Sia VI | Transcription factor Pax-5 | Physcion | SK-N-BE-C | PREPARATIVE ISOLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | VALPROIC ACID | hST8Sia VI | MEDIATED TRANSCRIPTIONAL REGULATION | PAX5 | IDENTIFICATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | SIALYLTRANSFERASES | COUNTER-CURRENT CHROMATOGRAPHY | ANTHRAQUINONES | SYNTHASE HST8SIA I | signal pathway | physcion | transcription factor Pax-5 | Gene Expression Regulation, Enzymologic - drug effects | Sequence Deletion | Transcriptional Activation - genetics | Apoptosis - drug effects | Emodin - analogs & derivatives | Humans | Neuroblastoma - enzymology | Transcriptional Activation - drug effects | Cell Survival - genetics | Apoptosis - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | 5' Flanking Region - genetics | Base Sequence | p38 Mitogen-Activated Protein Kinases - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Cell Survival - drug effects | Promoter Regions, Genetic | Brain Neoplasms - enzymology | Emodin - pharmacology | Emodin - isolation & purification | Neuroblastoma - genetics | RNA, Messenger - genetics | Sialyltransferases - genetics | Brain Neoplasms - genetics | Up-Regulation - genetics | Emodin - chemistry | Sialyltransferases - metabolism | Sequence Analysis, DNA | Up-Regulation - drug effects | Cell Line, Tumor | Cellular biology | Gene expression | Research
Journal Article
Apoptosis, ISSN 1360-8185, 9/2017, Volume 22, Issue 9, pp. 1079 - 1097
Fluoxetine (FLX) is an antidepressant drug that belongs to the class of selective serotonin reuptake inhibitors. FLX is known to induce apoptosis in multiple...
Biochemistry, general | Biomedicine | Fluoxetine | Histone hyperacetylation | SK-N-BE-M17 cells | ER stress | Cancer Research | Oncology | Cell Biology | Virology | Apoptosis | MAPKs | ANTIDEPRESSANT | CANCER CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | DEATH | CELL BIOLOGY | NUCLEAR-FACTOR | SODIUM-BUTYRATE | DRUGS | MITOCHONDRIAL DYSFUNCTION | INHIBITORS | UP-REGULATION | Cell Survival - drug effects | Fluoxetine - pharmacology | Transcription Factor CHOP - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Endoplasmic Reticulum Stress - drug effects | MAP Kinase Kinase Kinase 5 - genetics | Apoptosis - drug effects | Humans | Transcription Factor CHOP - antagonists & inhibitors | Membrane Potential, Mitochondrial - drug effects | Gene Knockdown Techniques | Acetylation - drug effects | Animals | Caspases, Initiator - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Histones - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Neuroblastoma - pathology | Medical colleges | Histones | Research institutes | Neuroblastoma | Molecular biology | Mitogens | Protein kinases | Chromatin | Homology | Serotonin uptake inhibitors | Event-related potentials | Activation | CCAAT/enhancer-binding protein | Kinases | Caspase-4 | Neuroblastoma cells | Anticancer properties | Proteins | Mitochondria | Cell activation | Transfection | Membrane potential | Inhibition | Acetylation | Stresses | Serotonin | Mortality | Extracellular signal-regulated kinase | Caspase | MAP kinase | JNK protein | siRNA | Histone acetyltransferase | Stress | Molecular modelling | Inhibitors | Acids | Protein kinase | Cell death | Endoplasmic reticulum | Histone H3 | Phenylbutyric acid | Cancer
Biochemistry, general | Biomedicine | Fluoxetine | Histone hyperacetylation | SK-N-BE-M17 cells | ER stress | Cancer Research | Oncology | Cell Biology | Virology | Apoptosis | MAPKs | ANTIDEPRESSANT | CANCER CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | DEATH | CELL BIOLOGY | NUCLEAR-FACTOR | SODIUM-BUTYRATE | DRUGS | MITOCHONDRIAL DYSFUNCTION | INHIBITORS | UP-REGULATION | Cell Survival - drug effects | Fluoxetine - pharmacology | Transcription Factor CHOP - genetics | Phosphorylation | Reactive Oxygen Species - metabolism | Endoplasmic Reticulum Stress - drug effects | MAP Kinase Kinase Kinase 5 - genetics | Apoptosis - drug effects | Humans | Transcription Factor CHOP - antagonists & inhibitors | Membrane Potential, Mitochondrial - drug effects | Gene Knockdown Techniques | Acetylation - drug effects | Animals | Caspases, Initiator - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Histones - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Neuroblastoma - pathology | Medical colleges | Histones | Research institutes | Neuroblastoma | Molecular biology | Mitogens | Protein kinases | Chromatin | Homology | Serotonin uptake inhibitors | Event-related potentials | Activation | CCAAT/enhancer-binding protein | Kinases | Caspase-4 | Neuroblastoma cells | Anticancer properties | Proteins | Mitochondria | Cell activation | Transfection | Membrane potential | Inhibition | Acetylation | Stresses | Serotonin | Mortality | Extracellular signal-regulated kinase | Caspase | MAP kinase | JNK protein | siRNA | Histone acetyltransferase | Stress | Molecular modelling | Inhibitors | Acids | Protein kinase | Cell death | Endoplasmic reticulum | Histone H3 | Phenylbutyric acid | Cancer
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2014, Volume 289, Issue 45, pp. 31458 - 31472
p75 is expressed among Purkinje cells in the adult cerebellum, but its function has remained obscure. Here we report that p75 is involved in maintaining the...
CONDUCTANCE | CEREBELLAR | NMDA RECEPTOR | ACTIVATION | PROTEIN | BDNF | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | RHO-GTPASES | EXPRESSION | Tetraethylammonium - chemistry | Purkinje Cells - metabolism | Membrane Glycoproteins - metabolism | Signal Transduction | Protein-Tyrosine Kinases - metabolism | Cerebellum - metabolism | Mice, Inbred C57BL | Electrophysiology | rac GTP-Binding Proteins - metabolism | Neuropeptides - metabolism | Receptors, Nerve Growth Factor - metabolism | Synaptosomes - metabolism | Microscopy, Electron | Small-Conductance Calcium-Activated Potassium Channels - metabolism | Mice, Knockout | Potassium Channels - metabolism | Patch-Clamp Techniques | Animals | Golgi Apparatus - metabolism | Mice | rac1 GTP-Binding Protein - metabolism | Cerebellum | Potassium Channel | Neurobiology | Purkinje Cells | Brain-derived Neurotrophic Factor (BDNF) | p75 Neurotrophin Receptor | Patch Clamp | Rac1 | SK Channels
CONDUCTANCE | CEREBELLAR | NMDA RECEPTOR | ACTIVATION | PROTEIN | BDNF | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | RHO-GTPASES | EXPRESSION | Tetraethylammonium - chemistry | Purkinje Cells - metabolism | Membrane Glycoproteins - metabolism | Signal Transduction | Protein-Tyrosine Kinases - metabolism | Cerebellum - metabolism | Mice, Inbred C57BL | Electrophysiology | rac GTP-Binding Proteins - metabolism | Neuropeptides - metabolism | Receptors, Nerve Growth Factor - metabolism | Synaptosomes - metabolism | Microscopy, Electron | Small-Conductance Calcium-Activated Potassium Channels - metabolism | Mice, Knockout | Potassium Channels - metabolism | Patch-Clamp Techniques | Animals | Golgi Apparatus - metabolism | Mice | rac1 GTP-Binding Protein - metabolism | Cerebellum | Potassium Channel | Neurobiology | Purkinje Cells | Brain-derived Neurotrophic Factor (BDNF) | p75 Neurotrophin Receptor | Patch Clamp | Rac1 | SK Channels
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 09/2012, Volume 26, Issue 6, pp. 783 - 790
► An NASH model was created in SK-Hep-1 cells using palmitic acid and TNF-α. ► Palmitic acid promoted TNF-α-induced cytotoxicity by blocking survival...
AKT | Free fatty acid | TNF-α | NASH | Apoptosis | KAPPA-B ACTIVATION | TNF-alpha | FATTY LIVER-DISEASE | NONALCOHOLIC STEATOHEPATITIS | DEATH | TUMOR-NECROSIS-FACTOR | CULTURED RAT HEPATOCYTES | INSULIN-RESISTANCE | TOXICOLOGY | STRESS | UP-REGULATION | Caspase 7 - metabolism | Malondialdehyde - metabolism | Cell Survival - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Fatty Liver - metabolism | Glutathione - metabolism | Humans | Caspase 3 - metabolism | Non-alcoholic Fatty Liver Disease | Cell Line, Tumor | Fatty Acids - pharmacology
AKT | Free fatty acid | TNF-α | NASH | Apoptosis | KAPPA-B ACTIVATION | TNF-alpha | FATTY LIVER-DISEASE | NONALCOHOLIC STEATOHEPATITIS | DEATH | TUMOR-NECROSIS-FACTOR | CULTURED RAT HEPATOCYTES | INSULIN-RESISTANCE | TOXICOLOGY | STRESS | UP-REGULATION | Caspase 7 - metabolism | Malondialdehyde - metabolism | Cell Survival - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Fatty Liver - metabolism | Glutathione - metabolism | Humans | Caspase 3 - metabolism | Non-alcoholic Fatty Liver Disease | Cell Line, Tumor | Fatty Acids - pharmacology
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2013, Volume 434, Issue 3, pp. 503 - 508
MicroRNA (miRNA) is a class of endogenous small noncoding RNA that negatively regulates gene expression at the post-transcriptional level and plays an...
miR-96 | Insulin resistance | MicroRNA | Mitochondrial dysfunction | IRS-1 | MiR-96 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSCLE | MECHANISMS | GLUCOSE-UTILIZATION | MICRORNAS | OBESE WOMEN | BIOPHYSICS | INSULIN-RESISTANCE | TARGETS | TRANSCRIPTION FACTOR | EXPRESSION | MIR-182 | Up-Regulation | Insulin - metabolism | Protein Biosynthesis | Signal Transduction | Electrophoresis, Polyacrylamide Gel | Humans | Glycogen - biosynthesis | Cell Line, Tumor | MicroRNAs - biosynthesis | 3' Untranslated Regions | Insulin Receptor Substrate Proteins - genetics | Mitochondria - physiology
miR-96 | Insulin resistance | MicroRNA | Mitochondrial dysfunction | IRS-1 | MiR-96 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUSCLE | MECHANISMS | GLUCOSE-UTILIZATION | MICRORNAS | OBESE WOMEN | BIOPHYSICS | INSULIN-RESISTANCE | TARGETS | TRANSCRIPTION FACTOR | EXPRESSION | MIR-182 | Up-Regulation | Insulin - metabolism | Protein Biosynthesis | Signal Transduction | Electrophoresis, Polyacrylamide Gel | Humans | Glycogen - biosynthesis | Cell Line, Tumor | MicroRNAs - biosynthesis | 3' Untranslated Regions | Insulin Receptor Substrate Proteins - genetics | Mitochondria - physiology
Journal Article
BMC Cancer, ISSN 1471-2407, 05/2013, Volume 13, Issue 1, pp. 261 - 261
Background: Cell adhesion molecules (CAMs) are expressed ubiquitously. Each of the four families of CAMs is comprised of glycosylated, membrane-bound proteins...
Cell motility | ICAM-2 | Metastasis | Neuroblastoma | CD102 | N-glycosylation | CYTOPLASMIC DOMAIN | MIGRATION | INTERCELLULAR-ADHESION MOLECULE-2 | BINDING DOMAIN | E-CADHERIN | ALPHA-ACTININ | IN-VITRO | ONCOLOGY | CANCER METASTASIS | ANCHORAGE-INDEPENDENT GROWTH | LEUKOCYTE ADHESION | Cell Adhesion Molecules - chemistry | Amino Acid Sequence | Cell Proliferation | Immunoprecipitation | Mutagenesis, Site-Directed | Humans | Actins - metabolism | Molecular Sequence Data | Immunoblotting | Glycosylation | Cell Adhesion Molecules - metabolism | Antigens, CD - metabolism | Xenograft Model Antitumor Assays | Animals | Flow Cytometry | Transfection | Neoplasm Invasiveness - pathology | Cell Line, Tumor | Antigens, CD - chemistry | Mice | Neuroblastoma - metabolism | Neuroblastoma - pathology | Cell Movement | Physiological aspects | Development and progression | Research | Cancer cells | Cell adhesion molecules | Actin
Cell motility | ICAM-2 | Metastasis | Neuroblastoma | CD102 | N-glycosylation | CYTOPLASMIC DOMAIN | MIGRATION | INTERCELLULAR-ADHESION MOLECULE-2 | BINDING DOMAIN | E-CADHERIN | ALPHA-ACTININ | IN-VITRO | ONCOLOGY | CANCER METASTASIS | ANCHORAGE-INDEPENDENT GROWTH | LEUKOCYTE ADHESION | Cell Adhesion Molecules - chemistry | Amino Acid Sequence | Cell Proliferation | Immunoprecipitation | Mutagenesis, Site-Directed | Humans | Actins - metabolism | Molecular Sequence Data | Immunoblotting | Glycosylation | Cell Adhesion Molecules - metabolism | Antigens, CD - metabolism | Xenograft Model Antitumor Assays | Animals | Flow Cytometry | Transfection | Neoplasm Invasiveness - pathology | Cell Line, Tumor | Antigens, CD - chemistry | Mice | Neuroblastoma - metabolism | Neuroblastoma - pathology | Cell Movement | Physiological aspects | Development and progression | Research | Cancer cells | Cell adhesion molecules | Actin
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2014, Volume 63, pp. 128 - 135
We aimed to develop a cell culture model of type 2 diabetes by treating SK-Hep-1 cells with four free fatty acids [i.e., palmitic acid, stearic acid (SA),...
Insulin resistance | NOX4 | Reactive oxygen species | Akt | Stearic acid | FOOD SCIENCE & TECHNOLOGY | MITOCHONDRIAL-FUNCTION | PERIPHERAL INSULIN | ENDOPLASMIC-RETICULUM STRESS | DIABETES-MELLITUS | CULTURED RAT HEPATOCYTES | GLUCOSE-HOMEOSTASIS | UNFOLDED PROTEIN RESPONSE | NOX FAMILY | LIVER | TOXICOLOGY | RECEPTOR SUBSTRATE PROTEINS | Malondialdehyde - metabolism | Phosphorylation | Reactive Oxygen Species - metabolism | Humans | Insulin Resistance | NADPH Oxidases - metabolism | NADPH Oxidase 4 | Oxidative Stress - drug effects | Cell Line, Transformed | Fatty Acids - pharmacology | Oxidases | Saturated fatty acids | Analysis | Index Medicus
Insulin resistance | NOX4 | Reactive oxygen species | Akt | Stearic acid | FOOD SCIENCE & TECHNOLOGY | MITOCHONDRIAL-FUNCTION | PERIPHERAL INSULIN | ENDOPLASMIC-RETICULUM STRESS | DIABETES-MELLITUS | CULTURED RAT HEPATOCYTES | GLUCOSE-HOMEOSTASIS | UNFOLDED PROTEIN RESPONSE | NOX FAMILY | LIVER | TOXICOLOGY | RECEPTOR SUBSTRATE PROTEINS | Malondialdehyde - metabolism | Phosphorylation | Reactive Oxygen Species - metabolism | Humans | Insulin Resistance | NADPH Oxidases - metabolism | NADPH Oxidase 4 | Oxidative Stress - drug effects | Cell Line, Transformed | Fatty Acids - pharmacology | Oxidases | Saturated fatty acids | Analysis | Index Medicus
Journal Article
International Journal of Oncology, ISSN 1019-6439, 09/2012, Volume 41, Issue 3, pp. 1036 - 1042
Hepatocellular carcinoma (HCC) is one of the most aggressive malignant diseases and is highly resistant to conventional chemotherapy. Therefore, HCC requires...
ER stress | Hepatocellular carcinoma | 5-Fluorouracil | Autophagy | Apoptosis | SURVIVAL | DEATH PROGRAM | LOCALIZATION | ACTIVATION | autophagy | PROTEIN | INDUCED APOPTOSIS | POLY(ADP-RIBOSE) PAR POLYMER | apoptosis | MECHANISMS | CANCER | 5-fluorouracil | ONCOLOGY | hepatocellular carcinoma
ER stress | Hepatocellular carcinoma | 5-Fluorouracil | Autophagy | Apoptosis | SURVIVAL | DEATH PROGRAM | LOCALIZATION | ACTIVATION | autophagy | PROTEIN | INDUCED APOPTOSIS | POLY(ADP-RIBOSE) PAR POLYMER | apoptosis | MECHANISMS | CANCER | 5-fluorouracil | ONCOLOGY | hepatocellular carcinoma
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 09/2012, Volume 26, Issue 6, p. 783
a* An in vitro NASH model was created in SK-Hep-1 cells using palmitic acid and TNF-[alpha]. a* Palmitic acid promoted TNF-[alpha]-induced cytotoxicity by...
Tumor necrosis factor | Analysis | Saturated fatty acids | Fatty acids
Tumor necrosis factor | Analysis | Saturated fatty acids | Fatty acids
Journal Article
Toxicological Research, ISSN 1976-8257, 2011, Volume 27, Issue 4, pp. 211 - 216
Herbal medicines are widely used in many countries for the treatment of many diseases. Although the use of herb extracts as alternative medicine is growing,...
Herbal medicine | Nile red | Srebp | Pparα | In vitro screening | Steatosis | SREBP | PPARα | 예방의학
Herbal medicine | Nile red | Srebp | Pparα | In vitro screening | Steatosis | SREBP | PPARα | 예방의학
Journal Article
Neurological Research, ISSN 0161-6412, 02/2007, Volume 29, Issue 1, pp. 78 - 87
Background: Many studies have suggested that hypoxia plays a crucial role in the pathogenesis of various neurological disorders. To determine protective effect...
PANAX GINSENG | CDNA MICROARRAY | HYPOXIA | CELLULAR PHYSIOLOGIC RESPONSE | cDNA microarray | Hypoxia | Panax ginseng | Cellular physiologic response | Cell Survival - drug effects | Cell Hypoxia - drug effects | Cell Hypoxia - physiology | Oligonucleotide Array Sequence Analysis - methods | Humans | Cell Cycle Proteins - metabolism | Gene Expression Profiling - methods | Neuroblastoma | Down-Regulation - drug effects | Neoplasm Proteins - metabolism | Phosphoproteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Dose-Response Relationship, Drug | Syntenins - metabolism | Tetrazolium Salts | Analysis of Variance | Panax - chemistry | Plant Preparations - pharmacology | Thiazoles | Cell Line, Tumor | Kinesin | RNA-Binding Proteins - metabolism
PANAX GINSENG | CDNA MICROARRAY | HYPOXIA | CELLULAR PHYSIOLOGIC RESPONSE | cDNA microarray | Hypoxia | Panax ginseng | Cellular physiologic response | Cell Survival - drug effects | Cell Hypoxia - drug effects | Cell Hypoxia - physiology | Oligonucleotide Array Sequence Analysis - methods | Humans | Cell Cycle Proteins - metabolism | Gene Expression Profiling - methods | Neuroblastoma | Down-Regulation - drug effects | Neoplasm Proteins - metabolism | Phosphoproteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Dose-Response Relationship, Drug | Syntenins - metabolism | Tetrazolium Salts | Analysis of Variance | Panax - chemistry | Plant Preparations - pharmacology | Thiazoles | Cell Line, Tumor | Kinesin | RNA-Binding Proteins - metabolism
Journal Article
약학회지, ISSN 0377-9556, 02/2012, Volume 56, Issue 1, pp. 14 - 19
Nonalcoholic steatohepatitis(NASH) is serious metabolic disease related to fatty acid. According to "two hit theory", fatty acid-induced oxidative stress is...
약학
약학
Journal Article
Toxicological research, ISSN 1226-8399, 2011, Volume 27, Issue 4, pp. 211 - 216
Herbal medicines are widely used in many countries for the treatment of many diseases. Although the use of herb extracts as alternative medicine is growing,...
Journal Article
Environmental Health and Toxicology, ISSN 2233-6567, 03/2011, Volume 26, p. e2011017
Objectives Manganese chloride (MnCl 2 ) is one of heavy metals for causing neurogenerative dysfunction like Manganism. The purpose of this study was to...
apoptosis | Manganese chloride (MnCl2) | Mitochondria dysfunction | Endoplasmic reticulum stress
apoptosis | Manganese chloride (MnCl2) | Mitochondria dysfunction | Endoplasmic reticulum stress
Journal Article
International journal of oncology, 09/2012, Volume 41, Issue 3, p. 1036
Hepatocellular carcinoma (HCC) is one of the most aggressive malignant diseases and is highly resistant to conventional chemotherapy. Therefore, HCC requires...
Carcinoma, Hepatocellular - physiopathology | Prospective Studies | Tumor Suppressor Protein p53 - biosynthesis | Endoplasmic Reticulum Stress - drug effects | Apoptosis - drug effects | Calcium - metabolism | Heat-Shock Proteins - metabolism | Humans | Endoplasmic Reticulum - physiology | Liver Neoplasms - drug therapy | Mitochondria - metabolism | Caspase 12 - metabolism | Autophagy - drug effects | Fluorouracil - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Endoplasmic Reticulum - drug effects | Liver Neoplasms - metabolism | Liver Neoplasms - physiopathology | Cell Line, Tumor | Fluorouracil - pharmacology | Transcription Factor CHOP - biosynthesis | Transcription Factor CHOP - metabolism | Caspase 12 - biosynthesis
Carcinoma, Hepatocellular - physiopathology | Prospective Studies | Tumor Suppressor Protein p53 - biosynthesis | Endoplasmic Reticulum Stress - drug effects | Apoptosis - drug effects | Calcium - metabolism | Heat-Shock Proteins - metabolism | Humans | Endoplasmic Reticulum - physiology | Liver Neoplasms - drug therapy | Mitochondria - metabolism | Caspase 12 - metabolism | Autophagy - drug effects | Fluorouracil - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Endoplasmic Reticulum - drug effects | Liver Neoplasms - metabolism | Liver Neoplasms - physiopathology | Cell Line, Tumor | Fluorouracil - pharmacology | Transcription Factor CHOP - biosynthesis | Transcription Factor CHOP - metabolism | Caspase 12 - biosynthesis
Journal Article
JOURNAL OF CROHNS & COLITIS, ISSN 1873-9946, 11/2019, Volume 13, Issue 11, pp. 1410 - 1417
Background and Aims: Although the incidence of inflammatory bowel disease [IBD] is increasing in Asia, data on long-term epidemiological trends are limited. We...
SK-IBD Study | POPULATION | CROHNS-DISEASE | ULCERATIVE-COLITIS | PHENOTYPE | Crohn's disease | MINNESOTA | DENMARK | prevalence | INCREASE | OLMSTED COUNTY | ulcerative colitis | COHORT | GASTROENTEROLOGY & HEPATOLOGY | incidence
SK-IBD Study | POPULATION | CROHNS-DISEASE | ULCERATIVE-COLITIS | PHENOTYPE | Crohn's disease | MINNESOTA | DENMARK | prevalence | INCREASE | OLMSTED COUNTY | ulcerative colitis | COHORT | GASTROENTEROLOGY & HEPATOLOGY | incidence
Journal Article
NEUROLOGICAL RESEARCH, ISSN 0161-6412, 2007, Volume 29, pp. S78 - S87
of various neurological disorders. To determine protective effect of Panax ginseng (PG) on hypoxia (0.1% O-2)-induced cell death in human neuroblastoma cells...
hypoxia | OXYGEN RADICALS | PROTEIN | INJURY | cDNA microarray | ISCHEMIA | REPERFUSION | Panax ginseng | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | cellular physiologic response | COMPONENT | CYTOCHROME-C RELEASE | BRAIN | EXTRACT
hypoxia | OXYGEN RADICALS | PROTEIN | INJURY | cDNA microarray | ISCHEMIA | REPERFUSION | Panax ginseng | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | cellular physiologic response | COMPONENT | CYTOCHROME-C RELEASE | BRAIN | EXTRACT
Journal Article
Journal of Endourology, ISSN 0892-7790, 10/2015, Volume 29, Issue S1, pp. P1 - A457
Journal Article