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Journal of Nuclear Medicine, ISSN 0161-5505, 10/2019, Volume 60, Issue 10, pp. 1437 - 1443
Pancreatic cancer (PC) has a very poor prognosis. Surgery is the primary treatment for patients with resectable PC; however, local recurrence, hepatic... 
Statistical analysis | Gemcitabine | Toxicity | Xenotransplantation | Antibodies | Metastasis | Survival | Metastases | Chemotherapy | Mouse devices | Pancreatic cancer | Surgery | Medical prognosis | Xenografts | Pancreas | Growth factors | Tumors | Peritoneum | Cancer
Journal Article
Annals of Oncology, ISSN 0923-7534, 10/2019, Volume 30, Issue Supplement_6
Abstract Backgrounds Promoting team-based cancer care is required. J-TOP (Japan TeamOncology Program) is consisted of multidisciplinary medical staff and we... 
Journal Article
Internal Medicine, ISSN 0918-2918, 2018
The patient was a 32-year-old Japanese woman who was given a 75-g oral glucose tolerance test at the 35th week of pregnancy and was normoglycemic. She had... 
type 1 diabetes mellitus | delivery | fulminant type 1 diabetes mellitus | diabetic ketoacidosis | pregnancy
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64570
Fatty acid synthase (FASN) expression is elevated in several cancers, and this over-expression is associated with poor prognosis. Inhibitors of FASN, such as... 
APOPTOSIS | HEPATOCELLULAR-CARCINOMA | INHIBITION | PROTEIN | CYTOSKELETON | C-11-ACETATE | MULTIDISCIPLINARY SCIENCES | GROWTH | CELL-PROLIFERATION | VON-WILLEBRAND-FACTOR | EXPRESSION | Fatty Acid Synthase, Type I - genetics | RNA, Small Interfering - genetics | Humans | Male | Gene Expression Profiling | Prostatic Neoplasms - diagnosis | Molecular Targeted Therapy | Lactones - pharmacology | Acetic Acid | Prostatic Neoplasms - genetics | Biological Transport | Neoplasms, Experimental | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | Gene Expression | Adenocarcinoma - enzymology | Enzyme Inhibitors - pharmacology | Cell Adhesion - drug effects | Adenocarcinoma - drug therapy | Fatty Acid Synthase, Type I - metabolism | Fatty Acid Synthase, Type I - antagonists & inhibitors | Cell Movement - drug effects | Adenocarcinoma - diagnosis | Animals | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Carbon Radioisotopes | RNA, Small Interfering - metabolism | Weight reducing preparations | Prognosis | RNA | Genes | Gene expression | Fatty acids | Acetates | Prevention | Synthesis | Health aspects | Prostate cancer | Tumors | Cancer | Cell proliferation | Therapy | Cytology | Hormones | Arachidonic acid | Kinases | Cancer therapies | Cell adhesion & migration | Anticancer properties | Liver cancer | Adhesive strength | Rodents | Cell adhesion | Tomography | Inhibition | Medical imaging | Invasiveness | Positron emission | Pseudopodia | Tumor cell lines | Metabolism | Ribonucleic acid--RNA | Fatty-acid synthase | Studies | Androgens | DNA microarrays | Overexpression | Cell lines | Antitumor activity | Acetic acid | Positron emission tomography | Prostate | Cell migration | Apoptosis | Ribonucleic acid
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 31, pp. 12838 - 12842
Journal Article
Hypertension (Dallas, Tex. : 1979), ISSN 0194-911X, 12/2016, Volume 68, Issue 6, pp. 1432 - 1437
The purpose of this study was to evaluate the DNA methylation levels of steroidogenic enzyme genes in aldosterone-producing adenoma (APA), and the effects of... 
DNA methylation | aldosterone-producing adenoma | KCNJ5 mutation | CYP11B2 | CYP11B1
Journal Article
by Takeuchi, Y and Mabe, K and Shimodate, Y and Yoshii, S and Yamada, S and Iwatate, M and Kawamura, T and Hotta, K and Nagaike, K and Ikezawa, N and Yamasaki, T and Komeda, Y and Asai, S and Abe, Y and Akamatsu, T and Sakakibara, Y and Ikehara, H and Kinjo, Y and Ohta, T and Kitamura, Y and Shono, T and Inoue, T and Ohda, Y and Kobayashi, N and Tanuma, T and Sato, R and Sakamoto, T and Harada, N and Chino, A and Ishikawa, H and Nojima, M and Uraoka, T and Hamada, K and Shichijo, S and Yamasaki, Y and Kato, M and Tonai, Y and Iwagami, H and Arao, M and Nakahira, H and Iwatsubo, T and Inoue, S and Matsuno, K and Nakagawa, K and Ohmori, M and Matsuura, N and Maekawa, A and Kanesaka, T and Higashino, K and Uedo, N and Ishihara, R and Mizuno, M and Matsumoto, M and Miyamoto, D and Tsuji, S and Sano, Y and Komai, S and Imai, K and Naito, M and Yoshida, Y and Yuguchi, K and Sasakawa, H and Dan, N and Sakai, A and Satomoto, Y and Taniguchi, M and Hanafusa, M and Kazunari, S and Yahaya, B and Satoshi, M and Kado, T and Nebiki, H and Sakata, Y and Yasui, Y and Kimura, A and Kashida, H and Sakurai, T and Nagai, T and Yamada, M and Kono, M and Okamoto, K and Akamine, E and Fujimoto, N and Ichinona, T and Nakao, E and Takeshita, K and Kano, Y and Matsuo, K and Nakamichi, T and Naneta, H and Hirashima, H and Nakatani, Y and Harada, Y and Ikenouchi, M and Okada, K and Yamada, T and Shoji, A and Kato, S and Suzuki, S and Yamaguchi, S and ... and Madowazu Study Grp and Madowazu Study Group and for the Madowazu Study Group
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 08/2019, Volume 171, Issue 4, pp. 229 - 229
Background: Management of anticoagulants for patients undergoing polypectomy is still controversial. Cold snare polypectomy ( CSP) is reported to cause less... 
MORTALITY | ENDOSCOPY | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | THERAPY | ANTITHROMBOTIC AGENTS | WARFARIN | CLASSIFICATION | DIRECT ORAL ANTICOAGULANTS | EUROPEAN-SOCIETY | ATRIAL-FIBRILLATION
Journal Article
Investigational New Drugs, ISSN 0167-6997, 8/2018, Volume 36, Issue 4, pp. 667 - 673
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2017, Volume 24, Issue 12, pp. 1206 - 1214
Aim: Many cohort studies have shown that increased trans fatty acid (TFA) intake increases the risk of developing coronary heart disease. However, whether TFA... 
Elaidic acid | Insulin resistance | Trans fatty acid | Diabetes mellitus | TRANS-FATTY-ACIDS | DIETARY-FAT | MYOCARDIAL-INFARCTION | FOLLOW-UP | RISK | DIABETES-MELLITUS | LOS-ANGELES | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | NATIVE JAPANESE | ADIPOSE-TISSUE | Original
Journal Article
Translational Oncology, ISSN 1936-5233, 02/2018, Volume 11, Issue 1, pp. 24 - 30
Glioblastoma is the most aggressive malignant brain tumor in humans and is difficult to cure using current treatment options. Hypoxic regions are frequently... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2014, Volume 192, Issue 3, pp. 958 - 968
Journal Article
Hypertension, ISSN 0194-911X, 01/2018, Volume 71, Issue 1, pp. 125 - 133
Aldosterone production is initiated by angiotensin II stimulation and activation of intracellular Ca signaling. In aldosterone-producing adenoma (APA) cells,... 
Transcription factors | Adenoma | Research | Aldosterone | Endoplasmic reticulum | Analysis | aldosterone-producing adenoma | Ca2+ signaling | CYP11B2 | angiotensin II | CALN1
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2018, Volume 103, Issue 3, pp. 965 - 971
Context: Aldosterone production is stimulated by activation of calcium signaling in aldosterone-producing adenomas (APAs), and epigenetic factors such as DNA... 
DIAGNOSIS | EVENTS | CYP11B2 |