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1. Oxidative stress and digestive diseases
by Hrsg.: Yoshikawa, Toshikazu
2001, 1 Auflage., ISBN 3805572301, 182
Over the past several years, there has been an extraordinarily rapid growth in our knowledge of oxidative stress and its possible involvement in both normal... 
OUR Brockhaus selection | Technik
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2. Molecular interventions in lifestyle related diseases
by Hiramatsu, Midori and Yoshikawa, Toshikazu and Packer, Lester
2006, Oxidative stress and disease, ISBN 9780824729585, 354
Antioxidants | Prevention | Oxidative stress | Lifestyles | Molecular aspects | Health aspects | Therapeutic use
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3. Full Text Introduction to serial reviews: vascular dysfunction and free radicals1,2 1Guest Editor: Toshikazu Yoshikawa 2This article is part of a series of reviews on “Vascular Dysfunction and Free Radicals.” The full list of papers may be found on the homepage of the journal
by Yoshikawa, Toshikazu
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2002, Volume 33, Issue 4, pp. 425 - 426
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4. Full Text Anoxia/reoxygenation-induced leukocyte-endothelial cell interactions1,2 1Guest Editor: Toshikazu Yoshikawa 2This article is part of a series of reviews on “Vascular Dysfunction and Free Radicals.” The full list of papers may be found on the homepage of the journal
by Kokura, Satoshi and Yoshida, Norimasa and Yoshikawa, Toshikazu
Free Radical Biology and Medicine, ISSN 0891-5849, 08/2002, Volume 33, Issue 4, pp. 427 - 432
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5. Free radicals in chemistry, biology and medicine
by Yoshikawa, Toshikazu
2000, ISBN 9781903063040, xxvii, 518
Pathophysiology | Free radicals (Chemistry)
Book
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6. Tsuda Umeko
by Yoshikawa, Toshikazu, 1888-1968
1990, Chūkō bunko, ISBN 9784122017351, 353
Tsudajuku Daigaku Presidents | Tsuda, Umeko, 1864-1929
Book
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7. Hyperthermic oncology from bench to bedside
by Kokura, Satoshi and Yoshikawa, Toshikazu and Ohnishi, Takeo
2016, ISBN 9811007195
Heat | Thermotherapy | Physiological effect | Cancer
Web Resource
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8. Hyperthermic Oncology from Bench to Bedside
by Kokura, Satoshi and Yoshikawa, Toshikazu and Ohnishi, Takeo and SpringerLink (Online service)
2016, ISBN 9811007195
This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents... 
Medicine | Oncology | Radiotherapy
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9. Food factors for health promotion
by Yoshikawa, Toshikazu, 1947
2009, Forum of nutrition, ISBN 9783805590976, Volume 61.
Metabolic Phenomena | Nutrition Therapy | Functional foods | Nutritive Value | Nutritional Physiological Phenomena | Food
Web Resource
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10. Gas biology research in clinical practice
by Yoshikawa, Toshikazu, 1947 and Naito, Yuji
2011, ISBN 3805596650
Hydrogen sulfide | Gases | Blood gases | Nitric oxide | pharmacology | diagnostic use | metabolism | Carbon monoxide | Physiological effect | therapeutic use
Web Resource
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11. Free radicals in brain physiology and disorders
by Packer, Lester and Hiramatsu, Midori and Yoshikawa, Toshikazu
1996, ISBN 9780125434454, xxx, 474
Brain | Molecular neurobiology | Pathophysiology | Free radicals (Chemistry) | Molecular aspects | Diseases
Book
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12. Full Text Role of matrix metalloproteinases in inflammatory bowel disease
by Naito, Yuji and Yoshikawa, Toshikazu
Molecular Aspects of Medicine, ISSN 0098-2997, 08/2005, Volume 26, Issue 4-5, pp. 379 - 390
Recent evidence demonstrates that the increased expression and activity of matrix metalloproteinases (MMPs) may contribute to intestinal tissue injury and... 
Inflammatory bowel disease | Adhesion molecule | Wound healing | Matrix metalloproteinase | Cytokine | Biomarkers - metabolism | Up-Regulation | Humans | Inflammatory Bowel Diseases - immunology | Cytokines - secretion | Inflammatory Bowel Diseases - physiopathology | Wound Healing | Intestines - immunology | Immunity, Innate - physiology | Inflammatory Bowel Diseases - enzymology | Matrix Metalloproteinases - immunology | Matrix Metalloproteinases - metabolism | Tissue Inhibitor of Metalloproteinase-1 - immunology | Intestines - cytology | Dextran | Sulfates | Gastrointestinal diseases
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13. Full Text Antioxidant food supplements in human health
by Hiramatsu, Midori and Packer, Lester and Yoshikawa, Toshikazu
1999, ISBN 0125435908, 539
Antioxidant Food Supplements in Human Health discusses new discoveries in the areas of oxygen and nitric oxide metabolism and pathophysiology, redox regulation... 
Antioxidants | Health aspects | Medicine: General Issues | Dietary supplements
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14. Full Text Helicobacter pylori: a ROS-inducing bacterial species in the stomach
by Handa, Osamu and Naito, Yuji and Yoshikawa, Toshikazu
Inflammation Research, ISSN 1023-3830, 12/2010, Volume 59, Issue 12, pp. 997 - 1003
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been reported to impact gastric inflammation and carcinogenesis. However, the precise... 
Allergology | Infection | Neurology | Oxidative stress | Leucocytes | Biomedicine | Immunology | Dermatology | Rheumatology | Pharmacology/Toxicology | CELLS | COCCOID FORM | NITRIC-OXIDE SYNTHASE | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | ANTIOXIDANT PROPERTIES | CELL BIOLOGY | IN-VITRO | REACTIVE OXYGEN | NEUTROPHIL CHEMOATTRACTANT-1 CINC-1 | GASTRIC-CANCER | MONGOLIAN GERBILS | Reactive Oxygen Species - metabolism | Oxidative Stress | Reactive Nitrogen Species - metabolism | Antioxidants - metabolism | Stomach Neoplasms - metabolism | Stomach - metabolism | Stomach Neoplasms - microbiology | Animals | Helicobacter pylori - metabolism | Anti-Ulcer Agents - metabolism | Proton Pump Inhibitors - metabolism | Helicobacter Infections - metabolism | Neutrophils - metabolism | Stomach - microbiology | Prevention | Helicobacter infections | Cell research | Helicobacter pylori | Cancer | Antiulcer drugs | Index Medicus
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15. Full Text Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease
by Park, Hyohun and Shima, Toshihide and Yamaguchi, Kanji and Mitsuyoshi, Hironori and Minami, Masahito and Yasui, Kohichiroh and Itoh, Yoshito and Yoshikawa, Toshikazu and Fukui, Michiaki and Hasegawa, Goji and Nakamura, Naoto and Ohta, Mitsuhiro and Obayashi, Hiroshi and Okanoue, Takeshi
Journal of Gastroenterology, ISSN 0944-1174, 1/2011, Volume 46, Issue 1, pp. 101 - 107
Hyperlipidemia, insulin resistance, and oxidative stress can heavily contribute to the initiation and progression of nonalcoholic fatty liver disease (NAFLD).... 
NAFLD | Medicine & Public Health | Fatty acid metabolism | Colorectal Surgery | Hepatology | Gastroenterology | Ezetimibe | Internal Medicine | Oncology | Insulin resistance | Lipid metabolism | Surgical Oncology | GASTROENTEROLOGY & HEPATOLOGY | Liver - pathology | Drug Administration Schedule | Fatty Liver - blood | Fatty Liver - pathology | Humans | Middle Aged | Male | Treatment Outcome | Biomarkers - blood | Fatty Liver - drug therapy | Anticholesteremic Agents - therapeutic use | Azetidines - administration & dosage | Azetidines - therapeutic use | Biopsy | Anticholesteremic Agents - administration & dosage | Liver Cirrhosis - classification | Non-alcoholic Fatty Liver Disease | Liver Cirrhosis - pathology | Adult | Female | Care and treatment | Low density lipoproteins | Anticholesteremic agents | Development and progression | Triglycerides | Insulin | Fatty acids | Cholesterol | Fatty liver | Leptin | Collagen | Universities and colleges
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16. Full Text Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population
by Sumida, Yoshio and Yoneda, Masato and Hyogo, Hideyuki and Itoh, Yoshito and Ono, Masafumi and Fujii, Hideki and Eguchi, Yuichiro and Suzuki, Yasuaki and Aoki, Noriaki and Kanemasa, Kazuyuki and Fujita, Koji and Chayama, Kazuaki and Saibara, Toshiji and Kawada, Norifumi and Fujimoto, Kazuma and Kohgo, Yutaka and Yoshikawa, Toshikazu and Okanoue, Takeshi and JSG-NAFLD and Japan Study Group of Nonalcoholic Fatty Liver Disease (JSG-NAFLD)
BMC Gastroenterology, ISSN 1471-230X, 01/2012, Volume 12, Issue 1, pp. 2 - 2
Background: A reliable and inexpensive noninvasive marker of hepatic fibrosis is required in patients with nonalcoholic fatty liver disease (NAFLD). FIB4 index... 
NAFLD | SIMPLE NONINVASIVE INDEX | CLINICAL SCORING SYSTEM | PREDICT | MARKER | SIGNIFICANT FIBROSIS | CIRRHOSIS | STEATOHEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | IV COLLAGEN 7S | HYALURONIC-ACID | Liver Cirrhosis - ethnology | Predictive Value of Tests | Liver - pathology | Age Factors | Humans | Middle Aged | Male | Alanine Transaminase - blood | Fatty Liver - ethnology | Non-alcoholic Fatty Liver Disease | Adult | Female | Retrospective Studies | Severity of Illness Index | Liver Cirrhosis - diagnosis | Fatty Liver - blood | Japan | Liver Cirrhosis - blood | Fatty Liver - diagnosis | Platelet Count | Aspartate Aminotransferases - blood | Biopsy | Biomarkers | ROC Curve | Aged | Cohort Studies | Fatty liver | Research | Biological markers | Comparative analysis | Testing | Science | Hepatitis | Liver cirrhosis | Colleges & universities
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17. Full Text Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease
by Naito, Yuji and Takagi, Tomohisa and Yoshikawa, Toshikazu
Journal of Gastroenterology, ISSN 0944-1174, 10/2007, Volume 42, Issue 10, pp. 787 - 798
Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in... 
Medicine & Public Health | Colorectal Surgery | Hepatology | activated neutrophil | Gastroenterology | posttranslational protein modification | apheresis therapy | Oncology | Internal Medicine | Surgical Oncology | inflammatory bowel disease | oxidative stress | Inflammatory bowel disease | Oxidative stress | Apheresis therapy | Activated neutrophil | Posttranslational protein modification | INTERCELLULAR-ADHESION MOLECULE-1 | CROHNS-DISEASE | PERIPHERAL-BLOOD NEUTROPHILS | CARRIER-BASED GRANULOCYTE | NITRIC-OXIDE SYNTHASE | TNB-INDUCED COLITIS | SULFATE-INDUCED COLITIS | SODIUM-INDUCED COLITIS | ACTIVE ULCERATIVE-COLITIS | GASTROENTEROLOGY & HEPATOLOGY | MONOCYTE ADSORPTION APHERESIS | Intestinal Mucosa - physiopathology | Oxidative Stress | Humans | Inflammatory Bowel Diseases - physiopathology | Leukapheresis - methods | Neutrophil Activation - physiology | Neutrophils - metabolism | Inflammatory Bowel Diseases - therapy | Protein Processing, Post-Translational - physiology | Gastrointestinal diseases
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18. Full Text Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis
by Hirotaka Nagai and Yasumasa Okazaki and Shan Hwu Chew and Nobuaki Misawa and Yoriko Yamashita and Shinya Akatsuka and Toshikazu Ishihara and Kyoko Yamashita and Yutaka Yoshikawa and Hiroyuki Yasui and Li Jiang and Hiroki Ohara and Takashi Takahashi and Gaku Ichihara and Kostas Kostarelos and Yasumitsu Miyata and Hisanori Shinohara and Shinya Toyokuni
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. E1330 - E1338
Multiwalled carbon nanotubes (MWCNTs) have the potential for widespread applications in engineering and materials science. However, because of their... 
Nanotoxicology | Inflammation | Environmental health | STRUCTURAL DEFECTS PLAY | HOMOZYGOUS DELETION | CELLS | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | MAJOR ROLE | environmental health | CELLULAR UPTAKE | FIBER | ACUTE LUNG TOXICITY | inflammation | MALIGNANT MESOTHELIOMA | ASBESTOS | nanotoxicology | Nanotubes, Carbon - poisoning | Epithelial Cells - metabolism | Humans | Epithelium - ultrastructure | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Gene Deletion | Cytokines - genetics | Cell Line | Microscopy, Electron, Transmission | Gene Expression | Microscopy, Electron, Scanning | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Epithelial Cells - ultrastructure | Rats | Nanotubes, Carbon - ultrastructure | Mesothelioma - genetics | Reverse Transcriptase Polymerase Chain Reaction | Macrophages - metabolism | Animals | Mesothelioma - metabolism | Comparative Genomic Hybridization | Mutation | Epithelium - injuries | Mesothelioma - etiology | Cytotoxicity | Carcinogens | Membranes | Cells | Nanotubes | Biological Sciences | PNAS Plus
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19. Full Text The Severity of Ultrasonographic Findings in Nonalcoholic Fatty Liver Disease Reflects the Metabolic Syndrome and Visceral Fat Accumulation
by Hamaguchi, Masahide and Kojima, Takao and Itoh, Yoshito and Harano, Yuichi and Fujii, Kota and Nakajima, Tomoaki and Kato, Takahiro and Takeda, Noriyuki and Okuda, Junichi and Ida, Kazunori and Kawahito, Yutaka and Yoshikawa, Toshikazu and Okanoue, Takeshi
The American Journal of Gastroenterology, ISSN 0002-9270, 12/2007, Volume 102, Issue 12, pp. 2708 - 2715
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is closely associated with the metabolic syndrome.AIM: We evaluated the association among the metabolic... 
DIAGNOSIS | CT | GENERAL-POPULATION | JAPAN | SONOGRAPHY | PREVALENCE | HISTOLOGY | GASTROENTEROLOGY & HEPATOLOGY | Severity of Illness Index | Japan - epidemiology | Metabolic Syndrome - diagnostic imaging | Cross-Sectional Studies | Area Under Curve | Humans | Middle Aged | Logistic Models | Male | Metabolic Syndrome - complications | Fatty Liver - diagnostic imaging | Intra-Abdominal Fat - diagnostic imaging | Biopsy | Adolescent | Ultrasonography | Adult | Female | Aged | Fatty Liver - epidemiology | Metabolic Syndrome - epidemiology | Fatty Liver - etiology | Obesity | Fatty liver
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20. Free radical biology in digestive diseases
by Naito, Yuji and Suematsu, M. 1957- (Makoto) and Yoshikawa, Toshikazu, 1947
2011, Frontiers of gastrointestinal research, ISBN 3805596103, Volume 29