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PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0133966 - e0133966
ADAMTS9 is a metalloprotease that cleaves components of the extracellular matrix and is also implicated in transport from the endoplasmic reticulum (ER) to the... 
LONGEVITY | MUTANTS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | DAF-16 | GENE-EXPRESSION | LOCI | NEMATODE CAENORHABDITIS-ELEGANS | GLYCOSYLATION | MUTATIONS | MEMBER | Metalloendopeptidases - genetics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Caenorhabditis elegans - genetics | Larva - metabolism | Caenorhabditis elegans Proteins - metabolism | Endoplasmic Reticulum - metabolism | Metalloendopeptidases - metabolism | Animals, Genetically Modified - metabolism | ADAM Proteins - metabolism | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Animals, Genetically Modified - growth & development | Animals, Genetically Modified - genetics | Larva - growth & development | Golgi Apparatus - metabolism | Insulin-Secreting Cells - cytology | ADAM Proteins - genetics | Caenorhabditis elegans Proteins - genetics | Insulin Secretion | Longevity - physiology | Type 2 diabetes | Insulin resistance | Bone morphogenetic proteins | Transforming growth factors | Secretion | Insulin-like growth factor I | Transforming growth factor-b | Diabetes mellitus | Homology | Insulin-like growth factors | Kinases | Tissues | Insulin | Golgi apparatus | Beta cells | Proteins | Signaling | Molecular modelling | Life span | Nematodes | Extracellular matrix | Metalloproteinase | Endoplasmic reticulum | Worms | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, pp. 33840 - 33840
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7664, pp. 458 - 462
The radiation-induced bystander effect (RIBE) refers to a unique process in which factors released by irradiated cells or tissues exert effects on other parts... 
Cysteine | Proteinase | p53 Protein | Radiation | Cysteine proteinase | Irradiated | Homology | Lethality | Ultraviolet | Tissues | Genomic instability | Proteins | Protease | Cathepsin B | Genetics | Deoxyribonucleic acid--DNA | Radiation effects | Stability | U.V. radiation | Radiation therapy | Gene expression | Insulin | Embryos | Radioprotection | Gamma rays | Animals | Cell death | Nematodes | Instability | Scientific imaging | Mass spectrometry | Apoptosis
Journal Article
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4418 - 9
The combined phenotype of thrombocytopenia accompanied by intellectual disability in patients with a de novo heterozygous mutation, i.e., p.Tyr64Cys in CDC42,... 
CDC42 | COMPLEX | GENETICS | MULTIDISCIPLINARY SCIENCES | MUTATION | C-ELEGANS | CDC-42 | Cdc42 protein | Thrombocytopenia | CRISPR | Deafness | Phenotypes | Camptodactyly | Intellectual disabilities | Hypothyroidism | Electron microscopy | Microscopy | Nematodes | Mutation | Platelets | Vacuoles
Journal Article
Genetics, ISSN 0016-6731, 10/2015, Volume 201, Issue 2, pp. 613 - 629
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 01/2018, Volume 22, Issue 1, pp. 232 - 241
Balancer chromosomes are critical tools for genetic research. In , reciprocal translocations that lead to aneuploidy have been widely used to maintain lethal... 
C. elegans | CRISPR/Cas9 | chromosomal rearrangements | balancer chromosomes | essential gene knockout | C. elegans | SYSTEM | RECOMBINATION | TRANSLOCATION | CRISPR/CAS9 TECHNOLOGY | REARRANGEMENTS | C. ELEGANS | CELL BIOLOGY | Aneuploidy | Animals | Caenorhabditis elegans - genetics | Chromosomes - genetics | CRISPR-Cas Systems | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 21, pp. 8079 - 8084
The unfolded protein response (UPR) is an intracellular stresssignaling pathway that counteracts the accumulation of misfolded proteins in the endoplasmic... 
Proteins | Phosphorylation | Quality assurance | Messenger RNA | Hepatocytes | RNA | Surveillance | HeLa cells | Homeostasis | Unfolded protein response | Endoplasmic reticulum quality control | Premature termination codons | ACTIVATION | MULTIDISCIPLINARY SCIENCES | QUALITY-CONTROL | MAMMALIAN-CELLS | UNFOLDED PROTEIN RESPONSE | CAENORHABDITIS-ELEGANS | MESSENGER-RNA | endoplasmic reticulum quality control | UPF1 PHOSPHORYLATION | premature termination codons | STRESS | NF-KAPPA-B | ATF6 | Proteostasis Deficiencies - metabolism | eIF-2 Kinase - metabolism | Humans | Caenorhabditis elegans Proteins - metabolism | RNA - genetics | Hepatocytes - cytology | Telomerase - genetics | Telomerase - metabolism | Nuclear Proteins - genetics | RNA Interference - physiology | Cell Survival - physiology | Protein-Serine-Threonine Kinases - metabolism | eIF-2 Kinase - genetics | Caenorhabditis elegans - growth & development | Unfolded Protein Response - genetics | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Endoplasmic Reticulum - physiology | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Proteostasis Deficiencies - genetics | Animals | Homeostasis - physiology | Caenorhabditis elegans Proteins - physiology | Mice | HeLa Cells | Larva - physiology | Caenorhabditis elegans Proteins - genetics | Cell Line, Transformed | Codon, Nonsense - genetics | Endoplasmic Reticulum Stress - physiology | Physiological aspects | Genetic aspects | Research | Health aspects | Endoplasmic reticulum | Mutation | Gene expression | Ribonucleic acid--RNA | Cells | Index Medicus | Biological Sciences
Journal Article
PLoS Genetics, ISSN 1553-7390, 01/2015, Volume 11, Issue 1
  Human BCL7 gene family consists of BCL7A, BCL7B, and BCL7C. A number of clinical studies have reported that BCL7 family is involved in cancer incidence,... 
Nematodes | Chromosomes | Genes | Worms
Journal Article