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Science, ISSN 0036-8075, 2/2009, Volume 323, Issue 5918, pp. 1205 - 1208
Journal Article
by Birney, Ewan and Stamatoyannopoulos, John A and Dutta, Anindya and Guigó, Roderic and Gingeras, Thomas R and Margulies, Elliott H and Weng, Zhiping and Snyder, Michael and Dermitzakis, Emmanouil T and Thurman, Robert E and Kuehn, Michael S and Taylor, Christopher M and Neph, Shane and Koch, Christoph M and Asthana, Saurabh and Malhotra, Ankit and Adzhubei, Ivan and Greenbaum, Jason A and Andrews, Robert M and Flicek, Paul and Boyle, Patrick J and Cao, Hua and Carter, Nigel P and Clelland, Gayle K and Davis, Sean and Day, Nathan and Dhami, Pawandeep and Dillon, Shane C and Dorschner, Michael O and Fiegler, Heike and Giresi, Paul G and Goldy, Jeff and Hawrylycz, Michael and Haydock, Andrew and Humbert, Richard and James, Keith D and Johnson, Brett E and Johnson, Ericka M and Frum, Tristan T and Rosenzweig, Elizabeth R and Karnani, Neerja and Lee, Kirsten and Lefebvre, Gregory C and Navas, Patrick A and Neri, Fidencio and Parker, Stephen C. J and Sabo, Peter J and Sandstrom, Richard and Shafer, Anthony and Vetrie, David and Weaver, Molly and Wilcox, Sarah and Yu, Man and Collins, Francis S and Dekker, Job and Lieb, Jason D and Tullius, Thomas D and Crawford, Gregory E and Sunyaev, Shamil and Noble, William S and Dunham, Ian and Denoeud, France and Reymond, Alexandre and Kapranov, Philipp and Rozowsky, Joel and Zheng, Deyou and Castelo, Robert and Frankish, Adam and Harrow, Jennifer and Ghosh, Srinka and Sandelin, Albin and Hofacker, Ivo L and Baertsch, Robert and Keefe, Damian and Dike, Sujit and Cheng, Jill and Hirsch, Heather A and Sekinger, Edward A and Lagarde, Julien and Abril, Josep F and Shahab, Atif and Flamm, Christoph and Fried, Claudia and Hackermüller, Jörg and Hertel, Jana and Lindemeyer, Manja and Missal, Kristin and Tanzer, Andrea and Washietl, Stefan and Korbel, Jan and Emanuelsson, Olof and Pedersen, Jakob S and Holroyd, Nancy and Taylor, Ruth and Swarbreck, David and Matthews, Nicholas and Dickson, Mark C and Thomas, Daryl J and Weirauch, Matthew T and Gilbert, James and ... and ENCODE Project Consortium and Baylor College of Medicine Human Genome Sequencing Center and Washington University Genome Sequencing Center and Children's Hospital Oakland Research Institute and NISC Comparative Sequencing Program and Broad Institute and The ENCODE Project Consortium
Nature, ISSN 0028-0836, 06/2007, Volume 447, Issue 7146, pp. 799 - 816
Journal Article
Hypertension Research, ISSN 0916-9636, 07/2006, Volume 29, Issue 7, pp. 515 - 521
Journal Article
by Bradley, Allan and Anastassiadis, Konstantinos and Ayadi, Abdelkader and Battey, James and Bell, Cindy and Birling, Marie-Christine and Bottomley, Joanna and Brown, Steve and Bürger, Friederike and Bult, Carol and Bushell, Wendy and Collins, Francis and Desaintes, Christian and Doe, Brendan and Aris, Economides and Eppig, Janan and Finnell, Richard and Fletcher, Colin and Fray, Martin and Frendewey, David and Friedel, Roland and Grosveld, Frank and Hansen, J and Hérault, Yann and Hicks, Geoffrey and Hörlein, Aneas and Houghton, Catherine and Hrabé De Angelis, Martin and Huylebroeck, Danny and Iyer, Vivek and Jong, Pieter and Kadin, James and Kaloff, Cornelia and Kennedy, Karen and Koutsourakis, Manousos and Kent Lloyd, K and Marschall, Susan and Mason, Jeremy and McKerlie, Colin and McLeod, Michael and Melchner, Harald and Moore, Matt and Mujica, Alejano and Nagy, Anas and Nefedov, Mikhail and Nutter, Lauryl and Pavlovic, Guillaume and Peterson, Jane and Pollock, I and Ramirez-Solis, Ramiro and Rancourt, Derrick and Raspa, Marcello and Remacle, Jacques and Ringwald, Martin and Rosen, Barry and Rosenthal, Nadia and Rossant, Janet and Ruiz Noppinger, Patricia and Ryder, S and Schick, Joel Zupicich and Schnütgen, Frank and Schofield, Christopher and Seisenberger, Claudia and Selloum, Mohammed and Simpson, Elizabeth and Skarnes, William and Smedley, Damian and Stanford, William and Francis Stewart, A and Stone, Kevin and Swan, Kate and Tadepally, Hamsa and Teboul, Jean Louis and Tocchini-Valentini, Glauco and Valenzuela, David and West, Anthony and Yamamura, Ken-Ichi and Yoshinaga, Yuko and Wurst, Martin
Mammalian Genome, ISSN 0938-8990, 10/2012, Volume 23, Issue 9-10, pp. 580 - 586
textabstractIn 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene... 
Life Sciences | Anatomy | Zoology | Cell Biology | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOME | EMBRYONIC STEM-CELLS | GENETICS & HEREDITY | Mice, Knockout - genetics | Mice | Animals | Internet | Internationality
Journal Article
by Locke, Devin P and Hillier, Ladeana W and Warren, Wesley C and Worley, Kim C and Nazareth, Lynne V and Muzny, Donna M and Yang, Shiaw-Pyng and Wang, Zhengyuan and Chinwalla, Asif T and Minx, Pat and Mitreva, Makedonka and Cook, Lisa and Delehaunty, Kim D and Fronick, Catrina and Schmidt, Heather and Fulton, Lucinda A and Fulton, Robert S and Nelson, Joanne O and Magrini, Vincent and Pohl, Craig and Graves, Tina A and Markovic, Chris and Cree, Andy and Dinh, Huyen H and Hume, Jennifer and Kovar, Christie L and Fowler, Gerald R and Lunter, Gerton and Meader, Stephen and Heger, Andreas and Ponting, Chris P and Marques-Bonet, Tomas and Alkan, Can and Chen, Lin and Cheng, Ze and Kidd, Jeffrey M and Eichler, Evan E and White, Simon and Searle, Stephen and Vilella, Albert J and Chen, Yuan and Flicek, Paul and Ma, Jian and Raney, Brian and Suh, Bernard and Burhans, Richard and Herrero, Javier and Haussler, David and Faria, Rui and Fernando, Olga and Darré, Fleur and Farré, Doménec and Gazave, Elodie and Oliva, Meritxell and Navarro, Arcadi and Roberto, Roberta and Capozzi, Oronzo and Archidiacono, Nicoletta and Valle, Giuliano Della and Purgato, Stefania and Rocchi, Mariano and Konkel, Miriam K and Walker, Jerilyn A and Ullmer, Brygg and Batzer, Mark A and Smit, Arian F. A and Hubley, Robert and Casola, Claudio and Schrider, Daniel R and Hahn, Matthew W and Quesada, Victor and Puente, Xose S and Ordõez, Gonzalo R and Ĺpez-Otín, Carlos and Vinar, Tomas and Brejova, Brona and Ratan, Aakrosh and Harris, Robert S and Miller, Webb and Kosiol, Carolin and Lawson, Heather A and Taliwal, Vikas and Martins, André L and Siepel, Adam and Roychoudhury, Arindam and Ma, Xin and Degenhardt, Jeremiah and Bustamante, Carlos D and Gutenkunst, Ryan N and Mailund, Thomas and Dutheil, Julien Y and Hobolth, Asger and Schierup, Mikkel H and Ryder, Oliver A and Yoshinaga, Yuko and De Jong, Pieter J and Weinstock, George M and Rogers, Jeffrey and Mardis, Elaine R and Gibbs, Richard A and ...
Nature, ISSN 0028-0836, 01/2011, Volume 469, Issue 7331, pp. 529 - 533
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 344 - 349
Antimalarial drugs have thus far been chiefly derived from two sources-natural products and synthetic drug-like compounds. Here we investigate whether... 
IN-VITRO | TRANSFER-RNA SYNTHETASE | MALARIA CONTROL | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | LIVER | TARGETS | PROTEIN-SYNTHESIS | NEXT-GENERATION | HEPATIC STAGES | Azabicyclo Compounds - pharmacology | Plasmodium falciparum - enzymology | Malaria, Falciparum - prevention & control | Male | Plasmodium falciparum - cytology | Azetidines - pharmacology | Plasmodium falciparum - drug effects | Cytosol - enzymology | Malaria, Falciparum - transmission | Liver - drug effects | Azabicyclo Compounds - chemical synthesis | Azabicyclo Compounds - therapeutic use | Female | Safety | Antimalarials - chemical synthesis | Disease Models, Animal | Life Cycle Stages - drug effects | Malaria, Falciparum - drug therapy | Azabicyclo Compounds - administration & dosage | Azetidines - adverse effects | Phenylurea Compounds - therapeutic use | Antimalarials - therapeutic use | Macaca mulatta - parasitology | Phenylalanine-tRNA Ligase - antagonists & inhibitors | Drug Discovery | Antimalarials - pharmacology | Animals | Azetidines - administration & dosage | Phenylurea Compounds - chemical synthesis | Antimalarials - administration & dosage | Azetidines - therapeutic use | Phenylurea Compounds - administration & dosage | Mice | Phenylurea Compounds - pharmacology | Liver - parasitology | Plasmodium falciparum - growth & development | Prevention | Antimalarials | Disease transmission | Health aspects | Transfer RNA | Proteins | Cytochrome | Malaria | Liver | Parasites | Kinases | Drug resistance | Drug dosages
Journal Article