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Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7421, pp. 547 - 551
Mitochondrial respiratory function is frequently impaired in human cancers(1-4). However, the mechanisms by which mitochondrial dysfunction contributes to... 
OXIDATIVE STRESS | INVASION | TISSUE OVERGROWTH | PATHWAY | REGENERATION | MULTIDISCIPLINARY SCIENCES | GROWTH | MIDGUT | STEM-CELL PROLIFERATION | COOPERATION | CANCER | Neoplasms - metabolism | Up-Regulation | Compound Eye, Arthropod - ultrastructure | Reactive Oxygen Species - metabolism | Oxidative Stress | JNK Mitogen-Activated Protein Kinases - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Wnt1 Protein - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Oncogene Protein p21(ras) - metabolism | Drosophila melanogaster - metabolism | Compound Eye, Arthropod - growth & development | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Compound Eye, Arthropod - pathology | Signal Transduction | Drosophila melanogaster - cytology | Mitochondria - metabolism | Imaginal Discs - pathology | Mitochondria - pathology | Clone Cells - metabolism | Disease Progression | Transcription Factors - metabolism | Animals | Clone Cells - pathology | Cell Transformation, Neoplastic | Drosophila melanogaster - enzymology | Imaginal Discs - metabolism | Neoplasms - pathology | Oncogene Protein p21(ras) - genetics | Cell interaction | Drosophila | Development and progression | Genetic aspects | Mitochondrial DNA | Observations | Properties | Tumors | Oxidative stress | Insects | Rodents | Cloning | Cell cycle | Respiratory system | Cancer | Apoptosis | Defects | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2017, Volume 19, Issue 8, pp. 996 - 1002
The Hippo pathway controls organ size and tissue homeostasis, with deregulation leading to cancer. The core Hippo components in mammals are composed of the... 
LOCALIZATION | HOMEOSTASIS | PHOSPHORYLATION | YAP/TAZ | YAP | STRESS | NLK | TAZ | CANCER | KINASES | CELL BIOLOGY | Osmotic Pressure | Phosphorylation | Cell Proliferation | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transfection | Neoplasms - genetics | Time Factors | HEK293 Cells | Muscle Proteins - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytoplasm - enzymology | Signal Transduction | Neoplasms - enzymology | p38 Mitogen-Activated Protein Kinases - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Protein Transport | Muscle Proteins - genetics | Transcription Factors - metabolism | Animals | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Smad protein | Deregulation | Transcription factors | Gene regulation | Serine | Homeostasis | Dephosphorylation | NF-AT protein | Kinases | Inactivation | Signal transduction | Localization | Deoxyribonucleic acid--DNA | Translocation | Transducers | Deactivation | Threonine | MAP kinase | Gene expression | Nuclear transport | Environmental stress | Yes-associated protein | Tea | Signaling | Cancer | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 07/2019, Volume 110, Issue 7, pp. 2284 - 2295
Cell adhesion molecule‐1 ( CADM 1) is a member of the immunoglobulin superfamily that functions as a tumor suppressor of lung tumors. We herein demonstrated... 
CADM | YAP | Hippo pathway | LATS | lung adenocarcinoma | YAP1 | LATS2 | CADM1 | YES-ASSOCIATED PROTEIN | SUPPRESSOR | ORGAN SIZE CONTROL | ADENOCARCINOMA | ADHESION | ONCOLOGY | CLONING | GENE-TRANSFER | DIFFERENTIATION | TSLC1 | EXPRESSION | Prognosis | Gene expression | Lung cancer | Analysis | Tumors | Index Medicus | Original
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 385, pp. 215 - 224
Abstract Malignant mesothelioma (MM) frequently exhibits Hippo signaling pathway inactivation (HPI) mainly due to NF2 and/or LATS2 mutations, which leads to... 
Hematology, Oncology and Palliative Medicine | Cancer stem cell | YAP | Malignant mesothelioma | Hippo pathway | Statin | CD44 | PLEURAL MESOTHELIOMA | ORGAN SIZE CONTROL | CANCER STEM-CELLS | BREAST-CANCER | ZOLEDRONIC ACID | ONCOLOGY | SIGNALING PATHWAY | DEUBIQUITINASE BAP1 | TUMOR-SUPPRESSOR | CANDIDATE ONCOGENE | MEVALONATE PATHWAY | Lung Neoplasms - drug therapy | Neurofibromin 2 - genetics | Phosphorylation | Fatty Acids, Monounsaturated - pharmacology | Mesothelioma - pathology | Neoplastic Stem Cells - drug effects | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Phosphoproteins - metabolism | Simvastatin - pharmacology | Dose-Response Relationship, Drug | Fluvastatin | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Tumor Suppressor Proteins - genetics | Hyaluronan Receptors - metabolism | Neoplastic Stem Cells - pathology | Ubiquitin Thiolesterase - metabolism | Indoles - pharmacology | Transcription, Genetic | Antineoplastic Agents - pharmacology | Binding Sites | Neurofibromin 2 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Lung Neoplasms - genetics | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | Neoplasm Invasiveness | Protein-Serine-Threonine Kinases - genetics | Mesothelioma - genetics | Phosphoproteins - genetics | Mevalonic Acid - metabolism | Ubiquitin Thiolesterase - genetics | Hyaluronan Receptors - genetics | Mesothelioma - drug therapy | Cell Movement - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Mesothelioma - metabolism | Signal Transduction - drug effects | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Medical colleges | Mesothelioma | School construction | Statins | Stem cells | Medical research | Statistical analysis | Biosynthesis | Breast cancer | Metastasis | Gene expression | Experiments | Proteins | Insects | Medical prognosis | Cell cycle | Tumorigenesis | Tumors | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2018, Volume 20, Issue 9, pp. 1 - 1098
In this Letter, the authors neglected to acknowledge funding from the Yonsei University Future-leading Research Initiative of 2017 (2017-22-007) awarded to... 
Translocation | MAP kinase | Gene regulation
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 10/2018, Volume 371, Issue 2, pp. 311 - 321
Mutations in the ( ) gene have been identified in familial ALS in human. contains a single ortholog of human called ( ). We previously established models of... 
Fused in Sarcoma (FUS) | Cabeza (Caz) | Hippo (hpo) | Mammalian sterile 20 (STE20)-kinase (MST) | Amyotrophic lateral sclerosis (ALS) | Drosophila | APOPTOSIS | ORGAN SIZE CONTROL | CELL-PROLIFERATION | AMYOTROPHIC-LATERAL-SCLEROSIS | CANCER | CELL BIOLOGY | ONCOLOGY | SIGNALING PATHWAY | DISEASE | FAT | MUTATIONS | KINASES | Sarcoma | RNA | Neurons | Locomotives | Analysis | Physiological aspects | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 05/2019, Volume 110, Issue 7, pp. 2284 - 2295
Cell adhesion molecule‐1 (CADM1) is a member of the immunoglobulin superfamily that functions as a tumor suppressor of lung tumors. We herein demonstrated that... 
Adenocarcinoma | Phosphorylation | Immunoglobulins | Prognosis | Lung | Lung cancer | Cloning | Cell membranes | Tumor cell lines | Kinases | Gene expression | Cell adhesion molecules | Cell adhesion & migration | Yes-associated protein | Proteins | Cell growth | Cell lines | Penicillin | Tumor suppressor genes | Tumors | Apoptosis
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 4313 - 4313
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 02/2012, Volume 196, Issue 4, pp. i4 - i4
Journal Article
Pathology International, ISSN 1320-5463, 06/2011, Volume 61, Issue 6, pp. 331 - 344
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 1, pp. E71 - E80
Journal Article