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Immunity, ISSN 1074-7613, 09/2016, Volume 45, Issue 3, pp. 540 - 554
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2604 - 2615
The inhibitory receptor programmed cell death 1 (PD-1) plays a major role in functional exhaustion of T cells during chronic infections and cancer, and recent... 
MEDICINE, RESEARCH & EXPERIMENTAL | HIV-INFECTION | IMMUNODEFICIENCY-VIRUS | NEGATIVE FEEDBACK-REGULATION | INTERLEUKIN-2 THERAPY | GENE-EXPRESSION | ANTIRETROVIRAL THERAPY | CHRONIC VIRAL-INFECTION | LOW-DOSE IL-2 | TUMOR-IMMUNOTHERAPY | IMMUNE EVASION | Lymphocytic choriomeningitis virus - immunology | Arenaviridae Infections - virology | Humans | Lymphocytic choriomeningitis virus - drug effects | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - administration & dosage | Immunotherapy | Hyaluronan Receptors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Female | Arenaviridae Infections - immunology | Antiviral Agents - pharmacology | Lymphocyte Activation | Mice, Inbred C57BL | Immunologic Factors - administration & dosage | Programmed Cell Death 1 Receptor - metabolism | Mice, Transgenic | Viremia - drug therapy | Antiviral Agents - administration & dosage | B7-H1 Antigen - immunology | Antibodies - pharmacology | Drug Synergism | Antibodies - administration & dosage | T-Lymphocytes, Regulatory - drug effects | Animals | B7-H1 Antigen - antagonists & inhibitors | Arenaviridae Infections - drug therapy | Viremia - virology | CD8-Positive T-Lymphocytes - virology | CD8-Positive T-Lymphocytes - drug effects | Interleukin-7 Receptor alpha Subunit - metabolism | Interleukin-2 - pharmacology | Viremia - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Viral Load - drug effects | Chronic Disease | Immunologic Factors - pharmacology | Care and treatment | Interleukin-2 | Genetic aspects | Research | T cells | Health aspects | Apoptosis | Cancer | Studies | Antiretroviral drugs | Cytokines | Lymphocytes | Infections | T cell receptors | Drug dosages | Cancer therapies | Viral infections | Immune system
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2017, Volume 214, Issue 6, pp. 1593 - 1606
Antigen-independent homeostasis of memory CD8 T cells is vital for sustaining long-lived T cell-mediated immunity. In this study, we report that maintenance of... 
BISULFITE SEQUENCING DATA | MEDICINE, RESEARCH & EXPERIMENTAL | LINEAGE RELATIONSHIP | IMMUNITY | DNA METHYLATION | PROLIFERATION | DIFFERENTIATION | IMMUNOLOGY | NAIVE | EXPRESSION | CUTTING EDGE | ANTIGEN | Humans | Adoptive Transfer | Genetic Loci | Hepatocyte Nuclear Factor 1-alpha - metabolism | Immunologic Memory - drug effects | Lymphocyte Subsets - immunology | Receptors, CCR7 - metabolism | Epigenesis, Genetic - drug effects | Homeostasis - drug effects | Cellular Reprogramming - genetics | Immunologic Memory - genetics | Lymphocyte Subsets - drug effects | Hematopoietic Stem Cell Transplantation | Homeostasis - immunology | DNA Methylation - genetics | Cellular Reprogramming - drug effects | Cell Differentiation - immunology | Phenotype | Cell Differentiation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Cell Proliferation - drug effects | Immunocompromised Host | Tissue Donors | CD8-Positive T-Lymphocytes - immunology | Genome, Human | DNA Methylation - drug effects | Cytokines - pharmacology | Homeostasis - genetics | Cell proliferation | CC chemokine receptors | Bisulfite | CD8 antigen | Homeostasis | Effector cells | Genomes | Lymphocytes T | Immunity | Gene sequencing | Interleukin 7 | Demethylation | Lymphocytes | DNA methylation | Deoxyribonucleic acid--DNA | Immunological memory | Memory cells | Cytokines | Preservation | Data acquisition | CCR7 protein | T cell receptors | Interleukin 15 | Loci | Computer memory | Stem cells | Methylation | DNA sequencing | 312
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2017, Volume 23, Issue 8, pp. 975 - 983
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 05/2010, Volume 235, Issue 1, pp. 234 - 243
The mammalian target of rapamycin (mTOR) is an intracellular kinase that regulates cell growth and metabolism. Its specific inhibitor rapamycin is currently... 
mTOR | infection | immune memory | T cells | rapamycin | vaccination | Infection | Rapamycin | Vaccination | MTOR | Immune memory |