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Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P214 - P215
Journal Article
PLoS Genetics, ISSN 1553-7390, 06/2012, Volume 8, Issue 6, p. e1002707
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2014, Volume 17, Issue 9, pp. 1156 - 1163
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2010, Volume 5, Issue 1, p. e8764
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 8, pp. 3089 - 3094
Journal Article
PLoS Medicine, ISSN 1549-1277, 12/2005, Volume 2, Issue 12, pp. 1318 - 1333
Background The proteases (secretases) that cleave amyloid-beta (A beta) peptide from the amyloid precursor protein (APP) have been the focus of considerable... 
NERVOUS-SYSTEM | MEDICINE, GENERAL & INTERNAL | GAMMA-SECRETASE INHIBITOR | PRECURSOR PROTEINS | MICROGLIAL ACTIVATION | MEMORY DEFICITS | DEPOSITION | MOUSE MODEL | IN-VIVO | GENE-EXPRESSION | MICE | Neurology | Pathology | Neuroscience | Neurosurgery | Other | Dementia
Journal Article
Circulation Research, ISSN 0009-7330, 07/2017, Volume 121, Issue 3, pp. 258 - 269
Rationale: Increasing evidence indicates that alterations of the cerebral microcirculation may play a role in Alzheimer disease, the leading cause of late-life... 
endothelium | cerebrovascular disease | brain | Alzheimer disease | oxidative stress | CEREBRAL AMYLOID ANGIOPATHY | CARDIAC & CARDIOVASCULAR SYSTEMS | CEREBROVASCULAR DYSFUNCTION | ENDOTHELIAL DYSFUNCTION | MEMORY DEFICITS | COGNITIVE IMPAIRMENT | PERIPHERAL VASCULAR DISEASE | CENTRAL-NERVOUS-SYSTEM | PRECURSOR PROTEIN | HEMATOLOGY | FUNCTIONAL HYPEREMIA | TRANSGENIC MICE | Reactive Oxygen Species - metabolism | Cerebrovascular Circulation - physiology | Macrophages - pathology | Male | Mice, Transgenic | Random Allocation | Alzheimer Disease - pathology | Brain - metabolism | Brain - blood supply | Macrophages - metabolism | Animals | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Brain - pathology | Somatosensory Cortex - blood supply | Mice | Somatosensory Cortex - metabolism | Oxidative stress | Reactive oxygen species | Neurodegenerative diseases | Cortex | Immune clearance | Transgenic mice | Innate immunity | CD36 antigen | Macrophages | Bisphosphonates | NAD(P)H oxidase | Amyloid precursor protein | Clodronic acid | Cerebrovascular system | Clonal deletion | Rodents | CYBB protein | Dementia disorders | Bone marrow | β-Amyloid | Chimeras | Alzheimer's disease | perivascular macrophages | Oxidant Stress | Animal Models of Human Disease | Vascular Type | Nitric Oxide | Vascular biology | Basic Science Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2008, Volume 105, Issue 4, pp. 1347 - 1352
Alterations in cerebrovascular regulation related to vascular oxidative stress have been implicated in the mechanisms of Alzheimer's disease (AD), but their... 
Oxidases | Oxidative stress | Reactive oxygen species | Transcriptional regulatory elements | Transgenic animals | Protein precursors | Mice | Hyperemia | Amyloids | Alzheimers disease | tg2576 | Cerebral blood flow | Alzheimer's disease | MOUSE-BRAIN | ABNORMALITIES | REDUCES OXIDATIVE DAMAGE | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | BETA-PEPTIDE | MODEL | OXYGEN SPECIES MEDIATE | cerebral blood flow | CEREBRAL-BLOOD-FLOW | FUNCTIONAL HYPEREMIA | TRANSGENIC MICE | Hyperemia - metabolism | Membrane Glycoproteins - metabolism | Humans | Membrane Glycoproteins - biosynthesis | NADPH Oxidases - metabolism | Molecular Sequence Data | Male | Free Radicals - adverse effects | Cerebrovascular Circulation - genetics | Behavioral Symptoms - metabolism | Brain - metabolism | Brain - blood supply | Membrane Glycoproteins - antagonists & inhibitors | Free Radicals - metabolism | NADPH Oxidases - genetics | Female | NADPH Oxidases - biosynthesis | Behavioral Symptoms - physiopathology | Disease Models, Animal | Amino Acid Sequence | Maze Learning - physiology | Brain - physiopathology | Mice, Inbred C57BL | NADPH Oxidases - antagonists & inhibitors | Mice, Transgenic | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Mice, Knockout | Behavioral Symptoms - genetics | Amyloid beta-Protein Precursor - genetics | Animals | Hyperemia - physiopathology | Hyperemia - genetics | Amyloid beta-Protein Precursor - biosynthesis | Control | Radicals (Chemistry) | Cerebral circulation | Influence | Glycoproteins | Research | Neurovascular diseases | Properties | Index Medicus | Biological Sciences
Journal Article
by Jun, Yang and Ibrahim-Verbaas, Carla and Vronskaya, M and Lambert, J.-C and Chung, J and Naj, Adam and Kunkle, Brian and Wang, L.-S and Bis, Joshua and Bellenguez, Céline and Harold, Denise and Lunetta, Kathryn and DeStefano, Anita L and Grenier-Boley, Benjamin and Sims, Rebecca and Beecham, G.W and Smith, Albert and Chouraki, Vincent and Hamilton-Nelson, Kara and Ikram, Arfan and Fiévet, Nathalie and Denning, Nicola and Martin, E.R and Schmidt, H and Kamatani, Y and Dunstan, M.L and Valladares, Otto and Laza, A.R and Zelenika, Diana and Ramirez, Alfredo and Foroud, Tatiana and Choi, Seung-Hoan and Boland, A and Becker, T and Kukull, W.A and Lee, Sven and Pasquier, Florence and Cruchaga, Carlos and Beekly, Duane and Fitzpatrick, Annette and Hanon, Olivier and Gill, M and Barber, Rachel and Gudnason, Vilmundur and Campion, D and Love, S and Bennett, David A and Amin, Najaf and Berr, Claudine and Tsolaki, Magda and Buxbaum, J.D and Lopez, O.L and Deramecourt, Vincent and Fox, N.C and Cantwell, Laura B and Tárraga, L and Dufouil, Carole and Hardy, J and Crane, L.M.A and Eiriksdottir, Gudny and Hannequin, Didier and Clarke, Robert and Evans, D and Mosley, Thomas H and Letenneur, L and Brayne, Carol and Maier, W and De Jager, P and Emilsson, Valur and Dartigues, Jean-François and Hampel, H and Kamboh, M. Ilyas and Bruijn, Renée and Tzourio, Christophe and Pastor, Pau and Larson, Eric B and Rotter, J.I and O'donovan, Michael and Montine, Thomas J and Nalls, Michael and Mead, Simon and Reiman, Eric and Jonsson, P.V and Holmes, C and St George-Hyslop, P.H and Boada, Mercè and Passmore, Peter and Wendland, Annika and Schmidt, R and Morgan, Kevin and Winslow, A.R and Powell, J.F and Carasquillo, M and Younkin, S and Jakobsdottir, Margret and Kauwe, J.S.K and Wilhelmsen, K.C and Rujescu, Dan and Nöthen, Markus M and Hofman, Albert and ... and IGAP Consortium
Molecular Psychiatry, ISSN 1359-4184, 01/2016, Volume 21, Issue 1, pp. 108 - 117
Journal Article